Dermatopathology
- 4th Edition - November 18, 2024
- Imprint: Elsevier
- Authors: Dirk M. Elston, Tammie C. Ferringer, Christine Ko, Whitney A. High, David J. DiCaudo
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 3 0 5 9 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 3 1 3 8 - 0
Using an enjoyable, easy-to-understand approach, Dermatopathology, Fourth Edition, combines online lectures and vast labeled image collections both in print and online to pro… Read more
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Request a sales quoteUsing an enjoyable, easy-to-understand approach, Dermatopathology, Fourth Edition, combines online lectures and vast labeled image collections both in print and online to provide a uniquely effective learning package in this challenging subspecialty. Dr. Dirk M. Elston, Dr. Tammie Ferringer and colleagues walk you through the “must-know” points of each topic, making dermatopathology easier to understand. It’s an ideal resource for exam and board preparation and for mastering efficient, accurate diagnoses of the most important common dermatologic findings seen in practice.
- Uses an outline atlas format with ample visuals, key points, and pearls
- Includes abundant high-resolution histopathology examples with labels and pointers highlighting key aspects of each slide, providing additional clarity
- Features 27 lectures—more than 8 hours of targeted teaching that take you through the must-know elements of each topic in a dynamic, engaging manner
- Contains expanded coverage of soft tissue tumors, and new entities such as acantholytic dyskeratoma, borrelial disease, acute generalized exanthematous pustulosis (AGEP), acral erythema of chemotherapy, epithelioid histiocytoma, cellular digital fibroma, nuchal type fibroma, elephantiasis nostras verrucosa, ganglion, ossifying fibromyxoid tumor of soft parts, aggressive angiomyxoma, alveolar soft part sarcoma, and much more
- Offers extensive, visually stunning images in print with bonus materials online, including 2,500 virtual infectious disease slides, a soft tissue tumor atlas with 300 images, a lymphoma atlas, and more; print atlas includes more than 1,300 images (300 new to this edition)
- Provides new flashcards online to test your knowledge and identify areas for further review
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
Dermatopathology, dermatology
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Online Lectures and Atlas Materials
- Preface
- List of Contributors
- Acknowledgments
- Dedications
- Chapter 1. The basics: diagnostic terms, skin anatomy, and stains
- Glossary of terms
- Acantholysis
- Acanthosis
- Anaplasia
- Apoptosis (pronounced apohtosis)
- Arborizing
- Asteroid body
- Atrophy
- Ballooning degeneration
- Caterpillar body
- Civatte/colloid bodies
- Collagen entrapment
- Cornoid lamellae
- Corps ronds/grains/dyskeratosis
- Cowdry A body
- Cowdry B body
- Crust
- Donovan body
- Dutcher body
- Effacement
- Eosinophilic spongiosis
- Epidermolytic hyperkeratosis
- Epidermotropism
- Erosion
- Exocytosis
- Festooning
- Flame figure
- Foam cell
- Follicular mucinosis
- Granulomatous
- Grenz zone
- Guarnieri body
- Henderson–Paterson body
- Hypergranulosis/hypogranulosis
- Hyperpigmentation/hypopigmentation
- Interface
- Kamino body
- Karyorrhexis
- Koilocytes
- Leishman–Donovan body
- Lentiginous epidermal hyperplasia
- Lentiginous melanocytic growth pattern
- Leukocytoclasia
- Lichenoid dermatitis
- Lichenoid infiltrate
- Medlar body
- Metachromasia
- Michaelis–Gutmann body
- Munro microabscess
- Necrobiosis
- Negri body
- Orthokeratosis
- Pagetoid cells
- Pagetoid scatter
- Palisading
- Papillary mesenchymal body
- Papillomatosis
- Parakeratosis
- Pigment incontinence
- Pleomorphism
- Psammoma body
- Pseudoepitheliomatous hyperplasia (PEH)
- Pseudohorn cyst
- Reticular degeneration
- Reticulated
- Russell body
- Schaumann body
- Shadow cells
- Spongiform pustule of Kogoj
- Spongiosis
- Squamotization (or squamatization)
- Squamous eddies
- Storiform
- Vacuolar change
- Verocay body
- Villus
- Normal skin anatomy
- Scalp skin
- Facial skin
- Skin of the trunk
- Areolar skin
- Acral/Volar skin
- Mucosa
- Nasal turbinate
- Fetal skin
- Hair anatomy
