Bionanocatalysis: From Design to Applications

1st Edition - August 22, 2023
Editors: Roberto Fernandez-Lafuente, Muhammad Bilal, Hafiz M.N. Iqbal, Tuan Anh Nguyen
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 7 6 0 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 6 4 2 - 7

Bionanocatalysis: From Design to Applications discusses recent advances in nano-biocatalysis, fundamental design concepts and their applications in a variety of industry sectors.… Read more

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Bionanocatalysis: From Design to Applications discusses recent advances in nano-biocatalysis, fundamental design concepts and their applications in a variety of industry sectors. Strategies for immobilizing enzymes onto nanocarriers, made from polymers, silicas, carbons, and metals, by physical adsorption, covalent binding, cross-linking, or specific ligand spacers are also discussed as are the advantages, problems and solutions derived from the use of non-porous nanomaterials for enzyme immobilization. This is an important reference source for materials scientists and chemical engineers who would like to learn more about how nanobiocatalysts are designed and used.

Biocatalysis has emerged as a sustainable technique to synthesize valuable commodity chemicals with wide applications in various industrial domains, such as in agriculture, cosmetics, pharmaceuticals, biofuels, biosensors, biofuel cells, biochemicals, and foods. The synergistic integration of bio-catalysis engineering with nanostructured materials, as unique multifunctional carrier matrices, has emerged as a new interface of nano-biocatalysis (NBC).

