Bioprospecting of Microbial Diversity

Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection

1st Edition - February 1, 2022
Editors: Pradeep Verma, Maulin P. Shah
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 9 5 8 - 7
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 5 7 5 - 1

Bioprospecting of Microbial Diversity: Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection gives a detailed insight into the utilizati… Read more

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Bioprospecting of Microbial Diversity: Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection gives a detailed insight into the utilization of microorganisms or microorganism-based bioactive compounds for the development of sustainable approaches, covering recent advances and challenges in the production and recovery of bioactive compounds such as enzymes, biopesticides, biofertilizers, biosensors, therapeutics, nutraceutical and pharmaceutical products. The challenges associated with the different approaches of microbial bioprospecting along with possible solutions to overcome these limitations are addressed. Further, the application of microbe-based products in the area of environmental pollution control and developing greener technologies are discussed. Providing valuable insight into the basics of microbial prospecting, the book covers established knowledge as well as genomic-based technological advancements to offer a better understanding of its application to various industries, promoting the commercialization of microbial-derived bioactive compounds and their application in biochemical industries, agriculture, and environmental protection studies.

Cover image
Title page
Table of Contents
Copyright
Contributors
About the editors
Preface
Acknowledgment
Chapter 1: Role of bioinformatics tools in microbial prospectives and its future
Abstract
1.1: Introduction
1.2: Overview of the role of bioinformatics in microbiology
1.3: Prokaryotic genome sequencing
1.4: Prokaryotic genome annotation
1.5: Microbial profiling
1.6: Metagenomics and microbiome
1.7: Analysis of the human microbiome with the 16s rRNA gene
1.8: Phylogenetic microchips
1.9: Bacterial genetic barcode and their uses
1.10: NGS in microbial metabolism
1.11: The role of genomics in finding microbes
1.12: Genome scale metabolic reconstruction
1.13: Summary
Chapter 2: Recent trends in genomic approaches for microbial bioprospecting
Abstract
2.1: Introduction
2.2: Overall scheme for genome-based bioprospecting
2.3: Culture-independent methods
2.4: Bioprospecting through RT-PCR
2.5: Heterologous expression of secondary metabolite biosynthesis gene
2.6: DNA microarrays
2.7: PCR-independent amplification techniques
2.8: Shift to metagenomic approach
2.9: Synthetic biology approaches to hetero-expression of new gene clusters
2.10: Conclusion
Chapter 3: Revolution in microbial bioprospecting via the development of omics-based technologies
Abstract
3.1: Introduction
3.2: Loopholes in microbial cultivation and emergence of culture-independent methods
3.3: Development of “omics-based” approaches for microbial cultivation
3.4: Potential applications of “omics” technology in microbial bioprospecting
3.5: Conclusion
Chapter 4: Microbial assisted production of alcohols, acetone and glycerol
Abstract
4.1: Introduction
4.2: Production of acetone, butanol and ethanol through ABE fermentation
4.3: Fermentative production of bio-butanol
4.4: Fermentative production of acetone
4.5: Fermentative production of bio-ethanol
4.6: Fermentative production of bio-glycerol
4.7: Microbial production of bio-methanol
4.8: Conclusion
Chapter 5: Assessing technical and commercial aspects of soil microbiome in growing leguminous plants and formation of bio-fertilizer
Abstract
5.1: Introduction
5.2: Microbial ecosystem in soil
5.3: Significance of microbiome in soil fertility management
5.4: Symbiotic interaction with plants
5.5: Green manure as bio-fertilizer
5.6: Leguminous crops as bio-fertilizer
5.7: Commercial aspects of bio-fertilizer
5.8: Conclusion
Chapter 6: Mechanisms of multifarious soil microbial enzymes in plant growth promotion and environmental sustainability
Abstract
6.1: Introduction
6.2: Microbial enzymatic indexes
6.3: Mechanisms of action of microbial enzymes
6.4: Factors affecting microbial enzyme activities
6.5: Microbial enzymes as potential indicators of soil contamination
6.6: Conclusions and future prospects
Chapter 7: Bioprospecting of endophytes: Recent advances in endophytic microbes for industrially important bioactive compounds
Abstract
7.1: Introduction
7.2: Current scenario of endophytic bacteria
7.3: Current scenario of endophytic fungi
7.4: Conclusion and future prospects
Conflicts of interest
Chapter 8: MnP enzyme: Structure, mechanisms, distributions and its ample opportunities in biotechnological application
Abstract
Acknowledgment
8.1: Introduction and structure
8.2: Catalytic mechanisms of MnP enzyme
8.3: Distribution in fungi and bacteria
8.4: Physicochemical and molecular properties of MnP
8.5: Effects of various environmental and nutritional parameters on enzyme activity
8.6: Decomposition and action of mechanisms
8.7: Ample opportunities in biotechnological application
8.8: Conclusion
Chapter 9: Microbes and their products as novel therapeutics in medical applications
Abstract
9.1: Introduction
9.2: Prophylactic and therapeutic vaccines
9.3: Virotherapy
9.4: Microbes as source of antibiotics
9.5: Clinical applications of microbial enzymes
9.6: Bacterial therapeutic products
9.7: Medical applications of fungi
9.8: Conclusion
9.9: Summary
Chapter 10: Bioprospecting potential of microbes for the therapeutic application
Abstract
10.1: Introduction
10.2: Microbial synthesized biologics
10.3: Microorganism: A potential source of bioactive compounds
10.4: Upgradation of microorganisms and synthesis of new analogs
