Functionalized Magnetic Nanosystems for Diagnostic Tools and Devices
Current and Emerging Research Trends
- 1st Edition - January 12, 2024
- Imprint: Elsevier
- Editors: Kalim Deshmukh, Chaudhery Mustansar Hussain
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 1 2 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 1 1 - 7
Functionalized Magnetic Nanosystems for Diagnostic Tools and Devices: Current and Emerging Research Trends explores the various aspects of functionalization of magnetic nanosy… Read more
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Request a sales quoteFunctionalized Magnetic Nanosystems for Diagnostic Tools and Devices: Current and Emerging Research Trends explores the various aspects of functionalization of magnetic nanosystems in great detail, providing a thorough review of the associated benefits and challenges. The book begins with an overview of each key pillar for the design and application of functionalized magnetic nanosystems, from the synthesis, processing methods, and characterization techniques, to biocompatibility and toxicity considerations. Later chapters focus on specific nanomaterials and targeted biomedical applications, including point-of-care diagnosis, cancer therapy, medical imaging, biosensing and more. Importance is given to the safety considerations, environmental, legal and ethical implications, and commercial aspects of functionalized magnetic nanosystems, thus providing guidance relevant for advancing research into clinical practice.
- Provides an overview of fundamentals in the design and application of magnetic nanosystems, from synthesis and processing to functionalization and toxicity assessment
- Explores research in industry and clinical practice, providing insights into ethical, environmental, legal, and commercial aspects
- Covers a wide range of diagnostic applications for functionalized magnetic nanosystems, such as in medical imaging, drug detection, tissue engineering, and more
Researchers and postgraduate students in the fields of materials science, biomedical engineering, analytical chemistry and nanotechnology.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter 1 Introduction to magnetic nanosystems: Classifications, structure, properties, biological interactions, and diagnostic applications
- Abstract
- 1 Introduction
- 2 Definition of magnetic nanoparticles and nanomagnetism
- 3 Synthesis of magnetic nanoparticles
- 4 Physicochemical features and characterization
- 5 Structural classification of magnetic nanoparticles
- 6 Biological interactions
- 7 Diagnostic applications
- 8 Challenges and future perspectives
- 9 Conclusion
- References
- Chapter 2 Synthesis and processing methods of magnetic nanosystems for diagnostic tools and devices: Design strategies and physicochemical aspects
- Abstract
- Acknowledgments
- Conflict of interest
- 1 Introduction
- 2 Fundamental characteristics, barriers, and endocytosis mechanism of MNPs
- 3 Targeting strategy of MNPs via active and passive approach
- 4 Various methods of MNPs synthesis
- 5 Dendrimer-encapsulated-(DE)-MNPs: Synthesis and characterization
- 6 Medical use of MNPs for diagnosis and imaging of diseases
- 7 Ongoing and finished clinical trials of MNPs
- 8 Limitation of MNPs to be used in preclinical and clinical studies
- 9 Challenges and future prospective
- 10 Conclusion
- References
- Chapter 3 Surface functionalization and modification strategies of magnetic nanosystems
- Abstract
- 1 Introduction
- 2 Magnetic iron oxide nanomaterials
- 3 Magnetic cobalt oxide nanomaterials
- 4 Magnetic nickel oxide nanomaterials
- 5 Conclusion
- References
- Chapter 4 Characterization techniques of functionalized magnetic nanosystems
- Abstract
- 1 Introduction
- 2 Size and shape determination
- 3 Structural properties determination
