Klaus and Fanaroff's Care of the High-Risk Neonate
- 8th Edition - January 24, 2025
- Editors: Avroy A. Fanaroff, Jonathan M Fanaroff
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 2 6 0 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 2 6 1 - 3
Now in full color for the first time, Klaus and Fanaroff's Care of the High-Risk Neonate, Eighth Edition, remains your reference of choice for concise, authoritative gu… Read more
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Request a sales quoteNow in full color for the first time, Klaus and Fanaroff's Care of the High-Risk Neonate, Eighth Edition, remains your reference of choice for concise, authoritative guidance in today’s NICU. Top experts offer comprehensive yet easily accessible coverage of recent advances in this challenging field, and include personal and practical editorial comments that are the hallmark of this highly regarded text. This fully revised edition helps you take advantage of recent advances in the NICU that have improved patient care, outcomes, and quality of life, with expanded coverage of genetics and newborn screening, new diagrams and tables, many new contributing authors, and much more.
- Covers all aspects of high-risk neonatal care, including resuscitation, transport, nutrition, respiratory problems and assisted ventilation, and organ-specific care
- Features case studies, editorial comments that provide pearls and red herrings, question-and-answer sections at the end of each chapter, and interactive questions online. These popular features set this book apart from other NICU-related titles
- Contains updated content throughout; easy-to-follow clinical workflow algorithms; numerous tables and illustrations; useful appendices with drug information, normal values, and conversion charts
- Offers vastly expanded coverage of genetics, inborn errors of metabolism, and newborn screening, as well as an all-new chapter on Essential Neonatal Pharmacology for Clinical Providers in the NICU
- Includes expanded chapters on Genetics and Inborn Errors of Metabolism; also discusses the many diseases and conditions that once had poor survival prognoses, but now have improved outcomes (erythroblastosis fetalis, group B streptococcal sepsis, respiratory distress syndrome, and many more)
- Uses a new full-color format for visual appeal, readability, and quick reference.
- An ideal everyday reference for neonatologists and trainees, pediatricians, neonatal nurse practitioners, and NICU nurses
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
neonatologists, pediatricians, neonatology residents and fellows
- Title of Book
- Cover image
- Title page
- Table of Contents
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- Copyright
- Dedication
- List of Contributors
- Preface
- 1. Monitoring and Improving the Quality of Neonatal Care
- Abstract
- Clinical Microsystems and How to Assess and Monitor the Quality of Care Provided
- Why Is Quality Improvement Important in Neonatal Care?
- Improving the Quality of Care
- Conclusions
- References
- 2. Antenatal and Intrapartum Care of the High-Risk Infant
- Abstract
- Identification of the Pregnancy at Risk
- Selected Disorders of the Maternal-Fetal Interface
- Question
- References
- 3. Newborn Resuscitation and Initial Stabilization
- Abstract
- Background
- In Utero Fetal Circulation and Perfusion
- Transition at Birth
- Asphyxia
- Resuscitation of the Newborn
- Special Considerations
- Apgar Score
- Redirection of Care
- Postresuscitation Stabilization Considerations
- Questions
- References
- 4. Physical Growth Physical Examination of the Newborn Infant and the Physical Environment
- Abstract
- Determinants of Fetal Growth
- Intrauterine Growth Restriction
- Pattern of Fetal Growth
- Antenatal Assessment of Intrauterine Growth
- Epidemiology and Etiology of Fetal Growth Restriction
- Placental Contributions
- Diminished Potential: Fetal Contributions
- Identification and Management of Growth Restriction
- Small-for-Gestational-Age Infants
- Clinical Problems
- The Preterm Growth-Restricted Infant
- Growth and Long-Term Outcome
- Large for Gestational Age
- Physical Examination of the Newborn Infant
- Observation
- References
- 5. Nutrition for the High-Risk Neonate
- Abstract
- Introduction
- Water
- Electrolytes
- Parenteral Nutrition
- Enteral Nutrition
- Growth in the Neonatal Intensive Care Unit Influences Neurodevelopmental and Growth Outcomes
- Method of Feeding
- Human Milk
- Preterm Infant Formula
- Standard Infant Formulas
- Soy Formula
- Protein Hydrolysate Formula
- Postdischarge Nutrition
- Practical Hints for Enteral Nutrition
- Nutritional Assessment
- References
- 6. Selected Disorders of the Gastrointestinal Tract
