
Gold Nanoparticles, Nanomaterials and Nanocomposites
Science, Technology and Applications
- 1st Edition - November 30, 2024
- Imprint: Elsevier
- Editors: S. K. Khadheer Pasha, Kalim Deshmukh, Chaudhery Mustansar Hussain
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 5 8 9 7 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 2 7 0 - 4
Gold Nanoparticles, Nanomaterials and Nanocomposites: Science, Technology and Applications provides a comprehensive review of recent research developments in the synthesis… Read more

Purchase options

Institutional subscription on ScienceDirect
Request a sales quoteGold Nanoparticles, Nanomaterials and Nanocomposites: Science, Technology and Applications provides a comprehensive review of recent research developments in the synthesis, processing, functionalization, characterization, and properties of gold nanoparticles (Au NPs) for a broad range of different applications. Emphasis is placed on the fundamental chemistry, different synthesis approaches, strategies for stabilization and control of shape size and morphology, surface chemistry and physicochemical characteristics, as well as surface functionalization and applications of Au NPs. The book also covers important topics such as biocompatibility, biodegradability, cytotoxicity and the health and environmental impact of Au NPs.
The book will be a valuable reference resource for academic and industrial researchers working in the fields of materials science and engineering, nanomaterials, polymer composites, and biomedical engineering.
- Covers current and emerging research trends in the synthesis, processing, functionalization, characterization, and performance of gold nanoparticles (Au NPs)
- Includes comprehensive coverage of a broad range of applications such as sensing and biosensing, electronic devices, electro and photocatalysis, solar cells, supercapacitors, point of care diagnostic tools and devices, drug delivery and controlled drug release, antimicrobial, antifungal and antiviral applications, cancer diagnostics and therapy, tissue engineering, bioimaging, as well as for bioremediation and pharmaceutical applications
- Contains contributions from leading researchers across the globe from academic, industrial, government, and private research institutions
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter 1. Multifunctional gold nanoparticles: Past, present, and future
- 1 Introduction
- 2 Synthesis procedures of AuNPs
- 2.1 Physical approach
- 2.2 Chemical approach
- 2.2.1 Turkevich method
- 2.2.2 Brust-Schiffrin method
- 2.3 Electrochemical method
- 2.4 Seeding growth method
- 2.5 Biological method
- 2.6 Ionic liquids and AuNPs
- 2.7 Sonochemical method
- 3 Characterization of multifunctional AuNPs
- 3.1 UV-visible spectroscopic studies
- 3.2 Fourier transform infrared spectroscopy (FTIR)
- 3.3 X-ray diffraction analysis (XRD)
- 3.4 Energy dispersive X-ray diffraction analysis (EDX)
- 4 Multifunctional roles of AuNPs
- 5 Applications of multifunctional AuNPs
- 5.1 AuNPs as vaccines
- 5.1.1 Protein/peptide-modified AuNPs as vaccines
- 5.1.2 Carbohydrate-modified AuNPs as vaccines
- 5.1.3 DNA-modified AuNPs as vaccines
- 5.2 AuNP-enabled diagnosis
- 5.3 AuNP-enabled treatment
- 5.3.1 Antibiotics using AuNPs modified with small molecules
- 5.3.2 Functionalized AuNPs for cancer therapy
- 5.4 Medical applications of multifunctional AuNPs
- 5.4.1 Delivery carriers
- 5.4.2 Therapeutics
- 5.4.3 Diagnostics
- 5.4.4 Imaging
