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Dopaminergic Ergot Derivatives and Motor Function

Proceedings of an International Symposium Held in the Wenner-Gren Center, Stockholm, July 24-25, 1978

1st Edition - January 1, 1979

Editors: Kjell Fuxe, Donald B. Calne

Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 1 - 6 0 9 7 - 9

Dopaminergic Ergot Derivatives and Motor Function is a collection of papers from the proceedings of an international symposium of the same topic, held in Stockholm on July 24-25,… Read more

Dopaminergic Ergot Derivatives and Motor Function

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Dopaminergic Ergot Derivatives and Motor Function is a collection of papers from the proceedings of an international symposium of the same topic, held in Stockholm on July 24-25, 1978. This collection of papers covers laboratory studies on different subjects such as the anatomy, physiology, biochemistry, and pharmacology of dopaminergic pathways of the brain. This book also discusses clinical research dealing on dopaminergic receptors observed in Parkinsonism and in Huntington's disease. One paper reviews the neural circuitry of the basal ganglia as it is the part of the brain that is first and foremost involved in skeletomuscular mechanisms. Another paper deals with the different groups of ergot derivatives and their structure-activity relationships. The book also addresses the therapeutic activity and toxicity made during these observations. The text then discusses the psychiatric reaction to ergot derivatives, including LSD-induced hallucinations. Another paper examines the effects of dopaminergic ergots on the anterior pituitary function that is limited to the control of prolactin secretion during chronic therapy. This book is valuable to microbiologists, microchemists, and laboratory researchers and scientists dealing with neuro-functions and the brain.