Functionalized Nanomaterials for Biosensing and Bioelectronics Applications

Trends and Challenges

1st Edition - June 4, 2024
Editors: Sudheesh K. Shukla, Chaudhery Mustansar Hussain, Jagriti Narang, Roberto Pilloton
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 3 8 2 9 - 5
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 3 8 4 3 - 1

Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique proper… Read more

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Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry, and related fields.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Preface
Part 1. Development of fabrication strategies of FNMS based biosensing and bioelectronics
1. Applications of biosensors in bio-analysis
1.1. Introduction
1.2. Principle of biosensors
1.3. Components of biosensors
1.4. Working of biosensors
1.5. Examples of biosensors
1.6. Types of biosensors
1.7. Applications of biosensors
1.8. Conclusions and prospects
2. Biosensing mechanisms and applications
2.1. Introduction
2.2. Signal monitoring
2.3. Immobilization techniques
2.4. Immobilization of biological receptors
2.5. Enzymatic reactions in biosensors
2.6. Transduction mechanisms
2.7. Influence of charge screening on biomolecule detection
2.8. Sensing techniques
2.9. Recent progress in microbial biosensors
2.10. Conclusions and outlook
3. Advantages of functionalized nanomaterials for biosensor technology
3.1. Introduction
3.2. Carbon nanotubes
3.3. Carbon nanotube classification by chirality
3.4. Biological applications
3.5. Limitations of carbon nanotubes
3.6. Quantum dots
3.7. Graphene oxide nanoparticles
3.8. Metal oxide nanoparticles
3.9. Metal nanoparticles
3.10. Magnetic nanoparticles
3.11. Conclusions
4. Nanomaterial functionalization approaches for biosensing and bioelectronic applications
4.1. Introduction
4.2. Carbon-and metal-based nanomaterials
4.3. Electrochemical biosensors
4.4. Optical biosensors
4.5. Conclusions and future perspectives
5. Molecularly imprinted polymer-based sensors: A way-forward concept for artificial antibodies
5.1. Introduction
5.2. Application of nanosized molecularly imprinted polymers
5.3. Nanosized molecularly imprinted polymers as efficient receptors for sensor fabrication
5.4. Conclusions and future perspectives
6. Biosensor development using functionalized 2D nanomaterials
6.1. Introduction
6.2. Biosensors based on analogs of two-dimensional nanomaterials in various fields
6.3. Challenges and outlook
6.4. Conclusions
7. Recent advancements in fabrication strategies for functionalized nanomaterial-based biosensors
7.1. Introduction
7.2. Inkjet printing
7.3. Electrospinning
7.4. Electrodeposition
7.5. Screen printing
7.6. Drop-casting
7.7. Directed self-assembly
7.8. Stamping
7.9. Chemical vapor deposition
7.10. Air suspension coating
7.11. Conclusions
8. Exploring the COVID-19 journey and cutting-edge biosensing approaches
8.1. Introduction
8.2. Unavoidable impacts and risks of infection
8.3. Infectivity emergence
8.4. Evolution of a new SARS-CoV-2 variant: Omicron!
8.5. Potential biosensing technologies
8.6. Vaccine effectiveness
8.7. Interim clinical guidance for management
8.8. Universal recommendations
8.9. Journey, impact, and biosensing approaches: Perspective overview
8.10. Conclusions and prospects
Part 2. Application and future directions of different FNM-based biosensing and bioelectronics
9. Teaming up biosensor technology with agriculture: a detection approach for reframing agricultural sustainability and food security
9.1. Introduction
9.2. Tackling plant diseases and infections in the agricultural sector
9.3. Ensuring agrifood safety and security through biosensing technologies
9.4. Conclusions: current scenario, future perspectives, and challenges
10. Developments and challenges in coronavirus diagnoses: A biosensor point of view
10.1. Introduction
10.2. A sketch of conventional diagnostic methods
10.3. Nonconventional era: The era of antivirals/immune-boosters and vaccines
10.4. Discussion and future perspective
10.5. Conclusions
11. Magnetic graphene nanocomposites for electrochemical detection of heavy metal ions in coal mine areas
11.1. Introduction
11.2. Graphene/graphene oxide
11.3. Electrochemical detection technique
11.4. Conclusions
12. Cancer diagnosis via functionalized nanomaterial-based biosensors
12.1. Introduction
12.2. Cancer diagnosis methods
12.3. Biomarkers
12.4. Biosensors
12.5. Electrochemical biosensors for cancer detection
12.6. Optical biosensors for cancer diagnosis
12.7. Mass spectrometry-based biosensors for cancer diagnosis
12.8. Immunoassay-based biosensors for cancer diagnosis
12.9. Conclusions
13. Biosensors and bioelectronics for advanced healthcare systems
13.1. Introduction
13.2. Historical background of biosensor development
13.3. Static and dynamic characteristics of biosensors
13.4. Classification of biosensors
13.5. Challenges and future approaches in biosensor development
14. Biosensors: A promising approach for healthcare application
14.1. Introduction
14.2. Three-dimensional network: Specific surface attachment of biological elements
14.3. Types of biosensors, their incorporation, and applications
14.4. Biosensor approach for detecting biological applications
14.5. Anticipated property of biosensor
14.6. Conclusion
15. Challenges and prospects of functionalized nanomaterial-based biosensors
15.1. Introduction
15.2. Biosensor development
15.3. Challenges in biosensor development
15.4. Prospects
15.5. Conclusions
Index

