
Coffee in Health and Disease Prevention
- 2nd Edition - September 14, 2024
- Imprint: Academic Press
- Editors: Victor R Preedy, Vinood Patel
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 8 6 8 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 8 6 9 - 0
Coffee in Health and Disease Prevention, Second Edition, presents a comprehensive look at the compounds in coffee, their benefits (or adverse effects), and explores coffee as it… Read more

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Request a sales quoteCoffee in Health and Disease Prevention, Second Edition, presents a comprehensive look at the compounds in coffee, their benefits (or adverse effects), and explores coffee as it relates to specific health conditions. Embracing a holistic approach, this book covers the coffee plant, coffee production and processing, the major varieties of coffee, and its nutritional and compositional properties. Coffee’s impact on human health, disease risk, and prevention comprises the majority of the text. Diseases covered including Alzheimer’s, anxiety and depression, asthma, diabetes, cancer, and more. This book also covers coffee’s impact on organs and organ systems, including the cardiovascular system, the nervous system, and the gut microbiome.
Coffee in Health and Disease Prevention, Second Edition, is the only book on the market that covers all varieties of coffee in one volume and their potential benefits and risks to human health. This is an essential reference for researchers in nutrition, dietetics, food science, biochemistry, and public health.
Coffee in Health and Disease Prevention, Second Edition, is the only book on the market that covers all varieties of coffee in one volume and their potential benefits and risks to human health. This is an essential reference for researchers in nutrition, dietetics, food science, biochemistry, and public health.
- Presents a comprehensive, translational source on the role of coffee in disease prevention and health
- Focuses on coffee’s nutritional and protective aspects, as well as specific coffee components and their effects on tissue and organ systems
- Offers a “one stop shop” for research in this area, compiling both foundational and cutting-edge topics into one resource
- Includes a dictionary of key terms, other health effects of coffee or extracts, and a summary points section within each chapter for a quick reference
Researchers interested in food science (particularly those with an interest in coffee), nutrition, and disease prevention Dieticians, nutritionists, and clinicians
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- Preface
- Section I. Coffee, coffee drinking, and varieties
- Chapter 1. An introduction to the coffee plant and seeds
- Introduction
- The plant
- Green coffee production
- Summary points
- Chapter 2. Coffea arabica
- Introduction
- Origin and distribution
- Botanical description
- Production
- Industrial processing
- Bioactive compounds
- Theophylline
- Theobromine
- Cafestol and kahweol
- Antioxidants
- Health benefits
- Physical performance
- Heart health
- Diabetes
- Antiinflammatory properties
- Mental illness
- Coffee products
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 3. Coffea canephora (robusta): Quality and health benefits
- Introduction
- Origin and distribution
- Resistance and cultivation
- Flavor and aroma
- Bioactive compounds content
- Genetic composition
- Commercial products
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 4. Green coffee
- Introduction
- Phytochemical components of green coffee
- Research on green coffee
- Pharmacological activities
- Toxicity studies
- Mini-dictionary of terms
- Summary points
- Chapter 5. Evolution and organization of Coffea genomes
- Introduction
- Genome structure and divergence
- Genomic diversity based on transposable elements
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 6. Genomics to reveal divergence and convergence between coffee species
- Introduction
- Published genomes of Coffea species
- Protein sequences show variation between coffee species
- Genomic information of Coffea species published in the public domains
- C-value (genome size) of Coffea species
- Genes of caffeine biosynthesis in Coffea species
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 7. Caffeine-free species in the genus Coffea
- Introduction
- Caffeine content, botanical classification, and geographical distribution of the species
