Biothermodynamics Part A
- 1st Edition, Volume 455 - March 14, 2009
- Imprint: Academic Press
- Editors: Michael L. Johnson, Jo M. Holt, Gary K. Ackers
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 7 4 5 9 6 - 5
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 9 2 3 4 0 - 6
In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This… Read more
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In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an “energy book-keeping system.” While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.
Researchers in academics and industry studying biochemistry.
- Edition: 1
- Volume: 455
- Published: March 14, 2009
- Imprint: Academic Press
- Language: English
MJ
Michael L. Johnson
Affiliations and expertise
University of Virginia Health Sciences Center, Charlottesville, USAJH
Jo M. Holt
Affiliations and expertise
Washington University Medical Center, St. Louis, MO, USAGA
Gary K. Ackers
Affiliations and expertise
Washington University School of Medicine, St. Louis, Mo, USARead Biothermodynamics Part A on ScienceDirect