
Comprehensive Clinical Nephrology
Text with CD-ROM
- 2nd Edition - July 23, 2003
- Imprint: Mosby Ltd.
- Author: Richard J. Johnson
- Language: English
The second edition of Comprehensive Clinical Nephrology will build on the strengths of the first edition to bring the reader the most up-to-date information on every clinical cond… Read more

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The second edition of Comprehensive Clinical Nephrology will build on the strengths of the first edition to bring the reader the most up-to-date information on every clinical condition encountered in nephrology in one concise but comprehensive, clinically focussed volume.
Every chapter has been fully revised and updated, with new chapters on renal disease in the elderly, management of renal diseases in septic shock or the ICU setting, and urologic conditions of relevance to the nephrologist. There is much greater coverage of the surgical management of renal stone disease, the management of renal disease in the ICU, acute pancreatitis and Leptospirosis as causes of acute renal failure, renal, bladder and prostate malignancy, and much more.
Clinically focussed and highly illustrated in full colour throughout, Comprehensive Clinical Nephrology is an invaluable bedside resource for the trainee or practicing clinician in nephrology, internal medicine or critical care.
Every chapter has been fully revised and updated, with new chapters on renal disease in the elderly, management of renal diseases in septic shock or the ICU setting, and urologic conditions of relevance to the nephrologist. There is much greater coverage of the surgical management of renal stone disease, the management of renal disease in the ICU, acute pancreatitis and Leptospirosis as causes of acute renal failure, renal, bladder and prostate malignancy, and much more.
Clinically focussed and highly illustrated in full colour throughout, Comprehensive Clinical Nephrology is an invaluable bedside resource for the trainee or practicing clinician in nephrology, internal medicine or critical care.
- Gives the best clinical advice available form the worlds leading experts
- Give the reader both the principles and practice of clinical medicine for every disorders
- Assists in the decision as to which tests to order
- Reader is able to locate material more easily due to standard layout of each chapter
- Ensures the best possible coverage of the specialty form the experts worldwide
- Relevant but not exhaustive references of key papers makes it easy to locate essential references
- Makes the complex acid-base principles easy to understand and helps put them in the clinical context of the disease process
MARKET
Residents / trainees in nephrology, consultant / attending / practicing nephrologists. Also specialists in hypertension, general internal medicine, diabetes, urology and critical care.
There are approx. 5,500 board certified nephrologists and approx. 800 residents in the USA. The American Society of Nephrology has approx. 6,500 members. There are 300 consultant nephrologists in the UK, and approx. 2,600 in Europe.
Residents / trainees in nephrology, consultant / attending / practicing nephrologists. Also specialists in hypertension, general internal medicine, diabetes, urology and critical care.
There are approx. 5,500 board certified nephrologists and approx. 800 residents in the USA. The American Society of Nephrology has approx. 6,500 members. There are 300 consultant nephrologists in the UK, and approx. 2,600 in Europe.
Section 1: ESSENTIAL RENAL ANATOMY AND PHYSIOLOGY
1. Renal Anatomy
2. Renal Physiology
Section 2: INVESTIGATION OF RENAL DISEASE
3. Assessment of Renal Function
4. Urinalysis
5. Imaging
6. Renal Biopsy
Section 3: FLUID AND ELECTROLYTE DISORDERS
7. Disorders of Extracellular Volume
8. Disorders of Water Metabolism
9. Disorders of Potassium Metabolism
10. Disorders of Calcium, Phosphate, and Magnesium Metabolism
11. Normal Acid-Base Balance and Metabolic Acidosis
12. Metabolic Alkalosis
13. Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders
Section 4: ACUTE RENAL FAILURE
14. Clinical Evaluation, Management, and Outcome of Acute Renal Failure
15. Causes of Acute renal Failure
16. Hepatorenal Syndrome
17. Myeloma Kidney
Section5: GLOMERULAR DISEASE
18. Introduction to Glomerular Disease: Pathogenesis and Classification
19. Introduction to Glomerular Disease: Clinical Presentations
20. Minimal Change Disease and Primary Focal Segmental Glomerulosclerosis
