
Clinical Chemistry
- 10th Edition - July 18, 2025
- Imprint: Elsevier
- Authors: William J. Marshall, Márta Lapsley, Andrew Day, Kate Shipman
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 8 3 8 9 - 5
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 8 7 3 2 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 8 4 4 3 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 8 4 4 2 - 7
Many diseases have a biochemical basis, and many cause biochemical abnormalities. Clinical biochemistry (also known as chemical pathology) thus plays an important part in the… Read more
Purchase options

Many diseases have a biochemical basis, and many cause biochemical abnormalities. Clinical biochemistry (also known as chemical pathology) thus plays an important part in the diagnosis and management of many conditions. Clinical Chemistry, now in its tenth edition, covers these topics in detail.
Each chapter covers the relevant basic science, along with discussion on diagnostic techniques and patient management, combined with practical case histories and quick-reference summaries.
This book has been loved by generations of medical and biomedical science students the world over for its clear and engaging writing style and relevance to practice. It has now been fully updated throughout to reflect the latest field developments.
Each chapter covers the relevant basic science, along with discussion on diagnostic techniques and patient management, combined with practical case histories and quick-reference summaries.
This book has been loved by generations of medical and biomedical science students the world over for its clear and engaging writing style and relevance to practice. It has now been fully updated throughout to reflect the latest field developments.
- Highly relevant to clinical practice – extensive use of clinical case studies, with red flags for results of immediate concern
- Covers the basic science of biochemistry while avoiding unnecessary detail
- Suitable for medical students as well as students and practitioners of clinical and biomedical science - ideal for integrated and problem-based curricula
- Clear and engaging writing style make understanding and learning easy
- Highly illustrated throughout – illustrations, charts and flow diagrams make challenging concepts memorable
- Complementary enhanced eBook including additional cases and self-assessment material
Medical students; trainee clinical scientists; biomedical scientists
1 An introduction to biochemistry and cell biology
2 Biochemical investigations in clinical medicine
3 Water, sodium and potassium
4 Hydrogen ion homoeostasis and blood gases
5 The kidneys
6 The liver
7 The gastrointestinal tract
8 Clinical nutrition
9 The hypothalamus and the pituitary gland
10 The adrenal glands
11 The thyroid gland
12 The gonads
13 Disorders of carbohydrate metabolism
14 Calcium, phosphate and magnesium
15 Bones and joints
16 Plasma proteins and enzymes
17 Lipids, lipoproteins and cardiovascular disease
18 Muscles, nerves and psychiatric disorders
19 Inherited metabolic diseases
20 Metabolic aspects of malignant disease
21 Biochemical aspects of therapeutic drug monitoring and toxicology
22 Clinical chemistry in children
Appendix
Adult reference ranges
Index
2 Biochemical investigations in clinical medicine
3 Water, sodium and potassium
4 Hydrogen ion homoeostasis and blood gases
5 The kidneys
6 The liver
7 The gastrointestinal tract
8 Clinical nutrition
9 The hypothalamus and the pituitary gland
10 The adrenal glands
11 The thyroid gland
12 The gonads
13 Disorders of carbohydrate metabolism
14 Calcium, phosphate and magnesium
15 Bones and joints
16 Plasma proteins and enzymes
17 Lipids, lipoproteins and cardiovascular disease
18 Muscles, nerves and psychiatric disorders
19 Inherited metabolic diseases
20 Metabolic aspects of malignant disease
21 Biochemical aspects of therapeutic drug monitoring and toxicology
22 Clinical chemistry in children
Appendix
Adult reference ranges
Index
- Edition: 10
- Published: July 18, 2025
- Imprint: Elsevier
- Language: English
WM
William J. Marshall
Affiliations and expertise
Emeritus Reader in Clinical Biochemistry, Kings College London, London, UK; formerly Consultant Clinical Biochemist and Clinical Director of Pathology, The London Clinic, London, UK.ML
Márta Lapsley
Affiliations and expertise
Consultant Chemical Pathologist, Epsom and St. Helier University Hospitals NHS Trust, Epsom, Surrey, UKAD
Andrew Day
Affiliations and expertise
Consultant in Clinical Biochemistry and Metabolic Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UKKS
Kate Shipman
Affiliations and expertise
Consultant Chemical Pathologist, University Hospitals Sussex NHS Foundation Trust, Chichester, UK