Herbal Biomolecules in Healthcare Applications
- 1st Edition - October 5, 2021
- Imprint: Academic Press
- Editors: Subhash C. Mandal, Amit Kumar Nayak, Amal Kumar Dhara
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 8 5 2 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 0 8 0 - 5
Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecu… Read more
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Request a sales quoteHerbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful.
- Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry
- Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields
- Includes updated literature review along with practical examples and research case studies
Researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products. Advanced students studying natural products
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- About the editors
- Foreword by Bharat B. Aggarwal
- Foreword by Satyajit D. Sarker
- Foreword by Rob Verpoorte
- Preface
- Chapter 1. Introduction to herbal biomolecules
- Abstract
- 1.1 Introduction
- 1.2 Herbal biomolecules
- 1.3 Therapeutic activities of herbal biomolecules
- 1.4 Standardization of herbal biomolecules
- 1.5 Regulatory consideration
- 1.6 Future prospective and challenges
- References
- Further reading
- Chapter 2. Extraction of herbal biomolecules
- Abstract
- 2.1 Introduction
- 2.2 Conventional extraction techniques
- 2.3 Modern Methods of Extraction
- 2.4 Conclusion
- References
- Chapter 3. Purification of herbal biomolecules
- Abstract
- 3.1 Introduction
- 3.2 Purification of herbal biomolecules
- 3.3 Volatile and nonvolatile compound extraction from herbal plant extract and its identification
- 3.4 Bioassay-guided isolation
- 3.5 Solvent–solvent extraction method by using separating funnel for the bioactive compound isolation
- 3.6 Identification of functional groups in crude extracts using Fourier transform infrared spectroscopy
- 3.7 Medium-pressure liquid chromatography
- 3.8 LC-ESI-MS/MS QTOF analysis or identification of bioactive compound
- 3.9 Gas chromatography-mass spectrometry analysis of bioactive compounds present in plants extracts
- 3.10 Preparative high-performance liquid chromatography analysis
- 3.11 Identification and structure elucidation by nuclear magnetic resonance spectroscopy
- 3.12 Conclusion
- Acknowledgments
- References
- Chapter 4. Chemistry of herbal biomolecules
- Abstract
- 4.1 Introduction
- 4.2 Primary metabolite-based biomolecules
- 4.3 Secondary metabolites
- 4.4 Conclusion
- References
- Chapter 5. Variation of biomolecules in plant species
- Abstract
- 5.1 Introduction—primary and secondary metabolites
- 5.2 Variations of biomolecules in the herbal healthcare context
- 5.3 Factors affecting the variation of biomolecules in plant species
- 5.4 Quantifying the variation of biomolecules in plant species
- 5.5 Variation of primary metabolites in plant species
- 5.6 Variation in secondary metabolites of plant species
- 5.7 OMICs technology solution for the variation of biomolecules
- 5.8 Conclusion and prospects
- Acknowledgments
- References
- Chapter 6. Phytopharmacology of herbal biomolecules
- Abstract
- 6.1 Introduction
- 6.2 Emerging need for phytotherapy
- 6.3 Herbal biomolecules for central nervous system ailments
- 6.4 Plants’ biomolecules for cardiovascular ailments
- 6.5 Antimicrobial
- 6.6 Plant-based antiinflammatory biomolecules
- 6.7 Herbal biomolecules as anticancer agents
- 6.8 Herbal biomolecules as hepatoprotectives
- 6.9 Conclusion
- References
- Chapter 7. Analytical characterization of herbal biomolecules
- Abstract
- 7.1 Introduction to analytical techniques for herbal biomolecules
- 7.2 Spectroscopic techniques
- 7.3 Mass spectrometric techniques
- 7.4 Chromatography
- 7.5 Biochemical methods
- 7.6 Combining several techniques to characterize molecules
- 7.7 Conclusion and prospects
- Acknowledgment
- References
- Chapter 8. Bioactivity characterization of herbal molecules
- Abstract
- 8.1 Antimicrobial uses of herbal compounds for dental disease
- 8.2 Antimicrobial uses of herbal compounds for respiratory infectious diseases
- 8.3 Antimicrobial uses of herbal compounds for gastrointestinal diseases
- 8.4 Identification and characterization of bioactivity of biomolecules of herbal origin with analgesic and antiinflammatory activities for medical potential
- 8.5 Machine learning in search for new herbal molecules origin with potential application for drugs development