- 4 Chemical characterization
- 5 Magnetic properties
- 6 Mössbauer spectroscopy
- 7 Synchrotron radiation-based spectroscopy
- 8 Conclusions
- References
- Chapter 5 Biocompatibility and toxicity assessments of functionalized magnetic nanosystems
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Magnetic nanosystems in nanotechnology
- 3 Different members of the magnetic nanosystems
- 4 Concept of biocompatibility
- 5 Toxicity
- 6 Concept of nanotoxicology
- 7 Future prospectives
- 8 Conclusions
- References
- Chapter 6 Functionalized magnetic nanosystems for diagnostic tools and devices: New perspectives in disease diagnosis
- Abstract
- 1 Introduction
- 2 Surface modification approaches of MNPs
- 3 MNPs as diagnostic tools
- 4 Future perspectives and conclusion
- References
- Chapter 7 Functionalized magnetic nanosystems for point-of-care and point-of-need diagnostic applications
- Abstract
- 1 Introduction
- 2 Imaging applications
- 3 Molecular diagnostic applications
- 4 Applications in biorecognition
- 5 Biosensing applications
- 6 Microfluidics/lab-on-a-chip
- 7 Point-of-need diagnostics in epidemics
- 8 Challenges and future perspectives
- 9 Conclusion
- References
- Chapter 8 Functionalization of biogenic and biomimetic magnetic nanosystems for biomedical applications
- Abstract
- Acknowledgment
- 1 Introduction
- 2 Synthesis of biogenic MNPs
- 3 Physicochemical and structural characterization of magnetic nanoparticles
- 4 Magnetic nanoparticles in biomedical applications
- 5 Challenges and future perspectives
- 6 Conclusion
- References
- Chapter 9 Functionalized magnetic nanosystems for cancer diagnosis and therapy
- Abstract
- 1 Introduction
- 2 Magnetic nanosystems: Synthesis and their functionalization
- 3 Functionalized magnetic nanosystems for cancer diagnosis
- 4 Functionalized magnetic nanosystems for cancer therapy
- 5 Functionalized magnetic nanosystems for theranostics
- 6 Challenges and future perspective
- 7 Conclusion
- References
- Chapter 10 Functionalized magnetic nanosystems for immobilization of proteins and enzymes
- Abstract
- 1 Introduction
- 2 Protein and enzyme immobilized functionalized magnetic nanosystems
- 3 Conclusion and future perspectives
- References
- Chapter 11 Functionalized magnetic nanosystems for diagnostic tools and devices in bio-barcodes and smartphones
- Abstract
- 1 Introduction
- 2 Smartphone
- 3 Bio-barcodes
- 4 Artificial intelligence, stem-cells, and 3D-printing integrated with bio-barcodes and smartphones for point-of-care-testing (POCT)
- 5 Conclusion and future perspective
- References
- Chapter 12 Functionalized magnetic nanosystems for medical imaging
- Abstract
- 1 Introduction
- 2 MRI imaging
- 3 MRI-FI dual imaging
- 4 MRI-PET dual imaging
- 5 MRI-multimodal imaging
- 6 Conclusion and future prospectus
- References
- Chapter 13 Functionalized magnetic nanosystems for drug delivery applications
- Abstract
- 1 Introduction
- 2 Structure of magnetic nanoparticles used in drug delivery applications
- 3 Synthesis of magnetic nanoparticles
- 4 Use of magnetic nanoparticles for delivery of therapeutics
- 5 Drug encapsulation
- 6 Delivery of nucleic acids for gene therapy
- 7 Magnetic nanoparticle-assisted drug delivery using tissue-engineered scaffolds
- 8 Toxicity of functionalized nanoparticles for drug delivery
- 9 Conclusions and perspectives
- References
- Chapter 14 Functionalized magnetic nanosystems for tissue engineering
- Abstract
- 1 Introduction
- 2 FMNs for tissue engineering
- 3 Summary and perspectives
- References
- Chapter 15 Functionalized magnetic nanosystems for molecular detection of biomarkers
- Abstract
- 1 Introduction
- 2 Synthesis of functionalized magnetic nanosystems for molecular diagnosis of biomarkers
- 3 Classification of molecular biomarkers
