
Early Nutrition and Long-Term Health
Mechanisms, Consequences, and Opportunities
- 2nd Edition - August 6, 2022
- Imprint: Woodhead Publishing
- Editors: Jose M Saavedra, Anne M. Dattilo
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 3 8 9 - 3
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 4 0 5 - 0
Early Nutrition and Long-Term Health: Mechanisms, Consequences, and Opportunities, Second Edition updates and expands upon the content in the first edition and adds focus on action… Read more

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Request a sales quoteEarly Nutrition and Long-Term Health: Mechanisms, Consequences, and Opportunities, Second Edition updates and expands upon the content in the first edition and adds focus on actionable and modifiable aspects of nutrition that have an impact on long-term health and disease.
Part I examines the associations and the mechanisms of early life nutrition on growth as well as the development of cognitive, metabolic, immune, and dietary patterns and behaviors. Part II reviews the associations and impact of early life nutrition on non-communicable disease as well as their societal and economic impact. Part III focuses on the dietary and nutritional needs and approaches to optimizing the different stages of nutrition, from conception to the second year of life.
Nutritionists, pediatricians, academics with research interest in this area, and food industry and healthcare professionals working in infant/child product and services, as well as students studying related disciplines, will benefit from this updated reference.
- Examines the relation between early life nutrition and long-term health
- Reviews the mechanistic aspects of the impact of diet, nutrition, from conception through the first years of life, on health in later life
- Details the associations and the impact of early life nutrition on growth and development, cognition, immunity, metabolism, and dietary habits and patterns
- Addresses the relationship of early life nutrition and with non-communicable diseases, including allergies, cardiovascular diseases, metabolic conditions, and obesity, as well as approaches to curtail them
- Explores the current societal and economic impact and the potential for interventions to improving nutrition and health
Nutritionists, pediatricians, academics with research interest in this area, and food industry and healthcare professionals working in infant/child product and services, as well as students studying related disciplines
- Cover
- Title page
- Table of Contents
- Copyright
- Contributors
- Foreword
- Part I: Nutrition in early life: Mechanisms and impact on long term health
- Chapter 1: Nutrition in the first 1000 days of life: Society’s greatest opportunity
- Abstract
- 1.1: Introduction
- 1.2: Nutrition and health in today’s global landscape
- 1.3: COVID-19
- 1.4: Nutrition as a determinant of health
- 1.5: The long-term impact of early nutrition
- 1.6: The first 1000 days, a window of opportunity
- 1.7: Investing in early life nutrition
- 1.8: Tackling the challenges to improve early life nutrition
- 1.9: Conclusions
- References
- Chapter 2: Programming long-term health: Maternal and fetal nutritional and dietary needs
- Abstract
- 2.1: Introduction
- 2.2: Periconceptional nutritional and dietary needs
- 2.3: Nutrition during pregnancy
- 2.4: Nutrition during the post-natal period
- 2.5: Conclusions
- 2.6: Future trends and research
- Sources of additional information
- References
- Chapter 3: Long-term health outcomes of breastfeeding
- Abstract
- 3.1: Introduction
- 3.2: Neurodevelopment
- 3.3: Obesity, type 2 diabetes, and cardiovascular risk factors
- 3.4: Allergy and autoimmunity
- 3.5: Malignancies
- 3.6: Conclusions
- 3.7: Future research trends
- Sources of additional information
- References
- Chapter 4: Early nutrition: Effects on infants’ growth and body composition
- Abstract
- 4.1: Introduction
- 4.2: The importance of a life cycle approach for promoting infants and children health
- 4.3: Programming of growth and body composition of term newborn by early nutrition
- 4.4: Early nutrition: Effect on growth and body composition at birth and during weight loss
- 4.5: Body composition in relation to breastfeeding and formula feeding
- 4.6: Early rapid weight gain and other childhood obesity determinants in full-term infants
- 4.7: Role of nutrients intake and human milk bioactive compounds as related to infant growth: What’s new
- 4.8: Influence of early nutrition on preterm infants’ growth and body composition. Preterm infants: Time to refine the target?
