Durability and Reliability of Medical Polymers
- 1st Edition - August 13, 2012
- Latest edition
- Editors: Mike Jenkins, Artemis Stamboulis
- Language: English
Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of… Read more
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Description
Description
Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.
With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians.
Key features
Key features
- Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers
- Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers
- Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body
Readership
Readership
Table of contents
Table of contents
Contributor contact details
Woodhead Publishing Series in Biomaterials
Part I: Types and properties of bioresorbable medicalpolymers
Chapter 1: Types of bioresorbable polymers for medical applications
Abstract:
1.1 Introduction
1.2 Aliphatic polyesters
1.3 Polyanhydrides
1.4 Poly(ortho esters)
1.5 Polyphosphazenes
1.6 Poly(amino acids) and ‘pseudo’ poly(amino acids)
1.7 Polyalkylcyanoacrylates
1.8 Poly(propylene fumarate) (PPF), poloxamers, poly(p-dioxanone) (PPDO), polyvinyl alcohol (PVA)
Chapter 2: The effect of molecular structure on the properties of biomedical polymers
Abstract:
2.1 Introduction: the molecular structure of polymers
2.2 Molecular weight and polymer properties
2.3 Macromolecular conformation, crystallisation and polymer properties
2.4 The effect of the amorphous state and glass transition temperature on polymer properties
2.5 Biphasic systems: linear crystalline polymers and their properties
Chapter 3: Processing of bioresorbable and other polymers for medical applications
Abstract:
3.1 Introduction
3.2 Extrusion
3.3 Mixing processes
3.4 Molding processes
3.5 Secondary shaping
3.6 Calendering
3.7 Coating
3.8 Foaming
3.9 Solvent casting
3.10 Challenges in biopolymer processing
3.11 Conclusions
Chapter 4: Understanding transport phenomena and degradation of bioresorbable medical polymers
Abstract:
4.1 Introduction to transport phenomena in irreversible processes
4.2 Introduction to mathematical modelling
4.3 Conclusions and future trends
Chapter 5: Synthetic bioresorbable polymers
Abstract:
5.1 Introduction
5.2 Bioresorbable polymers
5.3 Degradation of aliphatic polyesters
5.4 Factors affecting aliphatic polymer degradation
5.5 Processing and devices
5.6 Conclusions
Chapter 6: Using synthetic bioresorbable polymers for orthopedic tissue regeneration
Abstract:
6.1 Introduction
6.2 Poly (α-hydroxy acids)
6.3 Polylactones
6.4 Polyanhydrides
6.5 Fumarate-based polymers
6.6 Hydrogels
6.7 Future trends
6.8 Conclusions
Part II: Aspects of durability and reliability of non-bioresorbable medical polymers
Chapter 7: Wear processes in polymer implants
Abstract:
7.1 Introduction
7.2 Implants
7.3 Wear processes and theory for polymer implants
7.4 Polymers
7.5 Wear debris in the body
7.6 Future trends
7.7 Sources of further information and advice
Chapter 8: Ageing processes of biomedical polymers in the body
Abstract:
8.1 Introduction
8.2 Principles of chemical and biochemical degradation and calcification
8.3 Effect of natural ageing of medical polymers
8.4 Principles of accelerated ageing
8.5 Conclusions and summary
8.6 Sources of further information and advice
8.7 Acknowledgements
Chapter 9: The failure of synthetic polymeric medical devices
Abstract:
9.1 Introduction
9.2 Forensic methods
9.3 Catheter failure
9.4 Balloon catheters and angioplasty
9.5 Breast implants
9.6 Intraocular lenses
9.7 Failure of Foley catheters
9.8 Sutures
9.9 Conclusions
9.10 Acknowledgements
Chapter 10: Manufacturing defects in polymeric medical devices
Abstract:
10.1 Introduction
10.2 Polymer moulding
10.3 Catheter systems
10.4 Security cap for gas cylinders
10.5 Breathing tube failures
10.6 A failed crutch
10.7 Cracked medical tubing
10.8 Conclusions
10.9 Acknowledgements
Index
Product details
Product details
- Edition: 1
- Latest edition
- Published: August 13, 2012
- Language: English
About the editors
About the editors
MJ
Mike Jenkins
AS
Artemis Stamboulis
Dr. Artemis Stamboulis is a Professor of Biomaterials, at the School of Metallurgy and Materials, the University of Birmingham, UK. She obtained her PhD, from the National Technical University of Athens and TU Berlin, Germany in Polymer Engineering. Following her PhD, she was awarded a prestigious Marie Sklodowska Curie Fellowship to work on natural fibre polymer composites in the Department of Materials, Imperial College London followed by two more fellowships at the same University acquiring additional knowledge and expertise in bioactive glasses, biomedical glasses and glass ionomer cements. This opened opportunities for Dr Stamboulis to grow in the field of Biomaterials and continue developing biomedical glasses and glass ceramics as well as working with hydroxyapatite and antimicrobial hydroxyapatite. A prestigious Birmingham Fellowship allowed Dr Stamboulis to start her research group at the University of Birmingham where she is now Professor of Biomaterials currently developing antimicrobial biomaterials based on antimicrobial peptides and nanocoatings for polymer, ceramic and metallic implants.