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Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine
- 1st Edition - August 4, 2022
- Editors: Alok Pandya, Rajesh S. Bhosale, Vijai Singh
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 8 4 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 8 5 - 3
Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show… Read more
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Request a sales quoteDesign, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning.
- Provides a basic understanding of how to design, and implement various self-assembled nanobiomaterials
- Covers principles implemented in the constructions of novel nanostructured materials
- Offers many applications of self-assemblies in fluorescent biological labels, drug and gene delivery, bio-detection of pathogens, detection of proteins, probing of DNA structure, tissue engineering, and many more
Researchers, students, industrialists, policymakers and stakeholders, nanobiotechnologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- About the editors
- Foreword
- Preface
- Acknowledgments
- Chapter 1. An introduction of self-assembled nanobiomaterials and their applications
- Abstract
- 1.1 Introduction
- 1.2 Application of self-assembled nanobiomaterials
- 1.3 Conclusion
- Acknowledgments
- References
- Chapter 2. Design and construction of bioinspired supramolecular self-assembled nanostructures
- Abstract
- 2.1 Introduction
- 2.2 Self-assembled proteins
- 2.3 Viral particles
- 2.4 Protein engineering in self-assembled nanostructures
- 2.5 Conclusions
- Acknowledgments
- References
- Chapter 3. Design and construction of amino acids, peptides and proteins-based self-assembled nanostructures
- Abstract
- Graphical abstract
- 3.1 Introduction
- 3.2 Role of non-covalent interactions in self-assembly
- 3.3 Nanostructures from bioinspired building blocks
- 3.4 Conclusion and perspectives
- Acknowledgments
- Conflicts of interest
- References
- Chapter 4. Recent development in chiral self-assembly of porphyrin and protoporphyrin IX molecular architectures
- Abstract
- Graphical abstract
- 4.1 Introduction
- 4.2 Chiral self-assembling system based on substituted porphyrin
- 4.3 Chirality induction in porphyrin-assemblies
- 4.4 Porphyrin chiral assembly and disassembly
- 4.5 Chiral self-assembly of porphyrin induced by chiral surfactants
- 4.6 Chiral assembly of biosurfactant functionalized porphyrin
- 4.7 Chiral memory of porphyrin chromophores
- 4.8 Protoporphyrin IX-based chiral supramolecular assembly
- 4.9 Future prospectus
- Acknowledgments
- References
- Chapter 5. Design and construction of arlene diimide based self-assembled nanostructures
- Abstract
- Graphical abstract
- 5.1 Introduction
- 5.2 Napthalene diimide based self-assembled nanostructures
- 5.3 Naphthalene diimide based donor-acceptor nanostructures
- 5.4 Perylene diimide based self-assembled nanostructures
- 5.5 Perylene diimide based donor-acceptor nanostructures
- 5.6 Conclusion
- Acknowledgments
- References
- Chapter 6. Self-assembled functional materials of aggregation-induced emission active molecules
- Abstract
- Graphical Abstract
- 6.1 Introduction
- 6.2 Self-assembled aggregate induced emission active nanoparticles
- 6.3 Self-assembled aggregate induced emission active vesicles, micelles, and nanosheets
- 6.4 Self-assembled aggregate induced emission active nanotubes
- 6.5 Self-assembled aggregate induced emission active nanowires and rods
- 6.6 Self-assembled aggregate induced emission active helical fibers, ribbons, and column
- 6.7 Self-assembled nanocubes and sphere and caterpillar
- 6.8 Conclusion and prospects
- Acknowledgments
- References
- Chapter 7. Design and construction of amphiphilic and bolaamphiphilic material based self-assembled micellar nanostructures
- Abstract
- Graphical abstract
- 7.1 Introduction
- 7.2 Amphiphiles for supramolecular self-assembly
- 7.3 Bolaamphiphile
- 7.4 Outlook
- Acknowledgments
- References
- Chapter 8. Self-assembled living materials and their applications
- Abstract
- 8.1 Introduction
- 8.2 Natural self-assembled living materials
- 8.3 Engineered self-assembled living materials and their applications
- 8.4 Conclusion and future perspective
- Acknowledgments
- References
- Chapter 9. 3D bioprinting: overview and recent developments
- Abstract
- 9.1 Introduction
- 9.2 Modes of 3D printing in tissue engineering
- 9.3 Bioinks
- 9.4 Potential application in various fields
- 9.5 Conclusion and future perspective
- Acknowledgment
- References
- Chapter 10. Self-assembled peptides and proteins for biomedical applications
- Abstract
- Graphical abstract
- 10.1 Introduction
- 10.2 Role of non-covalent interactions and external factors in self-assembly
- 10.3 Therapeutical applications of self-assembled peptides
- 10.4 Therapeutical applications of self-assembled proteins
- 10.5 Conclusion and perspectives
- Acknowledgments
- Conflicts of Interest
- References
- Chapter 11. Design and construction of protein and peptide-based self-assembled nanostructures
- Abstract
- 11.1 Introduction
- 11.2 Short peptide-based nanostructures
- 11.3 Bio-templated nanostructures
- 11.4 Scaffold forming self-assembled nanostructures
- 11.5 Protein-based self-assembled nanostructures as nano-carriers
- 11.6 Bioinspired-bioderived materials: modified microbial nanowires, modified biofilms
- 11.7 Conclusion
- References
- Chapter 12. Self-assembled nanomaterials for drug delivery
