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Biomedical Information Technology

The enormous growth in the field of biotechnology necessitates the utilization of information technology for the management, flow and organization of data. The field continues to… Read more

Description

The enormous growth in the field of biotechnology necessitates the utilization of information technology for the management, flow and organization of data. The field continues to evolve with the development of new applications to fit the needs of the biomedicine. From molecular imaging to healthcare knowledge management, the storage, access and analysis of data contributes significantly to biomedical research and practice.

All biomedical professionals can benefit from a greater understanding of how data can be efficiently managed and utilized through data compression, modelling, processing, registration, visualization, communication, and large-scale biological computing. In addition Biomedical Information Technology contains practical integrated clinical applications for disease detection, diagnosis, surgery, therapy, and biomedical knowledge discovery, including the latest advances in the field, such as ubiquitous M-Health systems and molecular imaging applications.

Key features

  • The world's most recognized authorities give their "best practices" ready for implementation
  • Provides professionals with the most up to date and mission critical tools to evaluate the latest advances in the field and current integrated clinical applications
  • Gives new staff the technological fundamentals and updates experienced professionals with the latest practical integrated clinical applications

Readership

biomedical and clinical engineers; physicians and surgeons; health physicists; bioinformaticists; biomedical researchers, students, educators; members of the basic science community; IT specialists, healthcare professionals and researchers.

Table of contents

Section I: Technological Fundamentals

Chapter 1 Medical Imaging
Dr. Xiaofeng Zhang, Dr. Nadine Smith and Prof. Andrew Webb


1.1 Introduction

1.2 Digital radiography

1.3 Computed tomography

1.4 Nuclear medicine

1.5 Ultrasonic imaging

1.6 Magnetic resonance imaging

1.7 Diffuse optical imaging

1.8 Biosignals

1.9 Appendix

1.10 Exercises

1.11 Bibliography

1.12 Index

Chapter 2 Electronic Medical Record (EMR)

Dr. Eugene,Y. S. Lim, Prof. Michael Fulham and Prof. David Dagan Feng


2.1 Introduction

2.2 Medical data and patient record

2.3 Terminology standards – vocabulary and a clinical coding system1

2.4 Information exchange standards

2.5 Usability issues in EMR

2.6 User interface

2.7 Evaluation

2.8 EMR system – a case study: a web-based imaging electronic patient history

2.9 Summary

2.10 Exercise

2.11 Bibliography and references

2.12 Index

Chapter 3 Image Data Compression and Storage

Prof. Hong Ren Wu, Dr. Damian M. Tan, Dr. Tom Weidong Cai and Prof. David Dagan Feng


3.1 Introduction

3.2 Picture compression

3.3 Compression in the dicom standard

3.4 Data compression for dynamic functional images

3.5 Summary

3.6 Exercises

3.7 References

3.8 Index


Chapter 4 Content-Based Medical Image Retrieval

Dr. Tom Weidong Cai, Dr. Jinman Kim and Prof. David Dagan Feng


4.1 Introduction

4.2 CBMIR by physical visual features

4.3 CBMIR by geometric spatial features

4.4 CBMIR by combination of semantic and visual features

4.5 CBMIR by physiological functional features

4.6 Summary

4.7 Exercises

4.8 Bibliography and references

4.9 Index

Chapter 5 Data Modeling and Simulation

Dr. Alessandra Bertoldo, Prof. Claudio Cobelli


5.1 Introduction

5.2 Compartmental models

5.3 Model identification

5.4 Model validation

5.5 Simulation

5.6 Case study

5.7 Quantification of medical images

5.8 Exercises

5.9 Bibliography and references

Chapter 6 Techniques for Parametric Imaging

Prof. David Dagan Feng, Dr. Lingfeng Wen and Dr. Stefan Eberl


6.1 Introduction

6.2 Parametric image estimation methods

6.3 Noninvasive methods

6.4 Clinical applications of parametric images

6.5 Summary

6.6 Exercise

6.7 Bibliography and references

6.8 Index

Chapter 7 Data Processing and Analysis

Prof. Chris Wyatt, Prof. Yu-Ping Wang, Prof. Matthew T. Freedman, Prof. Murray Loew and Prof. Yue Wang


7.1 Introduction

7.2 Medical image enhancement

7.3 Medical image segmentation

7.4 Medical image feature extraction

7.5 Medical image interpretation

7.6 Summary

7.7 Exercises

7.8 Bibliography

7.9 Index

Chapter 8 Data Registration and Fusion

Dr. Xiu Ying Wang, Dr. Stefan Eberl, Prof. Michael Fulham, Dr. Seu Som and Prof. David Dagan Feng



8.1 Introduction

8.2 Fundamentals of biomedical image registration and fusion

8.3 Feature-based medical image registration

8.4 Intensity-based registration

8.5 Hybrid registration and hierarchical registration

8.6 Hardware registration

8.7 Assessment of registration accuracy

8.8 Applications of biomedical image registration and fusion

8.9 Summary

8.10 Exercises

8.11 Bibliography and references

8.12 Index

Chapter 9 Data Visualization and Display
Dr. Jinman Kim, Dr. Tom Weidong Cai, Prof. Michael Fulham, Dr. Stefan Eberl and Prof. David Dagan Feng