- Infundibulum
- Isthmus
- Stem
- Adamson fringe
- Bulb
- Nail anatomy
- Nail bed
- Framing portion
- Ensheathing portion
- Cuticle
- Hyponychium
- Solehorn
- Nail matrix
- Lunula
- Types of keratinization of the nail
- Onychokeratinization (no granular layer)
- Onycholemmal keratinization
- Epidermoid keratinization
- Types of inflammatory cells
- Dermal dendrocyte
- Giant cell
- Types
- Histiocyte
- Langerhans cell
- Lymphocyte
- Mast cell
- Neutrophil
- Eosinophil
- Plasma cell
- Histochemical stains
- Connective tissue stains
- Masson trichrome stain
- Verhoeff–Van Gieson stain
- Mast cell stains
- Toluidine blue
- Giemsa
- Leder stain (naphthol ASD chloroacetate esterase)
- Carbohydrate stains
- PAS (periodic acid–Schiff)
- Alcian blue
- Colloidal iron
- Toluidine blue
- Mucicarmine
- Amyloid
- Congo red
- Thioflavin T
- Crystal violet
- Iron
- Prussian blue (Perls stain)
- Melanin
- Fontana–Masson
- Calcium
- Von Kossa
- Alizarin red
- Lipids
- Oil red O
- Sudan black
- Osmium tetroxide
- Bacteria
- Brown–Hopps
- Fungi
- PAS (periodic acid–Schiff)
- GMS (Grocott’s methenamine silver)
- Mycobacteria
- Ziehl–Neelsen acid-fast stain; Fite acid-fast stain; Kinyoun’s acid-fast stain
- Auramine–rhodamine
- Spirochetes
- Warthin–Starry; Dieterle; Steiner (modified Dieterle stain)
- Other “special” stains
- Giemsa
- Immunohistochemical stains
- Epithelial markers
- AE1/AE3
- CK polyclonal keratin (pankeratin)
- CK903(34betaE12)
- CK5/6
- p63/p40
- p40
- CAM5.2
- CK7
- CK20
- Ber-EP4
- Epithelial membrane antigen (EMA)
- Other important markers of carcinoma
- Carcinoembryonic antigen (CEA)
- Adipophilin
- p16
- Organ-specific markers
- CDX2, villin, SATB2
- GATA3
- NKX3.1
- PAX-8
- Thyroid transcription factor (TTF-1)
- Mesenchymal markers
- Desmin (see Table 1.2)
- Smooth muscle actin (SMA) (see Table 1.2)
- Calponin
- CD34
- Factor XIIIa
- CD31
- D2-40 (podoplanin)
- ERG
- GLUT1 (glucose transporter)
- Vimentin
- Neuroectodermal markers
- S100
- S100A6 (calcyclin)
- HMB-45
- Melan-A and Mart-1
- p75 (nerve growth factor receptor)
- Microphthalmia-associated transcription factor (MITF)
- Sox-10
- PRAME (preferentially expressed antigen in melanoma)
- Neuroendocrine markers
- Neuron-specific enolase (NSE)
- Chromogranin
- Synaptophysin
- INSM-1
- Hematopoietic markers
- CD1a
- CD3
- CD4
- CD5
- CD7
- CD8
- CD10 (CALLA)
- CD20
- CD21
- CD30 (Ki-1, BERH2)
- CD43 (Leu-22)
- CD45Ra (LCA)
- CD45Ro (UCHL-1)
- CD56
- CD68 (KP-1)
- CD79a
- CD117 (c-Kit)
- CD123
- CD138 (syndecan-1)
- CD163
- Langerin (CD207)
- Myeloperoxidase
- ALK-1
- Kappa/lambda
- BCL2
- Multiple myeloma oncogene-1 (MUM-1)
- BetaF1
- Panels
- Proliferation markers
- Mib-1 (Ki-67)
- pHH3
- Infectious disease markers
- Transport media
- Routine
- Electron microscopy
- Immunofluorescence
- Chapter 2. Benign tumors and cysts of the epidermis
- Benign acanthomas
- Seborrheic keratoses
- Acanthotic seborrheic keratosis
- Hyperkeratotic seborrheic keratosis
- Reticulated seborrheic keratosis (adenoid seborrheic keratosis)
- Clonal seborrheic keratosis
- Pigmented seborrheic keratosis
- Irritated seborrheic keratosis
- Inflamed seborrheic keratosis
- Key Features
- Key Features
- Key Features
- Melanoacanthoma
- Clear cell acanthoma (pale cell acanthoma)
- Large cell acanthoma
- Inverted follicular keratosis (IFK)
- Warty dyskeratoma
- Acantholytic dyskeratoma
- Acantholytic acanthoma
- Epidermolytic acanthoma
- Epidermal nevi
- Common epidermal nevus
- Inflammatory linear verrucous epidermal nevus (ILVEN)
- Key Features
- Cysts
- Epidermoid cyst (epidermal inclusion cyst, infundibular cyst)
- Epidermoid cyst with pilomatrical differentiation
- Vellus hair cyst
- Dermoid cyst
- Pilar cyst (trichilemmal cyst, isthmus catagen cyst)
- Proliferating pilar cyst
- Key Features
- Branchial cleft cyst
- Bronchogenic cyst
- Steatocystoma (simple sebaceous duct cyst)
- Median raphe cyst
- Cutaneous ciliated cyst
- Thyroglossal duct cyst
- Chapter 3. Malignant tumors of the epidermis
- Actinic keratosis
- Actinic cheilitis
- Acantholytic actinic keratosis
- Lichenoid actinic keratosis
- Hypertrophic actinic keratosis
- Bowenoid actinic keratosis
- Bowen’s disease (squamous cell carcinoma in situ)
- Invasive squamous cell carcinoma
