LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurologi… Read more
LIMITED OFFER
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease.
Neuroscientists, geriatricians, neurobiologists, experimental biologists, clinicians, graduate students, and post-doctoral fellows
Part IGenetics, Molecular and Cellular Biology
1. Genetics of frontotemporal dementiaEbru Erzurumluoglu Gokalp, Demet Adapinar and Sevilhan Artan
2. Aging, brain-derived neurotrophic factor (BDNF) and its polymorphismTing Shen, Yuyi You, Vivek K. Gupta and Stuart L. Graham
3. Aging, demented patients, and polymorphisms in cytokine genesVanêssa Gomes Fraga, Paulo Caramelli and Karina Braga Gomes
4. RNA fragments and brain agingLingyu Guan and Andrey Grigoriev
5. Centrosome functions and remodeling during neuronal development and centrosome abnormalities in neuronal disorders, disease, and in agingHeide Schatten
6. Brain aging and microarray analysisCristina Sanfilippo and Michelino Di Rosa
7. Human nuclear tau and agingConcetta Federico, Francesca Bruno, Valentina Sturiale, Agata Grazia D’Amico, Grazia Maugeri, Velia D’Agata, Laura Gil and Salvatore Saccone
8. Lipoxidation: features, neurological tissues and agingReinald Pamplona, Mariona Jové, Irene Pradas, Natalia Mota-Martorell and Isidro Ferrer
9. Aging modifies concentration and metabolism of amino acids and associated receptor functionality in the brain Mitsuhiro Furuse
10. How 3’,5’-cyclic nucleotide phosphodiesterases change in the brain with normal aging and dementiaMichy Kelly
11. The prohibitin complex in aging and neurodegenerationAndrea González-Morales, Mercedes Lachén-Montes, Karina Ausin, Paz Cartas-Cejudo, Naroa Mendizuri, Joaquín Fernández-Irigoyen and Enrique Santamaría
12. Synaptic ATPase and energy metabolism in the nervous system: roles and changes in the aging processRoberto Villa and Federica Ferrari
Part IINeurological and Imaging Features
13. Microstructural Imaging of the Human Brain with Normal and "Abnormal" Aging using Diffusion Magnetic Resonance ImagingYu-Chien Wu
14. Imaging the brain and its vascular in aging: applications of optical coherence tomography angiographyRuikang K. Wang and Yuandong Li
15. Potential involvement of perineuronal nets in brain aging: an anatomical point of viewJun Yamada and Shozo Jinno
16. Grey-matter networks in agingMarisa Koini
17. Changes in brain synapse-related molecules with ageKiyohito Mizutani and Yoshimi Takai
18. Macroautophagy and chaperone-mediated autophagy in agingTando Maduna, Andre du Toit and Ben Loos
19. Neuronal L-type calcium channels in agingJoanne Koh, Sheeja Navakkode, Jing Zhai and Tuck Wah Soong
20. The impact of aged microglia on D-serine-regulated glutamatergic transmissionSebastián Beltrán-Castillo, Rommy von Bernhardi and Jaime Eugenín
21. Ion channels and the aging brainFederico Sesti and Alessandro Bortolami
22. Dendritic spine remodeling and agingBenjamin D. Boros and Jeremy H. Herskowitz
23. High-density lipoprotein-cholesterol and neuroaging: memory and gyrification of the insular and frontal opercular cortexRyuta Kinno and Kenjiro Ono
24. Astrocyte and microglial aging: morphology and modelingTiffany A. Peterson and Andrew G. MacLean
25. Cerebellum - aging of the neuronal machinePavel Filip and Martin Bare
26. Lipids, beta-secretase 1, and Alzheimer diseaseJ. Villamil-Ortiz, B.J.L. Eggen and G.P. Cardona-Go´mez
27. Aging, myelination and the optic nerveAhmed Abdellatif and Hamdino Attia
28. Linking proteostasis, aging, and brain ischemiaWei Yang, Ran Li, Xuan Li and Dennis A. Turner
29. Luteinizing hormone and the aging nervous systemMegan Mey and Gemma Casadesus
