
Diagnostic Pathology: Placenta
- 3rd Edition - June 10, 2024
- Authors: Amy Heerema-McKenney, Edwina J. Popek, Monique E. De Paepe
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 6 5 4 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 0 1 - 5
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects… Read more

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Request a sales quoteThis expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of placental pathology and the critical role the placenta plays in the unique interface between mother and fetus, this volume incorporates the most up-to-date scientific and technical knowledge to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Placenta is a visually stunning, one-stop resource for every practicing pathologist, fellow, resident, or student as an ideal day-to-day reference or as a reliable training resource, and is useful to even the most experienced placental pathologist for diagnostic criteria, grading, and relevance of placental tissue samples.
- Covers all areas of placental pathology, with clear and concise information on gross and microscopic changes of the placenta, common diagnoses, and placental evaluation in special circumstances
- Provides expert guidance on key topics, such as maternal mortality, gestational trophoblastic disease, placental pathology constellations, and typical clinical correlates; pregnancy complications, such as preeclampsia, intrauterine growth restriction, and multiple gestation; and the pathology of disorders of placental implantation and the postpartum hysterectomy
- Features detailed, up-to-date information on maternal COVID-19 and placental pathology, including SARS-CoV-2 placentitis, and new chapters on fetal hydrops, common placental associations with stillbirth, second-trimester demise, and more
- Contains significantly updated information throughout, including new content, images, and references to reflect the most current diagnoses and provide ease for daily case sign-out
- Features more than 1,850 print and online images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, radiology images, and online video content (including quick tutorials on key pathologic diagnoses) to help practicing and in-training pathologists reach a confident diagnosis
- Employs consistently templated chapters, bulleted content, key facts, annotated images, reference tables for placental evaluation, sample templates for gross and microscopic placental description, and an extensive index for quick, expert reference at the point of care
- Includes an eBook version that provides you access to all text, figures, and references with the ability to search and customize your content, have it read aloud, and make notes and highlights
Placental pathologists and gynecologic pathologists at all levels of training
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedications
- Contributing Authors
- Preface
- Acknowledgments
- Sections
- List of Tables
- SECTION 1: OVERVIEW OF GROSS AND MICROSCOPIC CHANGES
- UMBILICAL CORD
- Chapter 1: Gross Evaluation and Normal Histology of Umbilical Cord
- Main Text
- Tables
- Image Gallery
- Chapter 2: Umbilical Cord Coiling
- Main Text
- Image Gallery
- Chapter 3: Knots
- Main Text
- Image Gallery
- Chapter 4: Umbilical Cord Edema and Thinning
- Main Text
- Image Gallery
- Chapter 5: Histopathologic Changes of Umbilical Cord
- Main Text
- Tables
- Image Gallery
- EXTRAPLACENTAL MEMBRANES
- Chapter 6: Gross Evaluation and Normal Histology of Membranes
- Main Text
- Image Gallery
- Chapter 7: Histopathologic Changes of Membranes
- Main Text
- Tables
- Image Gallery
- CHORIONIC PLATE
- Chapter 8: Gross Evaluation and Normal Histology of Chorionic Plate
- Main Text
- Image Gallery
- Chapter 9: Histopathologic Changes of Chorionic Plate
- Main Text
- Image Gallery
- STEM VILLI
- Chapter 10: Gross Evaluation and Normal Histology of Stem Villi
- Main Text
- Image Gallery
- Chapter 11: Histopathologic Changes of Stem Villi
- Main Text
- Image Gallery
- CHORIONIC VILLI
- Chapter 12: Gross Evaluation and Normal Histology of Chorionic Villi
- Main Text
- Image Gallery
- Chapter 13: Histopathologic Changes of Chorionic Villi
- Main Text
- Image Gallery
- SEPTA, INTERVILLOUS SPACE, AND BASAL PLATE
- Chapter 14: Gross Evaluation and Normal Histology of Septa, Intervillous Space, and Basal Plate
- Main Text
- Image Gallery
- Chapter 15: Histopathologic Changes of Septa, Intervillous Space, and Basal Plate
- Main Text
- Image Gallery
- DECIDUA
- Chapter 16: Gross Evaluation and Normal Histology of Decidua
- Main Text
- Tables
- Image Gallery
- Chapter 17: Histopathologic Changes of Decidua