- Verrucous carcinoma
- Spindled squamous cell carcinoma
- Keratoacanthoma
- Regressing keratoacanthoma
- Basal cell carcinoma (BCC)
- Superficial multifocal BCC
- Nodular BCC
- Micronodular BCC
- Morpheaform BCC
- Infiltrative BCC
- Infundibulocystic BCC
- Fibroepithelioma of Pinkus
- Adenoid BCC
- Paget’s disease
- Lymphoepithelioma-like carcinoma
- Chapter 4. Pilar and sebaceous neoplasms
- Pilar neoplasms
- Pilomatricoma (calcifying epithelioma of Malherbe)
- Pilomatrical carcinoma
- Trichoblastoma
- Trichoepithelioma
- Desmoplastic trichoepithelioma
- Paisley-tie tumors
- Lymphadenoma (adamantinoid trichoblastoma)
- Fibrofolliculoma
- Birt–Hogg–Dubé syndrome
- Trichofolliculoma
- Trichoadenoma
- Basaloid follicular hamartoma
- Dilated pore of Winer
- Pilar sheath acanthoma
- Trichilemmoma
- Desmoplastic trichilemmoma
- Tumor of the follicular infundibulum
- Panfolliculoma
- Hair mantle
- Sebaceous neoplasms
- Reticulated acanthoma with sebaceous differentiation
- Nevus sebaceus of Jadassohn (organoid nevus)
- Postpubertal nevus sebaceus of Jadassohn
- Prepubertal nevus sebaceus of Jadassohn
- Sebaceous hyperplasia
- Sebaceoma, sebaceous adenoma, and sebaceous epithelioma
- Sebaceous carcinoma
- Chapter 5. Sweat gland neoplasms
- Cylindroma (turban tumor)
- Spiradenoma
- Tender tumors: BANGLE
- Spiradenocarcinoma
- Syringocystadenoma papilliferum (syringadenoma papilliferum)
- Hidradenoma papilliferum
- Papillary digital carcinoma (aggressive digital papillary adenocarcinoma)
- Mucinous carcinoma
- Syringoma
- Clear cell syringoma
- Microcystic adnexal carcinoma
- Sclerosing sweat duct carcinoma
- Hidrocystoma
- Endocrine mucin-producing sweat duct carcinoma of the eyelid
- Mixed tumor (chondroid syringoma)
- Small tubular type (chondroid syringoma type)
- Branching alveolar type
- Cutaneous myoepithelioma
- Malignant mixed tumor (malignant chondroid syringoma)
- Acrospiromas
- Poroma
- Hidroacanthoma simplex
- Dermal duct tumor
- Nodular hidradenoma
- Clear cell hidradenoma
- Malignant acrospiroma (porocarcinoma, malignant poroma)
- Syringofibroadenoma of Mascaro
- Papillary “eccrine” adenoma (tubular apocrine adenoma)
- Adenoid cystic carcinoma
- Eccrine angiomatous hamartoma
- Benign intraductal adenoma of the nipple
- Supernumerary nipple (polythelia)
- Chapter 6. Melanocytic neoplasms
- Solar lentigo
- Ink spot lentigo
- Melanotic macule
- Benign melanocytic nevus
- Balloon cell nevus
- “Neural” nevus
- Congenital nevus
- Spitz nevus
- Pagetoid intraepidermal Spitz nevus
- Pigmented spindle cell nevus of Reed
- “Special site” nevus
- Acral nevus
- “Ancient” nevus
- Halo nevus
- Blue nevus
- Deep penetrating nevus (WNT-activated melanocytoma)
- Carney’s nevus (epithelioid blue nevus)
- Combined nevus
- Wiesner nevus (benign BAP mutated nevus)
- Benign Clark nevus (“dysplastic” nevus)
- Grading dysplastic nevi
- Management
- Junctional lentiginous nevus
- Recurrent nevus (persistent nevus, pseudomelanoma)
- Nevus of Ota/nevus of Ito
- Mongolian spot
- Malignant melanoma
- Superficial spreading malignant melanoma
- Lentigo maligna
- Lentigo maligna melanoma
- Acral lentiginous maligna
- Spindle cell melanoma
- Desmoplastic melanoma
- Nodular melanoma
- Regressing melanoma
- Metastatic melanoma
- Blue nevus-like melanoma (uveal-type melanoma of skin, animal-type melanoma, equine-type melanoma, “malignant pigmented epithelioid melanocytoma”)
- Clear cell sarcoma
- Chapter 7. Interface dermatitis
- Lichenoid interface dermatitis
- Causes of lichenoid interface dermatitis
- Late-phase (burnt-out) lichenoid dermatitis
- Lichen planus (LP)
- Lichenoid drug eruption
- Benign lichenoid keratosis
- Lichenoid graft-versus-host disease
- Acral erythema of chemotherapy (toxic erythema of chemotherapy, acral erythrodysesthesia)
- Hypertrophic lupus erythematosus
- Dermatomyositis
- Lichenoid regression of lentigo maligna
- Porokeratosis
- Vacuolar interface dermatitis
- Vacuolar interface dermatitis with a lymphocyte in nearly every vacuole
- Mycosis fungoides
- Pityriasis lichenoides et varioliformis acuta (PLEVA)
- Pityriasis lichenoides chronica
- Early stage of benign lichenoid keratosis
- Vacuolar interface dermatitis with vacuoles or cell death out of proportion to lymphocytes