- Abstract
- 12.1 Introduction
- 12.2 Conclusion and perspectives
- References
- Chapter 13. Carbon nanotubes and graphene nanomaterials for biomedical applications
- Abstract
- 13.1 Introduction
- 13.2 Carbon-based nanomaterials for biomedical applications
- 13.3 Graphene-based nanomaterials for biomedical applications
- 13.4 Graphene quantum dots
- 13.5 Toxic effects of carbon and graphene-based nanomaterials
- 13.6 Conclusion
- Acknowledgment
- References
- Chapter 14. DNA/RNA-based self-assemblies for bio-sensing
- Abstract
- 14.1 Introduction
- 14.2 Fluorescence-based nucleic acid biosensors
- 14.3 Nanoparticle-based
- 14.4 Gel electrophoresis-based
- 14.5 Atomic force microscopy-based
- 14.6 Application of DNA/RNA based nanosensor in biology and medicine
- 14.7 Concluding remarks
- 14.8 Competing interests
- References
- Chapter 15. Self-assembled nanomaterials for cleansing and bioremediation
- Abstract
- 15.1 Introduction
- 15.2 Self-assembly processes in nanomaterials
- 15.3 Role of nanomaterials in cleansing and bioremediation
- 15.4 Conclusion
- References
- Chapter 16. Bio-interfacial DNA self-assemblies for biomedical applications
- Abstract
- Graphical abstract
- 16.1 Chemical and physical principles for DNA self-assembly
- 16.2 Extracellular DNA self-assemblies for biomedical applications
- 16.3 Cell-interfacial DNA self-assemblies for biomedical applications
- 16.4 Intracellular DNA self-assemblies for biomedical applications
- 16.5 Summary and outlook
- References
- Chapter 17. DNA nanodevices in nanomedicine and therapeutics
- Abstract
- Graphical abstract
- 17.1 Introduction
- 17.2 DNA nanodevices
- 17.3 Cargo loaded DNA based nanocarriers in biological uptake and delivery
- 17.4 Applications of DNA nanodevices in nanomedicine
- 17.5 Conclusions, challenges, and future perspective
- Acknowledgments
- References
- Index
- No. of pages: 314
- Language: English
- Edition: 1
- Published: August 4, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780323909846
- eBook ISBN: 9780323909853
AP
Alok Pandya
Dr. Alok Pandya is an innovator, interdisciplinary researcher, and academic leader specializing in the development of personalized biosensors for point-of-care/need diagnostics and rapid disease detection. His work focuses on developing advanced biosensing technologies for real-time health monitoring. Currently serving as an Associate Professor at the School of Applied Science and Technology, Gujarat Technological University, he brings over 11 years of research experience dedicated to biosensor-driven rapid diagnostics. Before joining GTU, Dr. Pandya spent 8 years as an Assistant Professor at the Institute of Advanced Research (IAR) and 3 years as a Research Associate at Ahmedabad University. He has also been a Visiting Professor at the University of California, San Diego, conducting research on wearable biosensors, and an Entrepreneurial Lead under the US National Science Foundation’s I-Corps™ program, gaining expertise in medical innovation and technology commercialization. A researcher and technologist, Dr. Pandya has published 60+ research articles, authored 5 books & 12+ book chapters, and holds 5 granted patents. His work has secured national and international funding to advance biomedical and forensic diagnostic technologies. He has been honored with prestigious awards, including the SERB-International Research Experience Award, the SERB Young Scientist Award, and the IAR Research Excellence Award. Dr. Pandya has developed cutting-edge biosensing platforms for rapid AMR detection, cardiovascular disease diagnostics, plant pathogen identification, and forensic body fluid analysis. With global research collaborations spanning France, the USA, and India, Dr. Pandya continues to drive innovation in biosensor technology, translating scientific discoveries into real-world applications for precision diagnostics and personalized healthcare.
Affiliations and expertise
School of Applied of Science and Technology, Gujarat Technological technology, AhmedabadRB
Rajesh S. Bhosale
Dr. Rajesh S. Bhosale is an Associate Professor at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He did his PhD (2009) from University of Geneva (Switzerland) under the supervision of Prof. Stefan Matile. Thereafter, he did first post-doctoral research as SNSF postdoctoral fellow from top institutes of World i.e. MIT-Massachusetts Institute of Technology, Cambridge, USA in the group of Prof. Timothy M. Swager and second post-doctoral research as DFG postdoctoral fellow from FRIAS-Freiburg Institute for Advanced Studies, Germany in the group of Prof. Aurelio Mateo-alonso. Where he was excelled in challenging multistep chemical synthesis, electrochemical, photophysical and self-assembly properties study of small molecules, macromolecules and polymer chromophoric systems. He also served as RMIT research associate in the group of Prof. M. Lakshmi Kantam at CSIR-IICT, Hyderabad and in July 2015 he becomes a CSIR scientist pool officer. His research interests are focused on building AIE active novel molecules.
Affiliations and expertise
Associate Professor, Department of Chemistry, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, IndiaVS
Vijai Singh
Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.
Affiliations and expertise
Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, IndiaRead Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine on ScienceDirect