Critical Care Nephrology
- 3rd Edition - November 29, 2017
- Latest edition
- Authors: Claudio Ronco, Rinaldo Bellomo, John Kellum, Zaccaria Ricci
- Language: English
**Selected for Doody’s Core Titles® 2024 in Nephrology**Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of… Read more
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Description
Description
**Selected for Doody’s Core Titles® 2024 in Nephrology**
Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events.
Key features
Key features
- Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more
- Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool
- Presents information clearly, in a format designed for easy reference – from basic sciences to clinical syndromes to diagnostic tools
- Covers special populations such as children, diabetic patients, and the elderly
- An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians – anyone who treats critically ill renal patients
Table of contents
Table of contents
Section 1: Principles of Critical Care
1. The Critically Ill Patient
2. The Pathophysiologic Foundations of Critical Care
3. Mechanical Ventilation
4. Hemodynamic Support in the Critically Ill Patient
5. Monitoring Organ Dysfunction in Critical Care
6. Kidney-Specific Severity Scores
Section 2: Principles of Renal Physiology
7. The Physiology of the Glomerulus
8. The Physiology of the Loop of Henle
9. Glomerular Filtration Rate, Renal Functional Reserve, and Kidney Stress Testing
10. Renal Energy Consumption and Metabolism
Section 3: Epidemiology of Acute Kidney Injury in Critical Care
11. Acute Kidney Injury: From Clinical to Molecular Diagnosis
12. Community- and Hospital-Acquired Acute Kidney Injury
13. Epidemiology of Acute Kidney Injury in Critically Ill Patients
14. Acute Kidney Injury in Patients With Chronic Kidney Disease
Section 4: Exposures and Patient Susceptibility
15. Genetic Predisposition for Acute Kidney Injury (AKI)
16. Risk Factors and Risk Assessment in Acute Kidney Injury
17. Experimental Models of Acute Kidney Injury
Section 5: Humoral and Cellular Mechanisms of Kidney Damage
18. Renal Blood Flow and Perfusion Pressure
19. Humoral Mediators in Sepsis
20. Cell Death Pathways: Apoptosis and Regulated Necrosis
21. Pathogen-Associated Molecular Patterns, Damage-Associated Molecular Patterns, and Their Receptors in Acute Kidney Injury
Section 6: Clinical Course of Acute Kidney Injury and Biomarkers
22. Acute Kidney Disease
23. Acute Kidney Disease, Renal Recovery, and Post–Acute Kidney Injury Care
24. The Role of Biomarkers in the Diagnosis and Management of Acute Kidney Injury
25. Functional Biomarkers
26. Damage Biomarkers
27. Kidney Stress Biomarkers
Section 7: Mechanisms of Repair or Progression
28. Renal Repair and Recovery
29. Maladaptive Repair and Progression to CKD
30. Biomarkers of Recovery and/or Repair Following Acute Kidney Injury
Section 8: Renal Histopathology in Acute Kidney Injury
31. Practical Considerations of Renal Biopsies in Critical Care Patients
32. Localization of Injury and Repair Pathways
Section 9: Imaging Techniques in Critical Care Nephrology
33. Ultrasonography and Doppler Techniques
34. Contrast-Enhanced Renal Ultrasound
35. Traditional Radiology, Computed Tomography, and Magnetic Resonance Imaging in Critical Care Nephrology
36. Radionuclides Diagnostic Techniques
Section 10: Clinical Syndromes and Acute Kidney Injury
37. Multiple Organ Dysfunction
38. Acute Kidney Injury in Burns and Trauma
39. Drug-Induced Acute Kidney Injury
40. Acute Kidney Injury in Pregnancy
41. Acute Kidney Injury in Oncology and Tumor Lysis Syndrome
42. Acute Kidney Injury in Cardiac Surgery
43. Acute Kidney Injury in Major Surgery
44. Acute Kidney Injury in Heart Failure
45. Acute Kidney Injury in Cirrhosis
46. Acute Renal Failure in Kidney Transplant Recipients
47. Acute Glomerulonephritis
48. Contrast-Induced Acute Kidney Injury
49. Abdominal Compartment Syndrome
50. Hemolytic Uremic Syndrome
Section 11: Prevention and Treatment: General Treatment Concepts
51. Nonpharmacologic Management of Acute Renal Injury
52. Novel Drugs for Acute Kidney Injury
53. Remote Ischemic Preconditioning
Section 12: Fluid and Electrolytes
54. Blood Biochemistry: Measuring Major Plasma Electrolytes
55. Assessment of Urine Biochemistry
56. Disorders of Sodium and Water Balance
57. Disorders of Potassium and Magnesium
58. Calcium and Phosphate Physiology