- Lupus erythematosus
- Polymorphous light eruption
- Lichen striatus
- Syphilis
- Erythema multiforme
- Toxic epidermal necrolysis
- Paraneoplastic pemphigus
- Fixed drug eruption
- Graft-versus-host disease (GvHD)
- Still’s disease
- Chapter 8. Psoriasiform and spongiotic dermatitis
- Psoriasis
- Plaque psoriasis
- Pustular psoriasis
- Guttate psoriasis
- Inflammatory linear verrucous epidermal nevus (ILVEN)
- Mycosis fungoides
- Syphilis
- Diagnoses
- Body locations that recruit plasma cells
- Necrolytic erythemas/nutritional deficiency dermatitis
- Granular parakeratosis
- Porokeratosis
- Acute spongiotic dermatitis
- Seborrheic dermatitis
- Subacute spongiotic dermatitis
- Common causes of spongiotic dermatitis
- Chronic dermatitis (lichen simplex chronicus)
- Pityriasis rosea
- Spongiotic pigmented purpuric eruption (PPE)
- Stasis dermatitis
- Spongiotic dermatitis with intraepidermal eosinophils
- Zoon balanitis
- Pityriasis rubra pilaris
- Toxic shock syndrome
- Chapter 9. Blistering diseases
- Introduction
- Subcorneal vesiculobullous disorders
- Pemphigus foliaceus
- Subcorneal pustular dermatosis (Sneddon–Wilkinson disease) and IgA pemphigus
- Acute generalized exanthematous pustulosis
- Intraepidermal vesiculobullous disorders
- Pemphigus vulgaris
- Familial benign chronic pemphigus (Hailey–Hailey disease)
- Keratosis follicularis (Darier disease)
- Transient acantholytic dermatosis (Grover disease)
- Paraneoplastic pemphigus
- Friction blister
- Subepidermal vesiculobullous disorders: pauci-inflammatory subepidermal conditions
- Porphyria cutanea tarda
- Epidermolysis bullosa acquisita
- Toxic epidermal necrolysis/Stevens–Johnson syndrome
- Bullous diabeticorum
- Coma blister
- Inflammatory subepidermal conditions
- Bullous pemphigoid
- Cicatricial pemphigoid
- Dermatitis herpetiformis
- Plaid
- Linear IgA bullous dermatosis
- Bullous fixed drug eruption
- Bullous lupus erythematosus
- Chapter 10. Granulomatous and histiocytic diseases
- Granulomatous patterns
- Palisaded granulomas
- Granuloma annulare
- Interstitial pattern
- Palisading pattern
- “Busy dermis can kill grandma’s sweet niece”
- Actinic granuloma
- Necrobiosis lipoidica
- Rheumatoid nodule
- Lupus miliaris disseminatus faciei (LMDF: acne agminata)
- Necrobiotic xanthogranuloma (NXG)
- Gout
- Reactive granulomatous dermatitis (RGD)
- Sarcoidal granulomas
- Sarcoidosis
- “Naked silly bears can gather in foreign towns”
- Foreign-body granulomas
- Orofacial granulomatosis
- Tuberculoid granulomas
- Crohn disease
- Histiocytoses
- Non-Langerhans cell histiocytosis
- Xanthogranuloma
- Benign cephalic histiocytosis (BCH)
- Reticulohistiocytic granuloma (solitary reticulohistiocytoma)
- Rosai–Dorfman disease (sinus histiocytosis with massive lymphadenopathy)
- Langerhans cell histiocytoses
- Langerhans cell histiocytosis (histiocytosis X)
- Xanthomas
- Xanthelasma
- Tuberous xanthoma
- Eruptive xanthoma
- Verruciform xanthoma
- Other histiocytic processes
- Crystal storing histiocytosis
- Granulomatous slack skin
- Intralymphatic histiocytosis
- Chapter 11. Inflammatory vascular diseases
- Leukocytoclastic vasculitis (LCV)
- Classification of vasculitis
- Large vessel vasculitis
- Giant cell arteritis (temporal arteritis)
- Takayasu arteritis
- Polyarteritis nodosa
- Thrombophlebitis
- Thromboangiitis obliterans (Buerger's disease)
- Medium vessel vasculitis
- Granulomatosis with polyangiitis (formerly Wegener’s granulomatosis)
- Eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome)
- Microscopic polyangiitis
- Rheumatoid vasculitis
- Septic vasculitis
- Small vessel leukocytoclastic vasculitis
- Henoch–Schönlein purpura
- Mixed cryoglobulin disease
- Drug-induced and idiopathic leukocytoclastic vasculitis (idiopathic leukocytoclastic angiitis)
- Unique forms of vasculitis
- Granuloma faciale
- Erythema elevatum diutinum
- Kawasaki disease
- Incidental vasculitis
- Neutrophilic dermatoses
- Sweet’s syndrome (acute febrile neutrophilic dermatosis)
- Other neutrophilic dermatoses
- Pyoderma gangrenosum
- Early lesions
- Late lesions
- Urticaria
- Early lesions of urticaria
- Late lesions of urticaria
- Wells' syndrome (eosinophilic cellulitis)
- Perivascular lymphoid infiltrates