- 4 Rationale of using functionalized magnetic nanosystems for molecular biomarker diagnostics
- 5 Applications of biomarkers
- 6 Functionalized magnetic nanosystems for the screening and diagnosis of cancer biomarkers
- 7 Functionalized magnetic nanosystems for the diagnosis of infectious diseases using biomarkers
- 8 Investigative methods for the detection for molecular biomarkers
- 9 Nanotechnologies for molecular diagnostics of biomarkers
- 10 Nanotechnology-based biomarker detection using cytogenetics
- 11 Clinical trials of biomarker-based nanodiagnostics
- 12 Current challenges and future perspectives
- 13 Conclusions
- References
- Chapter 16 Functionalized magnetic nanosystems for the detection and control of infectious diseases
- Abstract
- 1 Introduction
- 2 MNP synthesis techniques
- 3 Magnetic nanostructures composition
- 4 Magnetic nanoparticles functionalization
- 5 Magnetic nanoparticles applications
- 6 Conclusion and future perspectives
- References
- Chapter 17 Functionalized magnetic nanosystems in nanomedicine
- Abstract
- Acknowledgments
- 1 Introduction to magnetic nanoparticles
- 2 Different types of functionalization for magnetic nanoparticles
- 3 Diagnostic and therapeutic application of magnetic nanoparticles in cancer
- 4 Applications of functionalized magnetic nanoparticles for inflammation
- 5 Functionalized magnetic nanoparticles against fungal infections
- 6 Functionalized magnetic nanoparticles as antimicrobial agents
- 7 Functionalized magnetic nanoparticles used for clinical translation
- 8 Challenges and future perspectives
- 9 Conclusion
- References
- Chapter 18 Functionalized magnetic nanosystems for in-vivo diagnosis and therapy
- Abstract
- 1 Introduction
- 2 Classification of magnetic nanosystems (MNSs)
- 3 Methods of synthesis
- 4 Surface functionalization strategies
- 5 Formulation consideration
- 6 In vivo applications
- 7 Metabolic pathways and cytotoxicity
- 8 Conclusion and future aspects
- References
- Chapter 19 Functionalized magnetic nanosystem-based electrochemical sensors for medical diagnostic tools and devices
- Abstract
- 1 Electrochemical sensors
- 2 Magnetism and sensing
- 3 Magnetic systems and their role in electrochemical sensing
- 4 Functionalization of magnetic nanosystems
- 5 Applications
- 6 Challenges and future perspectives
- 7 Conclusion
- References
- Chapter 20 Functionalized magnetic nanosystems for narco-drug detections and military applications
- Abstract
- 1 Introduction
- 2 Magnetic nanosystems
- 3 Conclusion
- References
- Chapter 21 Polymer-mediated functionalized magnetic nanosystems for biomedical applications
- Abstract
- 1 Introduction
- 2 PNIPAM/Fe2O3 thermoresponsive nanocomposites for biomedical applications
- 3 PAA/Fe2O3 hydrophilic nanocomposites for biomedical applications
- 4 PVA/Fe2O3 hydrophilic nanocomposites for biomedical applications
- 5 PSS/Fe2O3 nanocomposites for biomedical applications
- 6 PEG/Fe2O3 hydrophilic nanocomposites for biomedical applications
- 7 Chitosan/Fe2O3 green nanocomposites for biomedical applications
- 8 PMMA/Fe2O3 biocompatible nanocomposites for biomedical application
- 9 Polyurethane/Fe2O3 biocompatible nanocomposites for biomedical application
- 10 Preparing Fe2O3 nanocomposites using PVP surfactant for biomedical applications
- 11 Polylactic acid/Fe2O3 biocompatible nanocomposites for biomedical applications
- 12 Poly(N-vinylcaprolactam)/Fe2O3 thermoresponsive nanocomposites for biomedical applications
- 13 Polyaniline/Fe2O3 conductive nanocomposites for biomedical applications
- 14 PVC/Fe2O3 nanocomposites for biomedical application
- 15 Starch/Fe2O3 green nanocomposites for biomedical applications
- 16 Other polymers
- 17 Conclusions
- References
- Chapter 22 Mesoporous core-shell-structured functionalized magnetic nanosystems for diagnostic tools and devices
