Encyclopedia of Hereditary Cancer
A Desktop Reference
- 1st Edition - June 13, 2024
- Imprint: Academic Press
- Author: John W. Henson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 5 7 5 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 5 7 6 - 7
Encyclopedia of Hereditary Cancer: A Desktop Reference gives insights into this young and rapidly expanding field that combines oncology and genetics to achieve risk reduction… Read more
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Request a sales quoteEncyclopedia of Hereditary Cancer: A Desktop Reference gives insights into this young and rapidly expanding field that combines oncology and genetics to achieve risk reduction, early detection, family risk management, and identification targeted treatments. While genetics and oncology are both well-developed knowledge areas, their combination in hereditary cancer yields an opportunity for new works that systemize knowledge for current researchers, practitioners, and students. The book exams 371 topics through the lens of hereditary cancer. There are no similar books that presents information in this manner.
This reference work contains a complete list of terms and definitions which can be easily reference by researchers and clinicians working in this field.
- Provides conceptual and factual treatments of 371 topics in hereditary cancer
- Gives quick access to a comprehensive guide on Hereditary Cancer
- Useful reference for researchers and clinicians
Clinicians, oncologists, cancer researchers, geneticists, researchers with an interest in hereditary cancer and cancer genetics, genetic counselors, cancer surgeons, neuro-oncologists, gastroenterologists, internists, and family practitioner
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Quote
- Foreword
- Acknowledgments
- Abbreviations
- Inside front cover
- Introduction
- A
- Activating variant
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Allele
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Allele frequency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Allelic disorder
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Allelic dropout
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Allelic imbalance
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Alteration/Variant/Mutation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Alu repeat
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Amino acid
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Amplicon
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Aneuploidy
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Angiomyolipoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Anticipation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- APOBEC
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Aspirin
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Autosomal dominant inheritance
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Autosomal recessive inheritance
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Autosomal recessive hereditary cancers
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Autosomes and allosomes
- B
- BAP1 tumor predisposition syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Beckwith–Wiedemann spectrum
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Biallelic mutations
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Birt–Hogg–Dube syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Breast cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Breast tissue density
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- C
- Carcinoma of unknown primary
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Carney complex
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Cascade testing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Cell-free DNA
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Checkpoint inhibitor
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Chromatin
- Chromatin remodeling
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Chromosomal microarray
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Chromosomes
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Clonal expansion
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Colorectal cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Compound heterozygote
- Consanguinity
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Constitutional mismatch repair deficiency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Contiguous gene deletion syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Copy number alteration
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- CpG island methylator phenoytpe
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- CpG island
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Cystic fibrosis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- D
- Deamination
- De novo variant
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Desmoid
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- DICER1 tumor predisposition syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Digenic modifier
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- DNA—amplification
- DNA damage and repair
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- DNA glycosylase
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- DNA—methylation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- DNA—mitochondrial
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- DNA replication
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Dominant negative
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Double heterozygote
- Double minute
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Down syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Driver mutations and passenger mutations
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Dyskeratosis congenita
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Dysmorphology
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- E
- Embryonic lethal
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Endometrial carcinoma
- Epimutation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- F
- Familial and heritable
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Familial adenomatous polyposis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Familial atypical multiple mole melanoma syndrome
- Familial isolated pituitary adenoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Fanconi anemia
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Food and Drug Administration label
- I Concept
- II Implications in hereditary cancer
- III Technical aspects
- IV Cross-referenced concepts
- Reference
- Founder effect
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- G
- Gain of function and loss of function
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Gamete
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Gastric adenocarcinoma and proximal polyposis of the stomach
- Gastric cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Gastroenteropancreatic tumors
- Gene amplification
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Gene conversion
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Gene dosage
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Gene fusion
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Genetic code
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Genetic conditions with minor cancer risk
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Genetic Information Nondiscrimination Act
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Germline indication
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Glomus tumor—head and neck
- Gonadal mosaicism
- Gorlin syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- H
- Hamartoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Haploid
- Haploinsufficiency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hemangioblastoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hemizygous
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Hereditary breast and ovarian cancer syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hereditary diffuse gastric cancer
- Hereditary leiomyoma and renal cell cancer syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hereditary paraganglioma-pheochromocytoma syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Heterozygous, homozygous
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Human genome variation society nomenclature
