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Biomaterials for Precision Cancer Medicine

  • 1st Edition - October 4, 2024
  • Latest edition
  • Editors: Saeid Kargozar, Masoud Mozafari
  • Language: English

Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book d… Read more

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Description

Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book describes the various smart biomaterial-based treatments available, reviewing how they can be designed to target specific tumor types, adapt to changes in the cell microenvironment and offer smart, personalized therapy for different cancer variants, especially those which are drug-resistant. The book provides a materials-focused look at precision cancer medicine, and is thus useful to materials scientists, biomedical engineers, and biomedical scientists – including cancer and genetic specialists – with an interest in alternative cancer therapies.

Key features

  • Reviews the state-of-the-art in precision and translational medicine, setting the scene for the introduction of alternative biomaterial-based therapies
  • Covers a range of biomaterials for personalized cancer treatment, including polymer-protein conjugates, smart nanoparticles, metal compounds, and more
  • Addresses preclinical assessment, health risks, challenges and future perspective of precision anti-cancer biomaterials

Readership

Academics and researchers in materials science, engineering and biomedical engineering, Biomedical scientists, geneticists and cancer biologists

Table of contents

1. Introduction to cancer

2. Cancer therapy in the era of precision medicine

3. Precision medicine: Aspects in translational medicine

4. Biomaterials: Fundamentals, processing, and applications

5. Possible targets for biomaterials in cancer treatment

6. Biomaterials-based cancer diagnostics: Recent advances

7. Anti-cancer biomaterials: A special design for precision medicine

8. Natural plant-derived anti-cancer biomaterials

9. Combination cancer therapy by bio-macromolecules and small molecules

10. Biomaterials for cancer immunotherapy

11. Biomaterials for engineering tumor microenvironment

12. Biomaterials for cancer targeted drug delivery

13. Engineered smart biomaterials for anti-cancer gene delivery‏

14. Biofunctionalization of materials for targeting cancer cells

15. Reactive oxygen species (ROS)‐responsive materials in cancer therapy

16. Natural polymers for diagnosis and treatment of cancers

17. Synthetic polymers for malignancies treatment

18. Polymer-protein and polymer-drug conjugates in cancer therapy

19. Magnetic calcium phosphates for imaging and treating of cancers

20. Hydroxyapatite nanoparticles as anti-cancer agents

21. Bioactive magnetic glass-ceramics for cancer treatment

22. Mesoporous glasses in cancer therapy

23. Carbon biomaterials for cancer therapy: opportunities and challenges

24. Metals and metal compounds for cancer photothermal therapy

25. Smart nanoparticles for the treatment of drug-resistant tumors

26. Managing malignancies by magnetic electrospun nanofibers

27. Multiparametric preclinical assessment of theranostics materials

28. Health risk assessment of anti-cancer biomaterials

29. Future perspectives and challenges for biomaterials

Product details

  • Edition: 1
  • Latest edition
  • Published: October 10, 2024
  • Language: English

About the editors

SK

Saeid Kargozar

Saeid Kargozar is a Fellow of the University of Texas Southwestern Medical Center (UTSW), USA. He was previously a Senior Assistant Professor of Tissue Engineering in the Department of Anatomy and Cell Biology, at Mashhad University of Medical Sciences in Iran. He received his M.S. in Medical Biotechnology in 2012 and his Ph.D. in Tissue Engineering in 2016, both from Tehran University of Medical Sciences, Iran. His current research interests include biocompatible materials and tissue engineering with special focus on bioactive glasses and the decellularized extracellular matrix (ECM). He is an active member of the American Ceramic Society and has published more than 118 peer-reviewed publications. According to a recent scientometric study published in PLOS Biology in 2021, he is listed amongst the top 2% of cited scientists in the world.

Affiliations and expertise
UT Southwestern Medical Center

MM

Masoud Mozafari

Dr. Masoud Mozafari is a Fellow at Lunenfeld Tanenbaum Research Institute, Mount Sinai Health Hospital, University of Toronto. He was previously Assistant Professor and Director of the Bioengineering Lab, at the Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Cellular and Molecular Research Center, and Department of Tissue Engineering and Regenerative Medicine of the Iran University of Medical Sciences (IUMS), Tehran, Iran. Dr. Mozafari’s research interests range across biomaterials, nanotechnology, and tissue engineering, and he is known for the development of strategies for the treatment of damaged tissues and organs, and controlling biological substances for targeted delivery into the human body. Dr. Mozafari has received several awards, including the Khwarizmi Award and the Julia Polak European Doctorate Award for outstanding translational research contributions to the field of biomaterials. He has also received the WIPO Medal for Inventors from The World Intellectual Property Organization (WIPO), in recognition of his contributions to economic and technological development. Dr. Mozafari is currently working on the editorial board of several journals.
Affiliations and expertise
Research Fellow, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Canada

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