Hormones and Stem Cells

1st Edition, Volume 116 - March 19, 2021
Editor: Gerald Litwack
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 5 5 0 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 5 5 1 - 8

Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of author… Read more

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Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Cover image
Title page
Table of Contents
Copyright
Former Editors
Contributors
Preface
Chapter One: Pituitary stem cells
Abstract
1: Introduction
2: Signaling pathways in pituitary development and stem cell regulation
3: Pituitary stem cell models
Chapter Two: Wnt signaling and mammary stem cells
Abstract
1: Expression of Wnt signaling components in mammary epithelial cells
2: Growth and development of mammary gland
3: How does Wnt signaling affect mammary growth and morphogenesis?
4: Summary
Acknowledgments
Chapter Three: Thyroid hormone signaling specifies cone photoreceptor subtypes during eye development: Insights from model organisms and human stem cell-derived retinal organoids
Abstract
1: Introduction: The thyroid hormone signaling pathway
2: Thyroid hormone regulates cell fates during development
3: Cones are the color-detecting photoreceptors of the retina
4: Thyroid hormone specifies cone subtypes in mouse, chicken, and fish
5: Human retinal organoids are a model to study how thyroid hormone signaling specifies human cone subtypes
Acknowledgment
Chapter Four: Thyroid hormone and hypothalamic stem cells in seasonal functions
Abstract
1: Daily and seasonal rhythms
2: Integrated mechanisms of photoperiodism
3: Tanycytes are a heterogeneous population of multi-tasking cells
4: Tanycytes as NSCs: Implication for long-term circannual rhythms?
5: Conclusion
Acknowledgments
Chapter Five: Thyroid hormone regulation of adult neural stem cell fate: A comparative analysis between rodents and primates
Abstract
1: Introduction
2: Cellular processes underlying adult neurogenesis: Rodents vs. primates
3: How does thyroid hormone contribute to adult neurogenesis in rodents and primates throughout life?
4: How TH signaling and photoperiodism could interact to regulate adult neurogenesis
5: Conclusion
Acknowledgments
Chapter Six: Insights from single cell studies of human pancreatic islets and stem cell-derived islet cells to guide functional beta cell maturation in vitro
Abstract
1: Introduction
2: Human pancreatic islet development and (dys)function
3: Modeling human pancreas development using human pluripotent stem cells
4: Insights into human pancreas biology from single cell transcriptomics studies of pancreatic islets
5: scRNA-Seq data from human beta cell differentiation inform gaps in functional maturation
6: Discussion
Chapter Seven: Generation of high yield insulin-producing cells (IPCs) from various sources of stem cells
Abstract
1: Generation of IPCs from iPSCs
2: Generation of IPCs from ESCs
3: Generation of IPCs from MSCs
4: Conclusion
Chapter Eight: The development of adult intestinal stem cells: Insights from studies on thyroid hormone-dependent anuran metamorphosis
Abstract
1: Introduction
2: T3 and intestinal stem cell development
3: Gene regulation by TR and its roles during anuran metamorphosis
4: An essential role of TR in adult intestinal stem cell development
5: TR target genes in intestinal stem cell development
6: Conservations between Xenopus intestinal metamorphosis and mammalian intestinal maturation
7: Conclusion
Acknowledgment
Chapter Nine: Regulation of muscle stem cell function
Abstract
1: Introduction
2: Muscle stem cells are a heterogeneous population
3: Muscle stem cells and lineage progression during adult myogenesis
4: Regeneration of skeletal muscle
5: Regulation of MuSCs by hormones and other circulating factors
6: Conclusion
Acknowledgments
Chapter Ten: Estrogen receptor beta and neural development
Abstract
1: Sex hormone signaling during early neurodevelopment
2: The estrogen receptor beta (ERβ)
3: ERβ in neurodevelopment
4: Conclusion and perspectives
Chapter Eleven: Nuclear receptors linking physiology and germline stem cells in Drosophila
Abstract
1: Drosophila as a model for maternal physiological control of oogenesis
2: Nuclear receptors as molecular surveyors of physiology
3: Ecdysone signaling as a model for cell-cell communication via nuclear receptors
4: Drosophila oogenesis is fueled by stem cells
5: Multifaceted roles of NR signaling in oogenesis
6: Signaling from peripheral tissues promotes GSC maintenance
7: Conclusions and open questions
Acknowledgments
Funding
Chapter Twelve: Steroid hormones and first trimester vascular remodeling
Abstract
Introduction
1: Vascular remodeling at the maternal-fetal interface
2: Sex steroids and maternal uterine vasculature
3: Spiral artery remodeling
4: Steroid hormones regulate vascular remodeling through lipid mediators
5: Conclusions
Chapter Thirteen: Nuclear receptors and differentiation of oligodendrocyte precursor cells
Abstract
1: Nuclear receptor biology
2: From neural precursor to mature oligodendrocyte: Riding the waves
3: Remyelination in adulthood: A developmental memory?
4: Ex vivo: Evidence from the dish
5: Conclusion
Chapter Fourteen: Oxysterols and mesenchymal stem cell biology
Abstract
1: Introduction
2: Mesenchymal stem cells
3: Oxysterols
4: Oxysterol and mesenchymal stem cells
Acknowledgment

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Hormones and Stem Cells

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Gerald Litwack