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Histone
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Homologous recombination repair deficiency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hotspot
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Hypermutator
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- I
- Immunohistochemistry
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Imprinting
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Inactivating variant
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- J
- Juvenile polyposis syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- K
- Kataegis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- L
- Legius syndrome
- Li–Fraumeni syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Limitations of reports
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Liquid biopsy
- Long interspersed elements
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Loss of function
- Loss of heterozygosity
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Lynch syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Lyonization
- M
- Macrocephaly
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Mastectomy
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Maternal to zygotic transition
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Medullary thyroid cancer
- Meiosis
- Melanoma—hereditary
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Metanephrines
- Microdeletion
- Microsatellite instability
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Minor allele frequency
- Minor allele frequency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- References
- Missense variant
- Mitosis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- MLH1 promoter methylation—constitutional
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Monogenic disorder
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Mosaicism
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Multiple endocrine neoplasia type 1
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Multiple endocrine neoplasia type 2
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Mutation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Mutation signature
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- MUTYH-associated polyposis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- N
- National Comprehensive Cancer Network
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Neurofibromatosis type 1
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Neurofibromatosis type 2
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Nevoid basal cell carcinoma syndrome
- Next-generation sequencing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Neuroendocrine tumor
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Noninvasive prenatal testing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Nonsense-mediated decay
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Nonsense variant
- NTHL1 tumor syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- O
- Oncogene
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Open reading frame
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Ovarian cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- P
- Paired tumor-germline testing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Pancreas cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Pancreatitis
- Paraganglioma
- Parent-of-origin effect
- Pathogenic variant
- Perivascular epithelioid cell neoplasm
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Pedigree
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Penetrance and expressivity
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Peutz–Jeghers syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Phasing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Phenocopy
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Pheochromocytoma
- Polyadenylation
- Polygenic risk score
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Polymerase proofreading-associated polyposis syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Polymorphism
- Polyposis—gastrointestinal
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- POT1 tumor predisposition syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Preimplantation genetic testing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Premature termination codon
- Proband
- Prostate cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Pseudogene
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Pseudoautosomal region
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- PTEN hamartoma tumor syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- R
- Radiation—ionizing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Receptor tyrosine kinase
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Red flags
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Reduction to homozygosity
- Reference sequence
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Renal cell carcinoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Reportable variants
- Residual risk
- Retinoblastoma
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Reversion mutation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Rhabdoid tumor predisposition syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Risk assessment models
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- RNA-induced silencing complex
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- RNA modifications
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Robertsonian translocation
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- S
- Sex chromosomes
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Simplex case
- Single-base substitutions
- Single nucleotide polymorphism
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Splicing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Surveillance
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Syndromic
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Synthetic lethality
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- T
- Telomere
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Tissues for testing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Thyroid cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Transcriptional interference and silencing
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Tuberous sclerosis complex
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Tumor mutation burden
- Tumor suppressor gene
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Two-hit hypothesis—Knudson
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- U
- Uniparental disomy
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Uterine cancer
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- V
- Variant allele frequency
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Variant analysis
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- Variant classification
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- Reference
- Variant of uncertain significance
- Vestibular schwannoma
- Von Hippel-Lindau Syndrome
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- W
- Wilms tumor predisposition
- I Concept
- II Implications in hereditary cancer
- III Therapeutic considerations
- IV Technical aspects
- V Cross-referenced concepts
- References
- X and Z
- X-inactivation
- Zygote
- Bibliography
- Index
- Edition: 1
- Published: June 13, 2024
- Imprint: Academic Press
- No. of pages: 460
- Language: English
- Hardback ISBN: 9780443135750
- eBook ISBN: 9780443135767
JH
John W. Henson
Dr. Henson is director of the Hereditary Cancer Clinic at the Georgia Cancer Center, Medical College of Georgia, Augusta University, in Augusta, Georgia, USA. He has practiced neuro-oncology for over 25 years and is a well-published leader in several related fields, with over 125 papers and book chapters. He attended the Intensive Course in Cancer Genomic Risk Assessment at City of Hope in 2018. He was previously Chief of Oncology Services at Piedmont Healthcare and on the staff of Massachusetts General Hospital and the faculty of Harvard Medical School for 17 years. Dr. Henson is a member of numerous societies, including as an affiliate member of the American College of Medical Genetics.
Affiliations and expertise
Hereditary Cancer Clinic, Georgia Cancer Center, Augusta, GA,USA.Read Encyclopedia of Hereditary Cancer on ScienceDirect