59. Principles of Fluid Therapy
60. Blood Transfusion Therapy
61. Loop and Thiazide Diuretics
62. Vaptans and the Treatment of Hyponatremia
63. Aldosterone Antagonists, Amiloride, and Triamterene
Section 13: Acid-Base
64. Laboratory Tests: Blood Gases, Anion Gap, and Strong Ion Gap
65. Acid-Base Physiology and Diagnosis of Disorders
66. Metabolic Acidosis
67. Hyperlactatemia and Lactic Acidosis
68. Renal Tubular Acidosis
69. Metabolic Alkalosis
70. Respiratory Acid-Base Disorders
71. Iatrogenic and Poison-Derived Acid Base Disorders
Section 14: Metabolism and Nutrition in Critical Illness and Acute Kidney Injury
72. Energy Requirement and Consumption in the Critically Ill Patient
73. Impact of Renal Replacement Therapy on Metabolism and Nutrient Requirements in the Critically Ill Patient
74. Amino Acid Turnover, Protein Metabolism, and Nitrogen Balance in Acute Kidney Injury
75. Carbohydrates and Lipids
76. Endocrinology of the Stress Response During Critical Illness
77. Anemia of Critical Illness
78. Management of Nutrition in Acute Kidney Injury and Renal Replacement Therapy
79. Blood Glucose Control in Critical Care
80. Enteral Nutrition
Section 15: Infectious Diseases and Sepsis
81. Microbiologic Considerations in the Intensive Care Patient
82. Innate Immunity and the Kidney
83. Adaptive Immunity and Critical Illness
84. Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome
85. Tropical Infections Causing Acute Kidney Injury
86. Sepsis and Septic Shock
87. Complement and Its Consequences in Sepsis
88. Coagulation Abnormalities in Sepsis
Dysfunction of the Kidney in Sepsis
Book chapterFull text access
89. Endothelial Dysfunction of the Kidney in Sepsis
90. Sepsis-Induced Acute Kidney Injury
91. Recommendations for Sepsis Management
92. Principles of Antimicrobial Prescription in Intensive Care Unit Patients With Acute Kidney Injury
93. Renal Replacement Therapy for Septic Acute Kidney Injury
94. Blood Purification for Sepsis
95. Management of Infection in Patients With Kidney Transplant
96. Critical Care Viral Infections
97. Principles of Antibiotic Prescription in Intensive Care Unit Patients and Patients With Acute Renal Failure
Section 16: Acute Intoxication and Poisoning
98. Drugs and Antidotes in Acute Intoxication
99. Extracorporeal Therapies in Acute Intoxication and Poisoning
100. Plasmapheresis in Acute Intoxication and Poisoning
101. Poisoning: Kinetics to Therapeutics
Section 17: Acute Kidney Injury and Organ Crosstalk
102. Bleeding and Hemostasis in Acute Renal Failure
103. Gastrointestinal Problems in Acute Kidney Injury
104. Cardiovascular Problems in Acute Kidney Injury
105. Water and Electrolyte Disturbances in Acute Renal Failure
106. Neurologic Problems in Acute Renal Failure
107. Immunologic and Infectious Complications of Acute Kidney Injury
108. Cellular Response to Acute Kidney Injury
Section 18: Interaction of the Heart and the Kidney
109. Heart-Kidney Cross-Talk
110. Classification of Cardiorenal Syndrome
111. Cardiorenal Syndrome Type 1
112. Cardiorenal Syndrome Type 2
113. Cardiorenal Syndrome Type 3
114. Cardiorenal Syndrome Type 4
115. Cardiorenal Syndrome Type 5
116. Renal Function During Cardiac Mechanical Support and Artificial Heart
117. The Kidney in Diastolic Dysfunction
118. Principles of Diuretic Management in Heart Failure
119. Management of Overhydration in Heart Failure Patients
120. Recent Advances for Stroke Prevention in Patients With Atrial Fibrillation and Advanced Kidney Disease
Section 19: Interaction of the Lung and Kidney
121. Lung-Kidney Cross-Talk
122. The Kidney During Mechanical Ventilation
123. Extracorporeal Membrane Oxygenation and Renal Function
124. Extracorporeal Carbon Dioxide Removal
125. Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy in Adults and Children
126. Pulmonary-Renal Syndrome
Section 20: The Liver and the Kidney
127. Liver-Kidney Interaction
128. Pathophysiology and Management of the Hepatorenal Syndrome
129. Kidney Dysfunction After Liver Transplantation
130. Extracorporeal Liver Support Devices
Section 21: Interaction of the Brain and the Kidney
131. Treatment of Combined Acute Renal Failure and Cerebral Edema
132. Renal Protection in the Organ Donor
133. Effect of Extracorporeal Therapies on the Brain
Section 22: Fluid Balance and its Management in the Critically Ill
134. Components of Fluid Balance and Monitoring
135. Noninvasive Methods of Fluid Status Assessment in Critically Ill Patients
