Fetal and Neonatal Neurology and Neurosurgery
- 4th Edition - April 10, 2014
- Authors: Frank A. Chervenak, Malcolm I. Levene
- Language: English
- eBook ISBN:9 7 8 - 0 - 7 0 2 0 - 5 0 5 0 - 3
This book provides a definitive reference work on the developing brain, from conception through the first year of life. Its purpose is to provide the range of specialists involved… Read more

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Request a sales quoteThis book provides a definitive reference work on the developing brain, from conception through the first year of life. Its purpose is to provide the range of specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system, so that they can provide prompt and informed treatment of neurological disability – the most feared complication of pregnancy and the early months of the life of the newborn child.
- A cross-specialty book: brings together the work of specialists on the immature brain from the fields of obstetrics, paediatrics and neurosurgery.
- An international book: edited and written by an international team of experts.
- Highly illustrated: includes over 800 images and line drawings that capture the latest investigative techniques.
- Focused on treatment: key points boxes pick out the most important information for the busy specialist.
- Evidence-based information: extensively referenced with the latest and most important papers and articles.
Specialists in fetal medicine, Neonatologists, General paediatricians, Paediatric neurosurgeons, Paediatric neurologists
SECTION I Structural Development of the CNS
1. The molecular basis of brain development
2. Early embryonic development of the brain
3. Development of consciousness: fetal, neonatal and maternal interactions
4. Ultrasound assessment of normal fetal brain development
5. MR imaging of the fetal central nervous system
6. Imaging the neonatal brain
SECTION II Functional Assessment of CNS Development
7. Functional assessment of the fetal CNS
8. The development of senses
9. Clinical assessment of the infant nervous system
10. Perinatal cerebral circulation
11. Cerebral blood flow and energy metabolism in the developing brain
12. EEG and evoked potentials in the neonatal period
SECTION III Anomalies
13. Congenital structural defects of the brain
14. Genetics of neurodevelopmental anomalies
15. Antenatal assessment of CNS anomalies, including neural tube defects
16. Transvaginal fetal neuroscan
17. Epidemiology and prevention of neural tube defects
SECTION IV Hemorrhagic and Ischemic Lesions
18. Fetal brain injury and multiple pregnancies
19. Infection, inflammation and brain injury
20. Neonatal intracranial hemorrhage
21. Cerebral ischemic lesions
SECTION V Perinatal Asphyxia
22. Pathophysiology of asphyxia
23. Antenatal prediction of asphyxia
24. Intrapartum monitoring for asphyxia
25. Prediction of asphyxia with fetal gas analysis
26. The asphyxiated newborn infant
27. Neuroprotection of the fetal and neonatal brain
28. Medico-legal issues: The United Kingdom perspective
29. Malpractice issues in perinatal medicine: The United States perspective
SECTION VI Infection of the CNS
30. Toxoplasmosis
31. Congenital viral infections and the central nervous system
32. Bacterial and fungal infections
SECTION VII Metabolic Disorders
33. Inborn errors of metabolism presenting with encephalopathy
SECTION VIII Seizure Disorders
34. Seizure disorders of the neonate
35. Hypoglycemia and brain injury - when neonatal metabolic adaptation fails
36. Kernicterus
SECTION IX the Special Senses
37. Disorders of vision
38. Hearing disorders
SECTION X Disorders of the Nerve and Muscle
39. Disorders of the spinal cord, cranial and peripheral nerves
40. Neuromuscular disorders
SECTION XI Hydrocephalus and Neurosurgery
41. Fetal neurosurgical interventions
42. Neonatal hydrocephalus – clinical assessment and non-surgical treatment
43. Neurosurgical management of hydrocephalus
44. Surgical management of neural tube defects
45. Congenital defects, vascular malformations and other lesions
SECTION XII Epidemiology of Neurologic Disability
46. The epidemiology of the cerebral palsies
47. The epidemiology of intellectual disabilities
SECTION XIII Ethical Dilemmas
48. Issues for the obstetrician
49. Issues for the neonatologist
1. The molecular basis of brain development
2. Early embryonic development of the brain
3. Development of consciousness: fetal, neonatal and maternal interactions
4. Ultrasound assessment of normal fetal brain development
5. MR imaging of the fetal central nervous system
6. Imaging the neonatal brain
SECTION II Functional Assessment of CNS Development
7. Functional assessment of the fetal CNS
8. The development of senses
9. Clinical assessment of the infant nervous system
10. Perinatal cerebral circulation
11. Cerebral blood flow and energy metabolism in the developing brain
12. EEG and evoked potentials in the neonatal period
SECTION III Anomalies
13. Congenital structural defects of the brain
14. Genetics of neurodevelopmental anomalies
15. Antenatal assessment of CNS anomalies, including neural tube defects
16. Transvaginal fetal neuroscan
17. Epidemiology and prevention of neural tube defects
SECTION IV Hemorrhagic and Ischemic Lesions
18. Fetal brain injury and multiple pregnancies
19. Infection, inflammation and brain injury
20. Neonatal intracranial hemorrhage
21. Cerebral ischemic lesions
SECTION V Perinatal Asphyxia
22. Pathophysiology of asphyxia
23. Antenatal prediction of asphyxia
24. Intrapartum monitoring for asphyxia
25. Prediction of asphyxia with fetal gas analysis
26. The asphyxiated newborn infant
27. Neuroprotection of the fetal and neonatal brain
28. Medico-legal issues: The United Kingdom perspective
29. Malpractice issues in perinatal medicine: The United States perspective
SECTION VI Infection of the CNS
30. Toxoplasmosis
31. Congenital viral infections and the central nervous system
32. Bacterial and fungal infections
SECTION VII Metabolic Disorders
33. Inborn errors of metabolism presenting with encephalopathy
SECTION VIII Seizure Disorders
34. Seizure disorders of the neonate
35. Hypoglycemia and brain injury - when neonatal metabolic adaptation fails
36. Kernicterus
SECTION IX the Special Senses
37. Disorders of vision
38. Hearing disorders
SECTION X Disorders of the Nerve and Muscle
39. Disorders of the spinal cord, cranial and peripheral nerves
40. Neuromuscular disorders
SECTION XI Hydrocephalus and Neurosurgery
41. Fetal neurosurgical interventions
42. Neonatal hydrocephalus – clinical assessment and non-surgical treatment
43. Neurosurgical management of hydrocephalus
44. Surgical management of neural tube defects
45. Congenital defects, vascular malformations and other lesions
SECTION XII Epidemiology of Neurologic Disability
46. The epidemiology of the cerebral palsies
47. The epidemiology of intellectual disabilities
SECTION XIII Ethical Dilemmas
48. Issues for the obstetrician
49. Issues for the neonatologist
- No. of pages: 944
- Language: English
- Edition: 4
- Published: April 10, 2014
- Imprint: Churchill Livingstone
- eBook ISBN: 9780702050503
FC
Frank A. Chervenak
Affiliations and expertise
Given Foundation Professor and Chairman, Department of Obstetrics and Gynecology, New York Weill Cornell Medical Center, New York, NY, USA
Given Foundation Professor and ChairmanML
Malcolm I. Levene
Malcolm Levene MD, FRCP, FRCPCH, FMedSc
retired Professor of Paediatrics and Child Health, University of Leeds, Leeds General Infirmary Leeds
Affiliations and expertise
Professor of Pediatrics and Child Health, Division of Paediatrics and Child Health, University of Leeds, Leeds General Infirmary, Leeds, UK