- Genetic control of caffeine biosynthesis
- Caffeine content and duration of the flowering-fruiting period
- Summary points
- Chapter 8. Characterization of coffee genes involved in isoprenoid and diterpene metabolic pathways
- Introduction
- Overview of the isoprenoid metabolic pathway
- Chemical composition and biochemical analysis of diterpenes
- Regulatory enzymes and candidate genes involved in isoprenoid and diterpene biosynthesis
- Conclusions
- Summary points
- Chapter 9. The antioxidant system in coffee
- Introduction
- Conclusions
- Summary points
- Section II. Production and processing
- Chapter 10. Origin, properties, and possibilities of the use and reuse of spent coffee grounds
- Introduction
- Coffee processing
- Coffee by-products
- General composition of spent coffee grounds
- Potential applications of spent coffee grounds
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 11. Coffee beans and processing
- Introduction
- The mode of processing influences the coffee quality
- Coffee seeds exhibit an active metabolism during processing
- Seed germination in the course of green coffee processing
- Green coffee beans suffer drought stress while drying
- Material differences in differentially processed green coffees
- Deliberately influencing the metabolism of green coffee to improve its quality
- Conclusion
- Summary points
- Chapter 12. Postharvest changes in coffee: A focus on chlorogenic acids and antioxidant activities
- Introduction
- Effects of postharvest processing on CGAs and antioxidant activities
- Conclusions
- Other health effects of coffee
- Mini-dictionary of terms
- Summary points
- Chapter 13. Changes in coffee beans during roasting
- Introduction
- Components in green coffee beans
- Components in roasted coffee beans
- Roasting degrees
- Changes in caffeine
- Changes in carbohydrates
- Changes in chlorogenic acids
- Changes in trigonelline
- Changes in proteins and free amino acids
- Formation of aroma components
- Torrefacto roasting
- Conclusion
- Other health effects
- Mini-dictionary of terms
- Summary points
- Chapter 14. Trace levels of plant protection products derived from coffee roasting instead of agricultural practices
- Introduction
- Furfural
- Mepiquat
- 2-Phenylphenol
- Folpet/phthalimide
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 15. Assessing the effects of coffee roasting conditions on sensory preferences: A narrative review
- Introduction
- Prominent characteristics of coffee bean Arabica, Robusta, and Liberica
- Coffee roasting quality parameters
- Coffee sensory characteristics and global trends of coffee consumption
- Mini-dictionary of terms
- Summary points
- Chapter 16. Espresso coffee preparation and the importance of volatiles
- Summary points
- Introduction
- An overview of EC aroma
- EC machine parameters and their influence on the EC flavor
- Conclusions
- Chapter 17. The aroma of instant coffee: Its release and modulation by encapsulation
- Introduction
- Instant coffee processing
- The aroma of coffee
- Aroma composition of instant coffee in relation to regular coffee
- Aroma release from reconstitutes instant coffee
- The forces driving VOC release
- Kinetic release of aroma from instant coffee
- Modulation of aroma release through aroma encapsulation
- Conclusion and outlook
- Summary points
- Compositional, nutritional, and metabolic aspects
- A. Compositional
- Chapter 18. The compositional differences between wild and domesticated coffee
- Introduction
- Alkaloids of coffee
- Caffeine content in coffee
- Trigonelline content
- Sucrose content
- Chlorogenic acids
- Kahweol and Cafestol
- Correlation between secondary metabolites of coffee plants, their origin, and processing
- Flavor alterations between different coffee species
- Conclusion
- Mini-Dictionary of terms
- Summary points
- Chapter 19. Components in coffee, their concentrations, and methods of analysis
- Introduction
- Main ingredients of coffee
- Methods of analysis
- Phenolic acids and their derivatives
- Method of analysis
- Flavonoids
- Method of analysis
- Terpenoids
- Method of analysis
- Melanoidins
- Method of analysis
- Flavor substances
- Method of analysis
- Mini-dictionary terms
- Summary points
- Chapter 20. Nuclear magnetic resonance spectroscopic profiles of coffee
- Introduction
- Foundations of NMR
- Use of chemometrics in NMR studies of coffee