136. Management of Fluid Overload in Cardiorenal Patients: The Five B Approach
137. Mechanical Fluid Removal
Section 23: General Principles of Acute Renal Replacement Therapy
138. Indications for Renal Replacement Therapy in the Critically Ill
139. Principles of Extracorporeal Circulation and Transport Phenomena
140. Membranes and Filters for Use in Acute Renal Failure
141. Continuous Renal Replacement Therapy Machine Technology
142. Principles of Anticoagulation in Extracorporeal Circuits
143. Dialysis Solutions and Replacement Fluids
144. Starting and Stopping Renal Replacement Therapy in the Critically Ill
145. The Concept of Renal Replacement Therapy Dose and Efficiency
146. Quantification of Acute Renal Replacement Therapy
147. Principles of Pharmacodynamics and Pharmacokinetics of Drugs Used in Extracorporeal Therapies
148. Ethical Considerations in Acute Renal Replacement Therapy
Section 24: Intermittent Renal Replacement Therapies
149. Intermittent Techniques for Acute Dialysis
150. Solute and Water Transport in Hemodialysis: Dialyzers, Flow Distribution, and Cross-Filtration
151. Biocompatibility of the Dialysis System
152. Composition of Hemodialysis Fluid
153. Indications for and Contraindications to Intermittent Hemodialysis in Critically Ill Patients
154. Technical and Clinical Complications of Intermittent Hemodialysis in the Intensive Care Unit
155. Correction of Water, Electrolyte, and Acid-Base Derangements by Hemodialysis and Derived Techniques
156. Urea Kinetics, Efficiency, and Adequacy of Hemodialysis and Other Intermittent Treatments
157. Assessment of Fluid Status and Body Composition and Control of Fluid Balance With Intermittent Hemodialysis in the Critically Ill Patient
158. Outcomes of Intermittent Hemodialysis in Critically Ill Patients With Acute Kidney Injury
159. Hybrid Dialysis Techniques in the Intensive Care Unit
160. The Role of Plasmapheresis in Critical Illness
161. Cascade Filtration for ABO Incompatible Transplant
162. Nursing Issues and Procedures in Continuous Renal Replacement Therapy
Section 25: Continuous Renal Replacement Therapies (CRRT)
163. Indications for Continuous Renal Replacement Therapy: Renal Replacement Versus Renal Support
164. Beginning and Ending Continuous Renal Replacement Therapy in the Intensive Care Unit
165. Solute and Water Kinetics in Continuous Therapies
166. Continuous Renal Replacement Therapy: Modalities and Their Selection
167. Vascular Access for Acute Renal Replacement Therapy
168. Anticoagulation Strategies for Continuous Renal Replacement Therapy
169. Nursing Strategies to Prevent Coagulation of the Extracorporeal Circuit
170. Adequacy of Continuous Renal Replacement Therapy: Prescription and Delivery
171. High-Volume Hemofiltration in the Intensive Care Unit
172. Pulse High-Volume Hemofiltration in Management of Critically Ill Patients With Severe Sepsis or Septic Shock
173. High Cutoff Membranes for Mediators Removal
174. Clinical Effects of Continuous Renal Replacement Therapies
175. Antibiotic Adjustment in Continuous Renal Replacement Therapy
176. Nomenclature: Basic Principles
177. Nomenclature: Techniques
Section 26: Peritoneal Dialysis in the Intensive Care Unit
178. Peritoneal Dialysis System
179. Indications, Contraindications, and Complications of Peritoneal Dialysis in Acute Renal Failure
180. Solute and Water Transport Across the Peritoneal Barrier
181. Choice of Peritoneal Dialysis Technique: Intermittent or Continuous
182. Correction of Fluid, Electrolyte, and Acid-Base Derangements by Peritoneal Dialysis in Acute Kidney Injury
183. Feasibility, Efficiency, and Adequacy of Peritoneal Dialysis in Acute Kidney Injury
184. Clinical Results and Complications of Peritoneal Dialysis in Acute Kidney Injury
185. Treatment of Peritonitis and Other Clinical Complications of Peritoneal Dialysis in the Critically Ill Patient
186. Comparison of Peritoneal Dialysis With Other Treatments for Acute Kidney Injury
187. Continuous-Flow Peritoneal Dialysis as Acute Therapy
188. Nursing and Procedure Issues in Peritoneal Dialysis
Section 27: Extracorporeal Blood Purification Techniques Beyond Dialysis
189. Sorbents: From Basic Structure to Clinical Application
190. Therapeutic Apheresis in Critically Ill Patients: Indications, Modalities and Techniques, Clinical Results
191. Extracorporeal Blood Purification Techniques Beyond Dialysis: Coupled Plasmafiltration-Adsorption
