Determination of Organic Structures by Physical Methods
- 1st Edition - January 1, 1955
- Latest edition
- Editors: E. A. Braude, F. C. Nachod
- Language: English
Determination of Organic Structures by Physical Methods, Volume 1 focuses on the processes, methodologies, principles, and approaches involved in the determination of organic… Read more
Determination of Organic Structures by Physical Methods, Volume 1 focuses on the processes, methodologies, principles, and approaches involved in the determination of organic structures by physical methods, including infrared light absorption, thermodynamic properties, Raman spectra, and kinetics. The selection first elaborates on the phase properties of small molecules, equilibrium and dynamic properties of large molecules, and optical rotation. Discussions focus on simple acyclic compounds, carbohydrates, steroids, diffusion, viscosity, osmotic pressure, sedimentation velocity, melting and boiling points, and molar volume. The book then examines ultraviolet and visible light absorption, infrared light absorption, Raman spectra, and the theory of magnetic susceptibility. Concerns cover applications to the study of organic compounds, applications to the determination of structure, determination of thermodynamic properties, and experimental methods and evaluation of data. The text ponders on wave-mechanical theory, reaction kinetics, and dissociation constants, including dissociation of molecular addition compounds, principles of reaction kinetics, and valence-bond treatment of aromatic systems. The selection is a valuable source of data for researchers interested in the determination of organic structures by physical methods.
Preface
List of Contributors
Part I. The Determination of Molecular Size
1. Phase Properties of Small Molecules
1.1. Introduction
1.2. Melting Points
1.3. Boiling Points
1.4. Molar Volume
1.5. Parachor
References
2. Equilibrium and Dynamic Properties of Large Molecules
2.1. Introduction
2.2. Osmotic Pressure
2.3. Sedimentation Equilibrium
2.4. Sedimentation Velocity
2.5. Diffusion
2.6. Viscosity
2.7. Comparison of Results Obtained by Different Methods
References
Part II. The Determination of Molecular Pattern
3. Optical Rotation
3.1. Introduction
3.2. Conventions
3.3. Experimental Methods
3.4. Principles of Optical Rotation
3.5. Simple Acyclic Compounds
3.6. Carbohydrates
3.7. Steroids
3.8. Triterpenoids
3.9. Diterpenoids
3.10. Other Groups of Compounds
References
4. Ultraviolet and Visible Light Absorption
4.1. Introduction
4.2. Fundamental Concepts and Symbols
4.3. Experimental Methods and Evaluation of Data
4.4. Survey of Data
4.5. General Applications to Structural Analysis
4.6. Special Applications
References
5. Infrared Light Absorption
5.1. Introduction
5.2. Experimental Methods
5.3. General Applications
5.4. Applications to the Study of Macromolecules
References
6. Raman Spectra
6.1. Introduction
6.2. Experimental Methods
6.3. Survey of Data
6.4. Applications to the Determination of Structure
6.5. Determination of Thermodynamic Properties
6.6. Conclusion
References
7. Magnetic Susceptibilities
7.1. The Theory of Magnetic Susceptibility
7.2. Applications to the Study of Organic Compounds. Static Fields
7.3. Applications to the Study of Organic Compounds. Alternating Fields
References
Part III. The Determination of Molecular Fine-Structure
8. Surface Films
8.1. Introduction
8.2. The Technique of Surface Film Measurements
8.3. The Relation Between the Structure of Organic Molecules and the Mechanical Properties of Their Surface Films
8.4. The Relation Between the Structure of Organic Molecules and the Surface Potentials of Their Monolayers
8.5. Applications to the Determination of Structure
References
9. Dipole Moments
9.1. Introduction
9.2. The Theory and Practice of Measuring Electric Dipole Moments
9.3. Applications of Electric Dipole Moments to Simple Stereochemical Problems
9.4. Electric Dipole Moments and Electron Distribution
9.5. Applications of Electrical Dipole Moments to Complex Stereochemical Problems
9.6. Electric Dipole Moments and Molecular Interactions
9.7. Concluding Remarks
References
10. Electron Diffraction
10.1. Introduction
10.2. Instrumentation
10.3. The Theory of Electron Diffraction
10.4. The Analysis of Electron Diffraction Patterns
10.5. Applications to Organic Compounds
References
11. X-Ray Diffraction
11.1. Principles of X-Ray Diffraction
11.2. The Phase Problem
11.3. Quantitative Measurements of Bond Lengths and Valency Angles in Known Structures
11.4. Applications to Unknown and Partially Unknown Structures
11.5. Intermolecular Interactions
References
12. Microwave Spectroscopy
12.1. Introduction
12.2. Principles of Rotational Spectra
12.3. Experimental Methods
12.4. Applications to the Determination of Structure
12.5. Individual Molecules
References
13. Thermodynamic Properties
13.1. Introduction
13.2. Thermodynamic Functions
13.3. Determination of Structure from Heat Capacity and Entropy
13.4. Aliphatic Hydrocarbons
13.5. Alicyclic Hydrocarbons
13.6. Functional Derivatives
13.7. Determination of Structure from Heats of Formation. Bond Energies and Resonance Energies
References
14. Dissociation Constants
14.1. Introduction
14.2. The Strengths of Protonic Acids and Bases
14.3. The Dissociation of Molecular Addition Compounds
14.4. The Application of Dissociation Constants to the Determination of the Structures of Natural Products and Related Compounds
References
15. Reaction Kinetics
15.1. Introduction
15.2. Principles of Reaction Kinetics
15.3. Determination of Electron Distribution
15.4. The Detection and Distinction of Structural Units
15.5. Determination of Stereochemical Configuration and Conformation
15.6. Investigation of Unstable Intermediates
15.7. Investigation of Inter- and Intra-Molecular Complexes
References
16. Wave-Mechanical Theory
16.1. Introduction
16.2. Types of Bonds
16.3. Valence-Bond Treatment of Aromatic Systems
16.4. The Molecular-Orbital Method
References
Author Index
Subject Index
- Edition: 1
- Latest edition
- Published: January 1, 1955
- Language: English
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