Fundamentals of Sensor Technology

Principles and Novel Designs

1st Edition - May 5, 2023
Imprint: Woodhead Publishing
Editors: Ahmed Barhoum, Zeynep Altintas
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 4 3 1 - 0
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 4 3 2 - 7

Fundamentals of Sensor Technology: Principles and Novel Designs presents an important reference on the materials, platforms, characterization and fabrication methods used in the de… Read more

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Fundamentals of Sensor Technology: Principles and Novel Designs presents an important reference on the materials, platforms, characterization and fabrication methods used in the development of chemical sensor technologies. Sections provide the historical context of sensor technology development, review principles for the design of sensing devices and circuits, delve into the most common chemical and biological sensor types, cover unique properties and performance requirements, discuss fabrication techniques, including defining critical parameters, modeling and simulation strategies, and present important materials categories used in sensing applications, such as nanomaterials, quantum dots, magnetic materials, and more.This book is appropriate for the interdisciplinary community of researchers and practitioners interested in the development of sensor technologies, including materials scientists and engineers, analytical chemists and other related disciplines.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Editor biographies
Preface
Part One. Sensing principles and basic design
1. Historical development of sensing technology
1.1. Introduction
1.2. Historical background of biosensors
1.3. Evolution of detection mechanisms
1.4. Receptor types, selection, and immobilization
1.5. Commercialization for sensing applications
1.6. Conclusion and remarks
2. Sensor principles and basic designs
2.1. Introduction
2.2. Transduction techniques for chemical sensors
2.3. Conclusions and remarks
3. Fundamentals of biological recognition elements
3.1. Introduction
3.2. Biorecognition receptors for biosensor technology
3.3. Conclusion and future prospects
Part Two. Sensing techniques
4. Lab-on-a-chip sensors: recent trends and future applications
4.1. Introduction to lab-on-a-chip technology
4.2. Development of LOC sensors
4.3. Applications of LOC sensors
4.4. Novel LOC sensor technologies and miniaturization
4.5. Commercial LOC technologies
4.6. Conclusion and future remarks
5. Potentiometric sensors
5.1. Introduction
5.2. Principles of potentiometric sensors
5.3. The main types of potentiometric sensors
5.4. Applications of potentiometric sensors
5.5. Recent and future trends
5.6. Conclusions
6. Amperometric sensors
6.1. Introduction
6.2. Principle of amperometric sensors
6.3. Amperometric sensors design
6.4. Applications of amperometric sensors
6.5. Multiplex and integrated amperometric sensing platforms
6.6. Conclusion and remarks
7. Fluorescent sensors
7.1. Introduction
7.2. The mechanisms of photoluminescence
7.3. Meet the fluorophore family
7.4. Future directions of fluorescent-based sensors
8. Surface plasmon resonance sensors
8.1. Introduction
8.2. Imaging SPR
8.3. Plasmon, coupler, and the resonance in SPR sensors
8.4. Analytical performance of SPR sensors
8.5. Utilization of the SPR
8.6. Surface functionalization in SPR sensors
8.7. SPR-based biosensing approaches and their applications
8.8. Conclusion
9. Ellipsometric biosensors
List of abbreviations
9.1. Introduction
9.2. History
9.3. Fundamentals of ellipsometry
9.4. Surface enhancement for biosensor applications
9.5. Surface interaction, adsorption, film, and membrane studies
9.6. Immunoassays
9.7. Oligonucleotide and aptamer applications
9.8. Kinetic studies
9.9. Ellipsometry as a characterization tool and combined sensor applications
9.10. Other applications
9.11. Analytical performance improvement studies in ellipsometric biosensors
9.12. Concluding remarks and future perspective
10. Impedance biosensors
10.1. Introduction
10.2. Summary and principles of electrochemical impedance spectroscopy
10.3. Electrode materials, sensor configurations, and surface modifications for use in impedimetric biosensing
10.4. Impedimetric immunosensors
10.5. Impedance-based nucleic acid detection
10.6. Small molecule detection with impedance
10.7. Aptamer-based impedance sensors
10.8. Whole-cell impedimetric biosensors
10.9. Emerging areas—impedance biosensors for infectious disease
10.10. Technological context and limitations
10.11. Summary
11. Nanostructured photoelectrochemical biosensors: materials and applications
11.1. Introduction
11.2. Nanomaterials: electrochemical and optical properties
11.3. Principle of photoelectrocatalysis (PEC)
11.4. Photoelectrochemical biosensors [6,36]
11.5. Conclusions and future perspectives