- Abstract
- Definitions
- Imaging
- Diagnostic Maneuver
- Duodenal Obstruction
- Jejunoileal Anomalies
- Malrotation/Volvulus
- Meconium Ileus
- Meckel Diverticulum,
- Colonic Lesions
- Abdominal Wall Abnormalities
- Inguinal Hernia
- Blood in Stool
- Spontaneous Intestinal Perforation61
- Summary
- Acknowledgment
- References
- 7. Necrotizing Enterocolitis
- Abstract
- Etiology
- Genetics of Necrotizing Enterocolitis
- Clinical Features
- References
- 8. Genetics
- Abstract
- History and Physical Examination
- Congenital Disorders and Multiple Congenital Anomalies
- Other Newborn Screening Tests
- Neurological Presentations
- Teratogens
- References
- Resources
- 9. Inborn Errors of Metabolism and Newborn Screening
- Abstract
- Introduction
- The Neonate in Crisis—Where to Start
- Step-wise Interpretation of Critical Lab Results
- Diagnosis and Management by Group of Disorders
- Conclusion
- Questions
- References
- 10. Care of the Parents
- Abstract
- Pregnancy
- Labor and Delivery
- Effects of Social and Emotional Support on Maternal Behavior
- The Day of Delivery
- Care of the Healthy Term Infant and Parents Following Birth
- The Breast Crawl
- Early and Extended Contact for Parents and Their Infant
- Family-Centered Developmental Care
- Interventions for Families of Premature Infants: Family-Integrated Care in the NICU
- Mental Health Professionals in the NICU
- Medically Complex Infants
- Follow-Up Support
- Staff Education and Support
- Communicating Medical Information
- Summary
- Acknowledgment
- References
- 11. Developmental Care—Understanding and Applying the Science
- Abstract
- Introduction
- Defining Developmental Care
- The Evolution of Neonatal Neurodevelopmental Care
- Brain Development: The Foundation of Behavior
- The Eco-Bio-Developmental Framework
- Promoting Neuroprotection
- Care from a Trauma-Informed Lens
- The Importance of Touch and Social Connectedness
- Benefits of Loving Touch and Parental Engagement
- The Neonatal Integrative Model of Developmental Care: Where Theory and Practice Meet
- Understanding Effects of Room Design
- Facilitating Noise Reduction and Promoting Auditory Development
- Controlling Lighting and Visual Development
- Protecting and Promoting Olfaction and Gustation
- Evidenced-Based Therapeutic Interventions
- The High-Risk Neonate and the Role of Neonatal Therapists
- Interprofessional Collaboration
- Demonstrated Impact of “High-Quality Developmental Care Programs”
- Institutional Implementation of Developmental Neuroprotective Care
- Recommendations for Future Research and Implications for Clinicians
- Discussion
- References
- 12. A Spectrum of Respiratory Problems
- Abstract
- Physiologic Considerations
- Oxygen Delivery
- Practical Considerations
- General Clinical Management
- Persistent Pulmonary Hypertension of the Newborn
- Meconium Aspiration Syndrome
- Pneumothorax
- Transient Tachypnea of the Newborn
- Pulmonary Hemorrhage
- Bronchopulmonary Dysplasia/Neonatal Chronic Lung Disease
- Apnea in the Immature Infant
- Acknowledgment
- References
- 13. Assisted Ventilation
- Abstract
- Respiratory Failure
- Endotracheal Intubation
- Applied Pulmonary Mechanics
- Continuous Positive Airway Pressure
- Mechanical Ventilation
- Alternative Modes of Mechanical Ventilation
- Carbon Dioxide Elimination
- Oxygenation
- Ventilator Setting Changes and Gas Exchange
- Monitoring the Infant During Mechanical Ventilation
- Special Circumstances
- High-Frequency Ventilation
- Complications of Assisted Ventilation
- Extracorporeal Membrane Oxygenation
- Inhaled Nitric Oxide
- Summary
- Questions
- References
- 14. Glucose, Calcium, and Magnesium
- Abstract
- Introduction
- Glucose
- Calcium
- Magnesium
- Cases
- Question
- References
- 15. Neonatal Hyperbilirubinemia
- Abstract
- Formation, Structure, and Properties of Bilirubin
- Bilirubin Measurement
- Neonatal Bilirubin Metabolism
- Normal Serum Bilirubin Levels and the Natural History of Neonatal Jaundice
- Developmental Jaundice
- An Approach to the Infant With Jaundice
- Pathologic Jaundice
- Other Causes of Increased Bilirubin Production or Load on the Liver
- Bilirubin Toxicity
- Clinical Management
- Treatment
- Phototherapy
- Exchange Transfusion
- Pharmacologic Treatment
- Acknowledgment
- References
- 16. Infections in the Neonate
- Abstract
- Introduction
- Bacteria and Fungi
- Viruses
- Herpes Simplex Virus
- Protozoal Infection
- References
- 17. The Heart
- Abstract
- Physiology and Pathophysiology
- Physical Examination
- Imaging in the Neonatal Intensive Care Unit
- Diagnostic Groups of Congenital Heart Disease
- Arrhythmias in the Neonate
- References
- 18. The Kidney
- Abstract
- Introduction
- Anatomic Development
