Fiber and Textile Engineering in Drug Delivery Systems
- 1st Edition - December 5, 2022
- Imprint: Woodhead Publishing
- Editors: Navneet Sharma, Bhupendra Singh Butola
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 6 1 1 7 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 5 0 0 - 9
Fiber and Textile Engineering in Drug Delivery Systems explains how innovative textile processing methods including rotary spinning, microfluidics, wet spinning and electrosp… Read more
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Request a sales quoteFiber and Textile Engineering in Drug Delivery Systems explains how innovative textile processing methods including rotary spinning, microfluidics, wet spinning and electrospinning can be used to produce novel drug delivery solutions. This topical book provides detailed descriptions of how to produce such new materials for this purpose, with foundational content to help readers from a range of backgrounds understand the context of material selection and design decisions. Emphasis is given to the engineering side of the manufacturing of the textile and its role in drug delivery, but this also acts as a guide to pharmaceutical applications of textile fibers for materials scientists.
Drug delivery research is rapidly expanding and experimenting with new materials to drive improved clinical outcomes as the efficacy of the therapeutic molecule is highly dependent on the right choice of carrier system. Recently, fiber based carriers at both nano and micro scales are gaining interest in the scientific community due to ease of manufacturing, high surface area to volume ratio, desirable drug release kinetics and high mechanical strength.
- Describes methods for material selection and design for drug delivery systems
- Provides case studies to explain how these techniques can be applied successfully
- Covers the regulatory and legal aspects of the use of the textiles and fibers in drug delivery
Researchers in industry and academia with an interest in applications of textiles in biomedicine, or innovative drug delivery systems
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- 1. Drug-releasing textile materials: current developments and future perspectives
- Abstract
- 1.1 Introduction
- 1.2 Historical development of drug-releasing textile
- 1.3 Classes of drug-releasing textile materials
- 1.4 Mechanisms of controlled drug delivery through textile materials and their pharmacokinetics
- 1.5 Fabrication of drug delivery systems
- 1.6 Evaluation of drug-releasing textile materials
- 1.7 Drug-releasing textile materials applications
- 1.8 Future prospective
- 1.9 Conclusion
- Acknowledgments
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 2. Current approaches in nanofiber-based drug delivery systems: methods and applications
- Abstract
- 2.1 Introduction
- 2.2 Electrospinning principle and its fundamentals
- 2.3 Method for incorporation of drug using electrospinning
- 2.4 Stimuli-responsive drug delivery using smart electrospun nanofibers
- 2.5 Clinically used electrospun nanofiber-based biomedical drug delivery systems/devices
- 2.6 Biomedical applications of electrospun nanofiber-based drug delivery systems
- 2.7 Conclusion and future perspectives
- Acknowledgments
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 3. Biomaterial-based fibers for enhanced wound healing and effective tissue regeneration
- Abstract
- 3.1 Introduction
- 3.2 Biomaterials
- 3.3 Synthesis of fibers
- 3.4 Characterization of fibers
- 3.5 The anatomy of skin
- 3.6 Wound healing and repair
- 3.7 Characteristics of ideal dressing and lacunae with present biomaterial dressings
- 3.8 Nanoparticle-based wound therapies
- Acknowledgments
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 4. Biomaterials and biomaterial-based fibers in drug delivery systems
- Abstract
- 4.1 Introduction
- 4.2 Methods for drug delivery system
- 4.3 Biomaterials-based drug delivery
- 4.4 Biomaterials-based fibers in drug delivery systems
- 4.5 Conclusion
- Acknowledgments
- Author contributions
- Compliance with ethical standard
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 5. Biomedical applications of carbon nanotubes
- Abstract
- 5.1 Introduction
- 5.2 Properties of carbon nanotubes
- 5.3 Types of carbon nanotubes
- 5.4 Characterization techniques
- 5.5 Synthesis of carbon nanotubes
- 5.6 Biocompatibility, biodistribution, and biodegradability of carbon nanotubes
- 5.7 Toxicity
- 5.8 Carbon nanotube modification: toward reduction of its toxicity issues
- 5.9 Biomedical applications of carbon nanotubes
- 5.10 Future aspects
- 5.11 Conclusion
- Acknowledgment
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 6. Scope of using hollow fibers as a medium for drug delivery
- Abstract
- 6.1 Introduction
- 6.2 Drug delivery systems
- 6.3 Hollow fibers
- 6.4 Types of hollow fibers
- 6.5 Hollow fibers for drug delivery
- 6.6 Ion exchange hollow fiber membranes
- 6.7 Fabrication techniques for hollow fibers
- 6.8 Drug-loading in hollow fiber
- 6.9 Mechanism of drug release via hollow fiber
- 6.10 Drug release kinetics
- 6.11 Drug delivery applications of hollow fibers associated with different organ systems
- 6.12 Other drug delivery applications of hollow fibers
- 6.13 Prospects
- Acknowledgments
- Authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 7. Deciphering plausible role of DNA nanostructures in drug delivery
- Abstract
- 7.1 Introduction
- 7.2 Evolution of nanoscience
- 7.3 Nano-bio interface
- 7.4 DNA nanotechnology
- 7.5 DNA nanostructures
- 7.6 Holliday junction in designing DNA nanostructures
- 7.7 DNA aptamers in functionalizing DNA nanostructures
- 7.8 Structural DNA nanotechnology
- 7.9 Dynamic DNA nanotechnology
- 7.10 Why are DNA nanostructures suitable for drug delivery?