9.1 Introduction

9.2 Two-Dimensional (2D) visualization techniques

9.3 Three-Dimensional (3D) visualization techniques

9.4 Volume navigation interface

9.5 Volume enhancement and manipulation

9.6 Large data visualization and optimization

9.7 Dual-modality PET/CT visualization

9.8 Data display devices

9.9 Applications of biomedical visualization

9.10 Summary

9.11 Exercises

9.12 Bibliography and references

9.13 Index

Chapter 10 Data Communication and Network Infrastructue

Prof. Doan B. Hoang and Dr. Andrew J. Simmonds


10.1 Introduction

10.2 Transmission and communication technologies

10.3 The internet and World Wide Web

10.4 Wireless and mobile technologies in m-health

10.5 Sensor networks for health monitoring

10.6 Applications of wireless technologies in telemedicine

10.7 Summary

10.8 Exercises

10.9 Bibliography and references

10.10 Index

Chapter 11 Data Security and Protection for Medical Images

Dr. Eugene, Y. S. Lim


11.1 Introduction

11.2 Overview of cryptographic system

11.3 Digital watermarking

11.4 Medical image watermarking

11.5 Region-based reversible watermarking for secure pet image management

11.6 Summary

11.7 Exercise

11.8 Bibliography

11.8 Index

Chapter 12 Biological Computing

Prof. Eric P Hoffman, Erica Reeves, Dr. Yetrib Hathout, Dr. Zuyi Wang and
Josephine Chen


12.1 Introduction

12.2 Overview of genomic methods

12.3 Overview of proteomic methods

12.4 Bioinformatics and information infrastructure

12.5 Data mining and large-scale biological databases

12.6 Biological event-driven, time-driven and hybrid simulation techniques

12.7 Summary

12.8 Bibliography


Section II: Integrated Applications

Chapter 13 PACS and Medical Imaging Informatics (MII) for Filmless Hospitals


Prof. Brent J. Liu and Prof. H.K. Huang


13.1 Introduction

13.2 PACS infrastructure

13.3 PACS components and workflow

13.4 PACS controller and image archive

13.5 Large-scale PACS implementation

13.6 PACS clinical experiences

13.7 Summary

13.8 Exercises

13.9 Bibliography and references

13.9 Index

Chapter 14 KMeX: A Knowledge-Based Digital Library for Retrieving Scenario-Specific Medical Text Documents
Prof. Wesley W. Chu, Dr. Zhenyu Liu, Dr. Wenlei Mao and Dr. Qinghua Zou


14.1 Introduction

14.2 Extracting key concepts from documents

14.3 Transforming similar queries into query templates

14.4 Topic-oriented directory

14.5 Phrase-based vector space model for automatic document retrieval

14.6 Knowledge-based scenario-specific query expansion

14.7 A system architecture for retrieving scenario-specific free text documents

14.8 Summary

14.9 Exercises

14.10 Bibliography

Chapter 15 Integrated Multimedia Patient Record Systems
Dr. Ruth E. Dayhoff, Mr. Peter M. Kuzmak and Mr. Kevin Meldrum


15.1 Introduction

15.2 Multimedia patient record

15.3 Multimedia patient record system architecture components

15.4 Electronic medical chart components

15.5 Objects comprising the multimedia patient record

15.6 Capturing multimedia data at the source

15.7 DICOM image acquisition

15.8 Remote data and image viewing across the healthcare network

15.9 Impact on patient care

15.10 Summary

15.11 References

Chapter 16 Computer-Aided Diagnosis (CAD)
Prof. Maryellen L. Giger and Dr. Kenji Suzuki


16.1 Introduction

16.2 CAD

16.3 CAD for cancer screening

16.4 CAD for differential diagnosis

16.5 Intelligent CAD workstations – indices of similarity and human/computer interfaces

16.6 Summary

16.7 Exercises

16.8 Bibliography

16.9 Index

Chapter 17 Clinical Decision Support Systems (CDSS)

Dr. Peter Weller, Dr. Abdul Roudsari and Prof. Ewart Carson


17.1 Introduction

17.2 Overview of CDSS

17.3 Human diagnostic reasoning

17.4 A structure for characterising CDSS

17.5 Decision support tools

17.6 Decision support systems in the hospital and other healthcare settings

17.7 Healthcare education applications

17.8 Verification, validation and evaluation

17.9 Summary

17.10 Exercises

17.11 References

17.12 Index

Chapter 18 Medical Robotics and Computer-Integrated Interventional Medicine

Prof. Russell H. Taylor and Dr. Peter Kazanzides


18.1 Introduction

18.2 Technology & Techniques

18.3 Surgical CAD/CAM

18.4 Surgical Assistance

18.5 Summary and conclusion

18.6 Exercises

18.7 References

18.8 Index

Chapter 19 Functional Techniques for Brain Magnetic Resonance Imaging
Dr. Sirong Chen, Dr. Kai-Ming Au Yeung and Dr. Gladys Goh Lo