- 5.4.5 AuNPs as a safe cosmetic ingredient
- 6 Pharmacological activities of AuNPs
- 6.1 Antimicrobial agents
- 6.2 Antioxidant agents
- 6.3 Antiinflammatory agents
- 6.4 Anticancer agents
- 6.5 Retinopathy
- 6.6 Neuroprotective effects: Alzheimer's disease and Parkinson's disease
- 6.7 Skin disorders
- 6.8 Inflammatory bowel disease (IBD)
- 6.9 Bone cartilage disorder
- 6.10 Cancer treatment
- 6.11 Metabolic syndrome and others
- 7 Agricultural aspects of AuNPs
- 8 Environmental aspects of AuNPs
- 9 AuNPs in the past
- 10 Present and future perspectives of AuNPs
- 10.1 Current challenges in AuNPs based nanomedicine
- 11 Conclusions
- Chapter 2. Synthesis of gold nanoparticles using physical and chemical methods: Strategies for stabilization, controlling shape, size and morphology
- 1 Introduction
- 2 Properties of GNPs
- 3 General method of synthesis for GNPs and their characterization
- 3.1 Synthesis of GNPs
- 3.1.1 Physical synthesis method
- 3.1.2 Chemical method
- 3.1.3 Biological synthesis
- 4 Several other synthesis methods for GNPs
- 5 Stabilization of GNPs
- 5.1 Electrostatic stabilization
- 5.2 Steric stabilization
- 5.3 Electro steric stabilization of GNPs
- 6 Theranostics of GNPs
- 6.1 Near-infrared fluorescence (NIR) imaging for GNPs
- 6.2 Tumor microenvironment in vivo photoacoustic imaging with pH-responsive targeted GNPs
- 6.3 Photodynamic therapy based GNPs
- 7 Toxicity of GNPs
- 7.1 In vivo toxicity studies of GNPs
- 7.1.1 In vitro toxicity studies of GNPs
- 8 Limitations of GNPs
- 9 Conclusion and outlook
- Chapter 3. Green chemistry mediated and biogenic synthesis of gold nanoparticles: Prospects and challenges
- 1 Introduction
- 2 Green synthesis of AuNPs
- 3 Factors affecting the synthesis of AuNPs
- 3.1 Temperature
- 3.2 Bio-reducing agent
- 3.3 Reaction time
- 3.4 pH
- 4 Synthesis of AuNPs using plant extracts
- 4.1 Proposed mechanism
- 5 Synthesis of AuNPs using microbes
- 5.1 Bacteria
- 5.2 Actinobacteria
- 5.3 Fungi
- 5.4 Algae
- 5.5 Mechanism of microbe-mediated synthesis of AuNPs
- 6 Comparing AuNPs produced by plants and microorganisms
- 7 Prospects and challenges
- 8 Conclusions
- Chapter 4. Surface chemistry and physiological characteristics of gold nanoparticles
- 1 Introduction
- 2 Surface chemistry of AuNPs
- 2.1 Significance of surface chemistry
- 3 Role of surface charge of nanomaterials
- 4 Functionalization of AuNPs
- 4.1 Functionalization of citrate-capped AuNPs
- 4.2 Functionalization of sodium borohydride reduced AuNPs
- 4.3 Principle reactions of surface modification
- 4.4 Reasons for surface functionalization of AuNPs
- 5 Surface stabilizing ligands/capping agents
- 5.1 Nature of surface stabilizing ligand
- 5.2 Criteria for the selection of surface stabilizing ligand
- 5.3 Capping agents for functionalization
- 5.3.1 Polyethylene glycol (PEG)
- 5.3.2 Polyvinylpyrrolidone (PVP)
- 5.3.3 Polyvinyl alcohol (PVA)
- 5.3.4 Bovine serum albumin (BSA)
- 5.3.5 Ethylene diamine tetra acetic acid (EDTA)
- 5.3.6 Chitosan
- 6 Physicochemical properties of AuNPs
- 7 Applications of functionalized AuNPs
- 7.1 AuNPs in therapy
- 7.1.1 Photothermal therapy
- 7.1.2 Photodynamic therapy
- 7.1.3 Radiotherapy
- 7.1.4 Prophylactics
- 7.2 Role of AuNPs in sensing
- 7.2.1 Colorimetric sensing
- 7.2.2 Surface plasmon resonance sensing
- 7.2.3 Fluorescence sensing
- 7.2.4 Electrochemical sensing
- 7.3 Role of AuNPs in delivery
- 7.4 Role of AuNPs in catalysis
- 7.5 Role of AuNPs in biological activity
- 8 Conclusion and future perspective