- References
- Chapter 9. Herbal carbohydrates in healthcare
- Abstract
- 9.1 Introduction
- 9.2 Material and methods
- 9.3 Carbohydrates—functions and construction
- 9.4 Carbohydrates as a pharmacological raw material
- 9.5 Functionality
- 9.6 Clinical Significance
- 9.7 Concusion
- References
- Chapter 10. Herbal oil in healthcare
- Abstract
- 10.1 Introduction
- 10.2 Sources
- 10.3 Chemical composition
- 10.4 Therapeutic potential
- 10.5 Modern trends of herbal oils
- 10.6 Conclusion and future perspective
- Acknowledgment
- References
- Chapter 11. Essential oils and their bioactive molecules in healthcare
- Abstract
- 11.1 Introduction
- 11.2 Sources of essential oils
- 11.3 Chemistry of essential oils
- 11.4 Methods of extraction and analysis of essential oils
- 11.5 Biological activities of essential oils
- 11.6 Trade and commercial applications of essential oils in healthcare
- 11.7 Risks and dangers of essential oils
- 11.8 Conclusion
- References
- Chapter 12. Herbal glycosides in healthcare
- Abstract
- 12.1 Introduction
- 12.2 Anthraquinone glycosides
- 12.3 Cardiac glycosides
- 12.4 Coumarin glycosides
- 12.5 Cyanogenic glycosides
- 12.6 Flavonoid glycosides
- 12.7 Glucosinolates
- 12.8 Phenol glycosides
- 12.9 Saponin glycosides
- References
- Chapter 13. Herbal alkaloids in healthcare
- Abstract
- 13.1 Introduction
- 13.2 Structure, characterization and sources of alkaloids
- 13.3 Relationship of alkaloids structure and chemistry on pharmacological properties
- 13.4 Toxic effect of herbal alkaloids and relation to healthcare
- 13.5 How herbal alkaloids are used to combat chronic diseases
- 13.6 Conclusions
- Acknowledgments
- References
- Chapter 14. Herbal flavonoids in healthcare
- Abstract
- 14.1 Introduction
- 14.2 Brief account on herbal medicines
- 14.3 Causes for uprising in the application of herbal medicines
- 14.4 Classification of herbal flavonoids and their chemical structure
- 14.5 Flavonoid rich food and medicinal plants
- 14.6 Various fields of application of flavonoids in the healthcare system
- 14.7 Future research improvement on flavonoids
- 14.8 Conclusion
- References
- Chapter 15. Herbal terpenoids in healthcare
- Abstract
- 15.1 Introduction
- 15.2 Medicinal plants as source of terpenoids
- 15.3 Pharmacological effects of terpenoids
- 15.4 Antimicrobial effects of terpenoids
- 15.5 Conclusion
- References
- Chapter 16. Herbal coumarins in healthcare
- Abstract
- 16.1 General description of coumarins
- 16.2 Bioactivity studies performed on the coumarins
- 16.3 Conclusion
- References
- Chapter 17. Plant biomolecule antimicrobials: an alternative control measures for food security and safety
- Abstract
- 17.1 Introduction
- 17.2 Conclusion and future prospect
- Acknowledgments
- References
- Chapter 18. Antidiabetic herbal biomolecules
- Abstract
- 18.1 Diabetes mellitus
- 18.2 Glucose homeostasis
- 18.3 Insulin resistance
- 18.4 Metabolic pathways and their relationship with diabetes mellitus
- 18.5 Enzymes
- 18.6 Causes associated with diabetes mellitus
- 18.7 Oxidative stress
- 18.8 Control of diabetes mellitus
- 18.9 Compounds with antidiabetic properties
- 18.10 Conclusions
- References
- Chapter 19. Herbal biomolecules: anticancer agents
- Abstract
- 19.1 Introduction
- 19.2 Cancer: plant-based treatment
- 19.3 Plants secondary metabolites as anticancer drugs
- 19.4 Plant collection, extraction, identification, and anticancer a activity of HBs
- 19.5 Modern drugs for cancer treatment and its limitations
- 19.6 Present cancer therapy via phytochemicals: as a novel approach
- 19.7 Herbal biomolecules with anticancer activity
- 19.8 Various schemes for the development of anticancer herbal biomolecules
- 19.9 Conclusion and future prospects
- References
- Chapter 20. Herbal biomolecules acting on central nervous system
- Abstract
- 20.1 Contribution of plants to Central Nervous System science
- 20.2 Herbal biomolecules with central nervous system activities
- 20.3 Biomolecules with cholinergic stimulant effect
- 20.4 Biomolecules with Monoamine Stimulant effect
- 20.5 Biomolecles with Purinergic stimulant effects
- 20.6 Biomolecules with Cognitive enhancing effects
- 20.7 Herbal sedatives and anxiolytics
- 20.8 Psychotherapeutic herbs
- 20.9 Analgesic herbs
- 20.10 Local anesthetic biomolecules
- 20.11 Hallucinogenic plants
- References
- Chapter 21. Herbal biomolecules as nutraceuticals
- Abstract
- 21.1 Introduction