- Studies of coffee profiles using solution NMR
- NMR experiments performed with whole coffee samples
- Other NMR studies of coffee-related materials
- Mini-dictionary of terms
- Summary points
- Chapter 21. Derivatives of atractyligenin in coffee
- Introduction
- Derivatives of carboxyatractyligenin and atractyligenin in coffee
- Developments in quantitative analysis of carboxyatractyligenin and atractyligenin derivatives
- Bioactivity of carboxyatractyligenin and atractyligenin derivatives
- Atractyligenin and synthetic derivatives as potential therapeutic compounds
- Metabolites of atractyligenin derivatives from roasted coffee consumption
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 22. Chlorogenic acids in different coffees
- Introduction
- Chemical structure of CGAs
- Variability of CGAs in coffee varieties
- Influence of processing on CGA levels
- Geographical and environmental effects on CGAs
- Flavor contributions of CGAs
- Analytical methods and quantification of CGAs
- Commercial significance and future trends
- Conclusion
- Summary points
- Chapter 23. Diterpenes in coffee
- Introduction
- Diterpenes biosynthesis and biological activities
- Diterpenes chemistry
- Diterpene content in coffee
- Diterpenes as molecular markers
- New and minor diterpenes
- Diterpenes and human health
- Mini-dictionary of terms
- Summary points
- Chapter 24. Influence of melanoidins on aroma perception of coffee
- Introduction
- High molecular weight coffee constituents: Melanoidins
- Interactions between aroma compounds and nonvolatile coffee constituents
- Noncovalent interactions between volatile and nonvolatile coffee constituents
- Analyses of odorant melanoidin interactions by means of human sensory evaluations and NMR-based screening
- Monitoring time dependency of odorant–melanoidin interactions via quantitative NMR spectroscopy and determination of structure–activity relationships
- Determination of melanoidin composition and correlation with aroma binding activity
- Mini-dictionary of terms
- Summary points
- Chapter 25. Coffee dietary fiber: Features and hypocholesterolemic effects
- Introduction
- Coffee brew high molecular weight compounds: Chemical composition
- Effect of coffee processing on modification of high molecular weight carbohydrates
- Coffee fiber hypocholesterolemic potential: Cholesterol bioaccessibility and bioavailability
- Gut microbiota modulation and cholesterol homeostasis
- Coffee consumption and risk of cardiovascular disease
- Hypercholesterolemic risk conundrum: The case of coffee diterpenes
- Conclusions
- Mini-dictionary of terms
- Summary points
- B. Nutritional and metabolic
- Chapter 26. Linking coffee consumption and vitamin D status
- Introduction
- Types and composition of coffee
- Consumption of coffee
- Coffee and health consequences
- Potential health benefits of coffee
- Potential adverse health effects of coffee
- Vitamin D: An overview
- Vitamin D deficiency
- Vitamin D deficiency and health consequences
- Vitamin D deficiency and bone health
- Correlation between coffee consumption and vitamin D
- Summary points
- Chapter 27. Coffee and the glycemic response in obesity
- Introduction
- Short-term effect of coffee consumption on glycemic response
- Long-term effect of coffee consumption on glycemic response
- Mechanisms of coffee consumption on glycemic response
- Summary points
- Mini-dictionary of terms
- Chapter 28. Coffee intake and reduced Dual-Energy X-ray absorptiometry quantification of adiposity
- Introduction
- Relationship between coffee and caffeine intake and body adiposity
- DXA as a measure of body adiposity
- Studies linking coffee intake with DXA measurements
- Potential mechanisms underpinning the Coffee-DXA relationship
- Further research needed
- Conclusion
- Mini-dictionary of terms
- Summary points (5 bulleted format)
- Chapter 29. Linking metabolic syndrome and coffee drinking
- Metabolic syndrome
- Coffee and MetS
- Coffee and MetS components
- Coffee and obesity
- Coffee and diabetes and insulin resistance
- Coffee and dyslipidemia
- Coffee and hypertension
- Discrepancy in findings
- Mini-dictionary of terms
- Summary points
- Chapter 30. The cardiovascular effects of coffee consumption: An overview
- Introduction
- Coffee and lipid disorders
- Coffee and arterial hypertension
- Coffee and atrial fibrillation
- Coffee and atherosclerotic cardiovascular disease
- Coffee and heart failure