- 4.9: Early nutritional determinants of growth and body composition of preterm infants
- 4.10: Growth and body composition of preterm infants’ after discharge
- 4.11: Healthy catch-up growth: The narrow pathway
- 4.12: Conclusions
- 4.13: Future trends and research
- Sources of additional information
- References
- Chapter 5: Early nutrition: Effects of specific nutrient intake on growth, development, and long-term health
- Abstract
- 5.1: Introduction
- 5.2: Proteins
- 5.3: Fats: Long-chain polyunsaturated fatty acids and saturated fats
- 5.4: Folate
- 5.5: Iron
- 5.6: Iodine
- 5.7: Zinc
- 5.8: Summary
- 5.9: Future trends and research
- Sources of additional information
- References
- Chapter 6: Early-life nutrition and neurodevelopment
- Abstract
- 6.1: The developmental origins of health and disease (DOHaD) concept—“In the beginning”
- 6.2: DOHaD, the developing brain, and lifespan brain health
- 6.3: Altered early-life nutrition and the cost to society
- 6.4: Nutrients and early brain development
- 6.5: Mechanisms of long-term dysfunction
- 6.6: Nutrients associated with long-lasting brain outcomes
- 6.7: Choline and other methyl compounds
- 6.8: Preclinical studies of epigenetic alterations by choline status
- 6.9: Other methyl compounds
- 6.10: Preclinical studies for folate and B12
- 6.11: Preclinical studies of epigenetic alterations by LC-PUFAs
- 6.12: Preclinical studies of epigenetic alterations by iodine and zinc
- 6.13: Preclinical studies of epigenetic effects of vitamin A
- 6.14: Preclinical studies of epigenetic effects of vitamin D
- 6.15: Conclusions
- 6.16: Future trends and research
- Sources of additional information
- References
- Chapter 7: Effects of infant allergen/immunogen exposure on long-term health outcomes
- Abstract
- 7.1: Introduction
- 7.2: Mechanisms of sensitization and tolerance to proteins, and timing of introduction of food allergens
- 7.3: Long-term effect on immunologic/allergic response of introduction of allergen/immunogen exposure in early life
- 7.4: Future trends and research needs
- Sources of additional information
- References
- Chapter 8: Eating development in young children: The complex interplay of developmental domains
- Abstract
- 8.1: Introduction
- 8.2: Summary of motor skill development
- 8.3: Summary of cognitive and self-awareness development
- 8.4: Summary of sensory development
- 8.5: Looking at the “whole child”: Putting the science to work
- 8.6: Future trends and additional research needs
- 8.7: Summary
- Sources of additional information
- References
- Chapter 9: Impact of early nutrition on gut microbiota: Effects on immunity and long-term health
- Abstract
- 9.1: Introduction
- 9.2: Composition and stability of the microbiota present in infants from early childhood to adult life
- 9.3: Factors influencing the development of the gut microbiota
- 9.4: Microbiota effects on (long-term) health
- 9.5: Dietary potential to modify gut microbiota
- 9.6: Conclusions
- 9.7: Future trends and research needs
- Sources of further information
- References
- Chapter 10: Linking nutrition to long-term health: Epigenetic mechanisms
- Abstract
- 10.1: Introduction
- 10.2: Developmental programming of long-term health
- 10.3: Contribution of perinatal epigenetic marks to later phenotype epigenetic biomarkers and future health
- 10.4: Conclusion
- 10.5: Future trends and research
- Sources of additional information
- References
- Part II: Early nutrition and development of non-communicable diseases
- Chapter 11: Early life nutrition and its effect on the development of obesity and type-2 diabetes
- Abstract
- 11.1: Introduction
- 11.2: Developmental programming of obesity and T2DM
- 11.3: Role of epigenetics in programming of obesity and T2DM
- 11.4: Role of the gut microbiome in the development of obesity and T2DM
- 11.5: Transgenerational effects
- 11.6: Critical developmental windows and strategies for intervention
- 11.7: Summary
- 11.8: Future trends and research
- Sources of additional information
- References
- Chapter 12: Early nutrition and development of cardiovascular disease
- Abstract
- 12.1: Introduction
- 12.2: Importance of CVD risk reduction in childhood
- 12.3: Childhood nutrition and CVD risk factors
- 12.4: Early nutrition and CVD risk
- 12.5: Dietary recommendations for children
- 12.6: Implementation of dietary recommendations in childhood
- 12.7: Conclusions
- 12.8: Research needs
- Sources of additional information
- References
- Chapter 13: Early nutrition and the development of allergic diseases
- Abstract
- 13.1: Introduction
- 13.2: Maternal diet during lactation and pregnancy
- 13.3: Infant diet—Breastfeeding
- 13.4: Infant diet—Hydrolyzed formula and supplementation