- 21.2 Classification of the herbal biomolecules
- 21.3 Conclusion
- References
- Chapter 22. Herbal immunomodulators
- Abstract
- 22.1 Introduction
- 22.2 Methods
- 22.3 Results
- 22.4 Discussion and conclusion
- Conflict of interest
- References
- Chapter 23. Herbal antilithiatic biomolecules
- Abstract
- 23.1 Introduction
- 23.2 Kidney stones
- 23.3 Herbal antilithiatic biomolecules
- 23.4 Conclusions and future perspective
- References
- Chapter 24. Herbal aphrodisiac biomolecules in the management of male reproductive and sexual problems: connecting nature with clinics
- Abstract
- 24.1 Introduction
- 24.2 Traditional herbal medicine
- 24.3 Aphrodisiacs
- 24.4 Potential mechanism of action of aphrodisiac biomolecules
- 24.5 Conclusion
- References
- Chapter 25. Herbal biopolysaccharides in drug delivery
- Abstract
- 25.1 Introduction
- 25.2 Classifications and sources of herbal biopolysaccharides
- 25.3 Herbal polysaccharides and their uses in drug delivery
- 25.4 Conclusion
- References
- Chapter 26. Standardization of herbal biomolecules
- Abstract
- 26.1 Introduction
- 26.2 Authentication and standardization of herbal drugs
- 26.3 Safety and toxicity profiling of herbal medicines
- 26.4 Conclusion
- References
- Chapter 27. Regulatory considerations of herbal biomolecules
- Abstract
- 27.1 Introduction
- 27.2 Biomolecules
- 27.3 Food and drug administration regulations on botanical drugs/ biomolecules
- 27.4 Marketing of herbal biomolecules
- 27.5 Investigational new drug application for herbal biomolecules
- 27.6 New drug application for herbal biomolecules
- 27.7 Role of code of federal regulations in regulation of biomolecules
- 27.8 World Health Organization regulation policy on herbal biomolecules
- 27.9 Conclusion
- References
- Chapter 28. Clinical trials of herbal biomolecules
- Abstract
- 28.1 Introduction
- 28.2 Methods
- 28.3 Results
- 28.4 Discussion and conclusion
- Conflict of interest
- References
- Index
- Edition: 1
- Published: October 5, 2021
- Imprint: Academic Press
- No. of pages: 750
- Language: English
- Paperback ISBN: 9780323858526
- eBook ISBN: 9780323900805
SM
Subhash C. Mandal
Dr. Subhash C. Mandal, PhD is Professor at Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. Professor Mandal is the recipient of prestigious awards including Endeavour Research Award, Government of Australia; Distinguished Education & Research Award, AAiPS, USA; Talented Scientist Award, University of Colombo, Sri Lanka; SAARC Fellowship Award, University Grants Commission (UGC), Bangladesh; Fast Track Young Scientist Award, Department of Science and Technology , UGC Research Award, India and Outstanding University Teachers’ Award , Department of higher education , Government of West Bengal , India. He has supervised more than 30 doctoral and 25 M. Pharm scholars and has more than 300 research publications, several patents, books and book chapters to his credit. Professor Mandal has delivered more than 50 research presentations around the globe, has chaired many international conferences, and successfully completed more than 10 government-funded research projects. He is reviewer and board member of several high-impact journals and is a recognized host scientist for many international research programs with developing countries sponsored by the Indian Government. He has visited more than 30 countries for various scientific deliberations, collaborations and exchange programmes.
Affiliations and expertise
Professor, Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Kolkota, IndiaAN
Amit Kumar Nayak
Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
Affiliations and expertise
Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, IndiaAD
Amal Kumar Dhara
Dr. Amal Kumar Dhara (MPharm, PhD) has over 20 years of teaching and research experience in the fields of Pharmacology and Toxicology, especially in the areas of neuropharmacology and anti-inflammatory, antiulcer, and free radical scavenging activities of indigenous Indian plants. He earned his PhD in Pharmaceutical Sciences from Jadavpur University, Kolkata, West Bengal, India. Currently, Dr. Dhara works as a Lecturer in Pharmacy (Associate Professor) at Contai Polytechnic, Purba Medinipur, West Bengal, India.
Affiliations and expertise
Department of Pharmacy, Contai Polytechnic, Government of West Bengal, Contai, Purba Medinipur, West Bengal, IndiaRead Herbal Biomolecules in Healthcare Applications on ScienceDirect