- Coffee and cardiovascular mortality
- Conclusions
- Summary points
- Mini-dictionary of terms
- Other health effects of coffee or extracts
- General aspects of the effects of coffee
- A. Organs and conditions
- Chapter 31. Highlights in the history of the science of coffee and health
- Introduction
- Coffee, health, and science
- The main bioactive substances in coffee
- Coffee and nutrition
- Therapeutical use
- Implication of the amount consumed
- Coffee enema
- Associated habits and health
- Concluding remarks
- Summary points
- Chapter 32. A Comprehensive Review of Coffee's Health Impacts on Older Adults
- Introduction of coffee
- Benefits of coffee intake
- Health issues among older adults
- The coffee intake habits among older adults
- Coffee intake on older adults' health
- Effects of coffee polyphenols and caffeine on health issues
- Negative influences of coffee intake on older adults' health
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 33. Coffee and arterial stiffness
- Introduction
- Arterial stiffness
- Arterial stiffness and chronic diseases: A bidirectional relationship
- Interventions to reduce arterial stiffness
- Effects of coffee on arterial stiffness
- Mechanisms
- Other health effects of coffee or extracts
- Mini-dictionary of terms
- Summary points
- Chapter 34. Coffee and its metabolites in relation to asthma and lung function
- Introduction
- Current evidence linking coffee and its metabolites to asthma
- Current evidence linking coffee and its metabolites to lung function
- Potential mechanisms for the link between coffee and lung health
- Conclusions and future directions
- Mini-dictionary of terms
- Summary points
- Chapter 35. Head and neck cancer and the protective associations with coffee consumption
- Epidemiology and risk factors for the development of head and neck cancer
- Coffee and its protective elements associated with head and neck cancer
- Mini-dictionary of terms
- Summary Points
- Chapter 36. Investigations of the effects of coffee in chemotherapy
- Introduction
- Investigations on coffee-mediated improvement of chemotherapeutic side effects
- Investigations on coffee-mediated enhancement of chemotherapeutic efficacy
- Mini-dictionary of terms
- Summary points
- Chapter 37. Coffee, caffeine, and delaying of cataract development
- Introduction
- Ocular pharmacology of caffeine
- Potential protective effect of caffeine
- Summary
- Summary points
- Chapter 38. Coffee and periodontal health: To protect or to harm?
- Introduction
- Periodontal tissue
- Periodontal diseases
- The effect of coffee on periodontal health
- Other oral and dental health effects of coffee
- Mini-dictionary of terms
- Summary points
- Chapter 39. Effects of coffee on gut microbiota in health and diseases
- Introduction
- Effects of coffee on the gut microbiota
- Effect of coffee on gastrointestinal infections and immunity
- Coffee effect on gastrointestinal motility: A role of microbiota?
- Coffee effect on the gut–brain axis: A role of microbiota?
- Coffee effect on absorption and nutrition: a role of microbiota?
- Other health effects of coffee or extracts: Effect of coffee on oral microbiome
- Mini-dictionary of terms
- Summary points
- B. Cells and cellular biology
- Chapter 40. Coffee and effects on platelets
- Introduction
- Atherothrombosis: Involvement of platelets
- Participation of platelets in atherothrombosis
- Coffee and prevention of cardiovascular diseases
- Cardiovascular effect of coffee consumption in humans
- Bioactive compounds of coffee and antiplatelet activity
- Antiplatelet mechanism of action
- Summary points
- Chapter 41. Human genetics and caffeine: Functional single-nucleotide polymorphism and response to caffeine intake
- Introduction
- Polymorphism of genes involved in response to caffeine
- Gene polymorphism and differential response to caffeine or coffee intake
- Mini-dictionary of terms
- Summary points
- Chapter 42. Coffee compounds and their effects on miRNAs during gastrointestinal health and disease
- Introduction
- miRNAs: Small molecules with great responsibilities
- Coffee compounds and miRNAs involved in gastrointestinal diseases
- Conclusions and future perspectives
- Mini-dictionary of terms
- Summary points
- Chapter 43. Chronotype, circadian rhythm, and coffee consumption
- Introduction
- Circadian rhythm
- Factors influencing circadian rhythm
- How does coffee/caffeine affect circadian rhythm?