21. Secondary Focal Segmental Glomerulosiclerosis
22. Membranous Nephropathy
23. Membranoproliferative Glomerulonephritis and Cryoglobulinemic Glomerulonephritis
24. IgA Nephropathy and Henoch-Schonlein Nephritis
25. Antiglomerular Basement Membrane Disease and Goodpasture’s Syndrome
26. Renal and Systemic Vasculitis
27. Lupus Nephritis
28. Glomerular Disease Associated with Infection
29. Renal Amyloidosis and Glomerular Diseases with Monoclonal Immunoglobulin Deposition
30. Other Glomerular Disorders
31. Thrombotic Microangiopathies including Hemolytic Uremic Syndrome
Section 6: DIABETIC NEPHROPATHY
32. Clinical Manifestations and Natural History of Diabetic Nephropathy
33. Pathogenesis, Prevention, and Treatment of Diabetic Nephropathy
34. Management of End-stage Renal Disease in Diabetes
Section 7: HYPERTENSION
35. Normal Blood Pressure Control and the Evaluation of Hypertension
36. Pathogenesis and Clinical Course of Essential Hypertension
37. Nonpharmacologic Treatment of Hypertension
38. Pharmacologic Treatment of Hypertension
39. Renovascular Hypertension
40. Endocrine Causes of Hypertension
41. Neurogenic Hypertension Including Following Stroke and with Spinal Cord Injury
42. Hypertension in African-Americans
Section 8: PREGNANCY AND RENAL DISEASE
43. Renal Physiology in Normal Pregnancy
44. Renal Complications in the Normal Pregnancy
45. Pregnancy with Pre-Existing Renal Disease
Section 9: HEREDITARY AND CONGENTIAL DISEASES OF THE KIDNEY
46. Autosomal Dominant Polycystic Kidney Disease
47. Other Cystic Kidney Diseases
48. Alport and Other Familial Glomerular Syndromes
49. Inherited Disorders of Sodium and Water Handling
50. Fanconi's Syndrome and Other Proximal Tubule Disorders
51. Sickle Cell Disease
52. Congenital Abnormalities of the Renal Tract
Section 10: URINARY TRACT INFECTION
53. Urinary Tract Infections in Adults
54. Tuberculosis of the Urinary Tract
55. Fungal Infection of the Urinary Tract
56. Urinary Schistosomiasis
Section 11: UROLOGICAL DISORDERS
57. Nephrolithiasis and Nephrocalcinosis
58. Urinary Tract Obstruction
59. Urological Issues for the Nephrologist
Section 12: TUBULOINTERSTITIAL DISEASE
60. Acute Interstitial Nephritis
61. Vesicoureteral Reflux and Reflux Nephropathy
62. Chronic Interstitial Nephritis
Section 13: VASCULAR DISEASE
63. Atheromatous Renovascular Disease
64. Renal Vascular Thrombosis and Occlusion
65. Aging and the Kidney
Section 14: CHRONIC RENAL FAILURE AND THE UREMIC SYNDROME
66. Progression of Chronic Renal Failure
67. Clinical Evaluation and Manifestations of Chronic Renal Failure
68. Bone and Mineral Metabolism in Chronic Renal Failure
69. Cardiovascular Disease in Chronic Renal Failure
70. Anemia in Chronic Renal Failure
71. Platelet Dysfunction and Coagulation Defects
72. ß2-Microglobulin-derived Amyloid
73. Acquired Cystic Kidney Disease
74. Nutrition in Chronic Renal Failure
Section 15: DIALYSIS
75. Selection and Preparation of Patients for Dialysis
76. Vascular Access for Hemodialysis
77. Interventional Nephrology
78. Hemodialysis: Mechanisms, Outcome, and Adequacy
79. Acute Complications of Hemodialysis
80. Peritoneal Dialysis: Principles, Techniques and Adequacy
81. Complications of Peritoneal Dialysis
82. Other Dialysis Modalities
83. Plasma Exchange
Section 16: TRANSPLANTATION
84. Immunologic Principles of Transplantation
85. Immunosuppressive Agents used in Transplantation
86. Evaluation of Renal Transplant Donor and Recipient
87. Renal Transplant Surgery
88. Prophylaxis and Treatment of Renal Transplant Rejection
89. The Medical Management of the Renal Transplant Recipient
90. Chronic Transplant Rejection
91. Recurrent Disease in the Renal Transplant
92. Outcomes in Renal Transplantation
93. Pancreas and Islet Transplantation
94. Renal Disease in Liver, Cardiac, Bone Marrow Transplantation
Section 17: DRUGS AND THE KIDNEY
95. Poisoning and Drug Overdose
96. Principles of Drug Dosing and Prescribing in Renal Failure
1. Renal Anatomy
2. Renal Physiology
Section 2: INVESTIGATION OF RENAL DISEASE
3. Assessment of Renal Function
4. Urinalysis
5. Imaging
6. Renal Biopsy
Section 3: FLUID AND ELECTROLYTE DISORDERS
7. Disorders of Extracellular Volume
8. Disorders of Water Metabolism
9. Disorders of Potassium Metabolism
10. Disorders of Calcium, Phosphate, and Magnesium Metabolism
11. Normal Acid-Base Balance and Metabolic Acidosis
12. Metabolic Alkalosis
13. Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders
Section 4: ACUTE RENAL FAILURE
14. Clinical Evaluation, Management, and Outcome of Acute Renal Failure
