Essential and Toxic Element
Trace Elements in Human Health and Disease
- 1st Edition - January 28, 1976
- Imprint: Academic Press
- Editor: Ananda S. Prasad
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 5 6 4 2 0 2 - 6
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 4 4 9 5 - 2
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 6 2 0 7 - 9
Trace Elements in Human Health and Disease, Volume II: Essential and Toxic Elements is a collection of papers presented at an international symposium on trace elements held in… Read more
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Request a sales quoteTrace Elements in Human Health and Disease, Volume II: Essential and Toxic Elements is a collection of papers presented at an international symposium on trace elements held in Detroit, Michigan on July 10-12, 1974. The symposium provided a forum for discussing the role of essential and toxic elements such as magnesium and chromium in human health and disease. Comprised of 21 chapters, this volume begins with an overview of magnesium deficiency and magnesium toxicity in humans, followed by an analysis of magnesium deficiency and its relation to calcium, parathyroid hormone, and bone metabolism. The reader is then introduced to the biochemistry and physiology of magnesium, along with chromium metabolism and its biochemical effects on humans. Subsequent chapters deal with the metabolism and biochemistry of selenium and sulfur; the health and disease implications of selenium and glutathione peroxidase; effect of pre-eruptive or post-eruptive fluoride administration on caries susceptibility in the rat; and perinatal effects of trace element deficiencies. The book also considers the basis of recommended dietary allowances for trace elements before concluding with a description of quantitative measures of the toxicity of mercury in humans. This book will be useful to physicians, researchers, nutritionists, and toxicologists.
List of Contributors
Preface
Contents of Volume I
26 Magnesium Deficiency and Magnesium Toxicity in Man
I. Introduction
II. Magnesium Deficiency
III. Magnesium Intoxication
IV. Summary
References
27 Magnesium Deficiency and Calcium and Parathyroid Hormone Interrelations
I. Introduction
II. Experimental Symptomatic Magnesium Deficiency in Man
III. Observations in Other Species
IV. Interrelationships among Magnesium, Calcium, Parathyroid Hormone, and Bone Metabolism
V. In Vitro Studies Relating Magnesium to Parathyroid Gland Activity
VI. Effect of Parathyroid Extract in Vivo
VII. Conclusion
References
28 Biochemistry and Physiology of Magnesium
I. Introduction
II. Biochemistry of Magnesium
III. Physiology of Magnesium
IV. Research Needs
References
29 Chromium Metabolism in Man and Biochemical Effects
I. Introduction
II. Role and Structure of Glucose Tolerance Factor (GTF)
III. Evidence for Chromium Deficiency in Animals and Man
IV. Chromium Content of the Diet
V. Absorption, Transport, and Excretion of Chromium
VI. Biological Effects of GTF Supplementation of the Diet
VII. Unsolved Problems and Research Needs
VIII. Summary
References
30 Selenium in Man
I. Introduction
II. Dietary Intake
III. Metabolism
IV. Tissue Levels
V. Deficiency
VI. Toxicity
VII. Medical Applications
VIII. Assessment of Selenium Status
IX. Research Needs
Addendum
References
31 Selected Aspects of the Comparative Metabolism and Biochemistry of Selenium and Sulfur
I. Introduction
II. Comparative Metabolism of Selenium and Sulfur
III. Comparative Biochemistry of Selenium and Sulfur
IV. Research Needs
References
32 Selenium and Glutathione Peroxidase in Health and Disease—A Review
I. Introduction
II. Properties of Glutathione Peroxidase
III. Assay of Glutathione Peroxidase
IV. Distribution of Glutathione Peroxidase
V. Cellular Functions of Glutathione Peroxidase
VI. Glutathione Peroxidase in Human Diseases
VII. Research Needs
References
33 Metabolism and Function of Manganese
I. Introduction
II. Metabolism of Manganese
III. Biochemical and Physiological Changes Associated with Manganese Deficiency
IV. Biochemical Function of Manganese
V. Summary and Conclusions
References
34 Fluoride Metabolism—Effect of Preeruptive or Posteruptive Fluoride Administration on Rat Caries Susceptibility
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
VI. Summary
References
35 Methodology of Trace Element Research
I. Introduction
II. Trace Element Diversity and Characteristics
III. The Essential Elements
IV. Naturally Occurring “Area” Problems with Trace Elements
V. Methodological Problems with Purified and Special Diets
References
36 Mineral Interrelationships
I. Introduction
II. Interaction of Trace Elements
III. Research Needs
References
37 Perinatal Effects of Trace Element Deficiencies
I. Introduction
II. Copper
III. Manganese
IV. Zinc
V. Magnesium
VI. Conclusion
References
38 Effects of Oral Contraceptive Agents on Trace Element Metabolism—A Review
I. Introduction
II. Oral Contraceptives and Trace Element Metabolism
III. Future Research Needs
References
39 Human Intake of Trace Elements
I. Introduction
II. Diet in the Trace Element Deficiency of Egyptians
III. Research Needs
References
40 Basis of Recommended Dietary Allowances for Trace Elements
I. Introduction
II. What Is a Recommended Dietary Allowance?
III. Considerations in Setting RDA
IV. RDA for Trace Elements
V. Need for More Knowledge on Which to Base RDA
References
41 Newer Trace Elements and Possible Application in Man
I. Introduction
II. Review and Discussion
III. Research Needs
References
42 Cadmium Metabolism—A Review of Aspects Pertinent to Evaluating Dietary Cadmium Intake by Man
I. Introduction
II. Present Knowledge of Cadmium Metabolism
III. Research and Information Needs
References
43 Review of Hypertension Induced in Animals by Chronic Ingestion of Cadmium
I. Introduction
II. Review of Hypertension Induced by Cadmium Feeding
III. Discussion
IV. Conclusions
References
44 The Chronic Toxicity of Cadmium
I. Introduction
II. Effects of Cadmium
III. Needs for Further Research
References
45 Metabolism and Toxicity of Lead
I. Introduction
II. Sources of Lead
III. Metabolic Effects
IV. Clinical Symptoms
V. Screening Methods
VI. Interaction with Other Nutrients
VII. Summary
References
46 Quantitative Measures of the Toxicity of Mercury in Man
I. Introduction
II. Dose-Response Relationships in Human Populations Exposed to Elemental Mercury Vapor or Methylmercury Compounds
III. Factors Affecting the Toxicity of Mercury in Man
IV. Research Needs
V. Summary
References
Author Index
Cumulative Subject Index
- Edition: 1
- Published: January 28, 1976
- Imprint: Academic Press
- No. of pages: 534
- Language: English
- Hardback ISBN: 9780125642026
- Paperback ISBN: 9781483244952
- eBook ISBN: 9781483262079
AP
Ananda S. Prasad
Dr. Ananda Prasad was the first scientist to recognize the essentiality of zinc for human health and to recognize that zinc deficiency is a common problem globally in 1963. This led the US Congress to declare zinc as an essential nutrient for human health, and in 1974, the National Academy of Sciences established recommended dietary allowances for zinc. He has received many awards and honors for this discovery, including a Goldberger Award from the American Medical Association, an Outstanding Research Award from American College of Physicians, the Mahidol Award from the Kind of Thailand, the Medal of Honor from the Mayor of Lyon in France, and an Honorary Doctorate from the Claude Bernard University in Lyon. He has published over 300 papers and 15 books and is the founder and emeritus editor of the American Journal of Hematology.
Affiliations and expertise
Distinguished Professor, Department of Oncology, Wayne State University School of MedicineRead Essential and Toxic Element on ScienceDirect