Control Mechanisms in Developmental Processes

Contributors and Presiding Chairmen

Foreword

History of the Symposium Volumes

I. The Role of Cytoplasmic Units

Control Mechanisms in Plastid Development

Introduction

The Control of Plastid Development by the Nuclear Genome

Proplastid to Chloroplast

Summary Discussion

Chairman's Comments—June Lascelles

References

Nuclear and Cytoplasmic Control of Morphology in Neurospora

Comparison of Biochemical and Morphological Mutants

Nuclear Control of Morphology

Extranuclear Control of Morphology

Involvement of Mitochondria

Possible Involvement of Mitochondrial DNA

Cytology of Abnormal Cultures

Biology of Conversion

Cytochrome Pattern in Conversion

Conclusions

References

Developmental and Control Processes in the Basal Bodies and Flagella of Chlamydomonas reinhardii

Introduction

The Development and Regression of Flagella and Basal Bodies in Chlamydomonas reinhardii

The Genetic Control of Flagella Structure in Chlamydomonas reinhardii

Macromolecular Basis of Morphopoiesis and Structure in Flagella

Regeneration of Chlamydomonas Flagella: Some Experimental and Theoretical Considerations

General Discussion

References

II. The Role of the Nucleus

Genetic Systems Regulating Gene Expression during Development

Introduction

Illustrations of the Mode of Operation of a Regulatory System in Maize

Evidence of Controlling Elements in Organisms Other Than Maize

References

Gene Action, Mitotic Frequency, and Morphogenesis in Higher Plants

Introduction

Relationships between Cell Enlargements and Cell Division

Effects of Genes Acting at Different Stages of Development

Developmental Features of Corngrass in Maize

The Hooded Gene in Barley

Relationship between Mitotic Frequency and Orientation of Mitoses

Discussion and Summary

References

Regulation of the Cell Cycle in Mammalian Cells: Inferences and Speculations Based on Observations of Interspecific Somatic Hybrids

Prefatory Note

Introduction

Properties of Rat ×Mouse and Hamster ×Mouse Hybrids

Inferences concerning the Coordination of the Events of the Cell Cycle

Appendix I: Summary of Work on Hybridization of Somatic Cells

Appendix II: Notes

References

Masked Messenger RNA and Cytoplasmic DNA in Relation to Protein Synthesis and Processes of Fertilization and Determination in Embryonic Development

Introduction

Messenger RNA

Stimulation of Protein Synthesis upon Fertilization

Evidence for Masked Messenger RNA (mmRNA)

Extent and Duration of Action of mmRNA

mmRNA Synthesis during Early Development

Polysome Formation upon Fertilization

Protein Synthesis in Unfertilized Eggs

Location of mmRNA in Unfertilized Eggs and in Developing Embryos

Relation of Histones to mRNA Synthesis

mmRNA Synthesis and Embryonic Determination

Cytoplasmic DNA

Summary

Chairman's Comments—Arthur Η. Whiteley

References

III. Regulatory Mechanisms

Erythroid Cell Differentiation and the Synthesis and Assembly of Hemoglobin

Introduction

Erythroid Cell Differentiation and the Induction of Hemoglobin Synthesis

Regulation of Heme Biosynthesis

Regulation of Globin Synthesis by Heme

The Role of Heme in the Assembly of Hemoglobin

References

The Development of Immunocompetent Cells

Introduction

Tissue Interaction during Lymphoid Morphogenesis

The Thymus as a Source of Immunocompetent Cells

Bone Marrow as a Source of Immunocompetent Cells

Embryonic Liver as a Source of Immunocompetent Cells

Yolk Sac Origin of Immunocompetent Cells

Concluding Remarks

Addendum

References

Regulatory Action of Estrogenic Hormones

Introduction

The Effect of Estrogen on RNA Synthesis

The Effect of Metabolic Inhibitors

The Biological Activity of Uterine RNA

Morphological Effects

Enzymatic Effects

Physiological Effects

Estrogen Binding and RNA Synthesis

References

Author Index

Subject Index