15. Causes of Acute renal Failure
16. Hepatorenal Syndrome
17. Myeloma Kidney
Section5: GLOMERULAR DISEASE
18. Introduction to Glomerular Disease: Pathogenesis and Classification
19. Introduction to Glomerular Disease: Clinical Presentations
20. Minimal Change Disease and Primary Focal Segmental Glomerulosclerosis
21. Secondary Focal Segmental Glomerulosiclerosis
22. Membranous Nephropathy
23. Membranoproliferative Glomerulonephritis and Cryoglobulinemic Glomerulonephritis
24. IgA Nephropathy and Henoch-Schonlein Nephritis
25. Antiglomerular Basement Membrane Disease and Goodpasture’s Syndrome
26. Renal and Systemic Vasculitis
27. Lupus Nephritis
28. Glomerular Disease Associated with Infection
29. Renal Amyloidosis and Glomerular Diseases with Monoclonal Immunoglobulin Deposition
30. Other Glomerular Disorders
31. Thrombotic Microangiopathies including Hemolytic Uremic Syndrome
Section 6: DIABETIC NEPHROPATHY
32. Clinical Manifestations and Natural History of Diabetic Nephropathy
33. Pathogenesis, Prevention, and Treatment of Diabetic Nephropathy
34. Management of End-stage Renal Disease in Diabetes
Section 7: HYPERTENSION
35. Normal Blood Pressure Control and the Evaluation of Hypertension
36. Pathogenesis and Clinical Course of Essential Hypertension
37. Nonpharmacologic Treatment of Hypertension
38. Pharmacologic Treatment of Hypertension
39. Renovascular Hypertension
40. Endocrine Causes of Hypertension
41. Neurogenic Hypertension Including Following Stroke and with Spinal Cord Injury
42. Hypertension in African-Americans
Section 8: PREGNANCY AND RENAL DISEASE
43. Renal Physiology in Normal Pregnancy
44. Renal Complications in the Normal Pregnancy
45. Pregnancy with Pre-Existing Renal Disease
Section 9: HEREDITARY AND CONGENTIAL DISEASES OF THE KIDNEY
46. Autosomal Dominant Polycystic Kidney Disease
47. Other Cystic Kidney Diseases
48. Alport and Other Familial Glomerular Syndromes
49. Inherited Disorders of Sodium and Water Handling
50. Fanconi's Syndrome and Other Proximal Tubule Disorders
51. Sickle Cell Disease
52. Congenital Abnormalities of the Renal Tract
Section 10: URINARY TRACT INFECTION
53. Urinary Tract Infections in Adults
54. Tuberculosis of the Urinary Tract
55. Fungal Infection of the Urinary Tract
56. Urinary Schistosomiasis
Section 11: UROLOGICAL DISORDERS
57. Nephrolithiasis and Nephrocalcinosis
58. Urinary Tract Obstruction
59. Urological Issues for the Nephrologist
Section 12: TUBULOINTERSTITIAL DISEASE
60. Acute Interstitial Nephritis
61. Vesicoureteral Reflux and Reflux Nephropathy
62. Chronic Interstitial Nephritis
Section 13: VASCULAR DISEASE
63. Atheromatous Renovascular Disease
64. Renal Vascular Thrombosis and Occlusion
65. Aging and the Kidney
Section 14: CHRONIC RENAL FAILURE AND THE UREMIC SYNDROME
66. Progression of Chronic Renal Failure
67. Clinical Evaluation and Manifestations of Chronic Renal Failure
68. Bone and Mineral Metabolism in Chronic Renal Failure
69. Cardiovascular Disease in Chronic Renal Failure
70. Anemia in Chronic Renal Failure
71. Platelet Dysfunction and Coagulation Defects
72. ß2-Microglobulin-derived Amyloid
73. Acquired Cystic Kidney Disease
74. Nutrition in Chronic Renal Failure
Section 15: DIALYSIS
75. Selection and Preparation of Patients for Dialysis
76. Vascular Access for Hemodialysis
77. Interventional Nephrology
78. Hemodialysis: Mechanisms, Outcome, and Adequacy
79. Acute Complications of Hemodialysis
80. Peritoneal Dialysis: Principles, Techniques and Adequacy
81. Complications of Peritoneal Dialysis
82. Other Dialysis Modalities
83. Plasma Exchange
Section 16: TRANSPLANTATION
84. Immunologic Principles of Transplantation
85. Immunosuppressive Agents used in Transplantation
86. Evaluation of Renal Transplant Donor and Recipient
87. Renal Transplant Surgery
88. Prophylaxis and Treatment of Renal Transplant Rejection
89. The Medical Management of the Renal Transplant Recipient
90. Chronic Transplant Rejection
91. Recurrent Disease in the Renal Transplant
92. Outcomes in Renal Transplantation
93. Pancreas and Islet Transplantation
94. Renal Disease in Liver, Cardiac, Bone Marrow Transplantation
Section 17: DRUGS AND THE KIDNEY
95. Poisoning and Drug Overdose
96. Principles of Drug Dosing and Prescribing in Renal Failure
- Edition: 2
- Published: July 23, 2003
- Imprint: Mosby Ltd.
- Language: English
RJ
Richard J. Johnson
Affiliations and expertise
Professor of Medicine, Division Chief, Tomas Berl Professor of Nephrology, University of Colorado–Denver, Denver, Colorado, USA