Heterogeneous Catalysis in Sustainable Synthesis

1st Edition - September 17, 2021
Imprint: Elsevier
Authors: Bela Torok, Christian Schaefer, Anne Kokel
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 8 2 5 - 6
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 8 2 6 - 3

Heterogeneous Catalysis in Sustainable Synthesis is a practical guide to the use of solid catalysts in synthetic chemistry that focuses on environmentally benign applicati… Read more

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Heterogeneous Catalysis in Sustainable Synthesis is a practical guide to the use of solid catalysts in synthetic chemistry that focuses on environmentally benign applications. Collating essential information on solid catalysts into a single volume, it reveals how the efficient use of heterogeneous catalysts in synthetic chemistry can support sustainable applications. Beginning with a review of the fundamentals of heterogeneous catalytic synthesis, the book then explores the basic concepts of heterogeneous catalytic reactions from adsorption to catalyst poisons, the use of non-traditional activation methods, recommended solvents, the major types of both metal and non-metal solid catalysts, and applications of these catalysts in sustainable synthesis.

Based on the extensive experience of its expert author, this book aims to encourage and support synthetic chemists in using solid catalysts in their own work, while also highlighting the important link between heterogeneous catalysis and sustainability to all those interested.

Cover image
Title page
Table of Contents
Copyright
Preface
Chapter 1: Heterogeneous catalysis for organic synthesis: Historical background and fundamentals
Abstract
1.1: Introduction and historical background
1.2: Catalysis
1.3: Conclusions and outlook
Chapter 2: Solid catalysts for environmentally benign synthesis
Abstract
2.1: Introduction
2.2: Metal catalysts
2.3: Nonmetallic catalysts
2.4: Conclusions and outlook
Chapter 3: Application of heterogeneous catalysis in the development of environmentally benign synthetic processes
Abstract
Chapter 3.1: Hydrogenation
Abstract
3.1.1: Introduction
3.1.2: Carbon-carbon multiple bond hydrogenations: Alkenes, alkynes, dienes
3.1.3: Hydrogenation of aromatic and heteroaromatic compounds
3.1.4: Reduction of carbonyl compounds by heterogeneous catalytic hydrogenation: Aldehydes, ketones, and carboxylic acid derivatives
3.1.5: Hydrogenation of nitrogen-containing groups: NO, NN, CN, and CN groups
3.1.6: Chemo- and regioselective hydrogenation of compounds with multiple hydrogenation sensitive groups
3.1.7: Heterogeneous catalytic hydrogenations by nonconventional activation methods
3.1.8: Conclusions and outlook
Chapter 3.2: Heterogeneous catalytic hydrogenolysis of organic compounds
Abstract
3.2.1: Introduction
3.2.2: CC bonds
3.2.3: CO bonds
3.2.4: CN bonds
3.2.5: C-halogen bonds—Dehalogenation
3.2.6: NN and NO bonds
3.2.7: CS bonds
3.2.8: Hydrogenolysis of C-other elements (Si, metals) bonds
3.2.9: Hydrogenolysis of biomass-related compounds
3.2.10: Conclusions and outlook
Chapter 3.3: Heterogeneous catalytic oxidations
Abstract
3.3.1: Introduction
3.3.2: Epoxidation reactions
3.3.3: Dihydroxylation reactions
3.3.4: Wacker-type oxidation reactions
3.3.5: Oxidative cleavage of hydrocarbons
3.3.6: Oxidation of CO and CN bonds
3.3.7: Dehydrogenation and aromatization of CC and CX bonds
3.3.8: Conclusions and outlook
Chapter 3.4: Metathesis by heterogeneous catalysts
Abstract
3.4.1: Introduction
3.4.2: Cross-metathesis
3.4.3: Ring-closing metathesis
3.4.4: Ring-opening metathesis
3.4.5: Alkyne metathesis
3.4.6: Heterogeneous catalytic asymmetric metathesis
3.4.7: Metathesis applied to bioderived alkenes
3.4.8: Conclusions and outlook
Chapter 3.5: Friedel-Crafts and related reactions catalyzed by solid acids
Abstract
3.5.1: Introduction
3.5.2: Alkylation, hydroxyalkylation
3.5.3: Acylation
3.5.4: Friedel-Crafts cycliacyalkylations
3.5.5: Halogenation
3.5.6: Nitration
3.5.7: Sulfonation
3.5.8: Conclusions and outlook
Chapter 3.6: Cross-coupling reactions for environmentally benign synthesis
Abstract
3.6.1: Introduction
3.6.2: The Heck coupling
3.6.3: The Suzuki coupling
3.6.4: The Hiyama coupling
3.6.5: The Negishi coupling
3.6.6: The Kumada coupling
3.6.7: The Sonogashira coupling
3.6.8: The Tsuji-Trost allylation
3.6.9: Coupling reactions not involving a CC bond formation
3.6.10: Conclusions and outlook
Chapter 3.7: Multicomponent reactions
Abstract
3.7.1: Introduction
3.7.2: Carbonyl-based multicomponent reactions
3.7.3: Isocyanide-based reactions
3.7.4: Conclusions and outlook
Chapter 3.8: Ring transformations by heterogeneous catalysis
Abstract
3.8.1: Introduction
3.8.2: Cyclization
3.8.3: Ring opening reactions
3.8.4: Conclusions and outlook
Chapter 3.9: Heterogeneous catalytic rearrangements and other transformations
Abstract
3.9.1: Rearrangements
3.9.2: Aldol and related reactions
3.9.3: Condensations
3.9.4: Hydrolysis
3.9.5: Introduction and removal of protecting groups
3.9.6: Hydroformylations
3.9.7: Conclusions and outlook
Chapter 3.10: Asymmetric synthesis by solid catalysts
Abstract
3.10.1: Introduction
3.10.2: Oxidation reactions
3.10.3: Hydrogenation
3.10.4: Aldol-reaction and related chemistry
3.10.5: Multicomponent and various other reactions
3.10.6: Conclusions and outlook
Index