- Main Text
- Image Gallery
- FALLOPIAN TUBE
- Chapter 18: Fallopian Tube After Opportunistic Salpingectomy
- Main Text
- Image Gallery
- SECTION 2: PLACENTAL DIAGNOSES
- MECONIUM
- Chapter 19: Meconium-Stained Placenta
- Main Text
- Tables
- Image Gallery
- INTRAUTERINE INFLAMMATION/INFECTION
- Chapter 20: Maternal and Fetal Inflammatory Response
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Chapter 21: Group B Streptococcus
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 22: Escherichia coli and Other Enterobacteriaceae
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 23: Listeria monocytogenes
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 24: Fusobacterium Species and Other Anaerobic Bacteria
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 25: Other Bacterial and Mycobacterial Species
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 26: Candida
- Key Facts
- Key Images
- Main Text
- Image Gallery
- PLACENTAL INFECTIONS WITH VILLITIS AND OTHER FINDINGS
- Chapter 27: Parvovirus B19
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 28: Cytomegalovirus
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 29: Herpes Simplex Virus
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 30: Other Herpesviruses
- Main Text
- Image Gallery
- Chapter 31: SARS-CoV-2 (COVID-19)
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 32: Other Viruses
- Main Text
- Image Gallery
- Chapter 33: Syphilis
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 34: Coccidioidomycosis
- Key Facts
- Key Images
- Main Text
- Chapter 35: Parasites
- Main Text
- Image Gallery
- CHRONIC INFLAMMATORY LESIONS
- Chapter 36: Cellular Composition of Chronic Inflammatory Lesions
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 37: Chronic Villitis
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 38: Chronic Histiocytic Intervillositis
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Chapter 39: Basal Chronic Villitis and Chronic Deciduitis
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 40: Chronic Chorioamnionitis and Chorionic Histiocytic Hyperplasia
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 41: Eosinophilic/T-Cell Chorionic Vasculitis
- Key Facts
- Key Images
- Main Text
- Image Gallery
- MASSIVE PERIVILLOUS FIBRIN DEPOSITION AND MATERNAL FLOOR INFARCTION
- Chapter 42: Massive Perivillous Fibrin Deposition and Maternal Floor Infarction
- Key Facts
- Key Images
- Main Text
- Image Gallery
- FETAL VASCULAR MALPERFUSION
- Chapter 43: Large Vessel Fetal Vascular Malperfusion
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 44: Distal Villous Lesions of Fetal Vascular Malperfusion
- Key Facts
- Key Images
- Main Text
- Image Gallery
- MATERNAL VASCULAR MALPERFUSION
- Chapter 45: Small-for-Gestational-Age Placenta
- Main Text
- Image Gallery
- Chapter 46: Accelerated Villous Maturation
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Video Gallery
- Chapter 47: Distal Villous Hypoplasia
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Video Gallery
- Chapter 48: Decidual Arteriopathy
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Video Gallery
- Chapter 49: Infarcts
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Video Gallery
- Chapter 50: Acute Abruption and Retroplacental Hematoma
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 51: Chronic Abruption
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Video Gallery
- VILLOUS HYPERVASCULAR LESIONS
- Chapter 52: Chorangiosis
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 53: Chorangiomatosis
- Key Facts
- Key Images
- Main Text
- Chapter 54: Chorangioma
- Key Facts
- Key Images
- Main Text
- Image Gallery
- GESTATIONAL TROPHOBLASTIC DISEASE, RELATED LESIONS, AND OTHER TUMORS
- Chapter 55: Hydropic Degeneration
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Chapter 56: Partial Hydatidiform Mole
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Video Gallery
- Chapter 57: Complete Hydatidiform Mole
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Chapter 58: Gestational Choriocarcinoma
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 59: Placental Site Nodule and Atypical Placental Site Nodule
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 60: Exaggerated Placental Site
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 61: Placental Site Trophoblastic Tumor
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 62: Epithelioid Trophoblastic Tumor
- Key Facts
- Key Images
- Main Text
- Tables
- Image Gallery
- Chapter 63: Metastatic Tumors
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 64: Uterine Tumors Associated With Placenta