- Chapter 5. Functionalization and surface modification techniques of gold nanoparticles and their influence on the physical, chemical, and biological properties
- 1 Introduction
- 2 Synthesis methods for the preparation of gold nanoparticles
- 3 Biomedical function of gold nanoparticles
- 4 Functionalization and surface modification of gold nanoparticles
- 4.1 Thiol-based chemistry
- 4.2 Click chemistry
- 4.3 Bioconjugation
- 4.4 Encapsulation
- 4.5 Ligand exchange
- 4.6 Electrostatic adsorption
- 4.7 Layer-by-layer assembly
- 5 Influence on physical properties
- 6 Influence on chemical properties
- 7 Influence on biological properties
- 8 Application of functionalized gold nanoparticles
- 9 Future prospects and challenges
- 10 Conclusions
- Chapter 6. Spectroscopic and microscopic characterizations of gold nanoparticles
- 1 Introduction
- 2 Spectroscopic techniques for the characterization of gold nanoparticles
- 2.1 Dynamic light scattering (DLS)
- 2.2 Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF)
- 2.3 Fourier transform infrared spectroscopy (FT-IR)
- 2.4 UV-Visible spectroscopy
- 2.5 X-ray diffraction (XRD)
- 2.6 Nuclear magnetic resonance spectroscopy (NMR)
- 2.7 Fluorescence spectroscopy
- 2.8 X-ray photoelectron spectroscopy (XPS)
- 2.9 Raman spectroscopy
- 3 Microscopic techniques for the characterization of gold nanoparticles
- 3.1 Electron microscopy
- 3.1.1 Scanning electron microscopy (SEM)
- 3.1.2 Transmission electron microscopy (TEM)
- 3.2 Scanning probe microscopy (SPM)
- 3.2.1 Atomic force microscopy (AFM)
- 4 Conclusion
- Chapter 7. Core-shell structured gold nanoparticles: From synthesis to applications
- 1 Introduction
- 1.1 Advantages of core-shell over regular nanoparticles
- 2 Classification
- 2.1 Inorganic@inorganic CSNPs (Au@SiO2, Au@Fe3O4)
- 2.1.1 Inorganic@inorganic (silica) CSNPs
- 2.1.2 Inorganic@inorganic (nonsilica) CSNPs
- 2.2 Inorganic@organic CSNPs
- 2.2.1 Magnetic@organic CSNPs
- 2.2.2 Nonmagnetic@organic CSNPs
- 2.2.3 Metal@organic CSNPs
- 2.3 Organic@organic CSNPs
- 3 Shapes of CSNPs
- 4 Synthesis of CSNPs
- 4.1 Sol-gel (SG) method
- 4.2 Deposition method
- 4.3 Solvothermal method
- 4.4 Reduction method
- 4.5 Science behind the selection of core and shell: Compatibility issues
- 5 Mechanism of CSNP synthesis
- 5.1 Synthesis of inorganic CSNPs
- 5.1.1 Metal nanoparticles synthesis
- 5.1.2 Synthesis of metal and metalloid CSNPs
- 5.1.3 Synthesis of metal salt and metal chalcogenide CSNPs
- 5.2 Synthesis of metal-organic CSNPs
- 5.2.1 Addition polymerization
- 5.2.2 Step-polymerization
- 6 Characterization of CSNPs
- 6.1 Microscopic techniques
- 6.1.1 Scanning electron microscopy (SEM)
- 6.1.2 Transmission electron microscopy (TEM)
- 6.1.3 Atomic force microscopy (AFM)
- 6.2 Spectroscopic techniques
- 6.2.1 UV–vis spectroscopy
- 6.2.2 Fluorescence or photoluminescence (PL) spectroscopy
- 6.2.3 X-ray photoelectron spectroscopy (XPS)
- 6.2.4 Energy-dispersive X-ray spectroscopy (EDX)
- 6.2.5 Inductively coupled plasma-mass spectrometry (ICP-MS)
- 6.2.6 Surface-enhanced Raman signal (SERS)
- 6.3 Scattering techniques
- 6.3.1 Dynamic light scattering (DLS)
- 6.3.2 X-ray diffraction (XRD)
- 6.3.3 Small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS)
- 6.3.4 Small-angle neutron scattering (SANS)
- 7 Applications
- 7.1 Catalysis
- 7.1.1 Hydrogenation reaction
- 7.1.2 Oxidation reaction
- 7.1.3 Coupling reactions
- 7.1.4 Ammonia decomposition reaction
