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Elsevier

Camptothecin and Camptothecin Producing Plants

Botany, Chemistry, Anticancer Activity and Biotechnology

  • 1st Edition - June 18, 2020
  • Latest edition
  • Authors: T. Pullaiah, P.B. Raghavendra, S. Karuppusamy, V. Raveendran, M. Anuradha
  • Language: English

Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemic… Read more

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Description

Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment.

Key features

  • Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments
  • Discusses new applications of camptothecin based on recent biotechnology advancements
  • Presents comprehensive information on the pharmacology of camptothecin for leveraging new anticancer drugs developments

Readership

Cancer researchers, bioinformaticians, molecular biologists, medicinal chemists, pharmacists

Table of contents

1. Cancer biology and other disorders: beneficial role of camptothecin and novel derivativesP.B. Raghavendra2. Camptothecin: chemistry, biosynthesis, analogs, and chemical synthesisT. Pullaiah and V. Raveendran3. Camptothecin and analogs: role in anticancer activitiesP.B. Raghavendra4. Botany of camptothecin-yielding plantsS. Karuppusamy5. Propagation of camptothecin biosynthesizing plantsT. Pullaiah and M. Anuradha6. In vitro camptothecin production from plants: prospects and challengesM. Anuradha, Umalatha, B.K. Indu, S. Balasubramanya and T. Pullaiah7. Biomining of camptothecin producing plants through molecular techniquesS. Karuppusamy8. Endophytes and camptothecin productionT. Pullaiah and M. Anuradha

Product details

  • Edition: 1
  • Latest edition
  • Published: June 19, 2020
  • Language: English

About the authors

TP

T. Pullaiah

T. Pullaiah earned his PhD from Andhra University and then pursued a postdoctoral fellowship at Moscow State University (1976–1978). He is a former Professor of Botany at Sri Krishnadevaraya University, where he taught for more than 35 years. He served as president of the Indian Botanical Society in 2014 and of the Indian Association for Angiosperm Taxonomy in 2013. His honors include the Panchanan Maheshwari Gold Medal, the Prof. P. C. Trivedi Medal, the Dr. G. Panigrahi Memorial Lecture Award of the Indian Botanical Society, and the Prof. Y. D. Tyagi Gold Medal of IAAT. A prolific author and editor, Prof. Pullaiah has mentored students throughout his career and, for several years, has also been a member of the IUCN Species Survival Commission, a global network of over 10,000 volunteer experts dedicated to conserving biodiversity and preventing species extinction through science-based action and collaboration.

Affiliations and expertise
(Retired) Professor, Department of Botany, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India

PR

P.B. Raghavendra

Dr. P.B. Raghavendra is currently affiliated with School of Regenerative Medicine, Manipal University, Bangalore, India, and has served as Director of School of Chemical and Biological Sciences, REVA University. He is the author of Book Advances in Cell and Molecular Diagnostics and a number of articles and book chapters on various aspects of medical sciences and life sciences published in International journals. He is a visiting professor and technology consultant for many universities and biotechnology companies.
Affiliations and expertise
School of Regenerative Medicine, Manipal University, Bangalore, India

SK

S. Karuppusamy

Dr. S. Karuppusamy is currently affiliated with the Department of Botany, The Madura college, Madurai, India. He was Post Doctoral Fellow at Sri Krishnadevaraya University. He has published 10 books and 120 research papers. He was awarded Prof. Y.S.Murthy Gold Medal from Indian Botanical Society.
Affiliations and expertise
Department of Botany, The Madura College, Madurai, India

VR

V. Raveendran

Dr. V. Raveendran is working as Associate Scientist, Cardiovascular Research Program, King Faisal Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia. He was a Post-Doctoral fellow at Department of Internal Medicine, University of Kansas Medical Center, Kansas, USA.
Affiliations and expertise
Associate Scientist, Department of Cell Biology, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia

MA

M. Anuradha

Dr. Maniyam Anuradha is a distinguished academic and innovator in the fields of nutraceuticals and functional food development. With over 30 years of experience spanning research, industry, and education, she currently serves as Principal and Director of R&D at Padmashree Institute of Management and Sciences, Bengaluru. Her extensive work in plant bioactives, nutritional enhancement, and food processing technologies has led to multiple patents and government-funded projects. A former senior scientist at Dr. Reddy’s Laboratories and Sami Labs Ltd., Dr. Anuradha has also pioneered academic programs in nutraceutical and food processing sciences in India. Her contributions have bridged the gap between laboratory innovation and real-world food solutions, making her a recognized leader in the integration of biotechnology and food science.

Affiliations and expertise
Padmashree Institute of Management and Sciences, Bengaluru, India

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