- Chronotype
- Conclusion
- Other health effects of coffee/caffeine
- Mini-dictionary of terms
- Summary points
- Chapter 44. Coffea robusta extracts and antibacterial effects: Escherichia coli and beyond
- Introduction of coffee
- Benefit of coffee consumption
- Coffee properties
- The roasting process
- Antibacterial, resistance, and coffee
- Antibacterial against E. coli and another bacteria
- Antibacterial mechanism
- Melanoidin antibacterial mechanism
- Caffeine antibacterial mechanism
- Phenol antibacterial mechanism
- Miscellaneous antibacterial mechanism
- Coffee extract susceptibility in different bacteria
- Mini-dictionary of terms
- Summary points
- Section V. Focused areas, specific coffee components, and effects
- Chapter 45. Cafestol: Impact of coffee diterpene on cancer cells and associated antiinflammatory response
- Introduction
- Chemical aspects of cafestol and its relationship with biological effects
- Cafestol is a COX-2 inhibitor
- Cafestol action on endothelial cells: The bridge between antiinflammatory and antiangiogenic activity
- Opposite signaling modulated by cafestol: NF-κB and Nrf2
- Proapoptotic action of cafestol and its potential as a therapeutic sensitizer
- Natural products as adjuvants. The diversity of molecular targets helps in the sensitization of resistant cells
- Synergism of cafestol and kahweol for antitumor effect – from the drink to the biological target
- Conclusion
- Other health effects of coffee extracts
- Mini-dictionary of terms
- Summary points
- Chapter 46. Caffeic acid and derivatives as antiviral agents
- Introduction
- Antiviral effects of caffeic acid and derivatives
- Human immunodeficiency virus
- Herpes simplex virus
- Influenza A virus
- Severe acute respiratory syndrome coronavirus 2
- Polio virus
- Enterovirus 71
- Respiratory syncytial virus
- Canine distemper virus
- Adenovirus
- Summary and future perspective
- Other health effects of coffee polyphenols
- Mini-dictionary of terms
- Summary points
- Chapter 47. Hypertension and effects of coffee-derived analytes caffeic and chlorogenic acids
- Introduction
- Coffee, caffeic acid (CAA), and chlorogenic acid (CHA) exhibit blood-lowering ability
- Coffee and its derivatives and other health effects
- Mini-dictionary of terms
- Summary points
- Chapter 48. Sleep and the impact of high caffeine consumption: Implications for coffee consumption
- Introduction
- Caffeine—coffee and caffeinated beverages
- Cellular mechanisms of caffeine action
- What is a safe amount of caffeine to consume?
- How does caffeine affect sleep?
