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Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer
1st Edition - February 1, 2024
Editors: Ashok Kumar, Neha Arya, Shikha Tiwari, Raju Khan
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 9 6 8 - 8
Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and… Read more
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Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.
- Covers the role of the tumor microenvironment in head and neck cancer
- Provides information on oncogenic and tumor suppressor miRNAs dysregulated in HNSCC patients
- Elucidates the role of miRNAs in metastasis, recurrence, and chemoresistance in HNSCC
- Includes the current state-of-art in miRNA-based clinical trials for head
Clinicians, biochemists, molecular biologists, pathologists, medical oncologists, radiation oncologists, pharmacologists, medical practitioners, bioengineers, academic institutes, etc. Pharmaceutical companies for the development of novel diagnostic and therapeutic technologies for the management of HNSCC
1. Epidemiology, pathology and genomic topography of head and neck cancer
2. Association of human papillomavirus with head and neck cancer
3. microRNA regulation of different subtypes of head and neck cancer
4. Oncogenic and tumor suppressor microRNAs in head and neck cancer
5. Epigenetic regulation of head and neck cancer by microRNAs
6. Association of genetic variations in microRNAs with susceptibility to head and neck cancer
7. Role of microRNAs in metastasis, recurrence and chemo-radiation resistance of head and neck cancer
8. Regulation of head and neck tumor microenvironment by microRNAs
9. Genome wide discovery and prediction of microRNA-based biomarkers in head and neck squamous cell carcinoma
10. Computational modelling for identification of miRNAs as diagnostic and prognostic biomarkers for head and neck cancer
11. Development of microRNA as diagnostic markers in head and neck cancer
12. Development of microRNA as prognostic markers in head and neck cancer
13. Exosomal microRNA for diagnosis and prognosis of head and neck cance
14. MicroRNA expression profiling for disease progression assessment
15. MicroRNA-based point-of-care devices for diagnosis and prognosis of head and neck cancer
16. Therapeutic role of microRNAs in management of head and neck cancer
17. miRNAs in the management of nutritional deficiencies and cachexia in Head and Neck Cancer patients
18. MicroRNA-based nanomedicine for treatment of head and neck cancer
19. MicroRNA-based clinical trials for head and neck cancer
2. Association of human papillomavirus with head and neck cancer
3. microRNA regulation of different subtypes of head and neck cancer
4. Oncogenic and tumor suppressor microRNAs in head and neck cancer
5. Epigenetic regulation of head and neck cancer by microRNAs
6. Association of genetic variations in microRNAs with susceptibility to head and neck cancer
7. Role of microRNAs in metastasis, recurrence and chemo-radiation resistance of head and neck cancer
8. Regulation of head and neck tumor microenvironment by microRNAs
9. Genome wide discovery and prediction of microRNA-based biomarkers in head and neck squamous cell carcinoma
10. Computational modelling for identification of miRNAs as diagnostic and prognostic biomarkers for head and neck cancer
11. Development of microRNA as diagnostic markers in head and neck cancer
12. Development of microRNA as prognostic markers in head and neck cancer
13. Exosomal microRNA for diagnosis and prognosis of head and neck cance
14. MicroRNA expression profiling for disease progression assessment
15. MicroRNA-based point-of-care devices for diagnosis and prognosis of head and neck cancer
16. Therapeutic role of microRNAs in management of head and neck cancer
17. miRNAs in the management of nutritional deficiencies and cachexia in Head and Neck Cancer patients
18. MicroRNA-based nanomedicine for treatment of head and neck cancer
19. MicroRNA-based clinical trials for head and neck cancer
- No. of pages: 270
- Language: English
- Published: February 1, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443159688
AK
Ashok Kumar
Dr. Ashok Kumar is currently working as an Associate Professor in the Department of Biochemistry of All India Institute of Medical Sciences Bhopal. His current research interest is understanding the role of non-coding RNAs and sphingosine-1-phosphate signaling in Head and Neck Cancer. He received his PhD degree from Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS) Lucknow, India. Then, he received postdoctoral training from UCSFBenioff’s Children’s Hospital Oakland & Research Centre, Oakland, CA, USA. Dr. Ashok Kumar’s major area of research work are Cell & Molecular Biology, Cancer Biology, Immunology & Sphingolipid signaling. He has more than 15 years of research experience. He has published more than 50 research articles and 10 book chapters and he has edited two books. He is a member of several international professional societies including American Association of Cancer Research and Fellow of Royal Society of Biology
Affiliations and expertise
Associate Professor, Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Bhopal, MP, IndiaNA
Neha Arya
Dr. Neha Arya is currently working as an Assistant Professor at the Translational Medicine Centre, AIIMS Bhopal. Her major interests include design and fabrication of biomaterials for tissue engineering and drug delivery applications with a special focus on in vitro disease models and nanotechnology in cancer therapeutics. She received her Bachelor’s degree from Gargi College, University of Delhi, India and her Master’s degree from South Campus, University of Delhi. She earned her Ph.D degree from Department of Biological Sciences and Bioengineering, Indian Institute of Technology (IIT), Kanpur following which she went to University of Freiburg, Germany as a Post Doctoral Researcher. She then worked as a DST INSPIRE Faculty Fellow at the Department of Biochemistry, AIIMS, Bhopal, India followed by working at the Department of Medical Devices, NIPER Ahmedabad as an Assistant Professor. She has several International publications, book chapters and served as a co-inventor in 2 patents. She has also received several awards and research grants from the Government of India for her research
Affiliations and expertise
Assistant Professor at the Translational Medicine Centre, AIIMS Bhopal.ST
Shikha Tiwari
Dr. Shikha Tiwari is currently working as Women Scientist in the Department of Biochemistry, All India Institute of Medical Sciences Bhopal. Her current research interest is understanding the role of single nucleotide polymorphism in miRNAs to genetic susceptibility towards oral squamous cell carcinomas. She received his PhD degree from Maulana Azad National Institute of Technology, Bhopal, India. Thereafter, she worked as an Assistant Professor in MGMM Jabalpur, India. Dr. Shikha Tiwari’s major area of research work is Cancer diagnosis, Bioinformatics and molecular biology. She has published 11 research articles in referred journals
Affiliations and expertise
DHR-Women Scientist, Department of Biochemistry, All India Institute of Medical Sciences Bhopal, IndiaRK
Raju Khan
Raju Khan, FRSC, is a Senior Principal Scientist & Professor, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Bhopal, MP, India. He has more than 15 years of experience in electrochemistry to explore electrochemical properties of nanostructure materials to design and develop efficient biosensor devices integrated with microfluidics for biomedical applications.
Affiliations and expertise
Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced, Materials and Processes, Research Institute (AMPRI), Bhopal, Madhya, Pradesh, India