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Forensic DNA Typing
Biology, Technology, and Genetics of STR Markers
2nd Edition - October 24, 2004
Author: John M. Butler
Hardback ISBN:9780121479527
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eBook ISBN:9780080470610
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Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of… Read more
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Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today.
The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable.
This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science.
*The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome *Chapters cover the topic from introductory level right up to "cutting edge" research *High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases *NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
Researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. Law enforcement, legal professionals, government/legal policy makers.
Ch. 1: Overview & History of DNA Typing Ch. 2: DNA Biology Review Ch. 3: Sample Collection, DNA Extraction, and DNA Quantitation Ch. 4: The Polymerase Chain Reaction (DNA Amplification) Ch. 5: Commonly Used Short Tandem Repeat Markers and Commercial Kits Ch. 6: Biology of STRs Ch. 7: Forensic Issues Ch. 8: Single Nucleotide Polymorphisms & Other Bi-allelic Markers Ch. 9: Y-Chromosome DNA Testing Ch. 10: Mitochondrial DNA Analysis Ch. 11: Non-Human DNA and Microbial Forensics Ch. 12: DNA Separation Methods Ch. 13: DNA Detection Methods Ch. 14: Instrumentation for STR Typing Ch. 15: STR Genotyping Issues Ch. 16: Laboratory Validation Ch. 17: New Technologies, Automation, and Expert Systems Ch. 18: CODIS and DNA Databases Ch. 19: Basic Genetic Principles, Statistics, & Probability Ch. 20: STR Population Database Analyses Ch. 21: Profile Frequency Estimates, Likelihood Ratios & Source Attribution Ch. 22: Approaches to Statistical Analysis of Mixtures and Degraded DNA Ch. 23: Kinship and Parentage Testing Ch. 24: Mass Disaster DNA Victim Identification
App I: Reported STR Alleles App II: Population Data-STR Allele Frequencies App. III: Suppliers of DNA Analysis Supplies App. IV: DAB QA Standards App. V: DAB Recommendations on Statistics App. VI: NRC II Recommendations App. VII: Example DNA Cases
No. of pages: 688
Language: English
Published: October 24, 2004
Imprint: Academic Press
Hardback ISBN: 9780121479527
eBook ISBN: 9780080470610
JB
John M. Butler
John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch’s #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit http://www.cstl.nist.gov/strbase/butler.htm.
Affiliations and expertise
NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland.