Electroanalytical Applications of Quantum Dot-Based Biosensors

1st Edition - May 19, 2021
Imprint: Elsevier
Editor: Bengi Uslu
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 1 6 7 0 - 5
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 3 2 4 0 - 8

Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with novel physical properties. QDs have two components: an inorganic core and an optically active coated shell.… Read more

Electroanalytical Applications of Quantum Dot-Based Biosensors

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Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with novel physical properties. QDs have two components: an inorganic core and an optically active coated shell. Moreover, surface coatings can be applied to QDs to modify the particle as needed for experiments. Hydrophilic coatings prevent leaking of metal cargo from the core, enhancing the solubility in biological contexts and bind molecules, such as receptor–ligands, antibodies, therapeutic, and diagnostic macromolecules for enhanced effects. Their high surface-to-volume ratio allows multiple functional groups to attach onto the surface of the particles at constant surface volume. Silicon-, gallium-, indium-, or germanium-based; cadmium-based; and carbon-based QDs have already been used in many applications, such as imaging probes for the engineering of multifunctional nanodevices. Superior properties of QDs make them an excellent system in technology and biotechnology.

This book describes electroanalytical applications of QD-based nanobiosensors, including brief information about the synthesis and characterization of QDs and basics of electroanalytical methods, followed by QDs in electrochemical biomimetic sensors, QDs in microchips, inorganic materials doped QDs, QD-based electrochemical DNA biosensors, electroluminescence for biomarker analysis using aptamer-based QDs, QD-based photoelectrochemical techniques, enzyme-based nanobiosensors using QDs, QD-based electrochemical immunosensors, and QD-modified nanosensors in drug analysis.

Cover image
Title page
Table of Contents
Copyright
Dedication
Contributors
Preface
Chapter 1: Quantum dots: Synthesis and characterizations
Abstract
1: Introduction
2: Classification of QDs
3: Synthesis of QDs
4: Characterization techniques of QDs
5: Conclusions
Chapter 2: Basics of electroanalytical methods and their applications with quantum dot sensors
Abstract
1: Introduction
2: Electroanalytical methods and their applications with QD sensors
3: Conclusion
Chapter 3: Quantum dots-based sensors using solid electrodes
Abstract
1: Introduction
2: Properties and applications of QDs
3: Solid electrodes and electrode modification techniques via QDs
4: Overview of trends in the construction of sensors with QDs
5: Conclusion
Chapter 4: Quantum dot-based electrochemical molecularly imprinted polymer sensors: potentials and challenges
Abstract
Acknowledgments
1: Introduction
2: Molecularly imprinted polymers
3: QD-based electrochemical sensors
4: QD-based photoelectrochemical sensors
5: Conclusions
Chapter 5: Electrochemical DNA biosensors based on quantum dots
Abstract
1: Introduction
2: Basic electrochemical characteristics of QDs
3: Methods for QD biofunctionalization in sensor systems
4: Types of QDs and their electrochemical applications for DNA biosensing
5: Conclusions and outlook
Chapter 6: Electrochemiluminescent and photoelectrochemical aptasensors based on quantum dots for mycotoxins and pesticides analysis
Abstract
1: Introduction
2: Light and electricity: Electrochemiluminescence and photoelectrochemistry
3: Aptasensors based on quantum dots for food contaminant analysis
4: Conclusions
Chapter 7: Quantum dots-based photoelectrochemical sensors and biosensors
Abstract
Acknowledgements
1: Introduction
2: Photosensitive materials and mechanisms in PEC analysis
3: PEC biosensors
4: Conclusion
Chapter 8: Fabrication of quantum dot-polymer composites and their electroanalytical applications
Abstract
1: Introduction
2: Typical polymers used in QD-polymer composites and their electroanalytical applications
3: Conclusion and future perspectives
Chapter 9: Enzyme-based electrochemical nanobiosensors using quantum dots
Abstract
1: Introduction
2: Generation of enzyme-based electrochemical biosensors
3: Applications of quantum dot-modified electrochemical enzyme-based biosensors
4: Conclusions and future perspectives
Chapter 10: Electrochemical immunosensors based on quantum dots
Abstract
1: Introduction
2: Building blocks of electrochemical immunosensors based on QD
3: Signal amplification strategies
4: Nanocomposites in the construction of QD immunosensors
5: Applications of electrochemical immunosensors based on QD
6: Food, environmental, and agricultural analysis
7: Diagnostic tool for cancer and other disease biomarkers
8: Microorganism and drug analysis
9: Future remarks and conclusions
Chapter 11: Electroanalytical application of quantum dots in microchips
Abstract
1: Introduction
2: Direct applications of QDs in bioanalysis
3: Electrochemical applications of microchips by using quantum dots
Chapter 12: Electrochemical applications of inorganic material-doped quantum dots
Abstract
Acknowledgments
1: Introduction
2: Electrochemical applications of heteroatoms-doped quantum dots
3: Electrochemical applications of metal oxide-doped quantum dots
4: Electrochemical applications of metal nanoparticles-doped quantum dots
5: Conclusions
Chapter 13: Future prospects and concluding remarks for electroanalytical applications of quantum dots
Abstract
1: Introduction
2: Synthesis and characterization of quantum dots
3: Future prospects electroanalytical applications of quantum dots
4: Concluding remarks
Index

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