Sudheesh K. Shukla

Sudheesh K. Shukla is a researcher with the Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, Johannesburg, South Africa; and Associate Professor at the School of Chemical Engineering and Physical Sciences, Lovely Professional University, Phagwara, India. His research involves real-time analysis of biochemical markers for personalized healthcare and environmental monitoring.

Affiliations and expertise

Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, Johannesburg, South Africa; Department of Biomedical Engineering, School of Biological Engineering and Life Science, Shobhit Institute of Engineering & Technology (Deemed-to-be University), Modipuram, Meerut, India; School of Chemical Engineering and Physical Sciences, Lovely Professional University, Phagwara, India

Chaudhery Mustansar Hussain

Prof. Chaudhery Mustansar Hussain is an Adjunct Professor and Director of laboratories in the Department of Chemistry & Environmental Sciences at the New Jersey Institute of Technology (NJIT), United States. His research is focused on the applications of nanotechnology and advanced materials, environmental management, analytical chemistry, and other various industries. Dr. Hussain is the author of numerous papers in peer-reviewed journals as well as a prolific author and editor of around 150 books, including scientific monographs and handbooks in his research areas.

Affiliations and expertise

Adjunct Professor and Director of laboratories, New Jersey Institute of Technology (NJIT), USA

Jagriti Narang

Jagriti Narang is an Assistant Professor at the Department of Biotechnology, Jamia Hamdard, New Delhi, and has work experience of more than 10 years. She has authored or coauthored many research papers in international peer-reviewed journals. She has edited four books and written several chapters. She is a committee member of many international conferences and is a member of Material Research Society of India and Society of Biological Chemistry. She is also an editor and peer reviewer of many international journals and has presented her papers on several international platforms. Dr. Narang has done extensive work on the fabrication of various biosensors for the diagnostic applications. She has proposed some laboratory models that can be converted into commercial monitoring device.

Affiliations and expertise

Department of Biotechnology, School of Chemical and Life Science, Jamia Hamdard University, New Delhi, India

Roberto Pilloton

Since 1986, Roberto Pilloton has been at the forefront of advancing bioanalytical methods through the innovative use of electrochemical biosensors, particularly in the domains of food, clinical, and environmental analysis. His distinguished career includes roles as a senior researcher at two of Italy's leading research institutes: the ENEA "Italian Institute of Sustainable Development" and the CNR "National Research Council." In addition to his impactful research contributions, Pilloton has imparted his knowledge as an adjunct professor, specializing in Environmental Bioanalytical Chemistry, across several esteemed Italian universities and research institutes. His dedication to education is further demonstrated by his role as a mentor, guiding students in the development of master's and PhD theses, as well as mentoring national and international fellows. Pilloton's global influence extends beyond academic circles, as he has served as a visiting scientist in prominent institutions in Paris, Stuttgart, Nice, Braunschweig, Lund, Izmir, Ceske Budejovice, and Karaikudi. Moreover, he has played a pivotal role in shaping the landscape of international conferences on biosensors, having chaired or been a member of the scientific committee. From 2015 to 2018, Pilloton served as the elected vice president of the "International Association on Environmental Analytical Chemistry" (IAEAC). Currently, he holds the esteemed position of Editor-in-Chief of the International Journal of Environmental Analytical Chemistry at Taylor and Francis, and he is a valuable member of the editorial boards of two MDPI journals: Sensors and Biosensors.

Affiliations and expertise

Institute of Crystallography, National Research Council (CNR-IC), Rome, Italy