- The impact of caffeine deprivation and withdrawal
- The caffeine paradox—caffeine gets people sleepy
- Caffeine and sleep disordered breathing
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 49. The role of caffeine in health via comparisons between caffeinated and decaffeinated coffee: A focus on colon cancer
- Introduction
- Caffeine, coffee, and cancer: Epidemiological evidence
- Experimental evidence
- Mechanisms
- Some methodological issues
- Other health effects of coffee
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 50. Caffeine, coffee and effects on the liver
- Introduction
- Studies in humans
- Studies in experimental models
- Other health effects of caffeine
- Mini-dictionary of terms
- Summary points
- Chapter 51. Caffeine and its molecular and physiological effects on skeletal muscle
- Introduction
- Molecular effects of caffeine on skeletal muscle
- Physiological effects of caffeine on skeletal muscle
- Individual variability and considerations
- Conclusion
- Summary points
- Chapter 52. Caffeine cardiovascular toxicity: too much of a good thing—an update
- Introduction
- Caffeine and the heart
- Summary points
- Chapter 53. Chlorogenic acid in energy metabolism on efficacy and mechanisms of action
- Introduction
- CGA and health outcomes
- Prevention and/or treatment of obesity/metabolic syndrome
- Antiatherosclerotic properties of CGA
- Effects of CGA against myocardial infarction
- Effects of CGA on neurological diseases
- Conclusions and future perspective
- Mini-dictionary of terms
- Summary points
- Chapter 54. Chlorogenic acid utilization in the diabetic and prediabetic states
- Introduction
- Diabetes mellitus
- Treatment of diabetes
- Nonpharmacological treatments
- Coffee
- Coffee components
- Coffee as a source of CGAs
- Changes in coffee components
- Chemical composition of coffee
- Effects of chlorogenic acid
- Studies on chlorogenic acid
- Other health effects of coffee
- Mini-dictionary of terms
- Summary points
- Chapter 55. Nanoencapsulation of coffee: Controlled release of chlorogenic acid
- Introduction
- Nanoencapsulation system and food industry
- Dietary supplements/nutraceuticals and functional foods
- Nanoencapsulation of green coffee, characterization, and its controlled release
- Nanoencapsulation CGA from green coffee extract by nano spray drying
- Nanoencapsulation of green coffee extract by spray drying
- Characterization of optimized green coffee nanoparticles
- Effect of pH on nanoparticles
- Thermophysical properties
- Structural characterization (SEM, AFM, and XRD analysis)
- In vitro release profile of CGA and antioxidant activity after simulated gastro intestinal digestion
- Antioxidant capacity
- Storage stability of the nanoencapsulated green coffee extract
- Chemical properties (total polyphenols, CGA, and antioxidant activity)
- Conclusion
- Summary points
- Chapter 56. ent-Kaurane-type diterpenes as components in coffee and their biological activities
- Introduction
- Species of ent-kaurane-type diterpenes in coffee
- Biological activities of ent-kaurane-type diterpenes from coffee
- Other health effects of diterpenes from coffee
- Mini-dictionary of terms
- Summary points
- Chapter 57. Role of trigonelline, a bioactive alkaloid in coffee, for kidney stone prevention
- Introduction
- Coffee bean as a natural source of trigonelline and factors affecting its trigonelline content (coffee species, postharvest process, storage condition, roasting process, and brewing method)
- Pharmacokinetics of trigonelline
- Beneficial effects of trigonelline in kidney diseases
- The role of trigonelline for kidney stone prevention
- Conclusion
- Summary points
- Section VI. Behavior, brain, and neurological systems
- Chapter 58. Coffee and caffeine: Impact on mood, cognition, and physical activity
- Introduction
- The effects of caffeine on mood
- The effects of caffeine on cognition
- The effects of caffeine on physical activity
- Other psychomotor effects of coffee compounds
- Mini-dictionary of terms
- Summary points
- Chapter 59. Coffee consumption: Links with anxiety and depression
- Introduction
- Coffee and depression
- Coffee and anxiety
- Relationship of caffeine dependence and caffeine-related disorders with depression and anxiety
- The role of genetic variations and individual differences
- Conclusion
- Other health effects of coffee
- Mini-dictionary of terms
- Summary points
- Chapter 60. The brain response to coffee consumption: Electroencephalogram (EEG) changes and implications
- Introduction
- Effects of coffee and caffeine consumption on the CNS
- EEG effects
- Conclusions and future directions
- Other electroencephalography effects of coffee