19.1 Introduction

19.2 Diffusion-weighted MR imaging in brain

19.3 MR perfusion imaging in brain

19.4 Functional MRI (fMRI) using bold techniques

19.5 Clinical MR spectroscopy in brain

19.6 Summary

19.7 Exercises

19.8 Bibliography and references

19.9 Index

Chapter 20 Molecular Imaging in Cancer
Prof. Kristine Glunde, Dr. Catherine A. Foss and Prof. Zaver M. Bhujwalla


20.1 Introduction

20.2 Imaging of gene expression

20.3 Receptor imaging

20.4 Enzyme-activated probes

20.5 Metabolic imaging

20.6 Imaging of permeability, perfusion, and blood flow

20.7 Imaging of the tumor microenvironment

20.8 Multimodality imaging

20.9 Conclusion

20.10 Exercises

20.11 References

20.12 Index

Chapter 21 Molecular Imaging in Biology and Pharmacology
Prof. Sung-Cheng Huang, Prof. Anna M. Wu and Prof. Jorge R. Barrio


21.1 Introduction and background

21.2 Considerations for quantitative molecular imaging

21.3 Design/development of molecular imaging probes

21.4 Molecular imaging of beta-amyloid and NFT

21.5 Molecular imaging using antibody probes

21.6 Some other molecular imaging applications

21.7 Summary and future perspectives

21.8 Exercises

21.9 References

21.10 Index

Chapter 22 From Telemedicine to Ubiquitous M-Health: the Evolution of E Health Systems

Dr. Dejan Raškoviæ, Dr. Aleksandar Milenkoviæ, Prof. Piet C. De Groen and
Dr. Emil Jovanov


22.1 Introduction

22.2 Overview of m-health systems

22.3 M-health based on Wireless Body Area Networks (WBAN)

22.4 Wireless intelligent sensors for m-health

22.5 Wireless mobile devices for m-health

22.6 Next-generation m-health systems

22.7 Summary

22.8 Exercises

22.9 References

22.10 Index

Chapter 23 Multimedia for Future Health – Smart Medical Home………………1

Dr. Jinman Kim, Dr. Zhiyong Wang, Dr. Tom Weidong Cai and Prof. David Dagan Feng


23.1 Introduction

23.2 Multimedia for human-computer interaction

23.3 Multimedia content management

23.4 Multimedia delivery

23.5 Smart medical home

23.6 Telemedicine in the smart medical home

23.7 Sensory devices and health monitoring

23.8 Speech recognition and conversational systems

23.9 Multimedia technologies for patient education and care

23.10 Multimedia operating theater and Virtual Reality (VR)

23.11 Summary

23.12 Exercises

23.13 References

23.15 Index

Product details

About the editor

DF

David Dagan Feng

Professor David Dagan Feng is Founder and Director, Biomedical and Multimedia Information Technology (BMIT) Research Group, Funding Director, Institute of Biomedical Engineering & Technology (BMET), and Funding Head, School of Information Technology (recently renamed as School of Computer Science), the University of Sydney (USYD), as well as Academic Director, USYD-SJTU (Shanghai Jiao Tong University) Joint Research Alliance. He has been, Head of Department of Computer Science and Associate Dean, Faculty of Science, the University of Sydney; Honorary Research Consultant, Royal Prince Alfred Hospital, the largest hospital in Australia; Chair Professor of Information Technology, Hong Kong Polytechnic University; Scientific Advisor, the 3D Anatomical Human European Institute / Project involving 7 countries; Advisory Professor, Chief Scientist and Chair of the International Advisory Committee, Med-X Research Institute, Shanghai Jiao Tong University; Guest Professor for a number of universities, including Tsinghua University. He received his M.E. in Electrical Engineering & Computer Science (EECS) from Shanghai Jiao Tong University in 1982, M.Sc. in Biocybernetics and Ph.D. in Computer Science from the University of California, Los Angeles (UCLA) in 1985 and 1988, respectively, where he received the Crump Prize for Excellence in Medical Engineering. In conjunction with his team members and students, he has been responsible for more than 50 key research projects, published over 900 scholarly research papers, pioneered several new research directions, and made a number of landmark contributions in his field. He has served as Chair of the International Federation of Automatic Control (IFAC) Technical Committee on Biological and Medical Systems, Special Area Editor / Associate Editor / Editorial Board Member for a dozen of core journals in his area, and Scientific Advisor for a number of prestigious organizations. He has been invited to give over 100 keynote presentations in 23 countries and regions, and has organized / chaired over 100 major international conferences / symposia / workshops. Professor Feng is Fellow of ACS, HKIE, IET, IEEE, and Australian Academy of Technological Sciences and Engineering.
Affiliations and expertise
Director, Biomedical & Multimedia Information Technology, School of Computer Science, University of Sydney, Sydney, Australia.

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