12. Nucleic acid based impedimetric biosensors
12.1. Introduction
12.2. Aptamer-based impedimetric biosensors
12.3. Impedimetric DNA biosensors
12.4. Impedimetric miRNA biosensors
12.5. Impedimetric biosensors based on new-generation nucleic acids
12.6. Conclusion
Part Three. Sensing materials
13. Metal nanoparticles for sensing applications
13.1. Overview of metallic nanoparticles
13.2. MNPs as analytical sensing platform
13.3. Future perspective and novel applications
13.4. Conclusion and remarks
14. Carbon nanomaterials for sensing applications
14.1. Introduction
14.2. Graphene
14.3. Fullerenes
14.4. Carbon nanotubes
14.5. Carbon nanofibres
14.6. Carbon nanodiamonds
14.7. Carbon nanohorns
14.8. Carbon black
14.9. Carbon dots
14.10. Conclusion and future prospects
15. Polymer nanocomposites for sensing applications
List of abbreviations
15.1. Introduction
15.2. Performance parameters of polymer nanocomposite sensors
15.3. Conducting polymer nanocomposites
15.4. Carbon-based polymer nanocomposites
15.5. Magnetic polymer nanocomposites
15.6. Metal-based polymer nanocomposites
15.7. Molecularly imprinted polymer nanocomposites
15.8. Quantum dot polymer nanocomposites
15.9. Stimuli-responsive polymer nanocomposites
15.10. Application of polymer nanocomposite sensors in agriculture and food and water industries
15.11. Future trends for polymer nanocomposite sensors
15.12. Conclusion
16. Quantum dots for sensing applications
16.1. Introduction
16.2. Fundamentals
16.3. Quantum dots in sensing applications
16.4. Conclusion and remarks
17. Molecularly imprinted polymer sensors: a bridge to advanced diagnostics
17.1. Introduction
17.2. Electrochemical MIP sensors
17.3. Optical MIP sensors
17.4. Conclusion
18. Direct glucose fuel cell towards a self-powered point-of-care nanobiosensor
List of abbreviations
18.1. Introduction
18.2. Electrochemical biosensors
18.3. Direct glucose fuel cell as an alternative power device
18.4. Molecularly imprinted polymers for nano-enhanced biosensing
18.5. Challenges for tailoring a DGFC into a self-powered MIP-based nanobiosensor
18.6. Conclusion and future outlook
19. Metal chalcogenides for sensing applications
19.1. Introduction
19.2. Metal chalcogenide–based optical sensors
19.3. Metal chalcogenide–based colorimetric sensors
19.4. Metal chalcogenide–based fluorescent sensing
19.5. Metal chalcogenide–based optical fiber sensing
19.6. Metal chalcogenide–based electrochemical sensors
19.7. Conclusion
20. Silica nanoparticles for sensing applications
List of abbreviations
20.1. Introduction
20.2. Nonporous silica synthesis and properties
20.3. Nonporous silica nanoparticles for sensing applications
20.4. Mesoporous silica nanoparticles
20.5. Mesoporous silica nanoparticles for sensing applications
20.6. Overview of using silica nanoparticles in sensing applications
20.7. Conclusion and future perspectives
21. Chromo-fluorogenic chemosensors for sensing applications
21.1. Introduction to chemical sensors
21.2. Classification of synthetic chemosensors
21.3. Chromo-fluorogenic chemical sensors for detection of different analytes
21.4. Advantages and disadvantages of chromo-flurogenic chemical sensors
21.5. Trends in synthesis of chromo-fluorogenic chemical sensors
21.6. Sensing enhancement using nanomaterials, polymer, and other supports
21.7. Chromo-fluorogenic chemosensors for point of care sensors
21.8. Conclusions and future perspectives
22. Gold nanoparticle–based biosensing applications and fundamentals of sensor technology: principles and novel designs
List of abbreviations
22.1. Introduction
22.2. Fundamentals of sensor technology: principles and biosensors
22.3. Novel designs of AuNPs for biosensing applications
22.4. Applications
22.5. Conclusions
23. Advances in fiber sensing devices decorated with functionalized nanomaterials
23.1. Introduction
23.2. Single- and multimode passive optical fiber sensing devices
23.3. Active fiber sensing devices
23.4. Fiber Bragg sensing devices
23.5. Microstructured fiber sensing devices
23.6. Conclusions and remarks
Part Four. Recent topics
24. Screen-printed electrochemical sensor platforms
24.1. Introduction
24.2. Screen-printed voltammetric sensors
24.3. Screen-printed impedimetric sensors
24.4. Screen-printed amperometric sensors
24.5. Screen-printed potentiometric sensors
24.6. Conclusions, critical issues, and future direction
25. Biodegradable sensor platforms
25.1. Introduction
25.2. Biodegradable sensor components
25.3. Fabrication strategies for biodegradable devices
25.4. Application of biodegradable sensors
25.5. Conclusion and outlook
26. Disposable paper-based sensors
26.1. Introduction
26.2. Classification of paper-based sensors
26.3. Signal detection techniques
26.4. Principles and applications of paper-based sensors
26.5. Concluding remarks, challenges, and future prospects
Index

