Fused Pyranones
Multifaceted Building Blocks for Molecular Diversity
- 1st Edition - June 17, 2024
- Authors: Vishnu Ji Ram, Ramendra Pratap, Pratik Yadav
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 2 1 7 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 3 2 1 3 - 2
Fused Pyranones: Multifaceted Building Blocks for Molecular Diversity covers the synthesis and chemical reactivity of fused pyranone ring systems, such as coumarin, isocou… Read more
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Request a sales quote- Includes various synthetic methodologies for generating molecular diversity
- Covers natural and synthetic products with benzopyranone ring systems, which are used for the treatment of diseases such as cancer, diabetes, ulcers, allergies, asthma, fungal, and bacterial infections, and more
- Discusses applications of these new chemical entities in the fields of drug discovery, food supplements, perfumery, preparation of new organic catalysts, and materials
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Author biographies
- Chapter 1 Fused pyrones: Multifaceted building blocks for molecular diversity
- Abstract
- 1.1 Introduction
- References
- Chapter 2 Characteristics of coumarins and fused coumarins
- Abstract
- References
- Chapter 3 Chemistry of natural and synthetic 2H-1-benzopyran-2-ones (coumarins)
- Abstract
- 3.1 Introduction
- 3.2 Chemistry of natural and synthetic coumarins
- References
- Chapter 4 Chemistry of 1H-2-benzopyran-1-one (isocoumarin)
- Abstract
- 4.1 Natural benzo[g]isocoumarins
- 4.2 Dimeric benzo[g]isocoumarins
- 4.3 Synthesis of isocoumarins
- 4.4 Chemical reactivity
- References
- Chapter 5 Chemistry of 4H-1-benzopyran-4-ones (chromones, or 4H-chromene-4-ones)
- Abstract
- 5.1 Natural chromone alkaloids
- 5.2 Natural fused chromones
- 5.3 Synthetic furano[3,2-g]chromones
- 5.4 Synthesis of 3-(4-methoxyphenyl)-8-(4-nitrobenzoyl)-4H-furo[2,3-h]chromone
- 5.5 Synthesis of chromones, annulated with 5-membered heterocycles
- 5.6 Synthesis of pyrano[2,3-h]chromones
- 5.7 Synthesis of chromones
- References
- Chapter 6 Chemistry of partially reduced coumarins and chromones
- Abstract
- 6.1 Chemistry of 3,4-dihdro-2H-1-benzpyran-2-ones (3,4-dihydrocoumarins)
- 6.2 Chemistry of 2,3-dihydro 4H-1-benzopyran-4-ones (chroman-4-ones)
- References
- Chapter 7 Synthesis and chemical reactivity of xanthones
- Abstract
- 7.1 Introduction
- 7.2 Naturally occurring xanthones
- 7.3 Medicinal properties of xanthone-based compounds
- 7.4 Biosynthesis of xanthone
- 7.5 Synthetic strategies
- 7.6 Reactivity
- 7.7 Conclusion
- References
- Chapter 8 Chemistry of benzo fused chromenones and partially reduced benzo fused chromenones
- Abstract
- Section A: Chemistry of benzo fused chromenones
- Section B: Chemistry of partially reduced benzo fused chromenones
- Chapter 9 Miscellaneous fused pyranone systems
- Abstract
- 9.1 2H,5H-Thiochromeno[4,3-b]pyran-2-ones
- 9.2 5,6-Dihydro-2H-benzo[b]pyrano[2,3-d]oxepin-2-one
- 9.3 5,6-Dihydro-2H-naphtho[2,3-b]pyrano[2,3-d]oxepin-2-one
- 9.4 8H-Acenaphtho[1,2-b]pyran-8-one
- 9.5 Pyrano[3,4-c]pyran-1,8-dione
- 9.6 6,7-Dihdrobenzo[6,7]cyclohepta[1,2-b]pyran-2(5H)-one
- References
- Chapter 10 Importance of fused-pyranones in medicine and material science
- Abstract
- 10.1 Medicinal importance of fused-pyranones
- 10.2 Application of fused pyranones in material science
- References
- Index
- No. of pages: 620
- Language: English
- Edition: 1
- Published: June 17, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780128212172
- eBook ISBN: 9780128232132
VJ
Vishnu Ji Ram
RP
Ramendra Pratap
Prof. Ramendra Pratap completed his master’s from the University of Gorakhpur in 2001 and then he moved to Central Drug Research Institute, Lucknow for doctoral research. He worked with Dr. Vishnu Ji Ram for four and a half years on ring transformation reactions of 2H-pyran-2-ones. He worked on nucleoside modification chemistry as a postdoctoral fellow at the City University of New York, USA, for two years. He received a renowned Humboldt fellowship and shifted to the University of Saarland, Germany. In Saarbrucken, he was involved in Mo-catalyzed reactions. In September 2010, He joined the Department of Chemistry, University of Delhi as an Assistant Professor. Currently, He is working as a full Professor. Till now he has published more than 100 research papers in various international Journals. He also received JSPS invitation fellowship during the year 2016-17. His chemistry focuses on developing various heterocycles, carbocycles, materials, and metal-catalyzed bond formation reactions. His major research contribution involves use of isolated and fused pyranones to establish new molecular entities.
PY
Pratik Yadav
Dr. Pratik Yadav has completed his B.Sc. (Hons.) Chemistry from Hansraj College, University of Delhi. He earned his master’s and Ph.D. in Chemistry with organic chemistry specialization from the Department of Chemistry, University of Delhi. In his PhD, he worked on the synthesis of aromatic and heteroaromatic scaffolds using ketene dithioacetals and 2-pyranones under the supervision of Prof. Ramendra Pratap. He was awarded DAAD fellowship by DAAD, Bonn in 2015 to work in the area of decarboxylative cross-coupling and C-H activation reaction at Technical University Kaiserslautern, Germany in the research group of Prof. Dr. Lukas J. Goossen. He worked as an assistant professor in the Department of Chemistry, Kirori Mal College, University of Delhi from 2017-2021. Currently, He is working as a postdoctoral research fellow at Long Island University, Brooklyn, USA in the area of design and synthesis of Boron-based small molecular probes and therapeutics (including kinase inhibitors and synthetic retinoids). His research involves modern and catalytic functionalization methods to synthesize small drug like molecules and their chemical biology. Until now, he has published more than 20 research papers in various international Journals.