- 7.11 Modes of drug delivery
- 7.12 Recent advances in DNA nanostructure-mediated drug delivery
- 7.13 Pros and cons of DNA nanostructures in drug delivery
- 7.14 Outlook and future perspective
- Authors’ contribution
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 8. Multifaceted approach for nanofiber fabrication
- Abstract
- 8.1 Introduction
- 8.2 Fabrication techniques
- 8.3 Application of nanofibers
- 8.4 Conclusions
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 9. Electrospun nanofiber a smart drug carriers: production methods, problems, solutions, and applications
- Abstract
- Graphical abstract
- 9.1 Introduction
- 9.2 Advantages of electrospun nanofiber
- 9.3 Methods of electrospinning
- 9.4 Applications of electrospinning
- 9.5 Conclusion and outlook
- Acknowledgments
- Authors’ contribution
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 10. Potential of stem cells in combination with natural and synthetic polymer hydrogel for wound healing dressing
- Abstract
- 10.1 Introduction
- 10.2 Physiology of wound healing
- 10.3 Approaches to heal wound
- 10.4 Biomaterial used in wound healing
- 10.5 Wound healing dressings
- 10.6 Application of hydrogel in wound healing
- 10.7 Stem cells in wound healing
- 10.8 Cell-based wound dressing
- 10.9 Limitation of biomaterials dressing in wound healing
- 10.10 Conclusion
- Acknowledgment
- Authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- Funding
- References
- 11. Next-generation bandages to overcome oxygen limitation during wound healing/tissue repair
- Abstract
- 11.1 Introduction
- 11.2 Role of oxygen in wound healing
- 11.3 Conventional wound dressings
- 11.4 Limitations of conventional dressings
- 11.5 Next-generation bandages
- 11.6 Oxygen therapies
- 11.7 Conclusion
- Acknowledgment
- Authors’ contributions
- Compliance with ethical standards
- Permissions
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 12. Fiber and textile in drug delivery to combat multidrug resistance microbial infection
- Abstract
- 12.1 Introduction
- 12.2 Common textile antimicrobial agent
- 12.3 Nanoparticles-based fabrics for the treatment of antimicrobial infection
- 12.4 Electrospun-based fabrics for the treatment of antimicrobial infection
- 12.5 Antibiotics-loaded fabrics for the treatment of antimicrobial infection
- 12.6 Application of nanoparticles against MDROs: merits and demerits
- 12.7 Conclusion
- Acknowledgement
- Authors’ contribution
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 13. Emulsion templated three-dimensional porous scaffolds for drug delivery
- Abstract
- 13.1 Introduction
- 13.2 Emulsion templated scaffolds
- 13.3 High internal phase emulsion templates for drug encapsulation
- 13.4 Conclusion
- Acknowledgments
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 14. Nanotubes-based brain targeted drug delivery system: a step toward improving bioavailability and drug enhancement at the target site
- Abstract
- 14.1 Introduction
- 14.2 Carbon nanotubes as a loaded vehicle for therapeutic delivery
- 14.3 Neurological disorder and requisite for drug delivery across the blood-brain-barrier
- 14.4 Plausible drug delivery strategies by carbon nanotubes in brain cancer therapy
- 14.5 Repair and regeneration of neurons by carbon nanotubes
- 14.6 Neurotoxicity and biocompatibility of carbon nanotubes
- 14.7 Cellular fate of carbon nanotubes
- 14.8 Conclusion
- Acknowledgements
- Individual authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- 15. Functional designing of textile surfaces for biomedical devices
- Abstract
- 15.1 Introduction
- 15.2 Functional designing of polyester
- 15.3 Applications of functional polyesters
- 15.4 Conclusion
- Acknowledgments
- Individual authors’ contributions
- Compliance of interest
- Research involving human participants and animals
- Informed consent
- References
- 16. Metal/metal oxide nanoparticles reinforced biocomposites for drug delivery
- Abstract
- 16.1 Introduction
- 16.2 Nano-biocomposites
- 16.3 Biopolymer
- 16.4 Nanofillers
- 16.5 Metal/metal oxide nanoparticles-reinforced biocomposites
- Conclusion
- Acknowledgments
- Authors’ contributions
- Compliance with ethical standards
- Conflict of interest
- Research involving human participants and animals
- Informed consent
- References
- Index
- Edition: 1
- Published: December 5, 2022
- Imprint: Woodhead Publishing
- No. of pages: 522
- Language: English
- Paperback ISBN: 9780323961172
- eBook ISBN: 9780323995009
NS
Navneet Sharma
Dr. Navneet Sharma is an Assistant Professor at the Amity Institute of Pharmacy, Amity University, India. He has an M.Pharm, Ph.D and PGDRA, and his expertise lies in the realm of biomaterials and applied R & D, especially needs-based product development. He has taken pivotal roles as an investigator in three projects supported by DST-India. He has won several awards, including eight national and international awards. The most prestigious among them are SCO and Ministry of External Affairs, Government of India Covid-19 best innovation award 2020, and Department of Science and Technology, Young Scientist Award for the year 2018 and 2022. He has more than 40 publications including four books, five book chapters, 10 patents and 4 technologies successfully transferred to the industry.
Affiliations and expertise
Scientist, Institute of Information Technology (IIT), Delhi, IndiaBB
Bhupendra Singh Butola
B. S. Butola is a Professor at the Department of Textiles & Fibre Engineering, IIT Delhi, India. His research interests include functionalization of textiles with metal oxides, use of shear thickening fluids for improving the impact performance of ballistic textiles, polymeric nanocomposites and smart colorants. He has edited 7 books.
Affiliations and expertise
Professor, Department of Textile and Fiber Engineering, IIT Delhi, IndiaRead Fiber and Textile Engineering in Drug Delivery Systems on ScienceDirect