Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research collates fundamental information about the structure and function of hormones from basic biology to… Read more
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Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research collates fundamental information about the structure and function of hormones from basic biology to clinical use.
The handbook offers a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors and signalling pathways, and the biological activities they regulate.
The evolution of hormones and gene families is also covered both in the text and in online ancillaries.
Users will find simple and visual ways to learn key molecular information. Chapters and online ancillary resources integrate additional sections, providing a comparative molecular, functional, and evolutionary consideration.
Provides the only single resource available with concise, yet informative descriptions of hormones in vertebrates, invertebrates, and plants
Presents hormones in groups according to their origin, so that readers can easily understand their inter-relation
Includes comparative information on the structures and functions of hormones enabling readers to understand both general and specific actions in and across species
Ancillary website hosts additional information, including sequence data, comparative data, figures, and tables
Biomedical and biological researchers in human, mammalian, comparative endocrinology, and biochemistry
About the Editors
Editors
Associate Editors
The Japan Society for Comparative Endocrinology
List of Contributors
Preface
List of Abbreviations
Bioactive Molecules and Technical Terms Related to Hormones
Part I: Peptides and Proteins in Vertebrates
Section I.1: Neuropeptides
Chapter 1. RFamide Peptide Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 1A. Gonadotropin-Inhibitory Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 1B. Kisspeptin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 1C. PQRFamide Peptide
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 1D. Pyroglutamylated RFamide Peptide
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 1E. Prolactin-Releasing Peptide
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 2. Corticotropin-Releasing Hormone Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 2A. Corticotropin-Releasing Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 2B. Urotensin-I
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 2C. Urocortins
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 2D. Sauvagine
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 3. Gonadotropin-Releasing Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 4. Thyrotropin-Releasing Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 5. Somatostatin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 6. Neurohypophysial Hormone Family
History
Structure
Receptors
Biological Functions
References
Subchapter 6A. Vasopressin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 6B. Vasotocin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 6C. Oxytocin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 6D. Non-Mammalian Oxytocin Family Peptides
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 7. Opioid Peptide Family
Abstract
History
Structure
Receptors
Biological Functions
References
Subchapter 7A. Enkephalin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 7B. Dynorphin/α-Neo-endorphin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 7C. Nociceptin/Orphanin FQ
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 7D. Endomorphin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
References
Subchapter 7E. Dermorphin
Abstract
Discovery
Structure
Properties
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
References
Chapter 8. Agouti Family
Abstract
History
Structure
Receptors
Biological Functions
References
Subchapter 8A. Agouti-Signaling Protein
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 8B. Agouti-Related Protein
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 9. Tachykinin Family
Abstract
History
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 9A. Substance P/Neurokinin A
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 9B. Neurokinin B
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 10. Appetite-Regulating Peptides
Abstract
History
Structures and Biological Functions
References
Subchapter 10A. Melanin-Concentrating Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 10B. Orexin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 10C. Cocaine- and Amphetamine-Regulated Transcript
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 11. Urotensin II
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 12. Neurotensin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 13. Neuromedin U/S
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Section I.2: Adenohypophysial Hormones
Chapter 14. Glycoprotein Hormone Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 14A. Follicle-Stimulating Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 14B. Luteinizing Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 14C. Thyroid-Stimulating Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 15. Growth Hormone/Prolactin Family
Abstract
History
Structure
Receptors
Biological Functions
References
Subchapter 15A. Growth Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 15B. Prolactin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 15C. Somatolactin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 16. Proopiomelanocortin Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 16A. Adrenocorticotropic Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 16B. Melanocyte-Stimulating Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 16C. Endorphin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Section I.3: Gastrointestinal Hormones
Chapter 17. Glucagon Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 17A. Glucagon
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 17B. Gastric Inhibitory Peptide
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 17C. Glucagon-Like Peptide-1
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 17D. Glucagon-Like Peptide-2
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Chapter 18. Secretin (Pituitary Adenylate Cyclase-Activating Polypeptide) Family
Abstract
History
Structure
Receptors
Biological Functions
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 18A. Secretin
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 18B. Growth Hormone-Releasing Hormone
Abstract
Discovery
Structure
Synthesis and Release
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
Chapter 102. Anti-Thyroid Hormone Active Chemicals
Abstract
History
Structure
Biological Functions and Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 102A. Tetrabromobisphenol A
Abstract
Discovery
Structure
Synthesis and Release
Biological and Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 102B. Perchlorate
Abstract
Discovery
Structure
Synthesis and Release
Biological and Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Part VI: Gasotransmitters
Chapter 103. Gasotransmitter Family
Abstract
History
Structure
Receptors
Biological Functions
References
Subchapter 103A. Nitric Oxide
Abstract
Discovery
Structure
Synthesis, Release, and Metabolism
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 103B. Carbon Monoxide
Abstract
Discovery
Structure
Synthesis, Release, and Metabolism
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Subchapter 103C. Hydrogen Sulfide
Abstract
Discovery
Structure
Synthesis, Release, and Metabolism
Receptors
Biological Functions
Pathophysiological Implications
Supplemental Information Available on Companion Website
References
Supplemental Information
Index
No. of pages: 674
Language: English
Published: August 26, 2015
Imprint: Academic Press
Hardback ISBN: 9780128010280
eBook ISBN: 9780128010679
YT
Yoshio Takei
President of the Japan Society for Comparative Endocrinology; Professor, Laboratory of Physiology, Department of Marine Bioscience Atmosphere and Ocean Research Institute, The University of Tokyo, Chiba, Tokyo, Japan
Affiliations and expertise
Professor, Laboratory of Physiology, Department of Marine Bioscience Atmosphere and Ocean Research Institute, The University of Tokyo, Chiba, Tokyo, Japan
HA
Hironori Ando
Sado Marine Biological Station, Faculty of Science, Niigata University, Niigata, Japan. His specific research interest involves neuroendocrine regulation of behavioral and physiological functions in diadromous migratory fish, such as salmonids and puffer fish.
Affiliations and expertise
Marine Biological Station, Sado Island Center for Ecological Sustainability, Niigata University, Japan
KT
Kazuyoshi Tsutsui
Affiliations and expertise
Laboratory of Integrative Brain Sciences, Department of Biology, Waseda University, Center for Medical Life Science of Waseda University, Japan