- 7.1.5 Tandem deprotection-Knoevenagel reaction and Henry reaction
- 7.2 Drug delivery and targeting
- 7.3 Cell labeling and bioimaging
- 7.4 Energy and environment
- 8 Challenges of CSNPs
- 9 Conclusion and future directions
- Chapter 8. Polymer nanocomposites based on gold nanoparticles: Synthesis, properties and applications
- 1 Introduction
- 2 Synthesis and characterization of AuNPs and polymer composites
- 2.1 Surface modifications
- 2.1.1 Ligand exchange
- 2.1.2 Layer-by-layer deposition
- 2.2 Synthesis of AuNPs and synthetic polymer composites
- 2.3 Synthesis of AuNPs and polysaccharide composites
- 2.4 Synthesis of AuNPs and conducting polymer composites
- 2.5 Main techniques for the characterization of polymer and AuNPs composites
- 2.5.1 Electron microscopy
- 2.5.2 Dynamic light scattering
- 2.5.3 Zeta potential
- 2.5.4 Small angle X-ray scattering (SAXS)
- 2.5.5 UV-vis spectroscopy
- 2.5.6 Fluorescence and vibrational spectroscopies
- 3 Properties and applications of AuNPs and polymer composites
- 3.1 Optical properties
- 3.1.1 Catalytic degradation
- 3.1.2 Optical sensor
- 3.2 Electrochemical properties
- 3.2.1 Electrochemical sensors and biosensors
- 3.2.2 Energy storage
- 3.2.3 Other electrochemical applications
- 3.3 Biocompatibility
- 3.3.1 Controlled release
- 3.3.2 Tissue engineering
- 4 Challenges and future perspectives
- 5 Conclusion
- Chapter 9. Gold nanoparticles for surface-enhanced Raman scattering
- 1 Introduction
- 1.1 Light-matter interaction
- 1.2 Raman scattering
- 1.3 Surface-enhanced Raman scattering (SERS)
- 2 Sensing applications
- 2.1 Micromolecule mediated sensing
- 2.1.1 Sensing of thiram and chloramphenicol
- 2.1.2 Sensing of melamine
- 2.1.3 Sensing of Hg and Pb
- 2.1.4 Selective sensing of 2,5-dimercapto-1,3,4-thiadiazole (DMTD) conformers
- 2.1.5 Sensing of thioflavin T (ThT)
- 2.1.6 Sensing of selenourea (SeU)
- 2.1.7 Sensing of explosives
- 2.2 Macromolecule mediated sensing
- 2.2.1 Sensing of pesticide
- 2.2.2 Sensing of bisphenol-A
- 2.2.3 Sensing of crystal violet
- 2.2.4 Sensing of Salmonella typhimurium
- 2.3 Surface catalysis
- 2.3.1 Surface mediated dimerization of thiazoline thiol (TT)
- 2.3.2 Surface catalyzed reduction of para-nitrothiophenol
- 2.4 Diagnostic applications
- 2.4.1 Pathological diagnosis
- 2.4.2 Point of care (POC) diagnosis
- 3 Conclusion and future directions
- Chapter 10. Gold nanoparticles for sensing and biosensing applications
- 1 Introduction
- 2 Synthesis of AuNPs
- 3 Characterization of AuNPs
- 3.1 Morphology types and advantages of AuNPs
- 4 Colorimetric sensing based on AuNPs
- 5 Fluorescence sensing based on AuNPs
- 6 Lateral flow biosensors based on AuNPs
- 7 Surface plasmon resonance sensing based on AuNPs
- 8 Electrical and electrochemical sensing on AuNPs
- 8.1 The role of AuNPs in electrochemical biosensing
- 8.2 Recent AuNPs based electrochemical biosensor applications
- 9 Biosensing/signal amplification strategies
- 10 Current challenges
- 11 Conclusions and future perspectives
- Chapter 11. Gold nanoparticles in electronic and photonic applications
- 1 Introduction
- 2 Overview of gold nanoparticles
- 3 Fabrication of gold nanoparticles
- 3.1 Top-down approach
- 3.2 Bottom-up approach
- 3.3 Physical and chemical methods
- 3.4 Biological (green) fabrication of gold nanoparticles
- 4 Modification and characterization of gold nanoparticles
- 5 Applications of gold nanoparticles
- 5.1 Photonic applications
- 5.2 Electronic applications
- 6 Conclusion