- 13.5: Infant diet—Timing of complementary food introduction
- 13.6: Ongoing controversies regarding early allergen introduction
- 13.7: Infant diet diversity
- 13.8: Conclusion
- 13.9: Future trends and research
- Sources of additional information
- References
- Chapter 14: Early nutrition and its effect on the development of celiac disease
- Abstract
- 14.1: Celiac disease
- 14.2: Early nutrition and the risk of celiac disease
- 14.3: Conclusions
- 14.4: Future trends and research
- Sources of additional information
- References
- Chapter 15: Early nutrition and its effect on the development of functional gastrointestinal disorders
- Abstract
- 15.1: Introduction
- 15.2: FGIDS and consequences
- 15.3: Infants (0–12 months)
- 15.4: Hydrolysates can soften the stools
- 15.5: Between 1 and 4 years
- 15.6: Conclusions
- 15.7: Future trends and research
- Sources of additional information
- References
- Part III: Promoting long-term health: Taking action in the first 1000 days
- Chapter 16: Prenatal nutrition and nutrition in pregnancy: Effects on long-term growth and development
- Abstract
- 16.1: Background
- 16.2: Epidemiology
- 16.3: Evidence from animal studies
- 16.4: Evidence from human studies
- 16.5: Evidence from nutrition interventions studies among human
- 16.6: Future trends and research
- 16.7: Conclusion
- Sources of additional information
- References
- Chapter 17: Addressing nutritional needs in preterm infants to promote long-term health
- Abstract
- 17.1: Introduction
- 17.2: Prematurity and long-term consequences
- 17.3: Feeding the preterm infant: Nutritional needs and feeding practices
- 17.4: Conclusions
- 17.5: Future trends and research
- Sources of additional information
- References
- Chapter 18: Early nutrition, the development of obesity, and its long term consequences
- Abstract
- 18.1: Introduction
- 18.2: Addressing the problem
- 18.3: Modifiable factors in preconception and pregnancy
- 18.4: Modifiable factors in early infancy associated with obesity
- 18.5: Summary: Modifiable factors for obesity prevention in early life
- 18.6: Intervention
- 18.7: Future directions
- 18.8: Conclusion
- Sources of additional information
- References
- Chapter 19: Establishing healthy eating patterns in infancy
- Abstract
- 19.1: Introduction
- 19.2: Learning how to eat: Developmental stages and factors in infants’ and toddlers’ eating skill and behaviors
- 19.3: Child-caring in child eating behavior formation, nutrition, and growth: The role of food parenting practices and styles
- 19.4: Future trends and research
- 19.5: Conclusion
- Sources of further information
- References
- Chapter 20: Early parent feeding behaviors to promote long-term health
- Abstract
- 20.1: Introduction
- 20.2: Responsive parenting and feeding behaviors
- 20.3: Parenting feeding practices and behaviors
- 20.4: Existing guidance for how to feed
- 20.5: Measures of parent feeding behaviors
- 20.6: Hunger and satiety cues
- 20.7: Parent assessment of hunger and satiety cues
- 20.8: Using food to soothe during infancy
- 20.9: Breastfeeding, expressed human milk, and responsive feeding
- 20.10: Consideration when offering milk in a bottle
- 20.11: Parent feeding practices and introduction of complementary foods
- 20.12: Parent feeding practices and child weight outcomes
- 20.13: Conclusions
- 20.14: Future research needs
- Sources of additional information
- References
- Chapter 21: Programming long-term health: Nutrition and diet in infants aged 6 months to 1 year
- Abstract
- 21.1: Introduction
- 21.2: Basic nutritional needs
- 21.3: Major foods in the CF period
- 21.4: Poor nutrition
- 21.5: Selected food-related health outcomes
- 21.6: Future trends and research
- 21.7: Summary and conclusions
- Sources of additional information
- References
- Chapter 22: Developing science-based dietary guidelines for infants and toddlers
- Abstract
- Acknowledgments
- 22.1: Introduction
- 22.2: Considerations for developing quantitative food based dietary guidelines for infants and toddlers
- 22.3: Milk feeding and energy requirements
- 22.4: Nutrient requirements during complementary feeding
- 22.5: Dietary patterns
- 22.6: Methodologies for developing dietary guidelines
- 22.7: A review of current quantitative food-based dietary guidelines from developed countries
- 22.8: Conclusions and public health implications
- 22.9: Future trends
- Sources of additional information
- References
- Index
- Edition: 2
- Published: August 6, 2022
- Imprint: Woodhead Publishing
- No. of pages: 650
- Language: English
- Paperback ISBN: 9780128243893
- eBook ISBN: 9780128244050
JS
Jose M Saavedra
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