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Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodeve… Read more
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Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. In addition, the book also examines the pharmacological and non-pharmacological interventions of development-related conditions.
Neuroscientists, geriatricians, neurobiologists, experimental biologists, clinicians, graduate students, and post-doctoral fellows
I. Introductory chapters: Setting the scene for the neuroscience of development
1. The structure of the human brain as revealed in six histological sections
Richard Armstrong
2. Neural tube defects: embryonic origin, cell survival equilibrium impact, and clinical features
Chiara Parodi, Paolo Grazioli, Laura Avagliano, Timothy M. George, Gaetano P. Bulfamante, Richard H. Finnell and Valentina Massa
3. Chemical substances affecting neurodevelopment
Munekazu Komada
4. High-risk babies and neurodevelopmental outcome
Merina Shrestha
5. Genomic imprinting and neurodevelopment
Ines Lopez del Castillo, Anna Lozano-Ureña and Sacri R. Ferron
6. Insights from model systems: alcohol, neurodevelopment and zebrafish
Robert Gerlai
7. Maternal iodine nutrition and neurodevelopment in the offspring
Shao Jia Zhou
8. Endocrine aspects of development. Thyroid hormone actions in neurological processes during brain development
Ana Montero-Pedrazuela, Carmen Grijota-Martınez, Eva Auso, Soledad Barez-Lopez and Ana Guadaño-Ferraz
II. Impairments and Diseases
9. Pediatric brain tumors
Sherif G. Shaaban and Stephanie A. Terezakis
10. Neurofibromatosis type 1: from cellular phenotypes to human brain function
Ines Bernardino, Joana Goncxalves and Miguel Castelo-Branco
11. Current insights into neural crest cell development and pathologies
Rebekah M. Charney, Maneeshi S. Prasad and Martın I. Garcıa-Castro
12. Spina Bifida: a biopsychosocial perspective
Diana M. Ohanian, Adrien M. Winning, Laura M. Nicholson and Grayson N. Holmbeck
13. Diabetic ketoacidosis and neurodevelopment
Walter Zegarra and Tandy Aye
14. Four-dimensional features of fetal brain: applications to diabetes
Panagiotis Antsaklis, George Daskalakis and Asim Kurjak
15. Developmental effects of nicotine on cognitive, motivated, and executive behaviors
Kristi A. Kohlmeier and Filip S. Polli
16. Maternal methamphetamine and impact on the developing brain
Romana Slamberova and Kateryna Nohejlova
17. Alcohol, cannabis and brain development
Kristen Rian Breit
18. The environmental pollutant trichloroethylene disrupts key neural pathways during brain development
Briana R. De Miranda and Sarah J. Blossom
19. Developmental neurotoxicity of the herbicide atrazine
Janiel Ahkin Chin Tai and Jennifer L. Freeman
20. Neurodevelopmental delays and in utero exposure to hyperemesis gravidarum
Marlena S. Fejzo and Patrick M. Mullin
21. Neurodevelopment and PCDH19-related developmental and epileptic encephalopathy (PCDH19-DDE)
Silvia Bassani, Carla Marini and Maria Passafaro
22. Neurodevelopment in turner syndrome
Reid Blanchett and Rebecca C. Knickmeyer
23. Very preterm children and the impact on neurodevelopmental outcomes
Leona Pascoe and Peter J. Anderson
24. Linking congenital heart disease and brain functional connectivity in newborns
Josepheen De Asis-Cruz and Catherine Limperopoulos
25. Brain growth in congenital heart disease from prenatal environment to adulthood
Cynthia Ortinau
26. Adolescent dopamine development: connecting experience with vulnerability or resilience to psychiatric disease
Lauren M. Reynolds and Cecilia Flores
27. Developmental coordination disorder
Jill Glennis Zwicker
III. Biomarkers, screening, methods and diagnosis
28. Neurodevelopment and the Ages and Stages Questionnaire, third edition (ASQ-3)
N. Granana and A.M. Romero Otalvaro
29. Attention deficit hyperactivity disorder screening in childhood and adolescence
Steven James Korzeniewski
30. The Mini-Mental State Pediatric Examination: a cognitive screening test for Italian children
Valeria Peviani, Pina Scarpa and Gabriella Bottini
31. Predictors of neurodevelopment in preterm infants: from the neonatal intensive care unit into adulthood
Pilar Medina-Alva
32. Antenatal fetal neurodevelopment test: KANET assessment
Toshiyuki Hata and Mohamed Ahmed AboEllail
IV: Management and treatments
33. Pain evaluation and management in neurodevelopmental conditions
Marlon L. Wong and Eva Widerstrom-Noga
34. Use of levetiracetam in neonates: features and applications (a narrative review)
Shannon Pollock and Louis N. Manganas
35. Quetiapine treatment in paediatric scenarios
Barbara Plemeniti Tololeski and Maja Drobnic Radobuljac
36. Treatments with cannabinoids and brain development
P. Schonhofen, D.M. Vargas, R.B. Parsons and Fabio Klamt
37. Deep brain stimulation for pediatric dystonia: neurophysiological, behavioral, and functional changes and their clinical relevance
Lior M. Elkaim and George M. Ibrahim
38. Use of repetitive transcranial magnetic stimulation in neurodevelopment: A narrative review
Yoshihiro Noda
39. Cognitive behavioral therapy in children with anxiety disorders
Gabrielle Gloston, Michael A. Sustaita, Ana C. Ramirez, Saira A. Weinzimmer, Andres G. Viana, Eric A. Storch and Sophie C. Schneider
40. Cognitive behavioral therapy for anxiety in children with autism spectrum disorder
Ana C. Ramirez, Mayra I. Perez, Danica Limon, Eric A. Storch and Sophie C. Schneider
41. Nutritional treatment in fetal alcohol spectrum disorder (FASD)
Oscar Garcıa-Algar, Giorgia Sebastiani, Vicente Andreu- Ferna
42. Nurturing the developing brain to reduce neurological delay
Kelly A. Vaughn, Bartlett D. Moore, IV and Dana DeMaster
43. Normalizing perinatal neurological development via intervention
Dana DeMaster, Kelly A. Vaughn and Bartlett D. Moore, IV
V. Models and modelling
44. Microplatforms as a model for neurological conditions
George Deeb, Zeina Bou Diab, Jessica Saliba, Arij Daou and Rami Mhanna
45. Disease models in neurodevelopmental disorders
Pietro Fazzari, Angela Rodriguez-Prieto and Maximo Ibo Galindo
46. Developmental neurotoxicity of endosulfan: modeling with zebrafish
Karina Dale, Josef Daniel Rasinger and Ståle Ellingsen
47. Neurodevelopment of the zebrafish spinal serotonin system
Mark A. Masino and Jacob E. Montgomery
48. Inbred mouse model of brain development and intestinal microbiota
Reinaldo B. Oria, Daniel V. Pinto, Ronaldo P. Dias, Ramon S. Raposo, Patricia L. Foley, Joaeo O. Malva and Richard L. Guerrant
49. The myelin mutant taiep rat as a model for developmental brain disorders
Jose R. Eguibar, Carmen Cortes, Juan C. Ahumada-Juarez, Valeria Piazza and Victor Hugo Hernandez Gonzalez
50. The MAM-E17 neurodevelopmental model of schizophrenia
Marzena Mackowiak
VI. Resources
51. Recommended resources on the neuroscience of development
Rajkumar Rajendram and Victor R. Preedy
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VP
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Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.