- Chapter 12. Gold nanoparticles for catalytic and photocatalytic applications
- 1 Introduction
- 2 Gold nanoparticles
- 3 Synthesis of various types of Au nanoparticles
- 3.1 Au nanospheres
- 3.2 Au nanorods
- 3.3 Au nanoshells
- 3.4 Au nanocages
- 4 Properties of gold nanoparticles
- 4.1 Physical properties
- 4.2 Chemical properties and catalysis
- 4.3 Optical properties
- 5 Applications of gold nanoparticles
- 5.1 Gold nanoparticles for catalytic applications
- 5.2 Gold nanoparticles for photocatalytic application
- 6 Future prospects and challenges
- 7 Conclusions
- Chapter 13. Gold nanoparticles for solar cells applications
- 1 Introduction
- 2 Solar cells design
- 3 Solar cells structure
- 4 Types of solar cells
- 4.1 First-generation solar cells
- 4.1.1 Single/mono-crystalline silicon solar cells
- 4.1.2 Polycrystalline silicon solar cells (Poly-Si or mc-Si)
- 4.2 Second-generation solar cells
- 4.2.1 Amorphous silicon thin film solar cells
- 4.2.2 Cadmium telluride thin film solar cells
- 4.2.3 Copper indium gallium di-selenide solar cells
- 4.3 Third-generation solar cells
- 4.3.1 DSSCs
- 4.3.2 Polymer solar cells
- 4.3.3 Perovskite solar cells
- 5 Plasmonic effect of gold nanoparticles
- 6 Solar energy applications
- 6.1 Examples of solar energy production in solar devices
- 6.2 Solar energy for organic pollutants degradation
- 6.3 Solar energy for water splitting
- 6.4 Solar energy for photothermal conversion
- 7 Future plans for efficient solar cells based on active gold nanoparticles
- 8 Conclusion
- Chapter 14. Gold nanoparticles for batteries and supercapacitors
- 1 Introduction
- 2 Gold nanoparticle-based materials for battery application
- 2.1 Gold nanoparticle-carbon based materials for battery application
- 2.2 Gold nanoparticle-metal oxides for battery application
- 2.3 Gold nanoparticle-conducting polymers for battery application
- 2.4 Other gold nanoparticle materials for battery application
- 3 Gold nanoparticle-based materials for supercapacitor application
- 3.1 Gold nanoparticle-carbon based materials for supercapacitor application
- 3.2 Gold nanoparticle-metal oxides for supercapacitor application
- 3.3 Gold nanoparticle-conducting polymers for supercapacitor application
- 3.4 Other gold nanoparticle materials for supercapacitor application
- 4 Challenges and future perspectives
- 5 Summary and conclusion
- Chapter 15. Gold nanoparticles for antimicrobial, antifungal, and antiviral applications
- 1 Introduction
- 2 Methods of synthesis of gold NPS
- 2.1 Physical methods of synthesis of gold NPs
- 2.1.1 Gamma radiation method
- 2.1.2 UV radiation method
- 2.1.3 Microwave-assisted method
- 2.2 Chemical methods of synthesis of gold NPs
- 2.2.1 Turkevich method
- 2.2.2 Brust – Schiffrin method
- 2.2.3 Schmid's cluster method and phosphorous as ligand
- 2.3 Biological method of synthesis of gold NPs
- 3 Mechanism of action of gold NPS as antimicrobial agent
- 3.1 Mechanism of antibacterial activity of gold NPs
- 3.2 Mechanism of antifungal activity of gold NPs
- 3.3 Mechanism of antiviral activity of gold NPs
- 4 Reports of antimicrobial, antifungal, and antiviral activity of gold NPS
- 4.1 Gold NPs as antibacterial agent
- 4.2 Gold NPs as antifungal agents
- 4.3 Gold NPs as antiviral agent
- 5 Surface modification of gold nanoparticles and antimicrobial activity
- 6 Conclusion and future prospectives
- Chapter 16. Gold nanoparticles for cancer diagnosis and therapy
- 1 Introduction
- 2 AuNP synthesis and characterization
- 2.1 Different methods of AuNP synthesis