- Abstract
- 1 Introduction
- 2 Synthesis and characterization of mesoporous core/shell structured functionalized magnetic nanosystems
- 3 Biomedical applications as diagnostic tools and devices
- 4 Conclusions
- References
- Chapter 23 Functionalized magnetic nanogels for diagnostic tools and devices
- Abstract
- 1 Introduction
- 2 Preparation strategies of magnetic nanogels
- 3 Techniques to synthesize magnetic nanoparticles
- 4 Functionalization approaches for magnetic nanoparticles
- 5 Applications of functionalized magnetic nanogels in diagnostic tools and devices
- 6 Conclusion and future perspective
- References
- Chapter 24 Functionalized magnetic nanocomposites/hybrids for diagnostic tools and devices
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Iron oxide
- 3 Gadolinium
- 4 Manganese
- 5 Other nanomaterials
- 6 Challenges and future prospects
- 7 Conclusion
- References
- Chapter 25 Safety considerations, environmental, legal, and health impact of functionalized magnetic nanosystems
- Abstract
- 1 Nanotechnology: Current state
- 2 Potential market value of nanomaterials
- 3 Applications of magnetic and its functionalized nanosystems
- 4 Exposure
- 5 Nano safety and risk assessment
- 6 Health impact of magnetic nanosystem in humans
- 7 Safety consideration in nanotechnology
- 8 Current and future challenges in policymaking
- 9 Future perspective and conclusion
- References
- Chapter 26 A futuristic insight into functionalized magnetic nanosystems for diagnostic tools and devices: From lab to commercial applications
- Abstract
- 1 Introduction
- 2 Biomedical applications of functionalized magnetic nanosystems
- 3 Commercialization steps of magnetic nanoparticles
- 4 Challenges and market restraints
- 5 Examples of marketed magnetic nanosystems
- 6 Market share past, present, and future
- 7 Conclusions
- References
- Index
- Edition: 1
- Published: January 12, 2024
- No. of pages (Paperback): 794
- No. of pages (eBook): 700
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780443190124
- eBook ISBN: 9780443190117
KD
Kalim Deshmukh
Kalim Deshmukh is a Senior Researcher at the New Technologies-Research Centre, University of West Bohemia, Pilsen, Czech Republic. He has over 20 years of research experience working with various nanostructured materials, and polymeric materials, especially polymer blends, and nanocomposites for numerous applications. His research interest is mainly focused on the synthesis, characterization,
and evaluation of the structure–property relationships of different polymers reinforced with various nanofillers including metal and metal oxide nanoparticles, carbon allotropes, and novel 2D nanomaterials for energy storage, gas sensing and EMI shielding applications.
Affiliations and expertise
Senior Researcher, New Technologies - Research Centre, University of West Bohemia, Czech RepublicCM
Chaudhery Mustansar Hussain
Chaudhery Mustansar Hussain is an Adjunct Professor and Director of Laboratories in the Department of Chemistry & Environmental Sciences at the New Jersey Institute of Technology (NJIT), Newark, New Jersey, United States. His research is focused on the applications of nanotechnology and advanced materials, environmental management, analytical chemistry, and other industries. Dr. Hussain is the author of numerous papers in peer-reviewed journals as well as a prolific author and editor in his research areas. He has published with Elsevier, the American Chemical Society, the Royal Society of Chemistry, John Wiley & Sons, CRC Press, and Springer.
Affiliations and expertise
Adjunct Professor & Director of Laboratories, New Jersey Institute of Technology (NJIT), Newark, NJ, USARead Functionalized Magnetic Nanosystems for Diagnostic Tools and Devices on ScienceDirect