Kidney and Body Fluids

Foreword

Introduction

Neural Control of Renal Function

A Membrane-Molecular Approach to Renal Physiology

Phylogenetic Aspects of Ion Transport in the Kidney

Renal Cortical Interstitium and Renal Lymph with Remarks on a Stochastic Conception of the Reflexion Coefficient of the Peritubular Capillary Wall

Tubulo-Glomerular Feedback

Ontogenetic Aspects, Compensatory Hypertrophy

Renal Ontogeny and Compensatory Hypertrophy

Ontogeny of Amino Acid Reabsorption in Mammalian Kidney, the Proline Model

Para-Amino-Hippurate Uptake by Cultured Fetal Mouse Kidneys

The Developing Kidney and the Age-Dependent Adaptation to the Salt Intake

Factors Influencing Renal Sodium Excretion in the Fetal Lamb

Development of Glomerular and Tubular Function in Fetal and Newborn Pigs and their Response to Hypotonic Saline Load

Structural and Functional Compensatory Hypertrophy in Chronically Altered Rat Nephrons

Kidney Collagen Content Following Nephrectomy in Rats of Different Ages

The Role of Lymphatic Tissue in the Compensatory Renal Growth

Integration of Water and Salt Metabolism Control Mechanisms in Ontogenesis

Concluding Remarks on Renal Ontogeny and Hypertrophy

Renal Cell Cultures

Renal Cell Cultures

Hormone-Dependent Differential Growth of Renal Epithelia Cultivated In Vitro from Individual Mammalian Nephron Segments

Transport Related Properties and the Development of Polarity of an Established Epithelial Cell Line of Renal Origin

Concluding Remarks on Renal Cell Cultures

Renal Blood Flow

Introduction to Renal Blood Flow

"Redistribution" of Intrarenal Blood Flow: A Question of Microsphere Size?

General and Intrarenal Hemodynamic Alterations after Unilateral Nephrectomy in Rats

Macula Densa Feedback Regulation of Renal Hemodynamics and Renal Auto-Regulation

Autoregulation of Glomerular Filtration Rate and Renal Blood Flow in Conscious Rats

Role of Calcium and Aalbumin in the Autoregulation of Renal Blood Flow

Renal and Nephron Hemodynamics in the Dog Kidney at Varying Perfusion Pressure

Renal Vascular Tone Affects the Severity of Renal Artery Stenosis in Conscious Dogs

Effect of Indomethacin (IM) on Renal Function before and after Release of 24 Hours Unilateral (UUL) and Bilateral (BUL) Ureteral Ligation

Concluding Remarks on Renal Blood Flow

Glomerulotubular Balance

Glomerulotubular Balance

Intraluminal Control of Glomerulotubular Balance (GTB)

Intrinsic Factors Regulating Glomerulotubular Balance

Carbonic Anhydrase and Na, K-ATPase in the Regulation of Tubular Sodium Transport

The Relationship between Glomerular Tubular Balance (GTB) and the Hydrodynamics in the Mammalian Proximal Tubule

Glomerulotubular Balance: Renal Bicarbonate Reabsorption Varies with Plasma pH

Bicarbonate as Mediator of Glomerulotubular Balance during Osmotic Diuresis

Concluding Remarks on Glomerulotubular Balance

Cell Ionic Activity and Element Analysis

Element-Specific Biophysical Approaches to the Study of Intracellular Fluids

Intracellular Electrochemical Potentials of K+ Na+, Cl-and HCO-3 in Cells of Renal Tubules

Direct Measurement of Intracellular Na and K Activities in the Renal Tubular Cells with Triple-Barreled Micro-Electrodes

Membrane Potentials and Elemental Microanalysis of Renal Papillary Cells

Cytosolic Ca Ion Activity in Proximal Tubular Cells of Necturus Kidney

Concluding Remarks on Cell Ionic Activity and Element Analysis

Electrophysiology and Epithelial Transport

Introduction to Electrophysiology and Epithelial Transport: The Use of Fast Concentration Step Experiments in the Electrical Analysis of Tubular Transport

Time Course of Ouabain and Furosemide Effects on Transepithelial Potential Difference in Cortical Thick Ascending Limbs of Rabbit Nephrons