- Pigmenting purpuric eruption
- Gyrate erythemas
- Tumid lupus erythematosus
- Polymorphous light eruption
- Morbilliform drug eruptions
- Lymphoid vasculitis
- Degos' disease (malignant atrophic papulosis)
- Insect bite
- Perniosis
- Occlusive vascular diseases
- Type I cryoglobulinemia
- Cholesterol embolization
- Livedoid vasculopathy (segmental hyalinizing vasculopathy)
- Collagenous vasculopathy
- Stasis change
- Coagulopathy
- Noninflammatory purpura
- Scurvy
- Solar (“senile”) purpura (Bateman or actinic purpura)
- Other noninflammatory purpura
- Chapter 12. Genodermatoses
- Pseudoxanthoma elasticum (PXE)
- Ichthyosis vulgaris
- “I go to campus”
- Epidermolytic ichthyosis (bullous congenital ichthyosiform erythroderma)
- Porokeratotic eccrine ostial dermal duct nevus (PEODDN)
- Lipoid proteinosis (hyalinosis cutis et mucosae, Urbach–Wiethe disease)
- Goltz syndrome (focal dermal hypoplasia, Goltz–Gorlin syndrome)
- Dowling–Degos disease (reticulated pigmented anomaly of the flexures)
- Galli–Galli disease
- Ataxia-telangiectasia (Louis-Bar syndrome)
- BAP1 tumor predisposition syndrome
- Nevoid basal cell nevus syndrome (Gorlin syndrome)
- Incontinentia pigmenti (Bloch–Sulzberger syndrome)
- Vesicular stage
- Verrucous stage
- Pigmented stage
- Subungual tumors
- Epidermolysis bullosa (EB)
- EB simplex
- Junctional EB
- Dystrophic EB
- Mastocytosis
- Chapter 13. Alterations in collagen and elastin
- Elastic
- Elastoma (connective tissue nevus)
- Elastosis perforans serpiginosa
- Elastosis perforans serpiginosa-associated disorders
- Papular elastorrhexis
- Scar
- Anetoderma
- Fibroelastolytic papulosis
- Favre–Racouchot syndrome (nodular elastosis with cysts and comedones)
- Adult colloid milium
- Elastotic nodules of the ear
- Collagenous and elastotic plaques of the hand
- Chronic radiation dermatitis
- Erythema ab igne
- Collagen
- Morphea/scleroderma
- Atrophoderma of Pasini and Pierini
- Linear atrophoderma of Moulin
- Eosinophilic fasciitis (Shulman syndrome)
- Pachydermodactyly
- Sclerodermoid graft-versus-host disease
- Collagenoma (connective tissue nevus)
- Hypertrophic scar
- Keloid
- Acne keloidalis nuchae
- Weathering nodule
- Lichen sclerosus (et atrophicus)
- Acrodermatitis chronica atrophicans
- Aplasia cutis congenita
- Corticosteroid atrophy
- Striae distensae
- Reactive perforating collagenosis
- Chondrodermatitis nodularis helicis
- Chapter 14. Metabolic and deposition disorders
- Mucinoses
- Scleredema (of Buschke)
- Pretibial myxedema
- Generalized myxedema
- Scleromyxedema
- Tumid lupus
- Focal mucinosis
- Mucocele
- Myxoma
- Amyloidosis
- Primary systemic amyloidosis
- Nodular amyloidosis
- Macular amyloid
- Lichen amyloid
- Collagenous papules of the ear (auricular amyloidosis)
- Cutaneous calcification
- Calciphylaxis
- Subepidermal calcified nodule
- Scrotal calcinosis
- Porphyrias
- Erythropoietic protoporphyria (EPP)
- Porphyria cutanea tarda (PCT)
- Nutritional disorders
- Scurvy
- Acrodermatitis enteropathica
- Gout
- Colloid milium
- Oxalosis
- Ochronosis
- Acanthosis nigricans
- Chapter 15. Disorders of skin appendages
- Noninflammatory alopecia
- Pattern alopecia (androgenetic balding)
- Triangular alopecia
- Telogen effluvium
- Trichotillomania (trichotillosis)
- Traction alopecia
- Inflammatory nonscarring alopecia
- Alopecia areata
- Pattern alopecia
- Trichotillomania
- Syphilitic alopecia
- Alopecia mucinosa
- Folliculotropic mycosis fungoides (cutaneous T-cell lymphoma)
- Tinea capitis and Majocchi fungal folliculitis
- Acne vulgaris
- Cicatricial alopecia
- Lupus erythematosus
- Lichen planopilaris (LPP)
- Idiopathic pseudopelade
- Central centrifugal cicatricial alopecia (CCCA)
- Dissecting cellulitis
- Folliculitis decalvans
- Acne keloidalis
- Acute Langerhans cell histiocytosis (histiocytosis X)
- Miliaria
- Neutrophilic eccrine hidradenitis
- Hidradenitis suppurativa
- Apocrine chromhidrosis
- Pseudocyst of the auricle
- Relapsing polychondritis
- Onycholemmal cysts
- Onychomatricoma
- Onychopapilloma
- Onycholemmal carcinoma
- Chapter 16. Panniculitis
- Septal panniculitis
- Erythema nodosum
- Lobular panniculitis
- Lupus panniculitis (lupus profundus)
- Pancreatic panniculitis
- Subcutaneous fat necrosis of the newborn