- 2.2 Various methods of AuNP characterization
- 2.2.1 Scanning electron microscopy
- 2.2.2 Transmission electron microscopy
- 2.2.3 Laser ablation and induced coupled plasma mass spectrometry
- 3 AuNPs in cancer treatment
- 3.1 Photothermal therapy
- 3.2 Radiotherapy
- 3.3 Gene therapy
- 3.4 Immunotherapy
- 4 AuNPs in cancer diagnosis
- 4.1 Shape and functionalization of AuNPs for cancer diagnosis
- 4.2 Magnetic resonance imaging
- 4.3 Photoacoustic imaging
- 4.4 X-ray scatter imaging
- 5 Challenge and future perspective
- 6 Conclusion
- Chapter 17. Gold nanoparticles for photothermal and photodynamic therapy
- 1 Introduction
- 2 Photothermal therapy
- 2.1 Mechanism of PTT
- 2.1.1 Laser tissue interaction and heat generation
- 2.1.2 PTT with the assistant of nanoagent
- 2.2 Thermophysical and optical properties of GNAs
- 2.3 Strategies for improving GNAs mediated PTT
- 2.4 Applications of GNAs for photothermal therapy
- 2.4.1 Enhancing cancer treatment through PTT with GNRs
- 2.4.2 Enhancing cancer treatment through PTT with GNSps and GNShs
- 2.4.3 Enhancing cancer treatment through PTT with other shape of GNAs
- 2.4.4 Enhancing PTT based therapeutic efficiency with GNAs through pulse laser irradiation
- 3 Photodynamic therapy (PDT)
- 3.1 Mechanism of PDT
- 3.2 Photosensitizers (PSs) used in PDT
- 3.2.1 First generation PSs
- 3.2.2 Second generation PSs
- 3.2.3 Third generation PSs
- 3.3 Gold nanoagents based PDT
- 3.4 Applications of gold nanoagents for PDT
- 4 Combinational therapy
- 4.1 Applications of gold nanoagents for combinational therapy
- 5 Toxicity and biocompatibility of GNPs
- 6 Conclusions: Critical remarks and revolutionizing clinical therapies of gold nanomedicine
- Chapter 18. Gold nanoparticles in nanomedicine: Advances, prospects, and challenges
- 1 Introduction
- 2 Advances in the use of gold nanoparticles
- 2.1 Delivery of drugs and prodrugs
- 2.2 Gene delivery
- 2.3 Diagnostics and imaging
- 2.3.1 Spectroscopy-based diagnosis
- 2.3.2 Fluorescence-based diagnosis
- 2.3.3 Raman scattering and surface-enhanced
- 2.3.4 Photoacoustic imaging
- 2.4 Photothermal and photodynamic therapy
- 2.5 Biosensors
- 3 Challenges in the use of gold nanoparticles in nanomedicine
- 3.1 Toxicity and biocompatibility
- 3.2 Administration and synthesis challenges
- 3.3 Regulatory concerns
- 4 Conclusion and future prospects
- Chapter 19. Gold nanoparticles for tissue engineering applications
- 1 Introduction
- 2 Synthesis, modification, and properties
- 3 Diagnostic and therapeutic applications
- 3.1 Medical imaging
- 3.1.1 Optical imaging
- 3.1.2 Photoacoustic imaging
- 3.1.3 Magnetic resonance imaging
- 3.2 Delivery systems
- 3.3 Photothermal therapy
- 3.3.1 Gold nanostars
- 3.3.2 Gold nanoshells
- 3.3.3 Gold nanospheres
- 3.3.4 Gold nanorods
- 3.3.5 Gold nanocages
- 3.4 Stem cell differentiation
- 3.5 Gold nanoparticles-integrated scaffolds
- 3.5.1 Mechanical properties
- 3.5.2 Conductivity
- 3.5.3 Enhanced biological activity
- 4 Challenges and outlooks
- 5 Conclusion
- Chapter 20. Antineoplastic properties of biosynthesized gold nanomaterials: A new sustainable paradigm for cancer therapeutics
- 1 Cancer: overview, causes, treatments, and types
- 1.1 Cancer overview
- 1.2 General categories of cancers
- 1.3 Metastatic cancers
- 1.4 General categories of cancers
- 2 Causes of cancer
- 2.1 Cancer risk factors
- 3 Cancer treatment
- 3.1 Cancer treatment terms
- 3.2 Types of cancer
- 4 Nanotechnology and nanoscience: An overview