Ahmed Barhoum

Dr. Ahmed Barhoum is an Associate Professor of nanomaterials science and Head of the Nanostruc Research Group (Helwan University). He is currently working at the DCU University (Ireland). His research interests include the synthesis of nanomaterials for catalysis, drug delivery, and biosensing. He has won several scientific awards and prizes: Helwan University Prizes (Egypt, 2020 & 2019), CAS Fellowship (China, 2019), IFE Fellowships (France, 2012 & 2018), FWO Fellowships (Belgium, 2015 & 2016), Medastar Erasmus Mundus (Belgium, 2012), Welcome Program (Italy, 2012) and many more. He serves as an expert evaluator for the National Science Centre (NCN, Poland), Czech Science Foundation (GACR, Russia), Swiss National Science Foundation (SNSF, Switzerland), and Innovators Support Fund (ISF, Egypt), among others. He is on the editorial board of Frontiers in Bioengineering and Biotechnology, Frontiers in Nanotechnology, Nanomaterials, and editor of 10 handbooks (Elsevier and Springer Nature), PI/Co-PI of 12 projects, and co-author of 150 publications.

Affiliations and expertise

Head of NanoStruc. Research Group, Chemistry Department, Faculty of Science, Helwan University, Egypt; National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Ireland

Zeynep Altintas

Zeynep Altintas is a full professor and the Chair of Bioinspired Materials and Biosensor Technologies at the University of Kiel, Germany. She has been the Head of Biosensors and Receptor Development Group at the Technical University of Berlin since 2016. She completed her Ph.D. on biomedical sensors at the age of 25 with the outstanding Ph.D. student award. Her Ph.D. period brought her several other research prizes and fellowships. Following a one-year postdoc position at the Cranfield Biotechnology Centre, she continued her academic career as a faculty member of Biomedical Engineering at Cranfield University (the UK) until 2016. She leads an interdisciplinary research group in the domains of biosensor technologies, computational chemistry, receptor design, functional polymers and their applications in (bio)chemical sciences, nanomaterials applications, and design, synthesis, and characterization of biomimetic materials.

Affiliations and expertise

Chair of Bioinspired Materials and Biosensor Technologies, Faculty of Engineering, University of Kiel, Germany. Head of Biosensors and Receptor Development Group, Faculty of Maths and Natural Sciences, Technical University of Berlin, Germany

Life Sciences

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