- Eosinophilic panniculitis
- Causes
- Suppurative and granulomatous panniculitis
- Nodular vasculitis/erythema induratum (EI) of Bazin
- Alpha1-antitrypsin deficiency
- Lipodermatosclerosis (stasis panniculitis)
- Cytophagic histiocytic panniculitis
- Traumatic fat necrosis (including “mobile encapsulated lipoma”)
- Subcutaneous panniculitis-like lymphoma
- Chapter 17. Bacterial, spirochete, and protozoan infections
- Bacterial diseases
- Impetigo
- Bullous impetigo
- Suppurative folliculitis
- Botryomycosis
- Pitted keratolysis
- Erythrasma
- Ecthyma gangrenosum
- Rhinoscleroma
- Chancroid
- Granuloma inguinale
- Malakoplakia
- Leprosy
- Lepromatous leprosy
- Tuberculoid leprosy
- Histoid leprosy
- Leprosy reactions
- Tuberculosis
- Spirochete-mediated diseases
- Syphilitic chancre
- Secondary syphilis
- Tertiary syphilis
- Lyme disease
- Erythema migrans
- Acrodermatitis chronica atrophicans
- Borrelial juxtaarticular nodules
- Rickettsial diseases
- Protozoan diseases
- Leishmaniasis
- Acanthamoeba
- Chapter 18. Fungal infections
- Tinea
- Bullous tinea
- Onychomycosis
- Tinea versicolor
- Candidiasis
- Coccidioidomycosis
- Cryptococcosis
- Blastomycosis
- Paracoccidioides infection (South American “blastomycosis”)
- Histoplasmosis
- “pH girl”
- African histoplasmosis
- Lobomycosis (keloidal blastomycosis)
- Sporotrichosis
- Mycetomas
- Eumycetoma
- Actinomycetomas
- Tinea nigra
- Phaeohyphomycosis
- Chromomycosis (chromoblastomycosis)
- Zygomycosis
- Mucorales infection (mucormycosis)
- Entomophthorales infection (entomophthoromycosis)
- Hyalohyphomycosis (including aspergillosis and fusariosis)
- Protothecosis
- Rhinosporidiosis
- Chapter 19. Viral infections, helminths and arthropods
- Viral infections
- Warts
- Verruca vulgaris
- Myrmecia
- Verruca plana (flat wart)
- Epidermodysplasia verruciformis (EDV)
- Condyloma acuminatum
- Bowenoid papulosis
- Heck disease
- Verrucous cyst (cystic papilloma)
- Herpetic infections
- Herpes simplex
- Herpes zoster (varicella-zoster virus (VZV))
- Chicken pox (VZV)
- Verrucous VZV infection
- Cytomegalovirus
- Pox and parapox infections
- Smallpox (variola)
- M-Pox (Monkey pox)
- Molluscum contagiosum
- Orf and milker’s nodules
- Gianotti–Crosti syndrome
- Hand, foot and mouth syndrome
- Oral hairy leukoplakia
- Oral white sponge nevus (for comparison)
- Viral-associated trichodysplasia (trichodysplasia spinulosa)
- Viral exanthem
- Flukes, tapeworms and roundworms
- Flukes
- Schistosomiasis
- Flatworms
- Sparganosis
- Sparganum proliferum
- Roundworms
- Elephantiasis
- Onchocerciasis
- Onchocercoma
- Onchocerca microfilaria
- Dirofilariasis
- Hookworm
- Pinworm
- Strongyloides
- Gnathostomiasis
- Arthropods
- Scabies
- Bites and stings
- Insect bite
- Insect sting
- Tick
- Tick bite
- Spider bite
- Myiasis
- Tungiasis
- Chapter 20. Fibrous tumors
- Dermatofibroma
- Aneurysmal dermatofibroma (sclerosing haemangioma)
- Fibrous histiocytoma
- Dermatofibroma with monster cells
- Epithelioid histiocytoma
- Multinucleate cell angiohistiocytoma
- Adult myofibroma
- Juvenile myofibroma
- Dermatomyofibroma
- Fibromatosis
- Infantile myofibromatosis
- Juvenile hyaline fibromatosis
- Scar
- Hypertrophic scar
- Keloid
- Metaplastic synovial cyst
- Fibrous hamartoma of infancy
- Infantile digital fibroma (inclusion body fibroma)
- Giant cell tumor of the tendon sheath
- Fibroma of tendon sheath
- Giant cell tumor of the soft tissue
- Elastofibroma dorsi
- Sclerotic fibroma
- Pleomorphic fibroma
- Collagenous fibroma (desmoplastic fibroblastoma)
- Nuchal-type fibroma (collagenosis nuchae)
- Angiofibromas
- Fibrous papule of the face (benign fibrous papule, solitary angiofibroma)
- Acquired digital fibrokeratoma (ADF)
- Cellular digital fibroma
- Superficial acral fibromyxoma (digital-type fibromyxoma)
- Nodular fasciitis
- Cranial fasciitis
- Proliferative fasciitis
- Intravascular fasciitis
- Ischaemic fasciitis (atypical decubital fibroplasia, pseudosarcomatous fasciitis)
- Calcifying aponeurotic fibroma
- Nuchal-type fibroma
- Stromal polyp (pseudosarcomatous polyp)
- Phymatous change
- Elephantiasis nostras verrucosa
- Fibrolipoma
- Ganglion
- PEComas and distinctive dermal clear cell mesenchymal neoplasm (DDCCMN)
