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Key Chiral Auxiliary Applications
- 2nd Edition - January 20, 2014
- Author: Gregory Roos
- Language: English
- eBook ISBN:9 7 8 - 0 - 1 2 - 4 1 7 1 1 5 - 2
Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important… Read more
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Request a sales quoteKey Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation.
- Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds
- Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource
Industrial, organic, and pharmaceutical chemists in industry and academia.
Acknowledgements
Foreword
Preface to the 2nd Edition
Abbreviations
1. Introduction
1.1 Background
1.2 The Chiral Auxiliary Approach
1.3 This Collection
Section A Substitution Related Processes
2. Alkylation and Related Reactions I
3. Alkylation and Related Reactions II
4. Alkylation and Related Reactions III
5. Alkylation and Related Reactions IV
Section B Addition to Unsaturated Systems
6. Electrophilic Related Addition to C=C
7. Conjugate Addition I
8. Conjugate Addition II
9. Conjugate Addition III
10. Addition To C=N Bonds
11. Addition To C=O Bonds I
12. Addition To C=O Bonds II
13. Addition To C=O Bonds III
Section C Pericyclic and Related Reactions
14. Cycloadditions I
15. Cycloadditions II
16. Rearrangements Reactions
Section D Miscellaneous Processes
17A. Kinetic Resolution-Related PROCESSES
17b. Miscellaneous Reactions
- No. of pages: 1270
- Language: English
- Edition: 2
- Published: January 20, 2014
- Imprint: Academic Press
- eBook ISBN: 9780124171152
GR
Gregory Roos
Greg Roos’ formal education comprised of a BSc (1971), BSc Honours (1972), and PhD in Organic Synthesis (1976) from the University of Cape Town. A postdoctoral fellowship with Richard Cookson at the University of Southampton was followed by a few years of pharmaceutical industrial experience. His fulltime academic career involved the University of Natal, South Africa (1981-1994), Murdoch University, Australia (1994-1997), and an extended period in the Middle East, including Sultan Qaboos University, Oman (1998-2004) and The Petroleum Institute, Abu Dhabi (2004-2008). He has successfully taught across various cultures and has received awards for his teaching contributions and innovations. Since 2009, as an adjunct Professor at Murdoch University, he shares his time between Australia and Dubai.
His research interests have focused on the development of synthetic methodology, with particular interest in asymmetric processes. This provided numerous publications in the areas of the Baylis-Hillman reaction, imidazolidinone chiral auxiliaries, and dirhodium catalyst development and applications. This period also included a number of productive collaborative visits with Tony McKervey (University College Cork & Queen’s University, Belfast), C. K. Sha (Shin Hua University, Taiwan), Mike Doyle (Trinity University, San Antonio), and Ron Warrener (CQU Rockhampton, Queensland). In 2001 he received the Merck Gold Medal for research from the South African Chemical Institute.
Affiliations and expertise
Murdoch University, Perth, Western AustraliaRead Key Chiral Auxiliary Applications on ScienceDirect