10.5: Future prospects of microbial biologics and conclusion
Chapter 11: Microbial bioprospecting in development of integrated biomass based biorefineries
Abstract
11.1: Introduction
11.2: Biorefinery concept in bioprocess industries
11.3: Screening and identification methods of potential microbes
11.4: Biotechnology in bioprospecting of microbes
11.5: Case studies of successful biorefineries
11.6: Future prospects
11.7: Conclusion
Chapter 12: Microbial bioprospecting for biorefinery application: Bottlenecks and sustainability
Abstract
12.1: Introduction
12.2: Microbial bioprospecting
12.3: Biorefinery
12.4: Bioconversion routes
12.5: Sustainability aspects of microbial bioprospecting for biorefinery
12.6: Challenges of microbial biorefinery applications
12.7: Conclusion
Chapter 13: Bioelectricity recovery from food waste using microbial fuel cell: Recent advances
Abstract
Practical application
13.1: Introduction
13.2: Traditional method for generation of bioelectricity from waster
13.3: Food waste generation in the globe and its energy analysis
13.4: Limitation of conventional food waste management technologies
13.5: Microbial fuel cell—For simultaneous wastewater treatment and bioelectricity production
13.6: Bioelectricity generation from food waste: Food sources as substrates for MFC
13.7: Factors affecting the performance of MFC utilizing food waste
13.8: Strategy to enhance the efficiency of MFC performance
13.9: Techno-economic evaluation of microbial fuel cell
13.10: MFC commercialization
13.11: Challenges and limitation in MFC operation
13.12: Perspective and conclusion
Chapter 14: Bioprospecting of microalgae derived high value compounds with commercial significance
Abstract
14.1: Introduction
14.2: Microalgae: Rich source of high-value compounds
14.3: Pigments from microalgae
14.4: Source of proteins and amino acids
14.5: Functional carbohydrates
14.6: Essential fatty acids
14.7: Vitamins and minerals
14.8: Current and projected global market
14.9: Regulatory compliance
14.10: Challenges and limitations
14.11: Conclusion and future considerations
Chapter 15: Microbial bioprospecting for nutraceuticals and value-added compounds
Abstract
15.1: Introduction
15.2: Concept of nutraceuticals
15.3: Classification
15.4: Health benefits
15.5: Need for microbial production of nutraceuticals
15.6: Microbes and nutraceuticals
15.7: Developments in delivery systems
15.8: Microbiome for delivery of nutraceuticals
15.9: Relevance and challenges of commercial production
15.10: Conclusion/summary
Chapter 16: Biofilm interceded microbial prospecting of bioremediation
Abstract
16.1: Introduction
16.2: Bioremediation
16.3: Role of biofilms in bioremediation
16.4: Strategies for use of biofilms in remediation
16.5: Bioremediation of various pollutants by biofilm
16.6: Assessment of various methods of biofilm interceded bioremediation
16.7: Future perspectives for bioremediation
16.8: Summary
Chapter 17: Microbial-based eco-friendly processes for the recovery of metals from E-waste
Abstract
17.1: Introduction
17.2: Composition of E-waste
17.3: Biotechnological approach for the recovery of metals from E-waste
17.4: Future R&D
17.5: Conclusion
Chapter 18: Evaluation of environment by microbial sensors
Abstract
18.1: Introduction of microbial sensor
18.2: Main components of a biosensor
18.3: Working principle of a biosensor
18.4: Types of biosensors
18.5: Other sensor systems
18.6: Implications of biosensor frameworks in the natural evaluation
18.7: Applications of biosensor frameworks in the natural evaluation
18.8: Pros and thorns of biosensor systems
18.9: Future viewpoints of microbial sensors in ecological assessment
18.10: Summary
Chapter 19: Insight into microbial biosensors: Design, types and applications
Abstract
19.1: Introduction
19.2: Advantages of microbial biosensors
19.3: Design of microbial biosensors
19.4: Types of microbial biosensors based on types of sensing mechanism
19.5: Applications of microbial sensors in different areas
19.6: Conclusion
Chapter 20: New strategies in microbial screening for novel chemotherapeutics
Abstract
20.1: Introduction
20.2: Conventional chemotherapeutics and their limitations
20.3: Microbial extracts as novel chemotherapeutics
20.4: New strategies for screening microbes to isolate chemotherapeutic metabolites
20.5: Future perspectives and conclusions
Conflict of interest
Chapter 21: Seaweeds as potential source of bioactive compounds with special emphasis on bioprospecting in COVID-19 situation
Abstract
21.1: Introduction
21.2: Current treatment scenario for COVID-19
21.3: Bioactive antiviral compounds from seaweeds
21.4: Bioactive compounds from seaweeds with a beneficial role in general human health and immunity
21.5: Bioactive compounds from seaweeds controlling secondary infections
21.6: Potential role of seaweed-derived bioactive compounds as a therapeutic agent in COVID-19 disease management
21.7: Conclusion
Chapter 22: Bioprospecting of extremophiles for industrial enzymes
Abstract
22.1: Introduction
22.2: Extremozymes and their industrial significance
22.3: Extremozymes from thermophiles
22.4: Extremozymes from psychrophiles
22.5: Conclusion and future challenges
Competing interests
Chapter 23: Bioenergy: An overview of bioenergy as a sustainable and renewable source of energy
Abstract
23.1: Introduction
23.2: Bioethanol
23.3: Biodiesel
23.4: Biogas and biohydrogen
23.5: Advance bioenergy
23.6: Challenges
23.7: Conclusion
Chapter 24: Microbial diversity and bioprospecting potential of Phragmites rhizosphere microbiome through genomic approaches
Abstract
Acknowledgment
24.1: Introduction
24.2: Structure and function of Phragmites microbiome
24.3: P. karka rhizosphere microbiome: An unexplored niche for bioprospecting
24.4: Conclusions and perspectives
Index

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Pradeep Verma

Maulin P. Shah