- Main Text
- Image Gallery
- PLACENTAL MESENCHYMAL DYSPLASIA
- Chapter 65: Placental Mesenchymal Dysplasia
- Key Facts
- Key Images
- Main Text
- Image Gallery
- SECTION 3: PLACENTAL EVALUATION IN SPECIAL CIRCUMSTANCES
- DIABETES IN PREGNANCY AND MATERNAL OBESITY
- Chapter 66: Diabetes and Obesity in Pregnancy
- Main Text
- Image Gallery
- Chapter 67: Placentomegaly
- Main Text
- Image Gallery
- Chapter 68: Delayed Villous Maturation
- Key Facts
- Key Images
- Main Text
- Image Gallery
- PREECLAMPSIA AND MATERNAL VASCULAR MALPERFUSION
- Chapter 69: Preeclampsia and Related Hypertensive Disorders
- Main Text
- Image Gallery
- FETAL-MATERNAL HEMORRHAGE
- Chapter 70: Fetal-Maternal Hemorrhage
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 71: Thrombohematoma and Intervillous Thrombus
- Key Facts
- Key Images
- Main Text
- Image Gallery
- FETAL HYDROPS
- Chapter 72: Hemolytic Disease of Fetus and Newborn
- Main Text
- Image Gallery
- Chapter 73: Non-Immune-Mediated Hydrops
- Main Text
- Image Gallery
- FETAL GROWTH RESTRICTION
- Chapter 74: Placental Causes of Poor Fetal Growth
- Main Text
- Image Gallery
- PREMATURITY
- Chapter 75: Placental Findings in Premature Birth
- Main Text
- Image Gallery
- ABNORMAL PLACENTAL IMPLANTATION
- Chapter 76: Placenta Accreta Spectrum
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 77: Ectopic Pregnancy
- Key Facts
- Key Images
- Main Text
- Image Gallery
- INTRAUTERINE FETAL DEMISE
- Chapter 78: 1st-Trimester Pregnancy Loss
- Main Text
- Tables
- Image Gallery
- Chapter 79: 2nd-Trimester Fetal Demise
- Main Text
- Tables
- Image Gallery
- Chapter 80: 3rd-Trimester Fetal Demise
- Main Text
- Tables
- Image Gallery
- Chapter 81: Recurrent Pregnancy Loss
- Main Text
- Image Gallery
- Chapter 82: In Utero Demise-to-Delivery Interval Changes
- Main Text
- Tables
- Image Gallery
- Chapter 83: Hypoxic-Ischemic Encephalopathy
- Key Facts
- Key Images
- Main Text
- Image Gallery
- MULTIPLE GESTATIONS
- Chapter 84: Complications of Monochorionic-Monoamniotic Twin Gestations
- Main Text
- Image Gallery
- Chapter 85: Twin Growth Discrepancy
- Main Text
- Tables
- Image Gallery
- Chapter 86: Twin-Twin Transfusion Syndrome
- Main Text
- Image Gallery
- Chapter 87: Twin Anemia-Polycythemia Sequence
- Main Text
- Image Gallery
- Chapter 88: After In Utero Intervention for Twin-Twin Transfusion Syndrome
- Main Text
- Image Gallery
- Chapter 89: Triplet and Higher Order Placenta
- Main Text
- Image Gallery
- MATERNAL COMPLICATIONS OF PREGNANCY
- Chapter 90: Maternal Mortality
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 91: Postpartum Hemorrhage
- Key Facts
- Key Images
- Main Text
- Image Gallery
- Chapter 92: Evaluation of Postpartum Hysterectomy
- Main Text
- Image Gallery
- SECTION 4: APPENDIX
- REFERENCE CHARTS FOR PLACENTAL EVALUATION
- Chapter 93: Weights for Singleton Placentas
- Main Text
- Tables
- Chapter 94: Weights for Twin Placentas
- Main Text
- Chapter 95: Weights for Triplet Placentas
- Main Text
- Chapter 96: Reference Values for Fetal and Placental Growth in Early Pregnancy
- Main Text
- SAMPLE TEMPLATES FOR PLACENTAL EVALUATION
- Chapter 97: Singleton Placenta Gross Evaluation
- Main Text
- Chapter 98: Twin Placenta Gross Evaluation
- Main Text
- Chapter 99: Placenta Microscopic Evaluation
- Main Text
- Chapter 100: Placenta Triage
- Main Text
- Tables
- INDEX
- No. of pages: 552
- Language: English
- Edition: 3
- Published: June 10, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780443116544
- eBook ISBN: 9780443117015
AH
Amy Heerema-McKenney
Amy Heerema-McKenney, MD is Director of Perinatal Pathology at the Robert J. Tomsich Pathology and Laboratory Medicine Institute, Division of Anatomic Pathology for Cleveland Clinic in Cleveland, Ohio
Affiliations and expertise
Director of Perinatal Pathology, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Division of Anatomic Pathology, Cleveland Clinic, Cleveland, OhioEP
Edwina J. Popek
Edwina J. Popek, DO, is
Professor Emeritus of Pathology, Immunology and Pediatrics, Baylor College of Medicine, Texas Children's Hospital Pavilion for Women in Houston, TexasAffiliations and expertise
Professor Emeritus of Pathology, Immunology and Pediatrics, Baylor College of Medicine, Texas Children's Hospital Pavilion for Women in Houston, TexasMD
Monique E. De Paepe
Monique De Paepe, MD, MSc is Professor of Pathology and Laboratory Medicine at Women and Infants Hospital, Alpert Medical School of Brown University in Providence, Rhode Island
Affiliations and expertise
Professor of Pathology and Laboratory Medicine, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island