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Instrumental Thin-Layer Chromatography

  • 2nd Edition - January 14, 2023
  • Latest edition
  • Editor: Colin Poole
  • Language: English

Instrumental Thin-Layer Chromatography, Second Edition offers a comprehensive source of authoritative information on all aspects of instrumental thin-layer chromatog… Read more

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Description

Instrumental Thin-Layer Chromatography, Second Edition offers a comprehensive source of authoritative information on all aspects of instrumental thin-layer chromatography. The use of short, topic-focused chapters facilitates identifying information of immediate interest for familiar or emerging uses of thin-layer chromatography. The book gives those working in both academia and industry the opportunity to learn, refresh, or deepen their understanding of fundamental and instrumental aspects of thin-layer chromatography, as well as the tools to interpret and manage chromatographic data. The book serves as a practical consolidated guide to the selection of separation conditions and the use of auxiliary techniques.

This fully updated new edition restores the contemporary character of the book for those involved in advancing the technology, analyzing data produced, or applying the technique to new application areas. Some chapters have been consolidated to make room for topics not covered in the first edition, reflecting general changes in the field of thin-layer chromatography, especially in effects-directed detection, convenient interfaces for advanced spectroscopic detection, and greater automation possibilities. This book is a valuable reference for anyone who needs to acquire fundamental and practical information to facilitate progress in research and management functions utilizing information acquired by thin-layer chromatography.

Key features

  • Features individual chapters written by recognized authoritative and visionary experts in the field
  • Provides an overview and focused treatment of a single topic
  • Provides tables and diagrams with commonly used data to facilitate practical work, comparison of results, and decision-making
  • Places modern developments in the research literature into a general context not always apparent to inexperienced users of the technique
  • Offers comprehensive updates to all chapters
  • Includes new chapters on instrument platforms, effects-directed detection, data analysis tools, small-scale and microfluidic planar separation systems, and applications to the separation of amino acids and peptides, the analysis of saccharides and lipids, and forensic analysis

Readership

Analytical chemists, scientists, and researchers working in drug discovery, food and plant science, environmental science, and forensics; graduate students and instructors in these disciplines

Table of contents

Section 1: Fundamentals and Practice of Thin-Layer Chromatography

1. Core Concepts and Milestones in Thin-Layer Chromatography

2. Stationary Phases for Thin-Layer Chromatography

3. Solvent Selection and Method Development

4. Automated Multiple Development

5. Development by Forced-Flow and Pressurized Planar Electrochromatography

6. Instrument Platforms for Thin-Layer Chromatography

7. Theory and Instrumentation for In Situ Detection

8. Advanced Spectroscopic Detectors for Identification and Quantification: Infrared, Raman and Nuclear Magnetic Resonance

9. Advances Spectrometric Detectors for Identification and Quantification: Mass Spectrometry

10. Staining and Derivatization Techniques for Detection

11. Effects-Directed Detection: Biological Assays

12. Effects-Directed Detection: Enzymatic Assays

13. Validation of Thin-Layer Chromatographic Methods

14. Data Analysis Tools in Thin-Layer Chromatography

15. Small-scale and Microfluidic Planar Separation Systems

Section 2: Applications of Thin-Layer Chromatography

16. Applications of Thin-Layer Chromatography to the Separation of Amino Acids and Peptides

17. Applications of Thin-Layer Chromatography to the Analysis of Saccharides

18. Applications of Thin-Layer Chromatography to the Analysis of Lipids

19. Applications of Thin-layer Chromatography in Food Analysis

20. Applications of Thin-Layer Chromatography in Environmental Analysis

21. Applications of Thin-Layer Chromatography in the Pharmaceutical Industry

22. Applications of Thin-layer Chromatography in Forensic Analysis

23. Applications of Thin-Layer Chromatography in the Quality Control of Botanicals

24. Applications of Thin-Layer Chromatography in the Quality Control of Dietary Supplements

Product details

  • Edition: 2
  • Latest edition
  • Published: January 14, 2023
  • Language: English

About the editor

CP

Colin Poole

Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography – Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial “International Symposium on High-Performance Thin-Layer Chromatography”.
Affiliations and expertise
Department of Chemistry, Wayne State University, Detroit, MI, USA

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