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Emerging Nanotechnologies in Dentistry
2nd Edition - October 30, 2017
Editors: Karthikeyan Subramani, Waqar Ahmed
Hardback ISBN:9780128122914
9 7 8 - 0 - 1 2 - 8 1 2 2 9 1 - 4
eBook ISBN:9780128122921
9 7 8 - 0 - 1 2 - 8 1 2 2 9 2 - 1
Emerging Nanotechnologies in Dentistry, Second Edition, brings together an international team of experts from the fields of materials science, nanotechnology and dentistry to… Read more
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Emerging Nanotechnologies in Dentistry, Second Edition, brings together an international team of experts from the fields of materials science, nanotechnology and dentistry to explain these new materials and their applications for the restoration, fixation, replacement or regeneration of hard and soft tissues in and about the oral cavity and craniofacial region.
New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants). Each chapter has been comprehensively revised from the first edition, and new chapters cover important advances in graphene based materials for dentistry, liposome based nanocarriers and the neurotoxicity of nanomaterials used in dentistry.
Offers a comprehensive professional reference for the subject covering materials fabrication and use of materials for all major diagnostic and therapeutic dental applications: repair, restoration, regeneration, implants and prevention
Focuses in depth on the materials manufacturing processes involved, with emphasis on pre-clinical and clinical applications, use and biocompatibility
Examines the use of novel nanomaterials including graphene in dentistry, exploring how these may best be used
Academics and biomedical engineers working in the areas of nanomedicine, nanomaterials, dentistry and oral health
Cover image
Title page
Table of Contents
Copyright
Dedication
List of Contributors
Foreword
Acknowledgments
Chapter 1. Nanotechnology and its applications in dentistry—An introduction
Abstract
1.1 Introduction
1.2 Nanotechnology Approaches
1.3 Nanotechnology to Nanomanufacturing
1.4 Nanodentistry
1.5 Future Directions and Conclusions
References
Chapter 2. Nanoparticles for dental materials: Synthesis, analysis, and applications
Abstract
2.1 Introduction: Why Use Nanoparticles?
2.2 Synthesis of Nanoparticles
2.3 Examples of Dental Materials Using Nanoparticles
2.4 Selected Properties of Dental Materials Containing Nanoparticles
2.5 Clinical Experience With Dental Materials Containing Nanoparticles
2.6 Conclusions
References
Chapter 3. Antimicrobial nanoparticles in restorative composites
Abstract
3.1 Introduction
3.2 Antibacterial Restorative Composites
3.3 Antimicrobial Macromolecules
3.4 Nanoparticles
3.5 Conclusions
References
Chapter 4. Nanotechnology in operative dentistry: A perspective approach of history, mechanical behavior, and clinical application
Abstract
4.1 Introduction
4.2 Historical Review: Nanotechnology Applications in Operative Dentistry
4.3 Biomimetics
4.4 Nanotechnology in CAD/CAM
4.5 Fillers in Composite Resins
4.6 SEM and EDS Evaluations
4.7 Filler Weight Content (wt%)
4.8 Water Sorption
4.9 Mechanical Behavior
4.10 Clinical Application
4.11 Conclusions
Acknowledgments
References
Chapter 5. Impact of nanotechnology on dental implants
Abstract
5.1 Introduction
5.2 Nanoscale Surface Modifications
5.3 Interactions of Surface Dental Implants With Blood
5.4 Interactions Between Surfaces and MSCs
5.5 Tissue Integration
5.6 Conclusion
Acknowledgments
References
Chapter 6. Titanium surface modification techniques for dental implants—From microscale to nanoscale
Abstract
6.1 Introduction
6.2 Titanium Surface Modification Methods
6.3 Recent Techniques
6.4 Limitations & Conclusion
Acknowledgments
References
Chapter 7. Titanium nanotubes as carriers of osteogenic growth factors and antibacterial drugs for applications in dental implantology
Abstract
7.1 Introduction
7.2 Titanium Nanotubes
7.3 TiO2 Nanotubes for Implant Fabrication
7.4 Functionalization of TiO2 Nanotubes with Growth Factors and Antibacterial/Antiinflammatory Drugs
7.5 Recent Advancements
7.6 Conclusions
References
Chapter 8. Cellular responses to nanoscale surface modifications of titanium implants for dentistry and bone tissue engineering applications
Abstract
8.1 Introduction
8.2 Nanotopography Generated from Surface Modification of Ti Implants
8.3 Nanotopography and Protein Absorption
8.4 Nanotopography Alters Osteoblast Responses
8.5 Nanotopography and Stem Cell Responses
8.6 Conclusions
References
Chapter 9. Corrosion resistance of Ti–6Al–4V with nanostructured TiO2 coatings
Abstract
9.1 Introduction
9.2 Nanostructured TiO2 Deposited on Ti–6Al–4V
9.3 Characterization Techniques
