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Ciliary Function in Mammalian Development

  • 1st Edition, Volume 85 - December 11, 2008
  • Latest edition
  • Editor: Bradley Yoder
  • Language: English

Cilia--the tiny hairlike structures on the surface of cells—-have recently been identified as playing a role in a variety of disease and developmental disorders. Absent or… Read more

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Description

Cilia--the tiny hairlike structures on the surface of cells—-have recently been identified as playing a role in a variety of disease and developmental disorders. Absent or defective cilia in certain cells can cause infertility, blindness, kidney disease, and lung disease. This volume presents recent findings in cilia research and current thought on the role of cilia in disease and developmental abnormalities.

Readership

Researchers in cell, developmental, and molecular biology as well as researchers in genetics

Table of contents

1. Assembly and function of the basal body
Susan Dutcher

2. Cilia assembly and maintenance
Lotte Pedersen and Joel Rosenbaum

3. Origin and Evolution of the cilium
Peter Satir, David R. Mitchell, and Gaspar Jekely

4. Transport and targeting of ciliary proteins
Gregory Pazour and Robert Bloodgood

5. Tubulin Modifications and Regulation of Cilia formation and function
Jacek Gaertig

6. Ciliary functions in early embryo patterning and axis formation
Martina Brueckner

7. Cilia mediated control of Wnt signaling activity
Nicholas Katsanis

8. Ciliary function in regulating planar cell polarity of the inner ear
Ping Chen

9. Ciliary role in hedgehog signaling activity
Jeremy Reiter

10. Cilia regulation of cell migration during development and tissue repair
Soren Christensen

11. Cilia involvement in patterning and maintenance of bone
Rosa Serra and Courtney Haycraft

12. IFT in photoreceptor assembly and function
Joe Besharse

13. Ciliary dysfunction disease
Neeraj Sharma and Bradley Yoder

Product details

  • Edition: 1
  • Latest edition
  • Volume: 85
  • Published: December 11, 2008
  • Language: English

About the editor

BY

Bradley Yoder

Affiliations and expertise
University of Alabama, Birmingham, USA

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