Cell Biology
With STUDENT CONSULT Access
- 2nd Edition - November 7, 2013
- Authors: Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz
- Language: English
- eBook ISBN:9 7 8 - 1 - 4 5 5 7 - 2 6 4 7 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 2 4 8 4 1 - 9
A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It… Read more
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A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures.
- Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject.
- Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions.
- Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states.
- Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale.
- Explains how molecular and cellular structures evolved in different organisms.
- Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout.
- Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles—to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more!
SECTION I: Introduction to Cell Biology
CHAPTER 1
Introduction to Cells
CHAPTER 2
Evolution of Life on Earth
SECTION II: Chemical and Physical Background
CHAPTER 3
Molecules: Structures and Dynamics
CHAPTER 4
Biophysical Principles
CHAPTER 5
Macromolecular Assembly
CHAPTER 6
Research Strategies
SECTION III: Membrane Structure and Function
CHAPTER 7
Membrane Structure and Dynamics
CHAPTER 8
Membrane Pumps
CHAPTER 9
Membrane Carriers
CHAPTER 10
Membrane Channels
CHAPTER 11
Membrane Physiology
SECTION IV: Chromatin, Chromosomes, and the Cell Nucleus
CHAPTER 12
Chromosome Organization
CHAPTER 13
DNA Packaging in Chromatin and Chromosomes
CHAPTER 14
Nuclear Structure and Dynamics
SECTION V: Central Dogma: From Gene to Protein
CHAPTER 15
Gene Expression
This chapter was written by Jeffrey L. Corden
CHAPTER 16
Eukaryotic RNA Processing
This chapter was written by David Tollervey
CHAPTER 17
Protein Synthesis and Folding
SECTION VI: Cellular Organelles and Membrane Trafficking
CHAPTER 18
Posttranslational Targeting of Proteins
CHAPTER 19
Mitochondria, Chloroplasts, Peroxisomes
CHAPTER 20
Endoplasmic Reticulum
CHAPTER 21
Secretory Membrane System and Golgi Apparatus CHAPTER 22
Endocytosis and the Endosomal Membrane System CHAPTER 23
Degradation of Cellular Components
SECTION VII
Signaling Mechanisms
CHAPTER 24
Plasma Membrane Receptors
CHAPTER 25
Protein Hardware for Signaling
CHAPTER 26
Second Messengers
CHAPTER 27
Integration of Signals
SECTION VIII: Cellular Adhesion and the Extracellular Matrix
CHAPTER 28
Cells of the Extracellular Matrix and Immune System
CHAPTER 29
Extracelluar Matrix Molecules
CHAPTER 30
Cellular Adhesion
CHAPTER 31
Intercellular Junctions
CHAPTER 32
Connective Tissues
SECTION IX: Cytoskeleton and Cellular Motility
CHAPTER 33
Actin and Actin-Binding Proteins
CHAPTER 34
Microtubules and Centrosomes
CHAPTER 35
Intermediate Filaments
CHAPTER 36
Motor Proteins
CHAPTER 37
Intracellular Motility
CHAPTER 38
Cellular Motility
CHAPTER 39
Muscles
SECTION X: Cell Cycle
CHAPTER 40
Introduction to the Cell Cycle
CHAPTER 41
G1 Phase and Regulation of Cell Proliferation
CHAPTER 42
S Phase and DNA Replication
CHAPTER 43
G2 Phase and Control of Entry into Mitosis
CHAPTER 44
Mitosis and Cytokinesis
CHAPTER 45
Meiosis
CHAPTER 46
Programmed Cell Death
Glossary
Index
CHAPTER 1
Introduction to Cells
CHAPTER 2
Evolution of Life on Earth
SECTION II: Chemical and Physical Background
CHAPTER 3
Molecules: Structures and Dynamics
CHAPTER 4
Biophysical Principles
CHAPTER 5
Macromolecular Assembly
CHAPTER 6
Research Strategies
SECTION III: Membrane Structure and Function
CHAPTER 7
Membrane Structure and Dynamics
CHAPTER 8
Membrane Pumps
CHAPTER 9
Membrane Carriers
CHAPTER 10
Membrane Channels
CHAPTER 11
Membrane Physiology
SECTION IV: Chromatin, Chromosomes, and the Cell Nucleus
CHAPTER 12
Chromosome Organization
CHAPTER 13
DNA Packaging in Chromatin and Chromosomes
CHAPTER 14
Nuclear Structure and Dynamics
SECTION V: Central Dogma: From Gene to Protein
CHAPTER 15
Gene Expression