Bela Torok

Dr Torok received his Ph.D. from the University of Szeged, Hungary in Organic Chemistry/Heterogeneous Catalysis in 1995. After receiving his Ph.D. he did postdoctoral training with the 1994 Nobel Laureate George Olah at the University of Southern California in Los Angeles working on the development of environmentally benign alkylate gasoline production. He has held various faculty appointments at Michigan Technological University and the University of Massachusetts Boston, where he is currently a Professor of Chemistry. In 2011/12 he was a visiting professor at the Massachusetts Institute of Technology working with the 2005 Nobel Laureate Richard Schrock on the development of new alkene metathesis catalysts. His main research focus is on the design of new green chemistry processes for the synthesis of fine chemicals and pharmaceuticals. The major tools applied in his research are heterogeneous catalysis (both metal and solid acid), catalytic hydrogenation, the application of aqueous medium in organic synthesis and unusual activation methods such as microwave and ultrasonic irradiation. He has published over 150 papers and book chapters, many of them in the journal Green Chemistry and Green Chemistry related books.

Affiliations and expertise

Professor of Chemistry, Department of Chemistry, University of Massachusetts, Boston, USA

Christian Schaefer

Dr Schäfer received his Dipl.-Ing. degree in chemistry after studies at the Technical University Darmstadt and University Bordeaux 1. Subsequently he moved to University of Strasbourg and worked on metal-mediated cyclization reactions under the supervision of Michel Miesch. After obtaining his PhD from the University of Strasbourg in 2013, he moved to the University of Massachusetts Boston to work as a postdoctoral researcher with Béla Török. He is currently a lecturer and research scientist at UMass Boston, where his research interests are in the development of new methods for green transformations with a focus on catalytic hydrogenation in water.

Affiliations and expertise

Lecturer and Research Scientist, Department of Chemistry, University of Massachusetts, Boston, USA

Anne Kokel

Anne Kokel has been a researcher in Green Chemistry at the University of Massachusetts, Boston, USA since 2015, where her work focuses on the design of green methods using energy-efficient techniques, non-toxic chemicals and recyclable processes for the synthesis of compounds with biomedical relevance. After studying at the Universite de Bourgogne, France, she went on to complete her MA at Université Savoie Mont Blanc, France, before joining the University of Louisiana at Lafayette, USA in 2014. With a strong knowledge of green chemistry, toxicology and medicinal chemistry, she has published multiple papers, reviews and book chapters.

Affiliations and expertise

Researcher in Green Chemistry, Department of Chemistry, University of Massachusetts, Boston, USA

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Heterogeneous Catalysis in Sustainable Synthesis

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Bela Torok

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