- Physiologic Development
- Evaluation of Suspected Kidney Disease in Neonates
- Acute Kidney Injury
- HYPERTENSION
- Nephrocalcinosis
- Renovascular Thrombosis
- Congenital Kidney Disease
- Hydronephrosis
- References
- 19. Hematologic Problems
- Abstract
- Red Blood Cells
- Anemia
- Polycythemia
- Erythrocyte Transfusion in the Fetus and Newborn
- White Blood Cells
- Neutrophil Diseases
- Eosinophilia
- Chronic Granulomatous Disease
- Neonatal Immune Deficiencies of Lymphocyte Lineage (T Cell, B Cell, Natural Killer Cell)
- Neonatal Thrombocytopenia
- Coagulation System in the Neonate
- Bleeding in Neonates With Normal Platelet Counts
- Thrombosis
- References
- 20. Neonatal Brain Disorders
- Abstract
- Brain Development in the Fetus and the Newborn
- Neurological Examination of the Preterm and Term-Born Infant
- Brain Injury in the Preterm Infant
- Neonatal Encephalopathy and Brain Injury in the Term Infant
- Neurological Investigations in Term Neonatal Encephalopathy
- Neurodevelopmental Correlates of Neuroimaging Patterns
- Hypothermia and Patterns of Brain Injury
- Neonatal Seizures
- Hypotonia in the Term Infant—Neuromuscular Disorders
- References
- 21. Neonatal Imaging
- Abstract
- Imaging Modalities
- Chest
- Abdomen
- Urinary Tract
- Adrenal Glands
- Central Nervous System
- Future Directions
- Key Points
- References
- 22. The Outcome of Neonatal Intensive Care
- Abstract
- Importance of Follow-Up for High-Risk Infants
- Minor Transient Problems
- Transient Neurologic Abnormality
- Persistent Neurologic Sequelae
- Physical Sequelae and Chronic Disease
- Physical Growth
- Follow-Up—Who, What, How, and When
- Timing of Follow-Up Visits
- Neurosensory and Developmental Assessment
- Early Intervention
- Points to Remember
- Early Childhood Outcomes
- School-Age Outcomes
- Young Adult Outcomes
- References
- 23. Ethical Issues
- Abstract
- Introduction
- What Is Bioethics?
- Practical Applications and Alternative Approaches
- 1. What Is the Limit of Viability?
- 2. What Challenges Should Clinicians Be Mindful of When Considering Outcomes?
- 3. How Should Clinicians Engage and Counsel Parents During Antenatal Consultation?
- 1. When Is Intensive Care Versus Palliative Care Justified?
- 2. Why Are Neurological Predictions Challenging?
- 3. How Can Clinicians Empower Parents Through Communication?
- 4. Principles of Palliative Care
- Acknowledgment
- References
- 24. Essential Neonatal Pharmacology for Clinical Providers in the NICU
- Abstract
- The Four Phases of Drug Disposition
- Therapeutic Drug Monitoring and Basic PK Calculations Help Guide Drug Dosing
- Pharmacokinetic Studies in Neonates Inform Drug Dose Recommendations
- Pharmacodynamics Inform How Drug Concentrations Are Related to Efficacy or Toxicity
- Conclusions
- Key Points
- References
- Appendix A.1. Drugs Used for Emergency and Cardiac Indications in Newborns
- Appendix A.1
- Appendix A.2. Drug Dosing Table
- Appendix B. Drug Compatibility Table
- Appendix C. Normal Values
- CHEMISTRY VALUES
- Hematologic Values
- Cerebrospinal Fluid Values
- Physiologic Parameters
- Time of First Void and Stool
- Blood Pressure
- Appendix D. Selected Procedures in Neonatology
- Introduction
- Umbilical Vessel Catheterization
- Technique of Umbilical Vessels Catheterization
- Peripherally Inserted Central Catheters
- Lumbar Puncture
- Chest Tubes
- Exchange Transfusion
- Endotracheal Intubation
- Retinopathy of Prematurity Screening
- Appendix E. Conversion Charts
- INDEX
- Confidence is ClinicalKey
- No. of pages: 550
- Language: English
- Edition: 8
- Published: January 24, 2025
- Imprint: Elsevier
- Paperback ISBN: 9780443122606
- eBook ISBN: 9780443122613
AF
Avroy A. Fanaroff
Avroy A. Fanaroff is Emeritus Professor, Pediatrics and Reproductive Biology, Case Western Reserve University School of Medicine; Emeritus Eliza Henry Barnes Chair in Neonatology, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Affiliations and expertise
Emeritus Professor, Pediatrics and Reproductive Biology, Case Western Reserve University School of Medicine; Emeritus Eliza Henry Barnes Chair in Neonatology, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USAJF
Jonathan M Fanaroff
Jonathan M Fanaroff is Co-Director, Neonatal Intensive Care Unit and Director, Rainbow Center for Pediatric Ethics, Rainbow Babies & Children's Hospital; Associate Professor Pediatrics, Case Western Reserve University School of Medicine., Cleveland, Ohio.
Affiliations and expertise
Co-Director, Neonatal Intensive Care Unit and Director, Rainbow Center for Pediatric Ethics, Rainbow Babies & Children's Hospital; Associate Professor Pediatrics, Case Western Reserve University School of Medicine., Cleveland, Ohio, USA