- Borderline tumors
- Ossifying fibromyxoid tumor of soft parts
- Desmoid tumor (aggressive fibromatosis)
- Plexiform fibrohistiocytic tumor
- Solitary fibrous tumor
- Aggressive angiomyxoma
- Malignant tumors
- Dermatofibrosarcoma protuberans (DFSP)
- Giant cell fibroblastoma
- Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma
- Fibrosarcoma
- Undifferentiated pleomorphic sarcoma
- Epithelioid sarcoma
- Synovial sarcoma
- Low-grade fibromyxoid sarcoma (LGFMS, Evans tumor, Hyalinizing spindle cell tumor with giant rosettes)
- Alveolar soft part sarcoma
- Chapter 21. Tumors of fat, muscle, cartilage, and bone
- Fat
- Lipoma
- Angiolipoma
- Spindle cell lipoma
- Fibrolipoma
- Pleomorphic lipoma
- Atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS)
- Pleomorphic and myxoid liposarcoma
- Lipoblastoma
- Angiomyolipoma
- Hibernoma
- Nevus lipomatosis superficialis of Hoffmann and Zurhelle
- Lipoatrophy
- Mobile encapsulated lipoma (encapsulated fat necrosis, nodular–cystic fat necrosis)
- Muscle
- Smooth muscle hamartoma
- Leiomyoma
- Piloleiomyoma
- Angioleiomyoma
- Leiomyosarcoma
- EBV-associated smooth muscle tumor
- Rhabdomyomatous mesenchymal hamartoma (striated muscle hamartoma)
- Intramuscular myxoma
- Adult rhabdomyoma
- Rhabdomyosarcoma
- Cartilage and bone
- Osteoma cutis
- Accessory tragus (cartilaginous rest)
- Chondroma
- Chondrosarcoma
- Chordoma
- Subungual exostosis
- Chapter 22. Neural tumors
- Neurofibroma
- Diffuse neurofibroma
- Plexiform neurofibroma
- Schwannoma (neurilemmoma)
- “Ancient” schwannoma
- Neuromas
- Traumatic neuroma
- Epithelial sheath neuroma
- Solitary circumscribed neuroma (palisaded encapsulated neuroma)
- Supernumerary digit (rudimentary polydactyly)
- Merkel cell carcinoma (primary neuroendocrine carcinoma of the skin, trabecular carcinoma)
- Granular cell tumor
- Neurothekeoma
- Nerve sheath myxoma (myxoid neurothekeoma)
- Cellular neurothekeoma
- Malignant peripheral nerve sheath tumor (MPNST) (neurofibrosarcoma, malignant schwannoma)
- Cutaneous ganglioneuroma
- Perineurioma
- Glial heterotopia (nasal glioma)
- Encephalocele
- Meningeal heterotopia (rudimentary meningocele)
- Meningioma
- Ependymoma
- Neuroblastoma
- Chapter 23. Vascular tumors
- Angiokeratoma
- Lymphangioma
- Capillary malformation (nevus flammeus)
- Angioma serpiginosum
- Venous lake
- Glomus tumor
- Glomangioma
- Pyogenic granuloma
- Bacillary angiomatosis
- Cherry angioma
- Infantile hemangioma
- Angiolymphoid hyperplasia with eosinophilia (ALHE)
- Kimura disease
- Intravascular papillary endothelial hyperplasia of Masson (IPEH)
- Arteriovenous malformation (arteriovenous hemangioma)
- Targetoid hemosiderotic hemangioma (hobnail hemangioma)
- Eccrine angiomatous hamartoma
- Glomeruloid hemangioma
- Microvenular hemangioma
- Tufted angioma (angioblastoma)
- Myopericytoma (perivascular myoid tumor)
- PEComa (perivascular epithelioid cell tumor)
- Kaposiform hemangioendothelioma
- Pleomorphic hyalinizing angiectatic tumor (PHAT)
- Hemangiopericytoma
- Spindle cell hemangioma (spindle cell hemangioendothelioma)
- Epithelioid hemangioendothelioma
- Retiform hemangioendothelioma
- Atypical vascular lesion (AVL)
- Angiosarcoma
- Kaposi sarcoma
- Early-patch-stage Kaposi sarcoma
- Later-patch/plaque Kaposi sarcoma
- Nodular Kaposi sarcoma (KS)
- Acroangiodermatitis (“pseudoangiosarcoma”)
- Glomangiosarcoma
- Chapter 24. Cutaneous T-cell lymphoma, NK-cell lymphoma, and myeloid leukemia
- T-cell and NK-cell lymphomas and leukemias
- Mycosis fungoides
- Patch stage
- Plaque stage
- Tumor stage
- Erythrodermic stage
- T-cell and NK-cell lymphomas and leukemias
- Acute myeloid leukemia
- Plasmacytoid dendritic cell neoplasms
- Mycosis fungoides variants
- Folliculotropic mycosis fungoides
- Pagetoid reticulosis
- Granulomatous slack skin
- Rare histopathologic patterns of mycosis fungoides
- Sézary syndrome
- Adult T-cell leukemia/lymphoma (ATLL)
- Primary cutaneous CD30+ lymphoproliferative disorders
- Lymphomatoid papulosis
- Primary cutaneous anaplastic large cell lymphoma
- Type A
- Type B
- Type C
- Type D
- Type E
- LyP with chromosomal rearrangement of DUSP22-IRF4 on 6p25.3
- Subcutaneous panniculitis-like T-cell lymphoma
- Primary cutaneous peripheral T-cell lymphoma, NOS