- Mini-dictionary of terms
- Summary points
- Chapter 61. Caffeine and potential use in Alzheimer’s disease
- Introduction
- The influence of caffeine on the molecular mechanisms underlying AD
- Effect of caffeine analyzed in preclinical mouse models
- Clinical studies examining the influence of caffeine on AD
- Longitudinal study finds protective range of coffee consumption with reference to dementia prevalence
- Effect of coffee consumption on amyloid-β deposition in elderly humans
- Metaanalyses find support for neuroprotective effects from coffee consumption in majority of studies
- Effects of coffee on risk factors contributing to AD
- Mini-dictionary of terms
- Summary points
- Chapter 62. Chlorogenic acid as a neuroprotectant: A focus on Parkinson's disease
- Introduction
- Parkinson's disease overview
- Role of coffee components in PD
- Role of chlorogenic acid (CGA) in PD
- Clinical trials of CGA
- Additional health effects of CGA
- Conclusion
- Summary points
- Chapter 63. Investigating kahweol as a component of coffee: Effects on brain mitochondria
- Introduction
- KW and mitochondria
- Conclusion and future directions
- Mini-dictionary of terms
- Summary points
- Chapter 64. Coffee and the brain–gut axis
- Introduction
- Studies on coffee
- Studies involving coffee components
- Conclusions
- Mini-dictionary of terms
- Summary points
- Section VII. Adverse components and adverse effects of coffee and related products
- Chapter 65. Exploring the relationship between caffeine consumption and atrial fibrillation: Unraveling the connection
- Background
- Mechanisms linking caffeine and atrial fibrillation
- Metaanalysis of studies on coffee and caffeine
- Clinical studies on caffeine and atrial fibrillation
- Future perspective
- Conclusions
- Summary block point
- Chapter 66. Formation, level, reduction methods, and health risk assessment of acrylamide in coffee products
- Introduction
- Acrylamide
- Acrylamide formation mechanism in coffee products
- Acrylamide levels in coffee products
- Mitigation strategies of acrylamide in coffee products
- Acrylamide exposure and risk assessment from consumption of coffee products
- Chapter 67. The mycotoxin ochratoxin A: Levels in coffee
- Introduction
- General data of ochratoxin A
- Determination of ochratoxin A in coffees
- Factors influencing coffee contamination by ochratoxin A
- Review of OTA in coffees around the world
- Ochratoxin A in Brazilian coffees
- Good production practices for a coffee free of OTA
- Mini-dictionary of terms
- Summary points
- Other health effects of coffee or extracts
- Chapter 68. Toxic compounds in coffee: Polycyclic aromatic hydrocarbons
- Introduction
- PAHs and coffee roasting
- PAH chemistry and biological activity
- Regulatory aspects
- PAH determination in coffee
- PAHs and coffee by-products
- Conclusions
- Mini-dictionary of terms
- Summary points
- Section VIII. Comparison of coffee and tea
- Chapter 69. Comparing coffee and tea consumption regarding DNA methylation
- Introduction
- DNA methylation patterns—Epigenetic gene expression regulator
- The biological relevance of DNA methylation
- Similar and different effects of coffee and green tea compounds on DNA methylation
- The effects of coffee and green tea compounds on signal transducers resulting in DNA methylation patterns relevant to cancer biology
- The other disease-preventing effects of green tea and coffee
- Harmful effects of caffeine during pregnancy
- Mini-dictionary of terms
- Summary points
- Chapter 70. Coffee and tea consumption and pregnancy
- Physiology of pregnancy
- Fluid recommendation during pregnancy
- Coffee and tea recommendations during pregnancy
- Epidemiological evidence on the impact of coffee consumption during pregnancy
- Epidemiological evidence on the impact of tea during pregnancy
- Mechanisms and methodological issues
- Other health effects of coffee and tea
- Mini-dictionary of terms
- Summary points
- Section IX. Byproducts of coffee production and their uses
- Chapter 71. Uses of industrially produced spent coffee grounds
- Introduction
- Carbohydrates
- Lipids and fatty acids
- Proteins and biopeptides
- Alkaloids
- Conclusions
- Summary points
- Chapter 72. Prebiotic potential of coffee and coffee by-products
- Introduction
- Human gut microbiota
- Biotransformation of prebiotics and coffee components before reaching the gut microbiota
- Impact of prebiotics on the gut microbiota
- Impact of coffee and coffee by-products on gut microbiota
- Impact of specific components of coffee and its by-products on gut microbiota
- Can the prebiotic effect of coffee and its components modulate the microbiota–gut–brain axis?
