LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering
- 1st Edition - October 9, 2024
- Authors: Dipankar Chattopadhyay, Beauty Das
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 6 1 1 4 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 8 3 8 - 7
Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering covers core elements of scaffold design, from properties and characterization of polymeric… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteDesign, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering covers core elements of scaffold design, from properties and characterization of polymeric scaffolds to fabrication techniques and the structure-property relationship. Particular attention is given to the cell-scaffold interaction at the molecular level, helping the reader understand and adapt scaffold design to improve biocompatibility and function. The book goes on to discuss a range of tissue engineering applications for polymeric scaffolds, including bone, nerve, cardiac and fibroblast tissue engineering. This is an important, interdisciplinary work of relevance to materials scientists, polymer scientists, biomedical engineers, and those working regenerative medicine.
- Helps the reader determine the most appropriate polymer for scaffold design by characterization, properties and structure-property relationship
- Discusses material-cell interactions at the molecular level, aiding in determining suitability
- Covers core elements of scaffold design, including fabrication techniques
Researchers and postgraduate students in the fields of materials science, biomedical engineering, biotechnology, and tissue engineering
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Chapter 1. A brief introduction to tissue engineering
- Abstract
- 1.1 Importance of tissue engineering
- 1.2 Progress in tissue engineering
- 1.3 Principle of tissue engineering
- Acknowledgment
- References
- Chapter 2. Importance of scaffold in tissue engineering
- Abstract
- 2.1 Scaffold: the most important triad of tissue engineering
- 2.2 Function of a scaffold
- References
- Chapter 3. Scaffold' properties and materials used in scaffold designing
- Abstract
- 3.1 Properties of a scaffold
- 3.2 Materials used for scaffold fabrication: advantages and disadvantages
- References
- Chapter 4. Polymer in scaffold designing
- Abstract
- 4.1 Inevitable role of polymers in tissue engineering
- 4.2 Types of polymer used in tissue engineering
- 4.3 Types of scaffold: implantable and injectable polymeric scaffold
- References
- Chapter 5. Fabrication of a polymeric scaffold
- Abstract
- 5.1 Solvent casting and particulate leaching
- 5.2 Gas foaming
- 5.3 Phase separation
- 5.4 Melt molding
- 5.5 Freeze drying
- 5.6 Emulsion freeze drying
- 5.7 Rapid prototyping
- 5.8 Biomodification of a scaffold
- References
- Chapter 6. Role of the polymeric structure and nanocomposites in tissue engineering
- Abstract
- 6.1 Structural aspects of the polymer in tissue engineering
- 6.2 Linear versus branched polymer at the biointerfacial interaction
- 6.3 Role of polymeric nanocomposites in tissue engineering
- References
- Chapter 7. Structure–property relationship in a polymer/nanocomposite-based scaffold
- Abstract
- 7.1 Size
- 7.2 Shape
- 7.3 Charge
- 7.4 Surface topography
- 7.5 Molecular weight
- 7.6 Crystallinity
- 7.7 Wettability (hydrophobicity and hydrophilicity)
- 7.8 Mechanical properties
- 7.9 Flexibility
- 7.10 Porosity
- 7.11 Chemical functionality
- 7.12 Material stability
- References
- Chapter 8. Characterization of polymeric scaffolds
- Abstract
- 8.1 Physicomechanical characterization
- 8.2 Chemical characterization
- 8.3 Morphological characterization
- 8.4 Surface characterization
- 8.5 Thermal characterization
- 8.6 Biological characterization: in vivo and in vitro studies
- 8.7 In vitro cytotoxicityand hematocompatibility assessment
- 8.8 Cell adhesion/spreading assay
- 8.9 In vitro immunocompatibility assay
- 8.10 In vivo assessment of biocompatibility and inflammatory response
- References
- Chapter 9. Tissue engineering approaches
- Abstract
- 9.1 Introduction
- 9.2 Cell-seeded scaffold-based tissue engineering approach
- 9.3 Acellular scaffold-based tissue engineering approach
- 9.4 Conclusion
- References
- Chapter 10. Tissue engineering applications
- Abstract
- 10.1 Introduction
- 10.2 Musculoskeletal tissue regeneration
- 10.3 Bone tissue engineering
- 10.4 Cartilage tissue engineering
- 10.5 Corneal tissue engineering
- 10.6 Nerve cell tissue engineering
- 10.7 Wound healing/skin tissue engineering
- 10.8 Cardiac tissue engineering
- 10.9 Hepatic tissue engineering
- 10.10 Tissue engineering based drug delivery
- 10.11 Conclusion
- References
- Chapter 11. Cell–polymeric scaffold interaction
- Abstract
- 11.1 Introduction
- 11.2 Cell surface receptors for cell–extracellular matrix interaction
- 11.3 Biointerfacial interaction with the polymer
- 11.4 Biointerfacial interaction with nanocomposites
- 11.5 Conclusion
- References
- Chapter 12. Current research technology and practical applicability
- Abstract
- 12.1 Current research technologies
- 12.2 Practical applicability
- 12.3 Conclusion
- References
- Chapter 13. Therapeutical and clinical approaches
- Abstract
- 13.1 Introduction
- 13.2 Importance of clinical studies
- 13.3 Clinical advancements in tissue engineering
- 13.4 Basic consideration in clinical tissue engineering
- 13.5 Preclinical to clinical trial
- Acknowledgement
- References
- Index
- No. of pages: 404
- Language: English
- Edition: 1
- Published: October 9, 2024
- Imprint: Woodhead Publishing
- Paperback ISBN: 9780323961141
- eBook ISBN: 9780323958387
DC
Dipankar Chattopadhyay
Prof. Dipankar Chattopadhyay is an eminent professor currently working in the Department of Polymer Science & Technology, University of Calcutta, India since 2006 and also a former HOD. Earlier, he worked as a lecturer at the Vidhyasagar University and Shahid Bhagat Singh College, Punjab, India. He obtained his B.Tech in Plastics & Rubber Technology from University of Calcutta, India and M.Tech in Polymer Science and Engineering, IIT, New Delhi with Ph.D. (Polymer Science) from the IACS, India. He is an experienced research professional with expertise in polymers nanocomposites, biomaterials, and nanomaterials. He has ~22 years of research experience with completed 10 research project and collaborative projects with industries. He is an active reviewer for various Journals and supervised >20 scholars and five post-doctorate students. He has 127 publications and has 3 patents. He is an Executive Member in the Society for Polymer Science, India; MRSI, Calcutta Chapter and many more.
Affiliations and expertise
Professor, Department of Polymer Science and Technology, University Colleges of Science and Technology, University of Calcutta, IndiaBD
Beauty Das
Dr. Beauty Das completed her M.SC in Biotechnology from Utkal University, India and B.Sc in Zoology from Dibrugarh University, India with distinction. She completed her Ph.D in 2005 from Tezpur University on the topic of polymer nanocomposite based tissue engineering. She has more than 10 years of experience in this intriguing topic by employing polymers, hydrogels and nanocomposites. Currently she is working as a DST Inspire Faculty in University of Calcutta, India and conducting research on tissue engineering approaches to treat Alzheimer’s disease by enhancing neuro-regeneration. She has 6 years of post-doctoral experience on polymeric biomaterials. She has published more than 15 articles and has contributed several book chapters in this area.
Affiliations and expertise
DST Inspire Faculty, Department of Polymer Science and Technology, University Colleges of Science and Technology, University of Calcutta, IndiaRead Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering on ScienceDirect