Inhibition of Fluid Reabsorption and Sodium Efflux by Low Peritubular Na and by A23187 or Quinidine in Isolated Perfused Proximal Tubules of the Rabbit

The Double-Barreled Microelectrode for the Measurement of Intracellular pH, Using Liquid Ion-Exchanger, and its Biological Application

Electrical Properties of Proximal Tubular Cell Membranes of Necturus Kidney

Changes in Membrane Resistance of Renal Proximal Tubule Induced by Cotransport of Sodium and Organic Solute

A Cyanine Dye as Indicator of Membrane Electrical Potential Differences in Brush Border Membrane Vesicles. Studies with K+ Gradients and Na+/Amino Acid Cotransport

The Stoichiometry of Na+ Coupled Anion Absorption Across the Brushborder Membrane of Rat Renal Proximal Tubule

Concluding Remarks on Electrophysiology and Epithelial Transport

Tubular Handling of Calcium and Phosphate

Mechanisms of Renal Epithelial Transport of Phosphate

Effect of pH on Renal Phosphate Transport

Control of the Tubular Handling of Phosphate: Relation between the Adaptation Mechanism and 1,25-Dihydroxyvitamin D3

Adaptation of Tubular Phosphate (Pi) Transport to Renal Mass Reduction in Thyroparathyroidectomized (TPTX) Rats

Renal Handling of Phosphate (Pi) and Calcium (Ca) in X-Linked Hypophosphatemic (HYP) Mice

Heterogeneity of Calcium Transport in the Medullary and Cortical Segments of the Thick Ascending Limb

Concluding Remarks on Tubular Handling of Calcium and Phosphate

Tubular Acidification

H+ Electrochemical Potential Profile and Luminal Acidification in Necturus Proximal Tubule

Role of Anion Transport Mechanisms in Proximal Tubule Acidification

Proton Translocation Systems in Rat Renal Brush Border Membranes

Primary Electrogenic H Pump in the Proximal Tubule

Profile of Total CO2 Movements along the Proximal Tubule of Rat Kidney

Studies on the Disequilibrium pH in Renal Tubules

Renal Tubular Net Acid (NA) Excretion: Interpretations from Potassium Imbalance

Reabsorptive Mechanism of Bicarbonate Ions Across the Luminal Membrane of Proximal Tubule

Concluding Remarks on Renal Tubular Acidification

Regulation of Water Balance

Nonosmotic Release and Vascular Effects of Vasopressin

Osmotic and Hemodynamic Control of Vasopressin: Functional and Anatomical Relationships

The Effect of Vasopressin on its Target Cell

The Role of Angiotensin II in the Control of Hypovolemic Thirst and Sodium Appetite

Effect of Osmotic Stimuli on the Concentration of Vasopressin in Jugular and Peripheral Venous Plasma

Role of Arginine Vasotocin (AVT) in Osmoregulation of Conscious Pekin Ducks at Different States of Salt and Water Balance: Central and Afferent Control of Serum AVT

Concentration of Urine in the Absence of Vasopressin: Effect of Decreased Renal Perfusion Pressure in Conscious Brattleboro Homozygotes

A Circulating Plasma Factor that Inhibits the Action of Antidiuretic Hormone

Mechanism of the Renal Hyaluronate-Hydrolase Activation in Response to ADH

Extracellular Volume Control

Introductory Remarks to the Control of the Extracellular Fluid Volume

Role of Sodium in Cerebral Control of Body Fluid Homeostasis

Postprandial Volume Regulation and Renin-Angiotensin System in Conscious Dogs

The Renal Response to Salt Loading

The Past and the Presence of a Natriuretic Hormone

Cerebral Sodium Sensors, Thirst and Sodium Balance in Sheep

Diuretic Response to Left Atrial Distension is Eliminated after Cardiac Denervation

Food Restriction, Fluid Balance and Electrolyte Balance in Sheep

Extracellular Fluid Volume in Skeletal Muscle of Man as Affected by Postural Changes

The Nature and the Mechanism of the Liver Osmoreceptor Excitation

Concluding Remarks on Control of the Extracellular Fluid Volume

Index