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Part 1. Basic principles
Chapter 1. Nanobiocatalysis: A drive towards applied biocatalysis
1. Introduction
2. Nanomaterials involved in development of nanobiocatalysts
3. Chemistry involved in immobilization of enzymes on nanomaterials
4. Applications of nanobiocatalysts in different fields of life
5. Recycling of nanobiocatalyst
6. Conclusion and future perspectives
Chapter 2. Bi- or multienzymatic nanobiocatalytic systems
1. Introduction
2. Multienzyme immobilization technologies
3. Support materials for multienzyme immobilization
4. Conclusion
Chapter 3. Mechanism of structural and functional coordination between enzymes and nonstructural cues
1. Introduction
2. Properties of immobilized enzymes
3. Nanomaterials-based advantages in enzyme immobilization
4. Nanomaterials-based disadvantages in enzyme immobilization
5. Structural coordination between enzyme and nonstructural cues
6. Strategies for functionalization of nanomaterials
7. Development of nanobiocatalysts by nonstructured materials
8. Concluding remarks
Chapter 4. Engineering enzyme for microenvironment
1. Introduction
2. Protein engineering drives biocatalysis
3. Dynamic activity of enzymes
4. Create a wetland environment
5. Conclusion and future standing points
Chapter 5. Thermal tuning of enzyme activity by magnetic heating
1. The concept
2. Principles
3. Examples of enzyme tuning by magnetic heating
4. Challenges for an industrial application
5. Application examples of saptiotemporal control to target unmeet challenges of multienzymatic cascade reactions
6. Final remarks
7. Funding
Part 2. Prospective nanocarriers to design nano-biocatalysts
Chapter 6. Carbon dots–based photocatalyst: Synthesis, characteristic attributes, mechanisms, and applications
1. Introduction
2. Synthesis methods
3. Application of carbon dots in photocatalysis
4. Current challenges and recommendations
5. Conclusions
Chapter 7. Silica-based nanocarriers
1. Introduction
2. Surface functionalization
3. Synthesis of mesoporous silica nanocarriers
4. Application of silica-based nanocarriers
5. Conclusion
Chapter 8. Use of magnetic nanoparticles to build magnetic macroporous biocatalyst: Prospects and trends
1. Introduction
2. Production of ex novo macrobiocatalysts to solve the problems of nanomaterials handling
3. Magnetic macrobiocatalyst to facilitate the handling and recovery of biocatalysts with low mechanical resistance
4. Recovery and reuse of immobilized enzyme biocatalysts from suspensions containing the substrates and/or the final products
5. Reuse of the most stable immobilized enzyme biocatalyst when combining several ones in one-pot multienzymatic processes
6. Use of hyperthermia generated by paramagnetic nanoparticles to modulate the enzyme features
7. Generation of (magnetic) heterosurface functionality supports
8. Conclusions and future trends
Part 3. Emerging bioprocessing applications
Chapter 9. Implementation of nanobiocatalysis in food industry
1. Introduction
2. Enzyme immobilization and its benefits
3. Nanomaterials for the development of nanobiocatalysts
4. Uses of nanobiocatalysts in food industry
5. Assessing the risks of nanomaterials in the food industry
6. Conclusion and future trends
Chapter 10. Nanobiocatalysis for food and feed application
1. Introduction
2. Biocompatible nanomaterials in the food industry
3. Nanotechnologies in the food industry
4. Application of nanomaterials in various sectors of the food industry
5. Conclusion
Chapter 11. Nanobiocatalysis for environmental remediation and protection
1. Introduction
2. Different types of environmental pollutants
3. Nanobiocatalysis—synthesis and characterization
4. Types of nanoparticles and their characterization methods
5. Mechanisms behind enhanced activities of nanobiocatalysts
6. Role of nanobiocatalysis for remediation of environmental pollutants
7. Limitations of nanobiocatalysis in environmental remediation
8. Conclusion and future perspective
Chapter 12. Nanobiocatalysis for therapeutic applications
1. Introduction
2. Therapeutic applications of nanozymes
3. Conclusion
Chapter 13. Nanobiocatalysts for drug delivery
1. Introduction
2. Enzyme-responsive nanomaterials
3. Hydrolase-responsive materials
4. Conclusion and future perspective
Chapter 14. Nanobiocatalysis for biofuel production
1. Introduction
2. From fossil fuels to biofuels
3. Substrates for biofuel production
4. Different generations of biofuels
5. Methods for biofuel production
6. Thermochemical pathway
7. Biochemical pathway
8. The need for nanobiocatalysis
9. The role of nanobiocatalysis in enzyme immobilization
10. Process of nanobiocatalysis
11. Development of nanoparticles for biofuel production
12. Potential applications of nanobiocatalysis in biofuel production
13. Nanobiocatalysis in biodiesel production
14. Nanobiocatalysis in bioethanol production
15. Nanobiocatalysis in biohydrogen production
16. Nanobiocatalysis in biogas production
17. Challenges and limitations
18. Conclusion
Chapter 15. Nanobiocatalysis for pharmacological and therapeutic applications
1. Introduction
2. Status of nanobiocatalysis in pharmaceutical industries and their related applications
3. Nanoparticle-based therapeutics in preclinical development
4. Nanobiocatalysis-based therapeutics permitted for clinical use
5. Nanoparticle-based therapeutics in clinical trials
6. Conclusions and prospects
Chapter 16. Self-assembly of small molecules for enzyme mimicry
1. Introduction
2. DNA-based self-assembly
3. Conclusion
Chapter 17. Nanostructured biocatalysis for biotechnological applications
1. Introduction
2. Synthesis of nanostructures and nanomaterials
3. Assembly of nanoparticles
4. Immobilization strategies of different components
5. Nanomaterials for immobilization of enzymes
6. Methods for enzyme immobilization
7. Biotechnological applications of immobilized enzymes
8. Challenges and future perspectives
9. Conclusion
Chapter 18. Immobilization of enzymes on nanomaterials: necessity, opportunities, and drawbacks
1. Introduction
2. Nanomaterials for enzyme immobilization: when they become the only alternative
3. Considerations to prepare a nanobiocatalyst to be used versus a very large or a solid substrate
4. Possibilities of getting an intense multipoint or multisubunit enzyme immobilization
5. Distribution of enzymes on the support surface: porous versus nonporous supports
6. Interactions between immobilized enzymes and external surfaces or structures
7. Handling of nanoparticles: nanoparticles of nanobiocatalyst aggregation
8. Handling of nanoparticles: reactor options
9. Possibility to increase enzyme loading: formation of multilayers
10. Advantages of coimmobilized enzymes: what if the support is a nonporous one?
11. Nanoparticles preparation for biocatalysis design
12. Conclusions and future trends
Chapter 19. Environmental remediation and protection
1. Introduction
2. Remediation strategies for polluted environments
3. Environmental pollution and biological treatments
4. Bioremediation and its types
5. Enzyme used in bioremediation
6. Nanoenzymes for the detection of environmental pollutants
7. Nanoenzymes in environmental treatment
8. Methods for removing organic pollutants from water
9. Management of air pollution
10. Role of nanoenzymes in the monitoring of soil pollution and their restoration
11. Enzymatic biosensors monitor pollutants
12. Conclusions
13. Summary
Chapter 20. Biofuel cells
1. Introduction
2. Battery versus fuel cell
3. Historical perspective of fuel cell technology
4. Classification of fuel cells
5. Biofuel cells
6. Biofuel cells—motivation, goals, and applications
7. Conclusion
Chapter 21. Extending the reach of computational approaches to model enzyme catalysis
1. Chemistry and catalyst
2. Biochemistry, biocatalyst, and catalyst
3. Regio- and enantioselectivity
4. Methods and theoretical background
5. Molecular mechanical simulations
6. Conclusion
Chapter 22. Sugar-processing microbial enzymes
1. Introduction
2. Major types of sugar-processing microbial enzymes
3. Applications of various α-amylases
4. Microbial enzymes having vast applications in biotechnology
5. Improvement in enzymes
6. Future perspective
7. Conclusion
Index

