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Bone Remodeling Process
Mechanics, Biology, and Numerical Modeling
- 1st Edition - August 14, 2021
- Authors: Rabeb Ben Kahla, Abdelwahed Barkaoui
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 8 4 6 7 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 2 0 5 - 2
Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condit… Read more
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Request a sales quoteBone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.
This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.
This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.
- Each chapter covers a core topic in bone biomechanics
- Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation
- Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process
Mechanical and biomechanical engineers working on orthopaedics and regenerative medicine. Computational engineers working on finite element method in bone biomechanics and mechanobiology. Researchers in the field of bone biomechanics and mechanobiology. Researchers working on bone biology and quality assessment. Clinicians and industrial pharmacists enhancing and developing drugs and therapeutic procedures. PhD students working on bone biology and/or bone biomechanics
- Cover image
- Title page
- Table of Contents
- Copyright
- Introduction
- Chapter 1. Bone multiscale mechanics
- Abstract
- Abbreviations
- 1.1 Bone multiscale and hierarchical organization
- 1.2 Cortical bone macromechanical properties
- 1.3 Bones as a composite structure
- 1.4 Concluding remarks
- References
- Chapter 2. Bone remodeling biology
- Abstract
- Abbreviations
- 2.1 Bone cells
- 2.2 Bone remodeling cycle
- 2.3 Bone cell interactions
- 2.4 Factors influencing bone from a biological point of view
- 2.5 Concluding remarks
- References
- Chapter 3. Bone diseases and associated therapeutic solutions
- Abstract
- Abbreviations
- 3.1 Metabolic bone diseases
- 3.2 Multiple myeloma
- 3.3 Recent rare case reports
- 3.4 Concluding remarks
- References
- Chapter 4. Bone remodeling mathematical models
- Abstract
- Abbreviations
- 4.1 Bone remodeling in vitro
- 4.2 Mathematical modeling in bone remodeling
- 4.3 Modeling of bone remodeling during treatments
- 4.4 Conclusion and remarks
- References
- Chapter 5. Bone and bone remodeling finite element modeling
- Abstract
- Abbreviations
- 5.1 Finite element modeling healthy bone
- 5.2 Finite element modeling of pathologic bone
- 5.3 Finite element method improvement and validation studies
- 5.4 Finite element modeling of bone remodeling
- 5.5 Concluding remarks
- References
- Chapter 6. Bone remodeling: analysis, discussion, and perspectives
- Abstract
- Abbreviations
- 6.1 Analysis and discussion of the current state
- 6.2 Toward a bone diseases modeling via bone remodeling
- 6.3 Conclusion remarks
- References
- Conclusion
- Index
- No. of pages: 236
- Language: English
- Edition: 1
- Published: August 14, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780323884679
- eBook ISBN: 9780323902052
RB
Rabeb Ben Kahla
Rabeb BEN KAHLA is a Mechanical Engineering PhD student at the National Engineering School of Tunis, Tunisia. She conducts research at LASMAP (Research Laboratory of Systems and Applied Mechanics) of Tunisia Polytechnic School. Currently assistant teacher at Ecole d'Ingénieurs Généraliste du Numérique (Efrei PARIS), France, she is the author of the book “Finite element method and medical imaging techniques in bone biomechanics” (Wiley ISBN: 978-1-786-30518-3) and three publications in well-known journals in the field of biomechanics (Journal of the Mechanical Behavior of Biomedical Materials, Biomechanics and Modeling in Mechanobiology , Journal of Mechanics in Medicine and Biology).
Affiliations and expertise
Researcher, LASMAP (Research Laboratory of Systems and Applied Mechanics), Tunisia Polytechnic School, TunisiaAB
Abdelwahed Barkaoui
Abdelwahed Barkaoui is a Full Professor of Mechanical Engineering at the International University of Rabat, Morocco. He is currently the head of the Mechanical and Advanced Materials Division at the LERMA Laboratory and the coordinator of the Biomechanics and Mechanobiology Research Team (MeV). Additionally, he is responsible for the international accreditation at the College of Engineering and Architecture. His research primarily focuses on problems in biomechanics, mechanobiology, and biomedical engineering.
Affiliations and expertise
Full Professor, Mechanical Engineering, International University of Rabat, Morocco; Head of the Mechanical and Advanced Materials Division at the LERMA Laboratory; Coordinator of the Biomechanics and Mechanobiology Research Team (MeV)Read Bone Remodeling Process on ScienceDirect