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 73. Coffee silverskin: potential health benefits and current applications
- Introduction
- Potential health benefits of coffee silverskin
- Current applications of coffee silverskin
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 74. In silico molecular modeling of coffee silverskin
- Introduction
- Bioinformatic tools
- Molecular docking
- Innovation in molecular docking
- Molecular dynamic simulation
- ADMET and drug-likeness of small molecules (ADMET-M)
- Databases
- In silico molecular modeling of compounds present in coffee silverskin
- Conclusion
- Mini-dictionary of terms
- Summary points
- Acknowledgments
- Section X. Resources and selective methods
- Chapter 75. Highlights for the advanced analysis of bioactive compounds in coffee
- Introduction
- A brief overview of coffee's composition
- Key analytical techniques
- Analytical technique combination
- Chemometrics for multivariate associations
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 76. Methods for extracting bioactive compounds from coffee and its by-products
- Introduction
- Bioactive compounds present in coffee and coffee by-products
- Extraction methods
- Alternative solvents for extracting bioactive compounds from coffee and coffee by-products
- Downstream processing of bioactive compounds from coffee and coffee by-products
- Conclusion
- Summary points
- Chapter 77. Genetic methods to evaluate evidence for causal effect of coffee on health
- Introduction
- Mendelian randomization
- Genetic variants associated with coffee and caffeine consumption
- Genetic evidence for causal effect of coffee on health
- Conclusion
- Mini-dictionary of terms
- Summary points
- Chapter 78. Caffeic and chlorogenic acid in coffee and methods for their detection
- Introduction
- The chemical composition of coffee
- The effects of coffee on health due to caffeic acid and chlorogenic acid
- Quality and authenticity control of coffee
- Analytical methods for the detection of caffeic and chlorogenic acid in coffee
- Electrochemical methods for the detection of caffeic and chlorogenic acid in coffee
- Conclusions
- Mini-dictionary of terms
- Summary points
- Chapter 79. Ochratoxin A in coffee: occurrence, health impact, regulation, and analytical methods
- Introduction
- Chemical and physical characterization of OTA
- OTA-producing molds
- OTA occurrence
- Ochratoxin A in different types of coffee
- Economic impact of OTA
- Health impact of OTA
- OTA regulations
- OTA analysis
- Recent advanced for detection OTA in coffee
- Summary points
- Chapter 80. Profiling new genotypes of coffee sensory, compositional, and biological aspects
- Summary points
- Introduction
- Development of new coffees and future trends
- Species and varieties
- Origin of coffee aromas and flavors
- Maturation degree
- Formation of aromas and flavors
- Sensory evaluation of coffees
- Chemical composition and relationship with coffee quality
- Coffee roasting and its influence on quality and biological activity
- Coffee maturation and its effects on quality and biological activity
- Chemometric approach in the analysis of the relationship between composition
- Chapter 81. Recommended resources for coffee in health and disease prevention
- Introduction
- Resources
- Other resources
- Summary Points
- Index
- Edition: 2
- Published: September 14, 2024
- Imprint: Academic Press
- No. of pages: 1000
- Language: English
- Hardback ISBN: 9780443138683
- eBook ISBN: 9780443138690
VP
Victor R Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UKVP
Vinood Patel
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications.
Affiliations and expertise
Reader, Clinical Biochemistry, University of Westminster, London, UKRead Coffee in Health and Disease Prevention on ScienceDirect