Roberto Fernandez-Lafuente

Professor Roberto Fernandez-Lafuente is Research professor at the Institute of Catalysis and Petrochemistry, Madrid, Spain. Hi areas of research are the esign of biocatalysts and biosensors, biomacromolecules immobilization, enzyme stabilization, protein purification, and bioprocess design.

Affiliations and expertise

Research Professor, Institute of Catalysis and Petrochemistry, Madrid, Spain

Muhammad Bilal

Muhammad Bilal is an associate professor at the Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdańsk University of Technology, Gdańsk, Poland. He has published more than 350 research papers in leading international journals and also serves as an Associate Editor for several of these journals.

Affiliations and expertise

Associate Professor, Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdańsk University of Technology, Gdańsk, Poland

Hafiz M.N. Iqbal

Dr. Hafiz M.N. Iqbal is a Professor at the School of Engineering and Sciences, Tecnologico de Monterrey, Mexico. He completed his Ph.D. in Biomedical Sciences with a specialization in Applied Biotechnology and Materials Science at the University of Westminster, London, UK. Dr. Iqbal’s research group is engaged in Environmental Engineering, Bioengineering, Biomedical Engineering, Materials Science, Enzyme Engineering, Bio-catalysis, Bioremediation, Algal Biotechnology, and Applied Biotechnology related research activities. With more than 11,400 citations, Dr. Iqbal has guest-edited several special issues and served as an Editorial Board member for several peer-reviewed journals. Dr. Iqbal has published more than 400 scientific contributions in the form of research, reviews, book chapters, and editorials, at several platforms in various journals of national/international repute with high impact factors.

Affiliations and expertise

Professor, School of Engineering and Sciences, Tecnologico de Monterrey, Mexico

Tuan Anh Nguyen

Tuan Anh Nguyen is Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. His research focuses on advanced nanomaterials and nanotechnology for corrosion and materials integrity in transportation systems. His research activities include smart coatings, conducting polymers, corrosion and protection of metals/concrete, antibacterial materials, and advanced nanomaterials.

Affiliations and expertise

Senior Principal Research Scientist, Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam

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Bionanocatalysis: From Design to Applications

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Roberto Fernandez-Lafuente

Muhammad Bilal

Hafiz M.N. Iqbal

Tuan Anh Nguyen