- Primary cutaneous peripheral T-cell lymphoma, rare subtypes
- Primary cutaneous gamma/delta T-cell lymphoma
- Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma
- Primary cutaneous CD4+ small or medium T-cell lymphoproliferative disorder
- Primary cutaneous acral CD8+ T-cell lymphoproliferative disorder
- Extranodal NK/T-cell lymphoma
- Chronic active EBV infection
- Hydroa vacciniforme lymphoproliferative disorder
- Severe mosquito bite allergy
- Systemic T-cell lymphomas and leukemias with secondary cutaneous involvement
- Nodal T-follicular helper (TFH) cell lymphoma
- T-prolymphocytic leukemia
- Myeloid leukemia
- Blastic plasmacytoid dendritic cell neoplasm
- Chapter 25. B-cell lymphoma and lymphocytic leukemia
- Cutaneous B-cell lymphoproliferative disorders
- Normal lymph node and benign reactive lymphoid hyperplasia
- Primary cutaneous marginal zone lymphoma
- Primary cutaneous follicle center cell lymphoma
- Cutaneous diffuse large B-cell lymphoma, leg type
- EBV+ mucocutaneous ulcer
- Cutaneous diffuse large B-cell lymphoma, other than leg type
- Systemic lymphoproliferative diseases that may present with cutaneous involvement
- Intravascular large B-cell lymphoma
- Chronic lymphocytic leukemia/small lymphocytic lymphoma
- Mantle cell lymphoma
- Burkitt lymphoma
- B-cell lymphoblastic lymphoma/leukemia
- Angiocentric angiodestructive lymphomas
- Lymphomatoid granulomatosis
- Cutaneous plasmacytoma
- Pseudolymphomas
- Castleman disease
- Benign reactive lymphoid hyperplasia
- Cutaneous plasmacytosis
- Chapter 26. Metastatic tumors and simulators
- Breast carcinoma
- Carcinoma en cuirasse
- Inflammatory carcinoma (carcinoma erysipeloides)
- Alopecia neoplastica
- Lung carcinoma
- Small cell lung carcinoma
- Metastatic neuroendocrine carcinoma
- Renal carcinoma
- Colon carcinoma
- Ovarian carcinoma
- Signet-ring carcinoma
- Thyroid carcinoma
- Prostate carcinoma
- Metastatic malignant melanoma
- Metastatic squamous cell carcinoma
- Meningioma
- Lesions that mimic metastatic carcinoma
- Endometriosis
- Omphalomesenteric duct polyp
- Ectopic thymus
- Thymoma
- APPENDIX 1. Dermatopathology mnemonics
- APPENDIX 2. Skin ultrastructure
- 1 Desmosome
- 2 Langerhans cell (with Birbeck granules)
- 3 Premelanosome
- 4 Tonofibrils
- 5 Eosinophil
- 6 Mast cell
- 7 Merkel cell
- APPENDIX 3. External agents and artifacts
- Electrocautery
- Gelfoam
- Aluminum chloride
- Monsel’s solution (ferric subsulfate)
- Triamcinolone
- Splinter
- Suture
- Amalgam
- Calcium hydroxylapatite
- Hyaluronic acid
- Poly-l-lactic acid
- Polymethyl methacrylate
- Silicone granuloma
- Argyria
- Mercury granuloma
- Talon noir (black heel, calcaneal petechiae)
- Tattoo
- Tick parts
- Seabather’s eruption
- Factitial
- Index
- Edition: 4
- Published: November 18, 2024
- Imprint: Elsevier
- No. of pages: 612
- Language: English
- Hardback ISBN: 9780323930598
- eBook ISBN: 9780323931380
DE
Dirk M. Elston
Dirk M. Elston is Professor and Chair, Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina, Charleston, South Carolina, USA
Affiliations and expertise
Professor and Chair, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina, USATF
Tammie C. Ferringer
Affiliations and expertise
Section Head and Fellowship Director of Dermatopathology, Departments of Dermatology and Laboratory Medicine, Geisinger Medical Center, Danville, PA, USACK
Christine Ko
Christine Ko is Professor of Dermatology and Pathology at Yale Medical School, New Haven, CT, USA.
Affiliations and expertise
Professor of Dermatology and Pathology, Yale Medical School, New Haven, CT, USAWH
Whitney A. High
Whitney A. High is Associate Professor, Dermatology and Pathology, Director of Dermatopathology (Dermatology) at the University of Colorado School of Medicine, Aurora, Colorado.
Affiliations and expertise
Associate Professor, Dermatology and Pathology, Director of Dermatopathology (Dermatology), University of Colorado School of Medicine, Aurora, Colorado, USADD
David J. DiCaudo
David J. DiCaudo works in the Department of Dermatology, Mayo Clinic Arizona, Scottsdale, AZ, USA.
Affiliations and expertise
Department of Dermatology, Mayo Clinic Arizona, Scottsdale, AZ, USARead Dermatopathology on ScienceDirect