Introduction (Richard Grol)
1. Implementation of changes in practice(Richard Grol)
2. Theories on implementation of change in healthcare (Richard Grol, Marlies Hulscher, Michel Wensing, Martin Eccles)
3. Effective implementation: a model (Richard Grol, Michel Wensing)
4. Characteristics of successful innovations (Richard Grol, Michel Wensing)
5. Clinical guidelines as a tool for implementing change in patient care (Jako Burgers, Richard Grol, Martin Eccles)
6. Determinants of effective change (Michel Wensing, Richard Grol)
7. Methods to identify implementation problems (Michel Wensing, Richard Grol)
8. Selection of strategies (Richard Grol, Michel Wensing)
9. Dissemination of innovations (Richard Grol, Michel Wensing)
10. Educational interventions (Michel Wensing, Richard Grol)
11. Feedback and reminders (Trudy van der Weijden, Richard Grol)
12. Organisational and financial interventions (Michel Wensing, Niek Klazinga, Niek Klazinga, Richard Grol)
13. Patient-mediated stategies (Michel Wensing, Glyn Elwyn, Richard Grol)
14. Multifaceted interventions (Michel Wensing, Richard Grol)
15. Effective organisation of the implementation(Richard Grol)
16. Measuring changes in patient care: development and use of indicators (Joze Braspenning, Stephen Campbell, Richard Grol)
17. Experimental evaluations of change and improvement strategies (Martin Eccles, Jeremy Grimshaw, Marion Campbell, Craig Ramsay)
18. Observational evaluations of implementation strategies(Michel Wensing, Martin Eccles, Richard Grol)
19. Process evaluation of change interventions (Marlies Hulscher, Miranda Laurant, Richard Grol)
20. Economic evaluation of implementation strategies (Johan L Severens, Jody Martens and Michel Wensing)
Epilogue (Richard Grol)