This chapter was written by Jeffrey L. Corden
CHAPTER 16
Eukaryotic RNA Processing
This chapter was written by David Tollervey
CHAPTER 17
Protein Synthesis and Folding
SECTION VI: Cellular Organelles and Membrane Trafficking
CHAPTER 18
Posttranslational Targeting of Proteins
CHAPTER 19
Mitochondria, Chloroplasts, Peroxisomes
CHAPTER 20
Endoplasmic Reticulum
CHAPTER 21
Secretory Membrane System and Golgi Apparatus CHAPTER 22
Endocytosis and the Endosomal Membrane System CHAPTER 23
Degradation of Cellular Components
SECTION VII
Signaling Mechanisms
CHAPTER 24
Plasma Membrane Receptors
CHAPTER 25
Protein Hardware for Signaling
CHAPTER 26
Second Messengers
CHAPTER 27
Integration of Signals
SECTION VIII: Cellular Adhesion and the Extracellular Matrix
CHAPTER 28
Cells of the Extracellular Matrix and Immune System
CHAPTER 29
Extracelluar Matrix Molecules
CHAPTER 30
Cellular Adhesion
CHAPTER 31
Intercellular Junctions
CHAPTER 32
Connective Tissues
SECTION IX: Cytoskeleton and Cellular Motility
CHAPTER 33
Actin and Actin-Binding Proteins
CHAPTER 34
Microtubules and Centrosomes
CHAPTER 35
Intermediate Filaments
CHAPTER 36
Motor Proteins
CHAPTER 37
Intracellular Motility
CHAPTER 38
Cellular Motility
CHAPTER 39
Muscles
SECTION X: Cell Cycle
CHAPTER 40
Introduction to the Cell Cycle
CHAPTER 41
G1 Phase and Regulation of Cell Proliferation
CHAPTER 42
S Phase and DNA Replication
CHAPTER 43
G2 Phase and Control of Entry into Mitosis
CHAPTER 44
Mitosis and Cytokinesis
CHAPTER 45
Meiosis
CHAPTER 46
Programmed Cell Death
Glossary
Index
- Edition: 2
- Published: November 7, 2013
- Language: English
TP
Thomas D. Pollard
Thomas Dean Pollard is a prominent educator, cell biologist and biophysicist whose research focuses on understanding cell motility through the study of actin filaments and myosin motors. He is Sterling Professor of Molecular, Cellular & Developmental Biology and a Professor of Cell Biology and Molecular Biophysics & Biochemistry at Yale University. He was Dean of Yale's Graduate School of Arts and Sciences from 2010 to 2014, and President of the Salk Institute for Biological Studies from 1996 to 2001. Pollard is very active in promoting scientific education and research primarily through two major societies, both of which he is a past President: the American Society for Cell Biology and the Biophysical Society
Affiliations and expertise
Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USAWE
William C. Earnshaw
William Charles Earnshaw is Professor of Chromosome Dynamics at the University of Edinburgh where he has been a Wellcome Trust Principal Research Fellow since 1996. Earnshaw is an elected Fellow of the Royal Society since 2013 for his studies of mitotic chromosome structure and segregation. Before Edinburgh, he was Professor of Cell Biology and Anatomy at Johns Hopkins School of Medicine.
Affiliations and expertise
Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, UKJL
Jennifer Lippincott-Schwartz
Jennifer Lippincott-Swartz is Group Leader at the Howard Hughes Medical Institute Janelia Research Campus. Her lab uses live cell imaging approaches to analyze the spatio-temporal behaviour and dynamic interactions of molecules in cells with a special focus on neurobiology. Before Janelia, Lippincott-Swartz was a primary investigator and chief of the Section on Organelle Biology in the Cell Biology and Metabolism Branch. Her work there included a collaboration with physicists Eric Betzig and Harald Hess (now group leaders at Janelia), who proposed a new function for the photoactivatable protein. The scientists used the protein to generate photoactivatable fluorophores, or dyes, which enabled them to illuminate different sets of molecules sequentially, creating a microscope image far more detailed than previously possible. The method, called super-resolution microscopy, garnered Betzig the 2014 Nobel Prize in Chemistry.
Affiliations and expertise
Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, USA