- 4.1 Gold nanoparticles: Unique properties and pharmaceutical potentials
- 5 Biosynthesis of gold nanoparticles: An overview
- 5.1 Phytosynthesis of gold nanoparticles
- 5.2 Mycosynthesis of gold nanoparticles
- 5.3 Bacteriogenic synthesis of gold nanoparticles
- 5.4 Phycosynthesis of gold nanoparticles
- 6 Antineoplastic properties of bioengineered gold nanoparticles
- 7 Anticancer drug delivery systems based on bioengineered gold nanoparticles
- 8 Conclusions and future outlook
- Chapter 21. Gold nanoparticles for bio-imaging applications
- 1 Introduction
- 2 Dark-field microscopy
- 3 Differential interference contrast microscopy
- 4 Interferometric scattering microscopy
- 5 Surface-enhanced Raman scattering (SERS)
- 6 Plasmon-enhanced fluorescence (PEF)
- 7 Photoacoustic imaging
- 8 Optical coherence tomography
- 9 Multiphoton imaging
- 10 Conclusion and future perspectives
- Chapter 22. Computational modeling and molecular dynamic simulations of gold nanoparticles
- 1 Introduction
- 2 Nanoinformatics databases
- 2.1 NBIK (nanomaterial biological interactions knowledgebase)
- 2.2 InterNano
- 2.3 Nano-HUB database
- 2.4 National Center for Biomedical Ontology Bioportal
- 2.5 ISA-TAB-nano
- 2.6 caNanoLab
- 2.7 Nanotechnology characterization laboratory
- 2.8 eNanoMappera
- 2.9 Nanowerk
- 2.10 PubVINAS
- 3 Tools for molecular modeling of gold nanoparticles
- 3.1 NanoModeler (https://www.nanomodeler.it/)
- 3.2 NanoCrystal
- 3.3 PBPK modeling software
- 3.4 CHARMM-GUI
- 4 DOCKING of gold nano particles
- 4.1 rDock package
- 4.2 PatchDock webserver
- 4.3 AutoDock
- 4.4 Hex 8.0.0 software
- 5 Molecular dynamics simulations
- 5.1 LAMMPS
- 5.2 AMBER
- 5.3 NAMD
- 5.4 OpenMD
- 5.5 Geant4-DNA
- 5.6 GROMACS (groningen MAchine for chemical simulations)
- 6 Conclusion
- Chapter 23. Sustainability, biocompatibility, biodegradability, cytotoxicity, environmental and health impact of gold nanoparticles
- 1 Introduction
- 2 Synthesis and characterization of gold nanoparticles
- 2.1 Chemical and physical methods
- 2.2 Biogenic synthesis
- 3 Sustainability and biodegradability of gold nanoparticles
- 4 Health impact of gold nanoparticles related to biocompatibility and cytotoxicity
- 4.1 Factors that influence the toxicity and biocompatibility of AuNPs
- 4.2 Therapeutic use x toxicity to AuNPs
- 4.3 Immunotoxicity
- 4.4 Cytotoxicity and antitumor activity
- 4.5 Antimicrobial activity
- 5 Environmental impact of gold nanoparticles
- 6 Conclusions and future perspectives
- Index
- Edition: 1
- Published: November 30, 2024
- Imprint: Elsevier
- No. of pages: 750
- Language: English
- Paperback ISBN: 9780443158971
- eBook ISBN: 9780443132704
SP
S. K. Khadheer Pasha
KD
Kalim Deshmukh
CM
Chaudhery Mustansar Hussain
Dr. Chaudhery Mustansar Hussain, PhD, is an Adjunct Professor and Director of Laboratories in the Department of Chemistry & Environmental Sciences at the New Jersey Institute of Technology (NJIT), Newark, New Jersey, United States. His research is focused on the applications of nanotechnology and advanced materials, environmental management, analytical chemistry, and other various industries. Dr. Hussain is the author of numerous papers in peer-reviewed journals as well as a prolific author and editor of around One hundred and fifty (150) books, including scientific monographs and handbooks in his research areas. He has published with ELSEVIER, American Chemical Society, Royal Society of Chemistry, John Wiley & Sons, CRC Press, and Springer.