9.4 Corrosion Test With Electrochemical Techniques
11.8 Seeding Bone Marrow Stem Cells on Nanoapatite Scaffolds
11.9 Conclusions
Acknowledgments
References
Chapter 12. Self-assembly of proteins and peptides and their applications in bionanotechnology and dentistry
Abstract
12.1 Introduction
12.2 Mechanism of Molecular Self-Assembly
12.3 Classification of Self-Assembly
12.4 Self-Assembly of Proteins and Peptides
12.5 Bionanotechnology Applications
12.6 Peptide Nanofibers, Nanotubes, and Nanowires
12.7 Three-Dimensional Peptide Matrix Scaffolds
12.8 Advantages and Limitations of Self-Assembling Peptide Matrix Scaffolds
12.9 Self-Assembly in Regenerative Biology and Dentistry
12.10 Conclusions
References
Chapter 13. Surface engineering of dental tools with diamond for enhanced life and performance
Abstract
13.1 Tooth Materials
13.2 Dental Burs
13.3 Chemical Vapor Deposition of Diamond Films Onto Dental Burs
13.4 Bur Performance Investigations
13.5 Conclusions
References
Further Reading
Chapter 14. Nanomechanical characterization of mineralized tissues in the oral cavity
Abstract
14.1 Introduction
14.2 Basic Data Analysis Protocol for Nanoindentation
14.3 Nanoindentation of Oral Mineralized Tissues
14.4 Summary
References
Further Reading
Chapter 15. Nanoindentation techniques for the determination of mechanical properties of materials in dentistry
Abstract
15.1 Introduction
15.2 Basic Information From the Load–Displacement Curves
15.3 Characterization of Inelastic Properties
15.4 Determination of Properties in Nonhomogeneous Bodies
15.5 Characterization of Time-Dependent Load Response
15.6 Resistance Against Crack Propagation
15.7 Scratch Tests for the Evaluation of Friction and Wear Resistance
15.8 Devices for Nanoindentation
Acknowledgments
References
Chapter 16. Nanocharacterization techniques for dental implant development
Abstract
16.1 Measurement of the Topology of Nanostructures
16.2 Measurement of Nanostructure Internal Geometries
16.3 Measurement of Composition of Nanostructures
16.4 Measurement of the Mechanical Properties of Nanostructures
16.5 Conclusions
References
Chapter 17. Nanoparticulate drug-delivery systems for oral cancer treatment
Abstract
17.1 Introduction
17.2 Cancer-Treatment Techniques
17.3 Mechanism of Action of Chemotherapeutic Agents
17.4 Oral Cancer
17.5 TNM Classification of Tumors
17.6 Management of Oral Cancer
17.7 Nanoparticulate-Based Drug Delivery in Cancer Treatment
17.8 Limitations of Nanoparticles and Conclusion
References
Chapter 18. Carbon nanotubes: Applications in cancer therapy and drug delivery research
Abstract
18.1 Introduction
18.2 Cellular Uptake of CNTs
18.3 CNTs as Carriers for Small and Large Drug Molecules
18.4 Carbon Nanotubes for Oral Cancer Therapy
18.5 Conclusion
References
Chapter 19. Nanodiagnostics in microbiology and dentistry
Abstract
19.1 Introduction
19.2 Nanomaterials
19.3 Biomedical Applications of Nanotechnology and Its Limitations
19.4 Nanotechnology Applications in Drug-Delivery Systems, Nanodiagnostics, and Various Other Fields
19.5 Contribution of Microbiology to Nanotechnology
19.6 AFM Imaging of Microorganisms
19.7 Nanoplasmonic Sensors Detecting Live Viruses
19.8 Nanodentistry
19.9 Conclusions
References
Chapter 20. Neurotoxicity of nanomaterials
Abstract
20.1 Introduction
20.2 Possible Dental Nanomaterials
20.3 Neurotoxicity of Dental Nanomaterials
20.4 Future Research Prospects
20.5 Conclusion
Acknowledgments
References
Index
No. of pages: 496
Language: English
Published: October 30, 2017
Imprint: Elsevier
Hardback ISBN: 9780128122914
eBook ISBN: 9780128122921
KS
Karthikeyan Subramani
Assistant Professor of Dental Medicine at Roseman University of Health Sciences, USA. He was the recipient of the prestigious 2006 Andre Schroeder Research Prize from Straumann (Switzerland) for his innovative research findings during his Biomedical Nanotechnology degree program in the United Kingdom. Dr. Subramani was involved in the International Team for Implantology (ITI) funded research projects in Switzerland, the Netherlands and in the USA. He has authored numerous peer-reviewed research papers and review manuscripts and has authored numerous book chapters. He is also the editor of the Elsevier book Nanomaterials in Clinical Dentistry together with Waqar Ahmed.
Affiliations and expertise
College of Dental Medicine, Roseman University of Health Sciences, Henderson, NV, USA
WA
Waqar Ahmed
Professor of Nanotechnology at the University of Lincoln, UK. His research interests include the synthesis of nanomaterials and nanoparticles and their applications in medicine, dentistry and energy applications
Affiliations and expertise
School of Mathematics and Physics, University of Lincoln, Lincoln, UK