30. Insights into aging using transcranial magnetic stimulationJennifer I. Lissemore, Lauren Wengle, Zafiris J. Daskalakis and Daniel M. Blumberger
31. Alpha rhythms: what they are and how they alter with agingMaria Knyazeva
32. Nicotine and its derivatives in healthy brain agingAlireza Majdi and Saeed Sadigh-Eteghad
Part IIIPhysiological Aspects
33. Environmental enrichment and physiological agingYulia K. Komleva, Vladimir V. Salmin, Olga L. Lopatina, Olga A. Belova and Alla B. Salmina
34. Treadmill exercise and neuroinflammation: links with agingCaroline Cristiano Real, Karina Henrique Binda and Anne Marlene Landau
35. Impact of aerobic exercise on brain structure in models of aging: hippocampus and beyondLars Stiernman Jonasson, Chelsea Stillman and Kirk I. Erickson
36. The effects of cardiorespiratory fitness on brain and cognitive agingDaniel C. Bowie, Grace M. Clements, Gabriele Gratton and Monica Fabiani
37. Aging, babble noise, and the processing of speech perceptionHanani Abdul Manan, Noorazrul Azmie Yahya and Ahmad Nazlim Yusoff
38. The blood-brain barrier in agingLuca Anna Bors and Franciska Erdő
Part IVBehavior And Psychopathological Aspects
39. Linking aging, anticholinergic drug use, and cognitive impairmentMariangela Boccardi and Virginia Boccardi
40. Cognitive Frailty: Definitions, components and impact on disability, and mortalityFrancesco Panza, Maddalena La Montagna, Vincenzo Solfrizzi, Rodolfo Sardone, Vittorio Dibello, Antonello Bellomo, Antonio Greco, Antonio Daniele, Davide Seripa, Gianluigi Giannelli and Madia Lozupone
41. Cognitive impairment (brain) and (et) dynapenia (D) “BED” in older persons: role of arterial treeMarcello Maggio and Fulvio Lauretani
42. Disentangling the effects of aging and ovarian hormone loss on sleep: implications for health and diseaseGina Nicoll, Anne Almey and Nicole J. Gervais
43. Role of DNA methylation in aging-related cognitive functioningAnna Starnawska and Nicklas Heine Staunstrup
44. Depression in the elderly and psychobioticsElnaz Vaghef-Mehrabany, Mehrangiz Ebrahimi-Mameghani, Mahzad Sanayei and Leila Vaghef-Mehrabany
Part VDiet And Nutrition
45. Aging, dietary patterns and cognitionAngela Marie Abbatecola and Raffaele Marfella
46. Geriatric nutritional risk index: applications and limitationsMahzad Sanayei, Elnaz Vaghef-Mehrabany and Leila Vaghef-Mehrabany
47. Diet, inflammation, and neurocognitive agingYian Gu
48. The dietary approaches to stop hypertension (DASH) and Mediterranean-DASH intervention for neurodegenerative delay (MIND) diets and brain agingSamantha L. Gardener and Stephanie R. Rainey-Smith
49. The ketogenic diet and healthy brain agingGeorgia A.F. Rogerson and Victor R. Preedy
50. Autophagy and aging: diet, exercise, and the link with the target of rapamycin complex 1 (TORC)Kurt A. Escobar and Trisha A. VanDusseldorp
51. Dietary Flavonoids and Brain Health in Ageing: food for ThoughtCatarina Rendeiro and Justin S. Rhodes
52. Antioxidant effects of curcumin and neuroagingShameemah Abrahams, Katelyn Cuttler, Minke Bekker, Jonathan Carr, Soraya Bardien and Okobi Ekpo
53. Lipoic acid and vitamin D3 and their use in preventing brain agingFrancesca Uberti, Sara Ruga, Vera Morsanuto, Mahitab Farghali and Claudio Molinari
54. Effects of β>hydroxy-β-methyl>butyrate (HMB) supplementation on biomarkers for cognitive function and electrophysiological processes in agingAmogh Belagodu, Shuo Kang, Joshua M. Gulley and Roberto Galvez
55. Hydration, the brain, and agingAgata Białecka-Debek
CR
VP
RR
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.