192. Prometheus System
193. Toraymyxin and Other Endotoxin Adsorption Systems
194. Plasmafiltration-Adsorption-Dialysis System
195. Extracorporeal Membrane Oxygenation for Cardiac Support
196. Extracorporeal Membrane Oxygenation for Pulmonary Support
197. Cell-Based Therapies
Section 28: Critical Care Nephrology in Pediatrics
198. Cellular and Molecular Mechanisms of Acute Kidney Injury
199. Epidemiology of Pediatric Acute Kidney Injury
200. Treatment of Acute Kidney Injury in Children: Conservative Management to Renal Replacement Therapy
201. Technical Aspects of Pediatric Continuous Renal Replacement Therapy
202. Multiple Organ Dysfunction in the Pediatric Intensive Care Unit
203. Drug Dosing in Pediatric Acute Kidney Insufficiency and Renal Replacement Therapy
204. Nutrition of Critically Ill Children With Acute Renal Failure
205. Outcome of Pediatric Acute Kidney Injury
206. Renal Replacement Therapy for the Critically Ill Infant
207. Neonatal Hyperammonemia and Continuous Renal Replacement Therapy
208. Modified Ultrafiltration in Pediatric Heart Surgery
209. Techniques and Machines for Pediatric Renal Replacement Therapy
210. Antibiotics in Critically Ill Newborns and Children: Nephrotoxicity and Management During Renal Replacement Therapy
Section 29: Kidney Transplantation and Critical Care
211. Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
212. Kidney Support and Perioperative Care in Kidney Transplantation
213. Acute Renal Failure in Kidney Transplant Recipients
Section 30: Special Kidney Problems in the Intensive Care Unit
214. Management of Chronic Kidney Disease and End-Stage Kidney Disease Patients in the Intensive Care Unit
215. Management of Patients with Diabetes in the Intensive Care Unit
216. Diagnosis and Management of Acute Kidney Injury in the Emergency Department
217. Anticancer Drugs and the Kidney
218. Antiinflammatory Drugs and the Kidney
219. Calcineurin Inhibitors and Other Immunosuppressive Drugs and the Kidney
220. Alternative Medicine and Chinese Herbs and the Kidney
221. Environment, Smoking, Obesity, and the Kidney
222. Lead and Heavy Metals and the Kidney
223. Statins and the Kidney
224. Erythropoietin Therapy in Critically Ill and Acute Kidney Injury Patients
225. Vasoactive Drugs, Renal Function, and Acute Kidney Injury
226. End Points for Clinical Trials in Acute Kidney Injury
227. Hypothermia and the Kidney
228. Renin-Angiotensin System Blockers and Acute Kidney Injury
Review quotes
Review quotes
"This is an excellent source of in-depth information on the intersection between critical illness and nephrology, making it a useful resource for practicing nephrologists or trainees about to enter practice given today's increasing acuity and use of the ICU. The comprehensive review of evidence is well cited, with many chapters written by recognizable field leaders, and well organized into intuitive sections. While it is a large book, its many chapters help compartmentalize information and it would work well as a quick reference guide once readers are familiar with its content. The electronic version is a nice addition and helps readers quickly search its content, but is not required. Overall, this book is an extensive and accessible review of current intensive care nephrology and would serve as an excellent resource for clinicians looking to expand their knowledge on an increasingly common intersection of practice." -Reviewed by Paul Adams, BS MD (University of Kentucky College of Medicine) Doody's Score: 93, 4 Stars!
Product details
Product details
- Edition: 3
- Latest edition
- Published: December 6, 2017
- Language: English
About the authors
About the authors
CR
Claudio Ronco
RB
Rinaldo Bellomo
JK
John Kellum
Dr. Kellum is a Distinguished Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science and holds an Endowed Chair in Critical Care Research from the University of Pittsburgh. He is currently on leave and serving as the Chief Medical Officer for Spectral Medical, a late-stage medical device company developing diagnostics and therapeutics for sepsis. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh. His research interests span various aspects of Critical Care Medicine but center in critical care nephrology, sepsis, and multi-organ failure. He has authored more than 750 publications, has won several teaching awards teaching, has given more than 500 seminars and invited lectures worldwide.
ZR