
Current research on naturally transmitted Plasmodium knowlesi
- 1st Edition, Volume 113 - September 28, 2021
- Imprint: Academic Press
- Editors: Russell Stothard, David Rollinson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 7 2 7 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 7 2 8 - 6
Plasmodium Knowlesi, Volume 113 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional a… Read more

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Request a sales quotePlasmodium Knowlesi, Volume 113 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Taking the strain out of onchocerciasis: a reanalysis of blindness and transmission data does not support the existence of a savanna blinding strain of onchocerciasis in West Africa, Enterocytozoon bieneusi of animals, Taenia solium taeniasis/cysticercosis, Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in eukaryotic pathogens, HTLV-I and Strongyloides: the worm lurking beneath, and more.
- Informs and updates on all the latest developments in the field of parasitology
- Includes medical studies of parasites of major influence
- Features reviews of more traditional areas, such as zoology, taxonomy and life history, which help shape current thinking and applications
PhD students, professors, scientists, health workers, government officers, and policy makers at various levels
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Plasmodium knowlesi, an infectious disease challenge for our times
- References
- Chapter One: Knowlesi malaria: Human risk factors, clinical spectrum, and pathophysiology
- Abstract
- 1: Introduction
- 2: Transmission in humans
- 3: Life cycle in humans
- 4: Human risk factors for symptomatic infection
- 5: Prepatent and incubation periods
- 6: Clinical spectrum in malariotherapy and experimental human infection
- 7: Clinical spectrum in natural infection
- 8: Genetic risk factors
- 9: Pathophysiology
- 10: Conclusion
- References
- Acknowledgements
- Chapter Two: Clinical management of Plasmodium knowlesi malaria
- Abstract
- 1: Introduction
- 2: Diagnosis of Plasmodium knowlesi
- 3: In vitro susceptibility of P. knowlesi to antimalarial agents
- 4: Drug resistance mutations
- 5: Treatment of uncomplicated knowlesi malaria
- 6: Clinical management of severe knowlesi malaria
- 7: Treatment of knowlesi malaria in children
- 8: Treatment of knowlesi malaria in pregnancy
- 9: Conclusions
- Acknowledgements
- References
- Chapter Three: Plasmodium knowlesi detection methods for human infections—Diagnosis and surveillance
- Abstract
- 1: Introduction
- 2: Point-of-care diagnosis
- 3: Molecular detection
- 4: Serology
- 5: Conclusion
- Acknowledgements
- References
- Chapter Four: The vectors of Plasmodium knowlesi and other simian malarias Southeast Asia: challenges in malaria elimination
- Abstract
- 1: Introduction
- 2: Simian malaria parasites in natural vector mosquitoes
- 3: Vectors of Plasmodium knowlesi—Leucosphyrus Group of Anopheles
- 4: Bionomics of natural vectors of Plasmodium kowlesi in the Leucosphyrus Group of Anopheles
- 5: Suspected vectors of knowlesi malaria in other Anopheles Groups
- 6: Experimental transmissions of Plasmodium knowlesi and other simian malaria parasites in mosquitoes
- 7: Control of vectors of P. knowlesi and other simian malarias
- 8: Challenges
- 9: Conclusions and the way forward
- Acknowledgement
- References
- Chapter Five: Molecular epidemiology and population genomics of Plasmodium knowlesi
- Abstract
- 1: Molecular detection in discovery of Plasmodium knowlesi as a significant zoonosis
- 2: Molecular surveys of the distribution of P. knowlesi infections in humans
- 3: Early utility of a few genetic loci for analysis of P. knowlesi polymorphism
- 4: Multi-locus microsatellite analyses of P. knowlesi uncovers population structure
- 5: Whole-genome sequence analysis of P. knowlesi subpopulation divergence
- 6: Loci under positive natural selection in the P. knowlesi genome
- 7: Assays for efficient surveillance of different P. knowlesi subpopulations
- 8: Adaptation and the future of P. knowlesi emerging from local zoonoses
- References
- Chapter Six: Epidemiology of the zoonotic malaria Plasmodium knowlesi in changing landscapes
- Abstract
- 1: Introduction
- 2: Ecological change and mechanisms of disease emergence and transmission
- 3: Distribution and burden of Plasmodium knowlesi
- 4: Landscape impacts on P. knowlesi disease dynamics
- 5: Transmission dynamics and potential for human to human transmission
- 6: Designing surveillance and control measures for changing environments
- 7: Conclusions and future research priorities
- References
- Edition: 1
- Volume: 113
- Published: September 28, 2021
- No. of pages (Hardback): 300
- No. of pages (eBook): 300
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780323907279
- eBook ISBN: 9780323907286
RS
Russell Stothard
Prof. Russell Stothard is Chair in Medical Parasitology at the Liverpool School of Tropical Medicine, UK
Affiliations and expertise
Chair in Medical Parasitology, Liverpool School of Tropical Medicine, UKDR
David Rollinson
Professor David Rollinson is a Merit Research Scientist at the Natural History Museum in London, where he leads a research team in the Wolfson Wellcome Biomedical Laboratories and directs the WHO Collaborating Centre for schistosomiasis. He has had a long fascination with parasites and the diseases that they cause, this has involved him in many overseas projects especially in Africa. He is on the WHO Expert Advisory Panel of parasitic diseases, the editor of Advances in Parasitology and a former President of the World Federation of Parasitologists. His research group uses a multidisciplinary approach, which combines detailed molecular studies in the laboratory with ongoing collaborative studies in endemic areas of disease, to explore the intriguing world of parasites in order to help control and eliminate parasitic diseases.
Affiliations and expertise
Merit Research Scientist, The Natural History Museum, London, UKRead Current research on naturally transmitted Plasmodium knowlesi on ScienceDirect