
Epilepsy and Brain Tumors
- 1st Edition - March 4, 2015
- Imprint: Academic Press
- Editors: Herbert B. Newton, Marta Maschio
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 4 1 7 0 4 3 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 4 1 7 1 2 6 - 8
Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been re… Read more

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Request a sales quotePatients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues.
- Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors
- Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more
- Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available
Clinical neurologists, neuroscience researchers, clinically practicing neurosurgeons, neurologists, neuro-oncologists, epileptologists
- Dedication
- Foreword
- Preface
- Chapter 1: Brain Tumor-Related Epilepsy: Introduction and Overview
- Abstract
- Introduction
- Epilepsy: Definition, Incidence, Social Context and Treatment Options
- Chapter 2: Overview of Epidemiology, Pathology, and Treatment of Primary Brain Tumors
- Abstract
- Acknowledgments
- Epidemiology of PBT
- Pathology of Selected PBT
- Surgical Therapy of PBT
- Radiation Therapy of PBT
- Chemotherapy of PBT
- Molecular or “Targeted” Treatment
- Chapter 3: Overview of Epidemiology, Pathology, and Treatment of Metastatic Brain Tumors
- Abstract
- Acknowledgments
- Epidemiology of MBTs
- Pathology of MBTs
- Surgical Therapy of MBTs
- Radiation Therapy of MBTs
- Chemotherapy of MBTs
- Chapter 4: Supportive Care of Brain Tumor Patients
- Abstract
- Introduction
- Seizures and Anticonvulsant Therapy
- Corticosteroids
- Gastric Acid Inhibitors
- Thromboembolic Complications and Anticoagulation
- Dysphagia and Swallowing Disorders
- Psychiatric Issues
- Pain Control Issues
- Palliative Care
- Ethical Issues
- Conclusion
- Chapter 5: Brain-Tumor-Related Epilepsy in Children
- Abstract
- Acknowledgment
- The Pediatric Perspective
- Epilepsy-Associated Brain Tumors
- Pathophysiology
- Epidemiology
- Presentation
- General Principles of Management
- History and Physical Exam
- Diagnostic Evaluation
- Medical Management
- Surgical Management
- Outcome
- Future Directions
- Chapter 6: Mechanisms of Focal Epileptogenesis
- Abstract
- Time Course and Specificity of Acquired Epileptogenesis
- Chapter 7: Pathophysiology of Brain Tumor-Related Epilepsy
- Abstract
- Introduction
- Epidemiology of BTRE
- Pathophysiology of BTRE
- Treatment of BTRE
- Chapter 8: The Neurophysiology of Central Nervous System Tumors
- Abstract
- Introduction
- EEG Modalities and Applications
- EEG Background Changes
- Epileptiform Activity
- Meningiomas
- Generation of Abnormal Cerebral Activity
- Chapter 9: Surgical Treatment for Epilepsy
- Abstract
- Introduction
- Evaluation and Selection of the Surgical Candidate
- Resection Procedures
- Nonresective Techniques
- Disconnection Surgeries
- Chapter 10: Clinical Evaluation of Epilepsy in the Brain-Tumor Patient
- Abstract
- Acknowledgments
- Differential Diagnosis
- Clinical History and Physical Examination
- Neuroimaging Evaluation
- Clinical and Electrophysiological Work-Up
- Effects of Oncological Therapy on Brain Tumor-Related Epilepsy
- Chapter 11: Antiepileptic Drugs: First Generation
- Abstract
- Carbamazepine
- Ethosuximide
- Phenobarbital
- Phenytoin
- Primidone
- Valproate
- Chapter 12: Antiepileptic Drugs: Second and Third Generation
- Abstract
- Introduction
- Clobazam
- Eslicarbazepine Acetate
- Ezogabine/Retigabine
- Felbamate
- Gabapentin
- Lacosamide
- Lamotrigine
- Levetiracetam
- Oxcarbazepine
- Perampanel
- Pregabalin
- Rufinamide
- Tiagabine Hydrochloride
- Topiramate
- Vigabatrin
- Zonisamide
- Chapter 13: Antiepileptic Drugs and Brain Tumor Patients
- Abstract
- Introduction
- Pathophysiology
- Type of Seizure
- Treatment of Seizures
- Levetiracetam
- Oxcarbazepine
- Lacosamide
- Pregabalin
- Topiramate
- Zonisamide
- Lamotrigine
- Conclusion
- Chapter 14: Clinical Approach to Brain Tumor-Related Epilepsy
- Abstract
- Seizure Prophylaxis in Patients with BTRE
- Is There a Best Practice for Seizure Treatment?
- Clinical Approach to BTRE
- Driving and BTRE
- Chapter 15: Neuropsychology of BTRE
- Abstract
- Introduction
- Overview of Neurocognitive Impairment in BT, Epilepsy, and BTRE
- Neurocognitive Impairment in BTRE
- Specific Cognitive Deficits in BT, Epilepsy, and BTRE
- Overview of Neuropsychological Assessment Techniques for BT, Epilepsy, and BTRE
- Psychological Issues in BT, Epilepsy, and BTRE
- Sexual Disturbances in Patients with BT, Epilepsy and BTRE
- QoL Assessment and Monitoring in BT, Epilepsy and BTRE
- Conclusions
- Chapter 16: Cognitive Rehabilitation in Patients with BTRE
- Abstract
- Introduction
- Goals of Cognitive Rehabilitation
- Treatment Modalities in BT
- Treatment Modalities in Epilepsy
- Treatment Modalities in BTRE
- Pharmacological Approaches for Treatment of Cognitive Deficits
- Caregivers Issues
- Implications for Future Research in BTRE
- Chapter 17: Social Cost of Brain Tumor-Related Epilepsy
- Abstract
- Introduction
- Health Economic Reporting: Terminology and Aims
- Health Economics: Funding Priorities
- Epilepsy
- Brain Tumor
- Conclusion
- Appendix: The Prospects of Brain Research within Horizon 2020: Responding Efficiently to Europe’s Societal Needs European Parliament, Brussels May 30th, 2013
- Summary
- Index
- Edition: 1
- Published: March 4, 2015
- Imprint: Academic Press
- No. of pages: 292
- Language: English
- Hardback ISBN: 9780124170438
- eBook ISBN: 9780124171268
HN
Herbert B. Newton
MM
Marta Maschio
In addition to her clinical work, Dr. Maschio is an active researcher and has published over 100 articles on BTRE and numerous book chapters. She also contributed to the development of BTRE Treatment Recommendations published in 2008, as member of the Italian Scientific Committee, designated by the Italian Association for Neuro-oncology. Since 2011, she has been Co-Director of the Neuro-oncological Section, International School of Neurological Science S. Servolo, Venice International University, and since 2012, is National Coordinator of the BTRE Study Group, Italian Society against Epilepsy.
In 2010, she created her Centers’ web portal, the first in the world exclusively for BTRE patients, of which she is very proud.
On a personal note, she has also won several national poetry awards.