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Clinical Chemistry

  • 10th Edition - March 9, 2025
  • Latest edition
  • Authors: William J. Marshall, Márta Lapsley, Andrew Day, Kate Shipman
  • Language: English

Many diseases have a biochemical basis, and many cause biochemical abnormalities. Clinical biochemistry (also known as chemical pathology) thus plays an important part in the… Read more

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Description

Many diseases have a biochemical basis, and many cause biochemical abnormalities. Clinical biochemistry (also known as chemical pathology) thus plays an important part in the diagnosis and management of many conditions. Clinical Chemistry, now in its tenth edition, covers these topics in detail.

Each chapter covers the relevant basic science, along with discussion on diagnostic techniques and patient management, combined with practical case histories and quick-reference summaries.

This book has been loved by generations of medical and biomedical science students the world over for its clear and engaging writing style and relevance to practice. It has now been fully updated throughout to reflect the latest field developments.

Key features

  • Highly relevant to clinical practice – extensive use of clinical case studies, with red flags for results of immediate concern
  • Covers the basic science of biochemistry while avoiding unnecessary detail
  • Suitable for medical students as well as students and practitioners of clinical and biomedical science - ideal for integrated and problem-based curricula
  • Clear and engaging writing style make understanding and learning easy
  • Highly illustrated throughout – illustrations, charts and flow diagrams make challenging concepts memorable
  • Complementary enhanced eBook including additional cases and self-assessment material

Readership

Medical students; trainee clinical scientists; biomedical scientists

Table of contents

1. An introduction to biochemistry and cell biology

2. Biochemical investigations in clinical medicine

3. Water, sodium and potassium

4. Hydrogen ion homoeostasis and blood gases

5. The kidneys

6. The liver

7. The gastrointestinal tract

8. Clinical nutrition

9. The hypothalamus and the pituitary gland

10. The adrenal glands

11. The thyroid gland

12. The gonads

13. Disorders of carbohydrate metabolism

14. Calcium, phosphate and magnesium

15. Bones and joints

16. Plasma proteins and enzymes

17. Lipids, lipoproteins and cardiovascular disease

18. Muscles, nerves and psychiatric disorders

19. Inherited metabolic diseases

20. Metabolic aspects of malignant disease

21. Biochemical aspects of therapeutic drug monitoring and toxicology

22. Clinical chemistry in children

Product details

  • Edition: 10
  • Latest edition
  • Published: July 18, 2025
  • Language: English

About the authors

WM

William J. Marshall

Affiliations and expertise
Emeritus Reader in Clinical Biochemistry, Kings College London, London, UK; formerly Consultant Clinical Biochemist and Clinical Director of Pathology, The London Clinic, London, UK.

ML

Márta Lapsley

Affiliations and expertise
Consultant Chemical Pathologist, Epsom and St. Helier University Hospitals NHS Trust, Epsom, Surrey, UK

AD

Andrew Day

Affiliations and expertise
Consultant in Clinical Biochemistry and Metabolic Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UK

KS

Kate Shipman

Affiliations and expertise
Consultant Chemical Pathologist, University Hospitals Sussex NHS Foundation Trust, Chichester, UK