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Guide to Techniques in Mouse Development, Part B

Mouse Molecular Genetics

  • 1st Edition - August 24, 2010
  • Editors: Paul Wassarman, Philippe M. Soriano
  • Language: English
  • Paperback ISBN:
    9 7 8 - 0 - 1 2 - 3 8 4 8 8 2 - 6

Guide to Techniques in Mouse Development, Part B, is an authoritative guide to different methods used in enzymology, focusing on investigating mouse development using technolog… Read more

Guide to Techniques in Mouse Development, Part B

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Guide to Techniques in Mouse Development, Part B, is an authoritative guide to different methods used in enzymology, focusing on investigating mouse development using technological advances. The text provides information regarding the principles of the methods in mouse development, and it offers readers reliable experimental protocols and recipes described comprehensively by leaders in the field of enzymology.

The text is divided into three sections and organized into 25 chapters. Below are several concepts covered by the text:

Lentivirus transgenesis o Germline modification using mouse stem cells

Electroporation

Applications of transposons in mouse genetics

Functional genomics using transposon systems

The use of DNA transposons in detecting cancer genes in mice

Recombination, conditional mutagenesis and induction of tamoxifen

Genetic fate mapping using recombinases

Genetic screens mouse ES cells

Gene trap mutagenesis

Mouse mutagenesis

Self- renewal and pluripotency

Transgenic RNAi applications

Gene knockdowns

Tetracycline-controlled transcription

Gene expression profiling of mouse embryos

The book is a comprehensive guide for students and professionals in genetics, cytology and molecular biology, who will find this book invaluable for their learning and practice.