From Cyclotrons To Cytochromes
Essays in Molecular Biology and Chemistry
- 1st Edition - January 1, 1982
- Editor: Nathan Kaplan
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 9 7 5 8 0 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 4 2 0 5 - 2
From Cyclotrons to Cytochromes: Essays in Molecular Biology and Chemistry focuses on the uses of the cyclotron and radioactive isotopes in molecular biology and chemistry. The book… Read more
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Request a sales quoteFrom Cyclotrons to Cytochromes: Essays in Molecular Biology and Chemistry focuses on the uses of the cyclotron and radioactive isotopes in molecular biology and chemistry. The book includes a tribute to Martin Kamen, who played an important role in the development of biochemical sciences in the United States, particularly through his research on the cyclotron. The text also documents research on isotopes carried out at the Radiation Laboratory of the University of California at Berkeley during the 1930s, as well as the role of radioactive carbon in bacterial metabolism and experimental work on cytochromes. This volume is organized into six sections encompassing 54 chapters and begins with an overview of science and technology, and then discusses carbon-14 and its half-life. The next chapters discuss the chemistry and structure of cytochromes; the role of cytochromes and redox systems in photosynthesis; the biological aspects of phosphorylation and oxidation; and protein structure. The book also methodically explains the regulatory mechanisms and miscellaneous metabolic processes such as the metabolism of cyclic nucleotides and related compounds; biological functions of lactate dehydrogenase; and nucleotide excision repair of damaged DNA. The final chapter discusses the deamidation of asparagine and glutamine side chains when incorporated into polypeptide chains, with reference to the role of cryptic amidase active sites in catalyzing the process. This book is a valuable resource for biochemists and molecular biologists.
Contributors
Prologue
Introduction
A Letter
Everything I've Always Wanted to Know about Cytochromes but Did Not Dare to Ask
Some Memories, Some Joys
Science, Technology, and the Quality of Life
Isotopes
Isotopes at Berkeley in the Thirties
Why Is the Half-Life of 1 4C So Long
Two Isotopes Are Better than One
Tracers in Biology
Radioactive Carbon in Bacterial Metabolism: Something Old and Something New
The Reemergence of Positron-Emitting Isotopes as Tracers of Metabolism: A New Approach for Measuring Changes in Rates of Cellular Proliferation in Vivo
From CO2 to Acetate
From Glycine to Heme
Cytochromes: Chemistry and Structure
Chemical Evolution and Chemical Innovation
Cytochrome c1—An Inert Cytochrome
Cytochromes and Ferredoxins in Bacterial Electron Transport and Classification
The Structure and Catalytic Mechanisms of Cytochrome c
Investigation of Cytochromes at Subzero Temperatures
Reduction Kinetics of Chromatium vinosum Cytochrome c
Toward a Common Structural Concept for P-450 Heme Proteins
Thiobacillus novellus Cytochrome Oxidase
The Structure and Classification of Cytochrome c
Phosphorylation, Oxidation, and Photosynthesis
Fifty Years of ATP
Biological Phosphorylation,32P, and Fifty Years of ATP
Cytochromes and Redox Systems in Photosynthesis
The Comparative Biochemistry of Photosynthesis: Milestones in a Conceptual Zigzag
Studies on the Oxygen-Evolving System of Photosynthesis: Are There Nonlinear Misses?
Photophosphorylation after Single Turnover Light Flashes in Chromatophores from Rhodospirillum rubrum
Composition and Development of the Bacterial Photosynthetic Apparatus
Active Components Bound to the Chromatophore Membrane of Rhodospirillum rubrum
Studies on Carotenes in Bacterial Reaction Centers
The Relationship between Photosynthesis and Nitrogen Fixation Revisited
Nitrogenase: Preparative Methods as a Basis for New Investigative Approaches or When Less Cytochrome is Better
Structure and Function of Membrane-Bound Proteins from M. phlei
The Dopamine Hydroxylating System of Bovine Adrenal Chromaffin Granules
Protein Structure
Concerted Hydrogen Bond Changes in Protein Conformational Transitions
Prediction of the Secondary Structure of Proteins
Substrate Specificity and Characteristics of Alcohol Dehydrogenase and Other Human Liver ADH Isoenzymes
Intrinsic Binding Energy, Enzymatic Catalysis, and Coupled Vectorial Processes
Oxygen Inactivation and Stabilization of Azotobacter Nitrogenase
Regulatory Mechanisms and Metabolic Miscellany
Hormones of the Anterior Pituitary Gland
Saint-Agnes, Music, and Sporulation
Molecular Mechanisms and Function of Bioluminescence in Fishes
Regulation of Yeast Hexokinase Activity
Deacylation of Cellular Lipids: An Assay for Tumor Promoters
Metabolism of Cyclic Nucleotides and Related Compounds in Different Layers of the Retina
Biological Functions of Lactate Dehydrogenase
Some Observations on the Evolution of the Regulation of the de Novo Pathway for UMP Biosynthesis in Prokaryotes
The Purine Nucleotide Cycle in Brain
Similarity Analysis Based upon Ribosomal Protein Compositions in Rhodospirillaceae Family: Initiatory Trail
Nucleotide Excision Repair of Damaged DNA
Genetic Structure of a Plasmic Replicon
Definition of a Disease: Experimental Allergic Encephalomyelitis
Cryptic Amidase Active Sites Catalyze Deamidation in Proteins
Appendix
Index
- No. of pages: 903
- Language: English
- Edition: 1
- Published: January 1, 1982
- Imprint: Academic Press
- Hardback ISBN: 9780123975805
- eBook ISBN: 9780323142052
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